Abstract:
:A disrupted wound repair process often leads to the development of chronic wounds, and pose a major physical, social and economic inconvenience on patients and the public health sector. Chronic wounds are a common complication seen in diabetes mellitus (DM), and often the severity necessitates amputation of the lower limbs. Recently, there has been increasing evidence that photobiomodulation (PBM) initiates wound healing, including increased protein transcription for cell proliferation, viability, migration and tissue reepithelialisation. Here, the hypothesis that PBM at a wavelength of 660 nm and energy density of 5 J/cm2 regulates wound repair in diabetic wounded and hypoxic diabetic wounded fibroblasts by enhancing cell migration and survival was investigated. PBM increased migration and survival in diabetic wounded and hypoxic diabetic wounded fibroblasts. Our findings suggest that PBM enhances migration and survival in diabetic wounded and hypoxic diabetic wounded fibroblasts, indicating that this therapeutic method may be beneficial against chronic wounds in diabetic patients.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Jere SW,Houreld NN,Abrahamse Hdoi
10.1007/s10103-020-03041-ysubject
Has Abstractpub_date
2020-06-01 00:00:00eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-020-03041-ypub_type
杂志文章abstract::The purpose of this study was to evaluate the acid resistance of erbium:yttrium-aluminum-garnet (Er:YAG) lased sub-surface dentin using a scanning electron microscope (SEM). Dentin disks were exposed to a single pulse of Er:YAG laser irradiation at 80 mJ/pulse under water spray, with the contact sapphire tip vertical ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0553-3
更新日期:2009-07-01 00:00:00
abstract::Antibiotics and photodynamic therapy (PDT) are widely employed in curing acne. However, antibiotics as an effective treatment would lead to bacterial resistance and severe side effects. In this study, we aimed to develop a novel TBO hydrogel, which could prolong the retention time of photosensitizer (TBO) at the lesio...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02727-2
更新日期:2019-10-01 00:00:00
abstract::In this study, the impact of two-dimensional (2D) and three-dimensional (3D) vision on laparoscopic performance of novice surgeons is examined. Twenty-five novice surgeons were directed to complete four basic tasks from European Training in Basic Laparoscopic Urological Skills (E-BLUS) with both 2D and 3D systems in a...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1739-0
更新日期:2015-05-01 00:00:00
abstract::Low-level laser therapy (LLLT) is a form of photon therapy which can be a non-invasive therapeutic procedure in cancer therapy using low-intensity light in the range of 450-800 nm. One of the main functional features of laser therapy is the photobiostimulation effects of low-level lasers on various biological systems ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-2049-x
更新日期:2016-12-01 00:00:00
abstract::Skin flaps are still a matter of concern among surgeons, as failures can occur leading to flap necrosis. However, low-level laser irradiation has been reported as an effective tool to improve the viability of ischemic flaps, yet its mechanisms of action remain unclear. We investigated the effect of low-level laser irr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-1011-1
更新日期:2012-05-01 00:00:00
abstract::The effect of the 488-nm wavelength of argon laser at different power densities and irradiation times on the degree of conversion (DC), temperature rise, water sorption, solubility, flexural strength, flexural modulus, and microhardness of bisphenole A glycol dimethacrylate and triethylen glycol dimethacrylate with a ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-007-0487-1
更新日期:2008-10-01 00:00:00
abstract::The aim of this in vitro study was to evaluate some parameters of dental etching when irradiated with an erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser. One-hundred sound human third molars were selected and randomly distributed into ten groups (n = 10). The class V cavities of group 1 (control) w...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0623-6
