Abstract：
:There is concern that the delicate fibres and cylindrical diffuser tips used for intraluminal PDT of blood vessels might break during the treatment. We have developed and tested a simple system to monitor for fibre breakage during PDT. Light from the laser is passed through a beam expander, then a beam splitter, and then is again contracted into the inlet of a diffuser fibre. Light reflected from the distal diffuser is also partially reflected by the beam splitter into a photodiode, which monitors changes in the intensity of the reflected light. The system was tested by simulating catastrophic failures in four fibres. In each case the output fell very significantly (DV=0.44-1.68 V, SD=0.01 V). Despite the small statistical sample, the average change in the reflected light intensity is still significant (p < 0.025, paired Student's t-test). Our conclusion was that this device can monitor the integrity of diffuser fibres during PDT.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Mosse CA,Theodossiou T,Mills TNdoi
10.1007/s10103-003-0270-xsubject
Has Abstractpub_date
2003-01-01 00:00:00pages
162-4issue
3eissn
0268-8921issn
1435-604Xjournal_volume
18pub_type
杂志文章abstract：:The aim of this work was to investigate the long-term effects of a single application of a water-cooled pulsed neodymium yttrium aluminium garnet (Nd:YAG) laser, in combination with scaling and root planing (SRP) for the treatment of periodontal inflammation. Twenty-two patients were included in this split-mouth singl...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-010-0807-8
更新日期：2011-11-01 00:00:00
abstract：:This in vitro study evaluated the role of photobiomodulation therapy (PBMT) on viability and migration of human dental pulp stem cells (hDPSCs) and its association to epigenetic mechanisms such as histone acetylation. The hDPSCs were characterized and assigned into control and PBMT groups. For the PBMT, five laser irr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02931-0
更新日期：2020-04-01 00:00:00
abstract：:Interstitial laser Doppler flowmetry was used to measure the effect of interstitial laser-induced thermotherapy on local blood perfusion in normal rat liver in the peripheral treatment region elevated to hyperthermic temperatures. The Nd:YAG laser emitting at 1064 nm was utilised as heat generation source. The plane-c...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030050036
更新日期：1999-06-01 00:00:00
abstract：:In spinal cord injury (SCI), inflammation is a major mediator of damage and loss of function and is regulated primarily by the bone marrow-derived macrophages (BMDMs). Photobiomodulation (PBM) or low-level light stimulation is known to have anti-inflammatory effects and has previously been used in the treatment of SCI...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02941-y
更新日期：2020-09-01 00:00:00
abstract：:Induction of matrix synthesis by low-level laser has been demonstrated extensively. However, the question of dose- or power intensity-dependency is under-investigated. To address this issue we chose human osteoblast cell cultures and measured their alkaline phosphatase (ALP) activity after laser irradiation. The cell ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0511-5
更新日期：2008-10-01 00:00:00
abstract：:This study aimed to evaluate the surface changes caused in zirconia by different surface treatments and the influence of the surface treatment and cement selection on bonding to zirconia under aging. Sintered zirconia specimens were divided into five groups (n = 31) based on the surface treatment, namely, control, air...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1221-1
更新日期：2014-01-01 00:00:00
abstract：:The aim of this study was to evaluate the degree of conversion (DC) and to identify the viscoelastic properties: storage modulus (E'), loss modulus (E"), tangent delta (tan δ), and glass transition temperature (T g ) of a microhybrid resin-composite light-activated by three different protocols. A Filtek Z250 (3 M ESPE...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1572-x
更新日期：2015-05-01 00:00:00
abstract：:This ablation rate study has been carried out with a fibre-deliverable, 308 nm, XeCl laser, producing long pulses of 200 ns as opposed to the usual 10-20 ns. This in-depth study aimed to evaluate the ablation rates for this longer pulse length. The effects on the ablation depth of dentine, enamel, soft tissue and bone...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0315-9
更新日期：2004-01-01 00:00:00
