Abstract：
:Transoral laser microsurgery (TLM) is an emerging technique for the management of laryngeal and other head and neck malignancies. It is increasingly being used in place of traditional open surgery because of lower morbidity and improved organ preservation. Since the surgery is performed from the inside working outward as opposed to working from the outside in, there is less damage to the supporting structures that lie external to the tumor. Coupling the laser to a micromanipulator and a microscope allows precise tissue cutting and hemostasis; thereby improving visualization and precise ablation. The basic approach and principles of performing TLM, the devices currently in use, and the associated dosimetry parameters will be discussed. The benefits of using TLM over conventional surgery, common complications and the different settings used depending on the location of the tumor will also be discussed. Although the CO(2) laser is the most versatile and the best-suited laser for TLM applications, a variety of lasers and different parameters are used in the treatment of laryngeal cancer. Improved instrumentation has lead to an increased utilization of TLM by head and neck cancer surgeons and has resulted in improved outcomes. Laser energy levels and spot size are adjusted to vary the precision of cutting and amount of hemostasis obtained.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Rubinstein M,Armstrong WBdoi
10.1007/s10103-010-0834-5subject
Has Abstractpub_date
2011-01-01 00:00:00pages
113-24issue
1eissn
0268-8921issn
1435-604Xjournal_volume
26pub_type
杂志文章,评审abstract：:Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a side effect of bisphosphonate therapy. However, its pathophysiology is not yet fully elucidated, and effective treatment of BRONJ remains unclear. The aim of this study is to investigate the effects of alendronate on oral keratinocytes and of low-level laser...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1382-6
更新日期：2015-02-01 00:00:00
abstract：:Wound healing is a very complex process, some phases of which have only recently been explained. Magnetic and electromagnetic fields can modulate this process in a non-thermal way. The aim of this research was to compare the influence of constant and pulsed electromagnetic fields and low-level laser therapy (LLLT) on ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0564-0
更新日期：2009-05-01 00:00:00
abstract：:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2293-8
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:Acne scarring represents a common problem that negatively impacts patients' quality of life. Different types of treatments are currently available for this dermatological condition. This study evaluates the efficacy of a new 675-nm laser source system on acne scars with the use of established parameters that gu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03063-6
更新日期：2021-02-01 00:00:00
abstract：:The present study aims to identify (1) what proportion of abstracts of clinical trials presented at The American Society for Laser Medicine and Surgery (ASLMS) annual meetings are published as full reports, (2) time to publication, and (3) factors that may predict the publication of research in peer-reviewed journals....
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0484-4
更新日期：2008-07-01 00:00:00
abstract：:The published online version contains mistake. Warren S. Warren was not included in the author group section. Corrected author group section is shown above. ...
journal_title：Lasers in medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10103-017-2339-y
更新日期：2017-12-01 00:00:00
abstract：:Neuropathic pain (NP) is caused by damage to the nervous system due to reactive oxygen spices (ROS) increase, antioxidants reduction, ATP production imbalance, and induction of apoptosis. In this investigation, we applied low-level laser 660 nm (photobiomodulation therapy) as a new strategy to modulate pain. In order ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2062-0
更新日期：2016-12-01 00:00:00
abstract：:Skin represents an interface between internal and external environment; it protects human body by regulating the water loss and the maintenance of body temperature, defending against irritant and pathogen agents, and against physical, chemical, and UV damage. It provides to essential physiological functions, such as t...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2635-1
更新日期：2019-04-01 00:00:00
abstract：:A disrupted wound repair process often leads to the development of chronic wounds, and pose a major physical, social and economic inconvenience on patients and the public health sector. Chronic wounds are a common complication seen in diabetes mellitus (DM), and often the severity necessitates amputation of the lower ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03041-y
更新日期：2020-06-01 00:00:00
abstract：:This study aimed to evaluate in vitro performance of near-infrared laser transillumination (NIR-LTI) for detecting early occlusal caries in permanent teeth and compare it with quantitative light-induced fluorescence (QLF), DIAGNOdent Pen (DDPen), and conventional radiography (CR). Ninety-four occlusal surfaces present...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1704-3
更新日期：2015-09-01 00:00:00
abstract：:Low-level laser therapy (LLLT) is a form of photon therapy which can be a non-invasive therapeutic procedure in cancer therapy using low-intensity light in the range of 450-800 nm. One of the main functional features of laser therapy is the photobiostimulation effects of low-level lasers on various biological systems ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2049-x
更新日期：2016-12-01 00:00:00
abstract：:We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1851-1
更新日期：2016-02-01 00:00:00
abstract：:Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). Low-level laser therapy (LLLT) is thought to have an a...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-016-2114-5
更新日期：2017-02-01 00:00:00
abstract：:The aim of this in vitro study was to determine the effect of different remineralization agents and laser on caries resistance of primary enamel. In the study, 150 sound primary molars were used. The initial microhardness values were measured and the teeth were randomly assigned to ten treatment groups (n = 15): no tr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2667-6
更新日期：2019-07-01 00:00:00
