Abstract：
INTRODUCTION:In-transit cutaneous malignant melanoma metastases remains a difficult and distressing disease. It is a sequela to the primary lesion represented by melanoma deposits between the site of excision and the draining lymph nodes. We present our experience of carbon dioxide ablation of in-transit cutaneous malignant melanoma metastases and discuss the role of laser ablation as first-line management of the disease. METHOD:Using a departmental database and case notes, all patients who had undergone carbon dioxide laser ablation for malignant melanoma metastases in the authors' unit between December 1996 and December 2007 were reviewed. RESULTS:The total number of lesions ablated was 559 in 16 patients on 91 separate occasions. The mean number of lesions ablated at each treatment was 6 (range 4-200) and the mean number of treatments per patient was 5.7 (range 1-14). All patients had undergone previous surgical procedures for disease control (total 28, range 1-4). Ten patients remained clinically disease-free at 1-year follow-up. Of these ten patients. six achieved remission with a median time from first ablation of 7.5 years (range 2-10 years). CONCLUSION:Carbon dioxide laser ablation should be offered as first-line treatment in the management of cutaneous malignant melanoma metastases. A subgroup of patients were clinically disease-free with no systemic progression, following treatment, the reasons for which have not yet been fully explained.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Kandamany N,Mahaffey Pdoi
10.1007/s10103-008-0580-0subject
Has Abstractpub_date
2009-05-01 00:00:00pages
411-4issue
3eissn
0268-8921issn
1435-604Xjournal_volume
24pub_type
杂志文章abstract：:We observed the promoting effects of the 2940-nm erbium:YAG (Er:YAG) fractional laser in topical drug delivery for psoriasis. A total of five (four males and one female) recalcitrant psoriasis patients were given laser treatment eight times at 1-week intervals with the following parameters: 5-11% spot density and 100-...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-017-2259-x
更新日期：2017-08-01 00:00:00
abstract：:Laser therapy has proved effective in the treatment of different tissue injuries but little is known about its effect on the testis. The aim of this review was to synthesize research on the in vivo effect of low-level laser therapy on the seminiferous epithelium. A search was performed in the PubMed/Medline, Scopus, W...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-020-03122-y
更新日期：2020-08-19 00:00:00
abstract：:Knee osteoarthritis (KOA) is a common degenerative disease in which several treatments and treatment associations have been investigated. This review analyzed the efficacy of the association of photobiomodulation therapy (PBMT) and exercises for people with KOA in randomized controlled clinical trials. PubMed, Scopus,...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-020-03223-8
更新日期：2021-01-03 00:00:00
abstract：:Low-level laser therapy (LLLT) is a form of photon therapy which can be a non-invasive therapeutic procedure in cancer therapy using low-intensity light in the range of 450-800 nm. One of the main functional features of laser therapy is the photobiostimulation effects of low-level lasers on various biological systems ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2049-x
更新日期：2016-12-01 00:00:00
abstract：:The goal of this study was to assess the ablation, coagulation, and carbonization characteristics of the holmium:YAG (Ho:YAG) laser and thulium fiber lasers (TFL). The Ho:YAG laser (100 W av.power), the quasi-continuous (QCW) TFL (120 W av.power), and the SuperPulsed (SP) TFL (50 W av.power) were compared on a non-fro...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03189-7
更新日期：2020-11-11 00:00:00
abstract：:Delivery of intradermally focused nanosecond laser pulses with small energy as an alternate technique applicable to clinical procedures in dermatological and plastic surgery is an area of relatively new interest with multiple potential applications. We assessed this approach on common tattoo pigments in dermis in an i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030200025