更新日期:2010-05-01 00:00:00
abstract::This study aimed to evaluate in vitro performance of near-infrared laser transillumination (NIR-LTI) for detecting early occlusal caries in permanent teeth and compare it with quantitative light-induced fluorescence (QLF), DIAGNOdent Pen (DDPen), and conventional radiography (CR). Ninety-four occlusal surfaces present...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1704-3
更新日期:2015-09-01 00:00:00
abstract::In periodontal therapy, the use of low-level diode lasers has recently been considered to improve wound healing of the gingival tissue. However, its effects on human gingival epithelial cells (HGECs) remain unknown. The aim of the present study was to examine whether high-frequency low-level diode laser irradiation st...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1292-7
更新日期:2014-07-01 00:00:00
abstract::This ablation rate study has been carried out with a fibre-deliverable, 308 nm, XeCl laser, producing long pulses of 200 ns as opposed to the usual 10-20 ns. This in-depth study aimed to evaluate the ablation rates for this longer pulse length. The effects on the ablation depth of dentine, enamel, soft tissue and bone...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-004-0315-9
更新日期:2004-01-01 00:00:00
abstract::Bisphosphonate-related osteonecrosis of the jaw is a well-known potential side effect of long-term bisphosphonate therapy; the primary objective of the treatment should be to improve patient quality of life through pain and infection management, to prevent the development of new lesions, and to slow disease progressio...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-016-1929-4
更新日期:2016-08-01 00:00:00
abstract::Oral lichen planus (OLP) is an inflammatory disease that can be painful, mainly in the atrophic and erosive forms. Numerous drugs have been used with dissimilar results, but most treatments are empirical. However, to date, the most commonly employed and useful agents for the treatment of OLP are topical corticosteroid...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-013-1313-6
更新日期:2014-01-01 00:00:00
abstract::Laser angioplasty has been evaluated for coronary applications since the early 1980s. Early complications of dissection, perforation and thermal injury led to a loss of enthusiasm for this technique. Recent advances in catheter development, including optimally spaced laser fibres, athermic 308 nm wave-length catheters...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/pl00011338
更新日期:2001-01-01 00:00:00
abstract::Gingival melanin hyperpigmentation is an esthetic concern for many individuals. In this study, we compared the standard surgical removal method with two different Er,Cr:YSGG laser settings in order to find the best treatment method. In 33 dental arches, the following three treatment groups were comparatively evaluated...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2501-1
更新日期:2018-11-01 00:00:00
abstract::Corrosiveness of enamel surfaces of Smartbleach, Opus White, Opalescense Xtra Boost and a gel containing titanium dioxide (TiO(2)) particles, activated either by a frequency doubled neodymium: yttrium-aluminum-garnet (Nd:YAG) laser (532 nm) or a diode laser (810 nm) was evaluated by environmental scanning electron mic...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0567-x
更新日期:2009-05-01 00:00:00
abstract::A nevus is described as a benign, often pigmented, skin growth that can be congenital or acquired. Different types of nevi are located at different depths within the skin. Traditional treatments for nevi include topical treatments, dermabrasion, and excision, which are generally ineffective, invasive, and often result...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-014-1697-y
更新日期:2015-09-01 00:00:00
abstract::The published online version contains mistake. Warren S. Warren was not included in the author group section. Corrected author group section is shown above. ...
