Abstract：
:Previous in vivo and in vitro studies have reported that low-level diode laser therapy induces a biostimulatory effect, such as cell proliferation. The aim of the present study was to evaluate whether the laser irradiation of osteoblast-like cells (MG-63) can modify alkaline phosphatase activity (ALP), antigenic profile, and phagocytic capacity. The MG-63 cell line was exposed to diode laser (ezLase) of 940 nm at 1-1.5 W/cm(2) and 3-4 J. ALP was evaluated by a spectrophotometric technique and antigenic expression analysis (CD 54, CD80, CD86, HLA-DR), and phagocytic activity was analyzed by flow cytometry. At 24 h, the treated groups showed an increased ALP, and the highest increase versus controls (P = 0.002) was at the dose of 1 W/cm(2) and 3 J; this modulation of the antigenic profile translated into a reduced expression of CD54, CD86, and HLA-DR and a slightly decreased phagocytic capacity with respect to the nonirradiated control group at the different intensities and fluencies assayed. These results demonstrate that laser therapy can exert a biostimulatory effect on osteoblastic cells at different levels, which may be clinically useful in the regeneration of bone tissue.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Medina-Huertas R,Manzano-Moreno FJ,De Luna-Bertos E,Ramos-Torrecillas J,García-Martínez O,Ruiz Cdoi
10.1007/s10103-014-1557-9subject
Has Abstractpub_date
2014-07-01 00:00:00pages
1479-84issue
4eissn
0268-8921issn
1435-604Xjournal_volume
29pub_type
杂志文章abstract：:In this study we compared the microleakage of conventional glass ionomer cement (GIC) restorations following the use of different methods of root caries removal. In vitro root caries were induced in 75 human root dentin samples that were divided in five groups of 15 each according to the method used for caries removal...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0840-7
更新日期：2012-01-01 00:00:00
abstract：:The use of the CO(2) laser in the management of oral dysplastic lesions has become a more common practice. Very few studies have evaluated recurrence, residual disease malignant transformation, and overall outcome in patients undergoing such a procedure. In this prospective study, a total of 123 oral dysplastic lesion...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-011-0916-z
更新日期：2012-01-01 00:00:00
abstract：:The aim of this work was to investigate the long-term effects of a single application of a water-cooled pulsed neodymium yttrium aluminium garnet (Nd:YAG) laser, in combination with scaling and root planing (SRP) for the treatment of periodontal inflammation. Twenty-two patients were included in this split-mouth singl...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-010-0807-8
更新日期：2011-11-01 00:00:00
abstract：:The main goal of anti-cancer therapeutic approaches is to induce apoptosis in tumor masses but not in the normal tissues. Nevertheless, the combination of photodynamic irradiation with complementary oncostatic agents contributes to better therapeutic performance. Here, we applied two different cell lines; SKOV3 ovaria...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2016-6
更新日期：2016-11-01 00:00:00
abstract：:Hyperhidrosis and bromhidrosis were lately reported as novel side effects of laser-assisted removal of axillary hair. The goal of our study was to evaluate the reversibility of these two side effects. An observational, single-center cohort study included over a 30-month screening period 30 patients with newly reported...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1404-4
更新日期：2014-03-01 00:00:00
abstract：:Acute lung injury (ALI) is defined as respiratory failure syndrome, in which the pathogenesis could occur from sepsis making it a life-threatening disease by uncontrolled hyperinflammatory responses. A possible treatment for ALI is the use of low-power infrared lasers (LPIL), whose therapeutical effects depend on wave...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2656-9
更新日期：2019-02-01 00:00:00
abstract：:The aim of this study was to evaluate the efficacy of low-level laser therapy (LLLT) and alpha-lipoic acid (ALA) in the treatment of burning mouth syndrome (BMS) and secondary oral burning (SOB) by unstimulated sialometry, symptom assessment, and measurement of salivary TNF-α levels. Forty-four patients were randomize...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2472-2
更新日期：2018-08-01 00:00:00
abstract：:In root canal therapy, irrigating solutions are essential to assist in debridement and disinfection. Their spread and action is often restricted by canal anatomy, requiring some form of activation. Lasers have been shown to be promising tools for this purpose (laser-activated irrigation (LAI)). For LAI to be effective...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1307-4
更新日期：2014-09-01 00:00:00
abstract：:Papacarie Duo™ is clinically used and has proven effectiveness; however, it is necessary to improve its antimicrobial action. The combined treatment of Papacarie Duo™ with Urucum (Bixa Orellana) could create a potential tool for dental caries treatment; its extract obtained from the seeds' pericarp contains a water-so...