更新日期：2002-01-01 00:00:00
abstract：:Cancer treatment with chemotherapy or radiotherapy is associated with some side effects including in the oral cavity. One of the more significant oral complications is oral mucositis (OM) which induces severe pain and limits fundamental life behaviors such as eating, drinking, and talking. Although advancements in can...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02757-w
更新日期：2019-09-01 00:00:00
abstract：:The objective of this study was to investigate the effect of Er:YAG laser irradiation on shear bond strength and microleakage between resin cements and yttrium-stabilized tetragonal zirconia (Y-TZP) ceramics. Eighty disc specimens of Y-TZP ceramics (6 mm × 4 mm) were prepared. The specimens were divided into two group...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0883-4
更新日期：2012-03-01 00:00:00
abstract：:The aim of this study is to analyze the effect of agitation of ethylenediaminetetraacetic acid (EDTA) with diode laser at different agitation times on root dentin microhardness. Eighty-four specimens were divided randomly into seven groups, as follows: (1) distilled water, (2) 17% EDTA, (3) EDTA with 60 s ultrasonic a...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1364-8
更新日期：2015-02-01 00:00:00
abstract：:This review aimed to identify the efficacy of low-level laser therapy (LLLT) in the management of orthodontic pain. This systematic review and meta-analysis was carried out in accordance with Cochrane Handbook and the PRISMA statement. An extensive literature search for RCTs, quasi-RCTs, and CCTs was performed through...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10103-012-1196-y
更新日期：2013-11-01 00:00:00
abstract：:The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2491-z
更新日期：2018-09-01 00:00:00
abstract：:The influence of Er:YAG laser irradiation on periodontal tissues along the root surface and apical region during root canal preparation was histologically evaluated using experimentally infected root canals of rats. Eighty experimentally mesial infected root canals of mandibular first molars in rats were divided into ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0804-y
更新日期：2011-11-01 00:00:00
abstract：:Low-level visible light irradiation was found to stimulate proliferation potential of various types of cells in vitro. Stem cells in general are of significance for implantation in regenerative medicine. The aim of the present study was to investigate the effect of low-level light irradiation on the proliferation of m...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1207-z
更新日期：2013-07-01 00:00:00
abstract：:The aim of this study is to evaluate the effectiveness of the low-level laser therapy (LLLT) in the control of pain, swelling, and trismus associated with surgical removal of impacted lower third molars. Thirty patients were randomized into two treatment groups, each with 15 patients-group test (LLLT) and a group cont...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-012-1174-4
更新日期：2013-05-01 00:00:00
abstract：:The aim of this study was to evaluate the effect of cavity preparation with Er:YAG laser on dentin adjacent to restorations submitted to cariogenic challenge in situ, by subsuperficial microhardness analysis. Bovine incisors were sectioned, flattened, and polished, resulting in 40 dentin slabs. The slabs were randomly...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2136-z
更新日期：2017-02-01 00:00:00
abstract：:We aimed at examining the effects of a percentage of air/water in spray on the cutting efficiency of Er,Cr:YSGG laser for enamel and dentin. The intensity and frequency of irradiation were 3.0 W and 20 Hz for the enamel surface and 2.0 W and 20 Hz for the dentin surface, respectively. Flattened surfaces of enamel and ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2607-5
更新日期：2019-02-01 00:00:00
abstract：:The published online version contains mistake. Warren S. Warren was not included in the author group section. Corrected author group section is shown above. ...
