Abstract：
:Our objective was to assess the efficacy and safety of combined 10.6 microm and 650 nm laser irradiation on patients with knee osteoarthritis (OA). Forty patients with OA were randomly allocated to an active laser group or to a placebo laser group (20 per group). They either received active or sham laser treatment at acupoint Dubi (ST 35) in a total of 12 sessions. There was significant difference between the two groups in the Western Ontario and McMaster Universities (WOMAC) osteoarthritis index pain score change from baseline after 2 weeks of treatment (P = 0.047). The pain reduction of the active laser treatment group was 49%, whereas that of the placebo control group was only 13%. However, due to the high patient drop-out rate, the 4-week assessment could not be analyzed. Combined laser treatment seems beneficial to patients with knee OA. However, due to the small sample size and the high drop-out rate of patients in the placebo group, a large sample-size clinical trial is warranted to determine further the therapeutic efficacy of the device.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Shen X,Zhao L,Ding G,Tan M,Gao J,Wang L,Lao Ldoi
10.1007/s10103-007-0536-9subject
Has Abstractpub_date
2009-03-01 00:00:00pages
129-36issue
2eissn
0268-8921issn
1435-604Xjournal_volume
24pub_type
杂志文章,随机对照试验abstract：:The aims of this study were to evaluate the effects of Photogem®-mediated photosensitization on rat palatal mucosa and the biodistribution of the photosensitizer in this tissue. A solution of Photogem® (500 or 1000 mg/l) was applied to the palatal mucosa for 30 min and the exposure time to blue LED (460 nm) was 20 min...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0909-y
更新日期：2012-03-01 00:00:00
abstract：:Acupuncture is a form of traditional Chinese medicine that has developed over thousands of years. We studied the effects of laser puncture, needle acupuncture, and light stimulation on cerebral blood flow in 15 healthy volunteers (mean age 25.0±1.9 years, 5 female, 10 male) with non-invasive transcranial Doppler sonog...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030050048
更新日期：2000-01-01 00:00:00
abstract：:Acne vulgaris is one of the most common dermatologic disorders encountered in everyday practice. Treatment options for this often psychologically scarring disease are numerous and, for many individuals, provide relief from the disorder. However, factors such as antibiotic resistance and slow onset of action from many ...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-006-0420-z
更新日期：2007-06-01 00:00:00
abstract：:The goal of this study was to assess the ablation, coagulation, and carbonization characteristics of the holmium:YAG (Ho:YAG) laser and thulium fiber lasers (TFL). The Ho:YAG laser (100 W av.power), the quasi-continuous (QCW) TFL (120 W av.power), and the SuperPulsed (SP) TFL (50 W av.power) were compared on a non-fro...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03189-7
更新日期：2020-11-11 00:00:00
abstract：:Laser micromachining with ultrashort pulses has shown great promise for clean, safe surgical treatment of bone tissue. However, comparisons of performance and development of "best practice" have been hampered by the difficulty of comparing results across a wide variety of experimental approaches and under surgically i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02899-x
更新日期：2020-08-01 00:00:00
abstract：:Most of the widely used scales to evaluate scars are subjective relying on clinical observations. There is a growing need to find out a noninvasive objective tool for this purpose. The study is aimed at evaluating the value of the high-resolution ultrasound in the assessment of the scars when compared with a clinical ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02830-4
更新日期：2020-03-01 00:00:00
abstract：:Microvascular surgery is time consuming and requires high expertise. Laser-assisted vascular anastomosis (LAVA) is a promising sutureless technique that has the potential to facilitate this procedure. In this study, we evaluate the handling of our soldering material and the 1-week patency rate in a porcine model. Six ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2250-6
更新日期：2017-08-01 00:00:00
abstract：:The efficacy of intense pulsed light (IPL) in remodeling the extracellular matrix of aged skin had been proven by an increasing number of clinical trials. However, because of the lack of research about the underlying molecular and signaling mechanisms, its efficiency had not been accepted universally. A potential mech...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0870-1
更新日期：2011-05-01 00:00:00
abstract：:Facial vitiligo has considerable psychological and emotional impacts. Though topical corticosteroids are the mainstay treatment, adverse reactions are a concern for prolonged use. Additionally, 308-nm excimer lamps have been widely used in vitiligo. This study aimed to assess the effectiveness of a combined 308-nm exc...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-020-03048-5
更新日期：2020-12-01 00:00:00
abstract：:This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0590-y
更新日期：2009-07-01 00:00:00
abstract：:The neodymium/yttrium-aluminum-garnet (Nd/YAG) laser has been suggested to repair broken prostheses in the mouth. This study investigated the effects of different dentin thicknesses and air cooling on pulpal temperature rise during laser welding. Three intact human maxillary molars were prepared for full-veneer crown....