journal_title：Lasers in medical science
pub_type： 信件
doi：10.1007/s10103-019-02857-7
更新日期：2020-04-01 00:00:00
abstract：:To identify the best low level laser photobiomodulation application site at the same irradiation time to increase the viability of the skin flap in rats. Eighteen male rats (Rattus norvegicus: var. Albinus, Rodentia Mammalia) were randomly distributed into three groups (n = 6). Group I (GI) was submitted to simulated ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2694-3
更新日期：2019-07-01 00:00:00
abstract：:The aim of this study was to evaluate the bactericidal effect of ultraviolet (UV) light at 265-nm (UVC) and 310-nm (UVB) wavelengths from a newly developed UV light-emitting diode (LED) device against cariogenic bacteria in vitro. Suspensions of Streptococcus mutans (S. mutans) and Streptococcus sobrinus were directly...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2685-4
更新日期：2019-07-01 00:00:00
abstract：:Antimicrobial photodynamic therapy (APDT) combined with endodontic treatment has been recognized as an alternative approach to complement conventional root canal disinfection methods on bacterial biofilms. We developed an in vitro model of bioluminescent Candida albicans biofilm inside curved dental root canals and i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1629-x
更新日期：2015-08-01 00:00:00
abstract：:Striae gravidarum is a common dermatologic condition for females caused by multiple factors during pregnancy. It remains a therapeutic challenge especially in the striae alba (SA) stage, generating psychological and emotional distress to those affected. This study aims to compare the efficacy and safety of 1565-nm non...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03203-y
更新日期：2021-01-07 00:00:00
abstract：:Although the application of Q-switched lasers on nevus of Ota (OTA) is well demonstrated, debates about clinical option between Q-switched alexandrite laser (QSA) and Q-switched Nd:YAG laser (QSNY) still remain. This systematic review and meta-analysis estimated the overall successful rate of OTA pigment clearance and...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10103-016-1885-z
更新日期：2016-04-01 00:00:00
abstract：:Oral mucositis (OM) and radiodermatitis (RD) are serious side effects of radiotherapy (RT), often leading to its suspension, need for analgesics, and enteral/parenteral nutrition. Laser therapy is becoming a recommended treatment option. This prospective study aimed at demonstrating the beneficial effect of class IV l...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1857-8
更新日期：2016-04-01 00:00:00
abstract：:The effects of He-Ne laser irradiation on erythrocyte hemolysis were studied. Erythrocytes are prone to be easily damaged with hemolysis under laser irradiation. It was found that the power density (PD) of laser irradiation, but not the total irradiation power, is the crucial parameter for the hemolysis. Under irradia...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0320-z
更新日期：2004-01-01 00:00:00
abstract：:The optical properties of the skin (absorption coefficient, scattering coefficient, refractive index) may serve to characterize the skin and are important for correct light dosimetry in many optical diagnostic procedures and laser treatments especially photodynamic therapy and laser therapy. We determined in vivo the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-009-0725-9
更新日期：2010-03-01 00:00:00
abstract：:Laser acupuncture is a modality of low-level light therapy used as an alternative to needling for the past three decades. Although it has proved effective for the treatment of various conditions, the mechanisms underlying its effects are not fully understood. To contribute to this understanding, this study was designe...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1260-7
更新日期：2013-09-01 00:00:00
abstract：:This study aimed to investigate the influence of low-power 830 nm gallium-aluminium-arsenide (GaAlAs) laser [continuous wave (CW) 40 mW and fluence 4 J/cm(2), with total energy density of 16 J/cm(2)] on the healing of human infra-bony defects treated with bioactive glass graft material. Twenty patients with chronic pe...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-008-0576-9
更新日期：2009-05-01 00:00:00