abstract：:The present investigation focuses on understanding the role of photobiomodulation in enhancing tissue proliferation. Circular excision wounds of diameter 1.5 cm were created on Swiss albino mice and treated immediately with 2 J/cm2 and 10 J/cm2 single exposures of the Helium-Neon laser along with sham-irradiated contr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03202-z
更新日期：2020-11-27 00:00:00
abstract：:Photosensitizers belonging to the boron-dipyrromethenes (BODIPYs) class were recently found endowed with good efficacy in the antibacterial photodynamic therapy (aPDT) against both Gram-positive and Gram-negative bacteria. In this paper, we report on the remarkable adjuvant effect exerted in this respect by linear pol...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2345-0
更新日期：2018-08-01 00:00:00
abstract：:Our objective was to assess the efficacy and safety of combined 10.6 microm and 650 nm laser irradiation on patients with knee osteoarthritis (OA). Forty patients with OA were randomly allocated to an active laser group or to a placebo laser group (20 per group). They either received active or sham laser treatment at ...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-007-0536-9
更新日期：2009-03-01 00:00:00
abstract：:We evaluated the acute electrophysiological effects of low-energy pulsed laser irradiation on isolated frog sciatic nerve measured by extracellular recording technique. A pulsed gallium-arsenide (GaAs) laser (wavelength: 904 nm, pulse duration 220 ns, peak power per pulse: 27W, spot size: 0.28 cm(2), total applied ene...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-002-8268-3
更新日期：2002-01-01 00:00:00
abstract：:Despite the positive effects of low-level laser therapy (LLLT) on muscle fatigue before exercises using a single muscle group, the acute effects of LLLT on performance in cardiopulmonary exercise testing (CPET) are poorly understood. We aimed to assess the acute effects of LLLT on physiologic and electromyographic res...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-014-1595-3
更新日期：2014-11-01 00:00:00
abstract：:A retrospective study was conducted to investigate the incidence of reported adverse responses after epilatory laser treatment to control the growth of facial hair in patients with polycystic ovary syndrome. Forty-eight patients received a median of 6 (range 2-11) treatments with an Aesculap ruby laser during a 704 da...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0451-0
更新日期：2008-01-01 00:00:00
abstract：:We assess the long-term effect of pulsed high-intensity laser therapy (HILT) in the treatment of the post-mastectomy pain syndrome (PMPS). A total of 61 women participated in this study (30 in the laser group and 31 in the placebo laser group), with a mean age of 53.56 ± 1.11 years. Patients who were randomly assigned...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-015-1780-z
更新日期：2015-08-01 00:00:00
abstract：:The aim of this study was to determine whether it is safe to use photo-activated disinfection (PAD) during root canal treatment without heating the periodontal tissues. Root canals of 30 freshly extracted single-rooted teeth were prepared using ProFiles up to size ISO 40 and then filled with photo-sensitiser: tolonium...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0526-y
更新日期：2009-01-01 00:00:00
abstract：:Laser micromachining with ultrashort pulses has shown great promise for clean, safe surgical treatment of bone tissue. However, comparisons of performance and development of "best practice" have been hampered by the difficulty of comparing results across a wide variety of experimental approaches and under surgically i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02899-x
更新日期：2020-08-01 00:00:00
abstract：:The aim of this study was to histologically and biochemically analyze the effects of light-emitting diode therapy (LEDT) associated with resistance training to prevent sarcopenia in ovariectomized rats. Forty female Wistar rats (12 months old, 295-330 g) were bilaterally ovariectomized and divided into four groups (n ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1251-8
更新日期：2013-11-01 00:00:00
abstract：:We report the use of spectral domain polarization sensitive optical coherence tomography for ex-vivo imaging of human oral mandibular tissue samples. Our results show that compared to the changes observed in the epithelium thickness and the decay constant of A-scan intensity profile, a much larger degree of change was...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2096-3
更新日期：2017-01-01 00:00:00