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1108-1
更新日期：2013-01-01 00:00:00
abstract：:Corrosiveness of enamel surfaces of Smartbleach, Opus White, Opalescense Xtra Boost and a gel containing titanium dioxide (TiO(2)) particles, activated either by a frequency doubled neodymium: yttrium-aluminum-garnet (Nd:YAG) laser (532 nm) or a diode laser (810 nm) was evaluated by environmental scanning electron mic...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0567-x
更新日期：2009-05-01 00:00:00
abstract：:Wound healing is a very complex process, some phases of which have only recently been explained. Magnetic and electromagnetic fields can modulate this process in a non-thermal way. The aim of this research was to compare the influence of constant and pulsed electromagnetic fields and low-level laser therapy (LLLT) on ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0564-0
更新日期：2009-05-01 00:00:00
abstract：:To evaluate the efficacy of laser fibrotomy in patients with oral submucous fibrosis (OSMF) and also to correlate the habit variables causing OSMF. Thirty patients diagnosed clinically and histopathologically with OSMF were included in the study. Laser fibrotomy was done under local anesthesia using Zolar diode laser ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-018-2531-8
更新日期：2018-11-01 00:00:00
abstract：:The aim of this study was to determine whether it is safe to use photo-activated disinfection (PAD) during root canal treatment without heating the periodontal tissues. Root canals of 30 freshly extracted single-rooted teeth were prepared using ProFiles up to size ISO 40 and then filled with photo-sensitiser: tolonium...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0526-y
更新日期：2009-01-01 00:00:00
abstract：:The bond strength of resin composite to Er,Cr:YSGG laser-irradiated enamel and dentin has been evaluated in only a few studies. Therefore, we measured and compared the micro-shear bond strength of composite restorations to enamel and dentin using two different cavity-preparation tools and conditioning methods. One hun...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0961-7
更新日期：2012-07-01 00:00:00
abstract：:Tissue characterisation by fluorescence imaging, using exogenous fluorophores, is a promising method for cancer detection. Histochemical alterations in the composition of mucins, when neoplastic transformations occur, could be exploited to derive more selective fluoroprobes indicative of early malignant transformation...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/pl00011361
更新日期：2001-01-01 00:00:00
abstract：:The present study was designed to evaluate the effects of low-level laser (Nd:YAG) therapy and occlusal splints in patients with signs and symptoms of temporomandibular disorders (TMD) characterized with myofascial pain (MP). A total of 30 patients were selected after being diagnosed with MP according to the Research ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-014-1522-7
更新日期：2015-04-01 00:00:00
abstract：:Photobiomodulation is a treatment that has been widely used in neurotrauma and neurodegenerative diseases. In the present study, low-level laser therapy was administered to patients with spinal cord injury. Twenty-five individuals were divided into two groups: placebo photobiomodulation plus physiotherapy and active p...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2447-3
更新日期：2018-05-01 00:00:00
abstract：:Antimicrobial photodynamic therapy (APDT) combined with endodontic treatment has been recognized as an alternative approach to complement conventional root canal disinfection methods on bacterial biofilms. We developed an in vitro model of bioluminescent Candida albicans biofilm inside curved dental root canals and i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1629-x
更新日期：2015-08-01 00:00:00
abstract：:The purpose of this study is to evaluate microtensile bond strength (μTBS) of an etch-and-rinse adhesive to enamel and dentin after treatment with Er:YAG laser using different pulse durations. Extracted human molars were flattened to obtain enamel or dentin surfaces. The enamel specimens (E) were divided into nine gro...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0830-9
更新日期：2012-01-01 00:00:00
abstract：:A novel skin phantom is described that is constructed with quantifiable amounts of skin pigments, as well as a light scattering medium in the form of barium sulphate suspension. The two predominant skin pigments (melanin and haemoglobin) are varied in controlled amounts within the phantoms to simulate skin colour in d...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0495-1
更新日期：2008-10-01 00:00:00
abstract：:This in vitro study evaluated the role of photobiomodulation therapy (PBMT) on viability and migration of human dental pulp stem cells (hDPSCs) and its association to epigenetic mechanisms such as histone acetylation. The hDPSCs were characterized and assigned into control and PBMT groups. For the PBMT, five laser irr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02931-0
更新日期：2020-04-01 00:00:00
abstract：:Skin flaps are still a matter of concern among surgeons, as failures can occur leading to flap necrosis. However, low-level laser irradiation has been reported as an effective tool to improve the viability of ischemic flaps, yet its mechanisms of action remain unclear. We investigated the effect of low-level laser irr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1011-1
更新日期：2012-05-01 00:00:00
abstract：:We describe the diversity of indications for laser hair removal (LHR) therapy and compare our experience with the literature. Patients' case notes referred to the Birmingham Regional Skin Laser Centre between 2003 and 2011 for laser hair removal, with indications other than hirsutism, were reviewed retrospectively. Th...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-013-1464-5
更新日期：2015-01-01 00:00:00
abstract：:Although the application of Q-switched lasers on nevus of Ota (OTA) is well demonstrated, debates about clinical option between Q-switched alexandrite laser (QSA) and Q-switched Nd:YAG laser (QSNY) still remain. This systematic review and meta-analysis estimated the overall successful rate of OTA pigment clearance and...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10103-016-1885-z
更新日期：2016-04-01 00:00:00
abstract：:A growing number of laboratory and clinical studies over the past 10 years have shown that low-level laser stimulation (633 or 670 nm) at extremely low power densities (about 0.15 mW/cm(2)), when administered through a particular emission mode, is capable of eliciting significant biological effects. Studies on cell cu...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-010-0837-2
更新日期：2011-01-01 00:00:00
abstract：:The purpose of this in vitro study was to observe the morphological changes and apical dye penetration at apical dentin surfaces after apicoectomy with conventional techniques and laser beam. Sixty single-rooted extracted teeth were selected for the study. The crowns were resected below the cemento-enamel junction. Th...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0497-z
更新日期：2008-10-01 00:00:00
abstract：:Scars from self-inflicted wounds, referred to as "hesitation marks," are usually linear, flat, poorly oriented, white in color, and often located on the forearm. Many patients do not undergo treatment for these due to limited available modalities. The aim of this study was to evaluate the efficacy and safety of the pi...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1981-0
更新日期：2016-09-01 00:00:00
abstract：:Photofrin photodynamic therapy (PDT) is a licenced treatment for Barrett's oesophagus (BE) with high-grade dysplasia (HGD) but causes strictures and photosensitivity and complete reversal of dysplasia (CR-HGD) by 50 % at 5 years. 5-Aminolaevulinic acid (ALA) is an alternative treatment with non-randomised data suggest...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-012-1132-1
更新日期：2013-05-01 00:00:00