journal_title：Lasers in medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10103-017-2339-y
更新日期：2017-12-01 00:00:00
abstract：:The purpose of this study was to evaluate the acid resistance of erbium:yttrium-aluminum-garnet (Er:YAG) lased sub-surface dentin using a scanning electron microscope (SEM). Dentin disks were exposed to a single pulse of Er:YAG laser irradiation at 80 mJ/pulse under water spray, with the contact sapphire tip vertical ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0553-3
更新日期：2009-07-01 00:00:00
abstract：:Endometriosis is a chronic disease affecting mainly women of the reproductive age. Its most common manifestations include impaired fecundity, pelvic pain, and dyschezia. Laparoscopic removal of endometriotic foci remains to be the gold standard for the treatment of endometriosis. More effective techniques of endoscopi...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1630-4
更新日期：2015-01-01 00:00:00
abstract：:The laser source with 3 μm/2 μm output wavelength has many application prospects in clinical medicine, photoelectric countermeasure, and scientific research measurement. An Er3+ doped ZBLAN fiber laser with output wavelength of 2 .8 μm and 1 .6 μm is experimentally studied. By setting the pump power to 5 W, a continuo...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02766-9
更新日期：2019-10-01 00:00:00
abstract：:Acneiform rash associated with epidermal growth factor receptor inhibitors frequently presents facial manifestations. The treatment modality for such lesions still needs to be elucidated. The aim of this original report was to evaluate the effectiveness of high-level laser therapy in reducing the severity of facial ac...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1029-4
更新日期：2012-09-01 00:00:00
abstract：:To identify the best low level laser photobiomodulation application site at the same irradiation time to increase the viability of the skin flap in rats. Eighteen male rats (Rattus norvegicus: var. Albinus, Rodentia Mammalia) were randomly distributed into three groups (n = 6). Group I (GI) was submitted to simulated ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2694-3
更新日期：2019-07-01 00:00:00
abstract：:Antimicrobial photodynamic therapy (APDT) combined with endodontic treatment has been recognized as an alternative approach to complement conventional root canal disinfection methods on bacterial biofilms. We developed an in vitro model of bioluminescent Candida albicans biofilm inside curved dental root canals and i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1629-x
更新日期：2015-08-01 00:00:00
abstract：:A nevus is described as a benign, often pigmented, skin growth that can be congenital or acquired. Different types of nevi are located at different depths within the skin. Traditional treatments for nevi include topical treatments, dermabrasion, and excision, which are generally ineffective, invasive, and often result...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-014-1697-y
更新日期：2015-09-01 00:00:00
abstract：:In this study, we compared the microleakage of composite fillings cured with halogen bulb, LED and argon ion laser (488 nm). Twenty-four extracted human molars were divided randomly in three groups. Six cavities were prepared on the coronal part of each tooth. Standard cavities (1.7 x 2 mm) were prepared. Cavities wer...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0504-4
更新日期：2009-01-01 00:00:00
abstract：:The purpose of this article was to analyze the photobiomodulator role of low-level laser therapy (LLLT) on the skeletal muscle remodeling following cryoinjury in rats, focusing the types I and III collagen proteins. Laser phototherapy has been employed to stimulate repair in different tissues. However, its role in ske...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0951-9
更新日期：2011-11-01 00:00:00
abstract：:Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder characterized by skin tumours derived from peripheral nerves. It is a clinically diagnosed disorder of a mainly cosmetic concern. There are different excision modalities for treatment of cutaneous neurofibromas; however, none is considered to be univers...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0485-3
更新日期：2008-07-01 00:00:00
abstract：:Third-degree burn wounds are considered severe injuries because they destroy all the skin layers and may affect subcutaneous tissues, fasciae, muscles, and bones. To favor the healing process of the injured tissues, it is very useful to diminish the occurrence of the inflammatory process. The present study was aimed a...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1213-1
更新日期：2013-07-01 00:00:00
abstract：:Low-intensity laser therapy (LILT) has been considered as a treatment modality in diabetic distal symmetric polyneuropathy (DSP). The aim of this study is to determine the effectiveness of LILT on DSP. We examined 107 subjects with type 2 diabetes for detection of DSP using the Michigan Neuropathy Screening Instrument...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0977-z
更新日期：2011-11-01 00:00:00
abstract：:The aim of this work was to investigate the long-term effects of a single application of a water-cooled pulsed neodymium yttrium aluminium garnet (Nd:YAG) laser, in combination with scaling and root planing (SRP) for the treatment of periodontal inflammation. Twenty-two patients were included in this split-mouth singl...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-010-0807-8
更新日期：2011-11-01 00:00:00