journal_title:Lasers in medical science
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10103-017-2339-y
更新日期:2017-12-01 00:00:00
abstract::This in vitro study evaluated the role of photobiomodulation therapy (PBMT) on viability and migration of human dental pulp stem cells (hDPSCs) and its association to epigenetic mechanisms such as histone acetylation. The hDPSCs were characterized and assigned into control and PBMT groups. For the PBMT, five laser irr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02931-0
更新日期:2020-04-01 00:00:00
abstract::The aim of this study was to evaluate the bactericidal effect of ultraviolet (UV) light at 265-nm (UVC) and 310-nm (UVB) wavelengths from a newly developed UV light-emitting diode (LED) device against cariogenic bacteria in vitro. Suspensions of Streptococcus mutans (S. mutans) and Streptococcus sobrinus were directly...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2685-4
更新日期:2019-07-01 00:00:00
abstract::Photobiomodulation (PBM) has been shown to improve wound healing by promoting mesenchymal stem cell migration and proliferation. However, it remains unknown whether an 808-nm diode laser can influence human gingival mesenchymal stem cells (HGMSCs), and which dose this works well. In the present study, it was found tha...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03040-z
更新日期:2020-10-01 00:00:00
abstract::Low-back pain is very frequent, especially in active adult population. There are several different orthopaedic condition that can cause low-back pain, and the pain worsen the quality of life significantly. The treatments vary from drugs, physical therapies, kinesiology, local infiltrations, and so on. Laser therapy ha...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-014-1684-3
更新日期:2015-01-01 00:00:00
abstract::We assess the long-term effect of pulsed high-intensity laser therapy (HILT) in the treatment of the post-mastectomy pain syndrome (PMPS). A total of 61 women participated in this study (30 in the laser group and 31 in the placebo laser group), with a mean age of 53.56 ± 1.11 years. Patients who were randomly assigned...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-015-1780-z
更新日期:2015-08-01 00:00:00
abstract::Down syndrome (DS) has characteristics that include mental retardation, a characteristic phenotype, congenital heart defects, immune disorders, and increased risk of periodontal disease (PD). Antimicrobial photodynamic therapy (aPDT) is the combined use of photosensitizers associated with low-level laser (LLL) and oxy...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-016-2020-x
更新日期:2016-12-01 00:00:00
abstract::The bactericidal activity of a pulsed fibre-optic Nd-YAP laser on various strains of oral bacteria: Prevotella nigrescens, Streptococcus sanguis, Actinomyces viscosus (i), Fusobacterium nucleatum, Actinobacillus actinomycetemcomitans and Peptostreptococcus micros (i) was evaluated. A 200-μm optical fibre was placed in...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s101030050010
更新日期:1998-12-01 00:00:00
abstract::Laser therapy is able to modulate cell metabolism and accelerate the repair of fracture. Little attention has been given to the effect of laser on bone with osteopenia or osteoporosis. The purpose of our study was to verify the effect of laser therapy in combination with bisphosphonate on osteopenic bone structure. Th...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0568-9
更新日期:2009-05-01 00:00:00
abstract::Although ear reconstruction technology has been highly developed in recent years, hair growth on the reconstructed ear has plagued both surgeons and patients. In this paper, the authors introduce a clinical application of intense pulsed light depilation in total auricular reconstruction. From August 2012 to August 201...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-017-2255-1
更新日期:2017-08-01 00:00:00
abstract::Salt is an essential and important dietary mineral for maintaining life. Currently, the issue of the potential benefit or damage from salt intake in chronic kidney disease patients is controversial. The attempt of this article is to bring into focus the potential role of elements particularly sodium, Na, and potassium...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-009-0659-2
更新日期:2009-11-01 00:00:00
abstract::The aim of this study was to compare the effects of Nd:YAG, Er:YAG, and diode lasers on the morphology and permeability of root canal walls. The three laser wavelengths mentioned interact differently with dentin and therefore it is possible that the permeability changes caused will determine different indications duri...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0775-z
更新日期:2010-09-01 00:00:00
abstract::The purposes of the study were to evaluate the bond strength of bioceramic TotalFill root repair material (RRM) in retrograde cavities prepared using Er:YAG and Er,Cr:YSGG laser and steel bur, and to analyze failure modes. The root canals of 30 single-rooted teeth were endodontically treated, their root-ends were rese...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02835-z
更新日期:2020-02-01 00:00:00
abstract::Our objective was to assess the efficacy and safety of combined 10.6 microm and 650 nm laser irradiation on patients with knee osteoarthritis (OA). Forty patients with OA were randomly allocated to an active laser group or to a placebo laser group (20 per group). They either received active or sham laser treatment at ...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-007-0536-9
更新日期:2009-03-01 00:00:00