abstract：:The purpose of this study is to evaluate microtensile bond strength (μTBS) of an etch-and-rinse adhesive to enamel and dentin after treatment with Er:YAG laser using different pulse durations. Extracted human molars were flattened to obtain enamel or dentin surfaces. The enamel specimens (E) were divided into nine gro...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0830-9
更新日期：2012-01-01 00:00:00
abstract：:Laser micromachining with ultrashort pulses has shown great promise for clean, safe surgical treatment of bone tissue. However, comparisons of performance and development of "best practice" have been hampered by the difficulty of comparing results across a wide variety of experimental approaches and under surgically i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02899-x
更新日期：2020-08-01 00:00:00
abstract：:The main goal of anti-cancer therapeutic approaches is to induce apoptosis in tumor masses but not in the normal tissues. Nevertheless, the combination of photodynamic irradiation with complementary oncostatic agents contributes to better therapeutic performance. Here, we applied two different cell lines; SKOV3 ovaria...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2016-6
更新日期：2016-11-01 00:00:00
abstract：:The laser source with 3 μm/2 μm output wavelength has many application prospects in clinical medicine, photoelectric countermeasure, and scientific research measurement. An Er3+ doped ZBLAN fiber laser with output wavelength of 2 .8 μm and 1 .6 μm is experimentally studied. By setting the pump power to 5 W, a continuo...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02766-9
更新日期：2019-10-01 00:00:00
abstract：:The current study evaluates whether the addition of low-level laser therapy into standard conventional physical therapy in elderly with bilateral symptomatic tri-compartmental knee arthritis can successfully postpone the need for joint replacement surgery. A prospective randomized cohort study of 100 consecutive unsel...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-015-1814-6
更新日期：2015-12-01 00:00:00
abstract：:The purpose of this study is to determine the effectiveness of endoscopic diode laser therapy in patients presenting rectal bleeding due to chronic radiation proctitis (CRP). A retrospective analysis of CRP patients who underwent diode laser therapy in a single institution between 2010 and 2016 was carried out. The pa...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2323-6
更新日期：2018-01-01 00:00:00
abstract：:Photodynamic rejuvenation therapy (PDRT) is a growing field in cosmetic dermatology. In this study, different sources of light (a yellow laser, a red laser and ultraviolet A (UVA) lamps) were used to activate a second-generation photosensitiser, hypericin. Uptake of hypericin was monitored over 24 h and efficacy of PD...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1115-2
更新日期：2013-02-01 00:00:00
abstract：:In the present study, we demonstrated the use of nanoporous zinc oxide (ZnO NPs) in photodynamic therapy. The ZnO NPs structure possesses a high surface to volume ratio due to its porosity and ZnO NPs can be used as an efficient photosensitizer carrier system. We were able to grow ZnO NPs on the tip of borosilicate gl...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0989-8
更新日期：2012-05-01 00:00:00
abstract：:Low-level visible light irradiation was found to stimulate proliferation potential of various types of cells in vitro. Stem cells in general are of significance for implantation in regenerative medicine. The aim of the present study was to investigate the effect of low-level light irradiation on the proliferation of m...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1207-z
更新日期：2013-07-01 00:00:00
abstract：:The use of the CO(2) laser in the management of oral dysplastic lesions has become a more common practice. Very few studies have evaluated recurrence, residual disease malignant transformation, and overall outcome in patients undergoing such a procedure. In this prospective study, a total of 123 oral dysplastic lesion...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-011-0916-z
更新日期：2012-01-01 00:00:00
abstract：:Antibiotics and photodynamic therapy (PDT) are widely employed in curing acne. However, antibiotics as an effective treatment would lead to bacterial resistance and severe side effects. In this study, we aimed to develop a novel TBO hydrogel, which could prolong the retention time of photosensitizer (TBO) at the lesio...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02727-2
更新日期：2019-10-01 00:00:00
abstract：:We observed the promoting effects of the 2940-nm erbium:YAG (Er:YAG) fractional laser in topical drug delivery for psoriasis. A total of five (four males and one female) recalcitrant psoriasis patients were given laser treatment eight times at 1-week intervals with the following parameters: 5-11% spot density and 100-...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-017-2259-x
更新日期：2017-08-01 00:00:00
abstract：:The molecular changes in gene expression following ablative laser treatment of skin lesions, such as atrophic scars and UV-damaged skin, are not completely understood. A standardized in vitro model of human skin, to study the effects of laser treatment on human skin, has been recently developed. Therefore, the aim of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2175-0
更新日期：2017-05-01 00:00:00
abstract：:Retinal development involves a complex coordination of events that may be affected by premature delivery, leading to retinopathy of prematurity (ROP), a potential blinding childhood disease. The avascular retina drives further disease progression, with laser ablation reducing unfavorable anatomic outcomes as well as m...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-011-1021-z
更新日期：2013-02-01 00:00:00
abstract：:Hyperhidrosis and bromhidrosis were lately reported as novel side effects of laser-assisted removal of axillary hair. The goal of our study was to evaluate the reversibility of these two side effects. An observational, single-center cohort study included over a 30-month screening period 30 patients with newly reported...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1404-4
更新日期：2014-03-01 00:00:00
abstract：:Low-level laser irradiation (LLLI) and recombinant human bone morphogenetic protein type 2 (rhBMP-2) have been used to stimulate bone formation. LLLI stimulates proliferation of osteoblast precursor cells and cell differentiation and rhBMP-2 recruits osteoprogenitor cells to the bone healing area. This in vivo study e...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1022-y
更新日期：2012-09-01 00:00:00