abstract：:Oral mucositis (OM) and radiodermatitis (RD) are serious side effects of radiotherapy (RT), often leading to its suspension, need for analgesics, and enteral/parenteral nutrition. Laser therapy is becoming a recommended treatment option. This prospective study aimed at demonstrating the beneficial effect of class IV l...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1857-8
更新日期：2016-04-01 00:00:00
abstract：:The aim of this study was to evaluate the bactericidal effect of ultraviolet (UV) light at 265-nm (UVC) and 310-nm (UVB) wavelengths from a newly developed UV light-emitting diode (LED) device against cariogenic bacteria in vitro. Suspensions of Streptococcus mutans (S. mutans) and Streptococcus sobrinus were directly...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2685-4
更新日期：2019-07-01 00:00:00
abstract：:The purpose of this article was to analyze the photobiomodulator role of low-level laser therapy (LLLT) on the skeletal muscle remodeling following cryoinjury in rats, focusing the types I and III collagen proteins. Laser phototherapy has been employed to stimulate repair in different tissues. However, its role in ske...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0951-9
更新日期：2011-11-01 00:00:00
abstract：:We aimed at examining the effects of a percentage of air/water in spray on the cutting efficiency of Er,Cr:YSGG laser for enamel and dentin. The intensity and frequency of irradiation were 3.0 W and 20 Hz for the enamel surface and 2.0 W and 20 Hz for the dentin surface, respectively. Flattened surfaces of enamel and ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2607-5
更新日期：2019-02-01 00:00:00
abstract：:In an in vitro study, the effect of light polarization on the efficiency of 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) of basal cell carcinoma (BCC) was investigated. Three states of light polarization (non-polarized, linearly polarized, and circularly polarized) were considered. Cells were exposed to gre...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2369-5
更新日期：2018-02-01 00:00:00
abstract：:Recent studies have shown that direct laser metal sintering (DLMS) produces structures with complex geometry and consequently that allow better osteoconductive properties. The aim of this patient report was to evaluate the early bone response to DLMS implant surface retrieved from human jaws. Four experimental DLMS im...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0831-8
更新日期：2011-01-01 00:00:00
abstract：:Low-level laser irradiation (LLLI) and recombinant human bone morphogenetic protein type 2 (rhBMP-2) have been used to stimulate bone formation. LLLI stimulates proliferation of osteoblast precursor cells and cell differentiation and rhBMP-2 recruits osteoprogenitor cells to the bone healing area. This in vivo study e...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1022-y
更新日期：2012-09-01 00:00:00
abstract：:Use of the CO(2) laser (λ = 10.6 μm, continuous wave, defocused) is an established procedure for the treatment of premalignant lesions. Through employment of the sp-mode as well as scanners, thermal laser effects can be reduced but, on the other hand, a lesser degree of destruction of dysplastic cells could lead to an...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-011-0910-5
更新日期：2012-01-01 00:00:00
abstract：:The purpose of this study is twofold: (1) to determine the feasibility of optical coherence tomography (OCT) to differentiate normal and diseased tissue of the neck region intraoperatively and (2) to evaluate how accurately a cohort of test subjects can identify various tissue types when shown a sample set of OCT imag...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03024-z
更新日期：2020-04-27 00:00:00
abstract：:Liquid-assisted hard tissue ablation by infrared lasers has extensive clinical application. However, detailed studies are still needed to explore the underlying mechanism. In the present study, the dynamic process of bubble evolution induced by Ho:YAG laser under water without and with bone tissue at different thickne...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1931-x
更新日期：2016-07-01 00:00:00
abstract：:Photobiomodulation (PBM) has been shown to improve wound healing by promoting mesenchymal stem cell migration and proliferation. However, it remains unknown whether an 808-nm diode laser can influence human gingival mesenchymal stem cells (HGMSCs), and which dose this works well. In the present study, it was found tha...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03040-z
更新日期：2020-10-01 00:00:00