abstract：:The aim of this study is to analyze the effect of agitation of ethylenediaminetetraacetic acid (EDTA) with diode laser at different agitation times on root dentin microhardness. Eighty-four specimens were divided randomly into seven groups, as follows: (1) distilled water, (2) 17% EDTA, (3) EDTA with 60 s ultrasonic a...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1364-8
更新日期：2015-02-01 00:00:00
abstract：:In this study, shear bond strength (SBS) of metal orthodontic brackets to porcelain following conditioning by Er:YAG (erbium-doped yttrium aluminum garnet) and Nd:YAG (neodymium-doped yttrium aluminum garnet) laser in comparison to conventional methods was evaluated. One hundred glazed porcelain discs with an upper ce...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0878-6
更新日期：2012-03-01 00:00:00
abstract：:The aim of this study was to verify the maximum number of repetitions, fatigue index, blood lactate concentration ([Lac]), and cardiac autonomic responses after LED irradiation (LEDI) in the ipsilateral and contralateral limb. Twelve male subjects (22.0 ± 3.86 years; weight 82.94 ± 12.58 kg; height 1.77 ± 0.05 m), phy...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-017-2391-7
更新日期：2018-02-01 00:00:00
abstract：:Skin represents an interface between internal and external environment; it protects human body by regulating the water loss and the maintenance of body temperature, defending against irritant and pathogen agents, and against physical, chemical, and UV damage. It provides to essential physiological functions, such as t...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2635-1
更新日期：2019-04-01 00:00:00
abstract：:Photodynamic therapy (PDT) with photosensitizer is one of the promising modalities for cancer treatment. For clinical use of PDT, screening process should be preceded to enhance sensitivity to PDT. Thus, we investigated a molecular biomarker to determine the sensitivity to pheophorbide a (Pa)-PDT in immortalized human...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1350-1
更新日期：2015-02-01 00:00:00
abstract：:Bothropic venom contains a range of biologically active substances capable of causing severe local and systemic envenoming symptomatology within its victims. The snake anti-venom is effective against systemic effects but has no neutralizing effect against the fast developing local effects. Herein, mice gastrocnemius i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2252-4
更新日期：2017-08-01 00:00:00
abstract：:Minimal hepatic encephalopathy (MHE) has been shown to affect daily functioning, quality of life, driving and overall mortality. However, little is known about treating or diagnosing early impairments involved in MHE. We studied one of its precipitating factors, portal hypertension. The purpose was to evaluate an enha...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2042-4
更新日期：2016-11-01 00:00:00
abstract：:The aim of the present study was to investigate the influence of low-level red (660 nm) and infrared (780 nm) laser with four different radiance exposures on human umbilical vein endothelial cells (HUVECs) in vitro. HUVECs (1.5 × 104) were incubated in 96-well culture plates. The cells were maintained in M199 medium s...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03016-z
更新日期：2021-02-01 00:00:00
abstract：:Laser micromachining with ultrashort pulses has shown great promise for clean, safe surgical treatment of bone tissue. However, comparisons of performance and development of "best practice" have been hampered by the difficulty of comparing results across a wide variety of experimental approaches and under surgically i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02899-x
更新日期：2020-08-01 00:00:00
abstract：:Although ear reconstruction technology has been highly developed in recent years, hair growth on the reconstructed ear has plagued both surgeons and patients. In this paper, the authors introduce a clinical application of intense pulsed light depilation in total auricular reconstruction. From August 2012 to August 201...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-017-2255-1
更新日期：2017-08-01 00:00:00
abstract：:Infrared laser therapy is used for skeletal muscle repair based on its biostimulative effect on satellite cells. However, shortening of telomere length limits regenerative potential in satellite cells, which occurs after each cell division cycle. Also, laser therapy could be more effective on non-physiologic tissues. ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1956-1
更新日期：2016-08-01 00:00:00
