Abstract：
:The PHQ-9 has been found to be reliable and valid, but with both a single and two-factor structure suggested in the literature. This measure has not yet been subject to psychometric investigation using Mokken scale analysis. Confirmatory Factor Analysis (CFA) and Mokken analysis were performed on retrospective data from an NHS Trust. CFA found a two-factor structure was a significantly better fit; however, the factors were highly correlated. Mokken analysis suggested that a single scale was viable. The findings support recent research by Gonzalez-Blanch et al. (2018) in suggesting a one factor model is most appropriate for the PHQ-9.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Boothroyd L,Dagnan D,Muncer Sdoi
10.1016/j.psychres.2018.12.048subject
Has Abstractpub_date
2019-01-01 00:00:00pages
532-534eissn
0165-1781issn
1872-7123pii
S0165-1781(18)30761-3journal_volume
271pub_type
杂志文章abstract：:Previous studies framed a possible link of retinoic acid (RA) regulation in brain to autism spectrum disorders (ASD) etiology. The aim of this study was to measure serum levels of RA in relation to the degree of the severity of autism. Serum RA levels were measured by enzyme-linked immunosorbent assay (ELISA) colorime...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.08.091
更新日期：2018-11-01 00:00:00
abstract：:Compared rehospitalization rates in patients with schizophrenia or bipolar I disorder to patients with major depressive disorder remains unclear. This study aimed to compare the time to rehospitalization of the three groups. Other clinical variables were also examined. Rehospitalization status was monitored for all ad...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2009.12.003
更新日期：2010-12-30 00:00:00
abstract：:The reliability and validity of the Toronto Structured Interview for Alexithymia (TSIA) have been demonstrated in previous studies with English-speaking community and psychiatric samples and a German-speaking psychiatric sample. The aim of this study was to evaluate the psychometric properties of the TSIA in a mixed c...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.02.015
更新日期：2011-05-30 00:00:00
abstract：:As a well-known bile acid receptor, the role of Farnesoid X receptor (FXR) in the digestive system and cardiovascular system has been widely explored. However, there are very few studies involving FXR in the central nervous system. In this study, we explored the role of FXR in the pathogenesis of depression, a serious...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.025
更新日期：2018-06-01 00:00:00
abstract：:Stress results in a variety of neuroendocrine, immune and behavioral responses and represents a risk factor for many disorders. Following exposure to stress, glucocorticoids are secreted from the adrenal cortex and act via the ligand-activated glucocorticoid receptor (GR). Several polymorphisms of the GR-encoding gene...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.10.001
更新日期：2016-12-30 00:00:00
abstract：:High rates of psychiatric impairment in adults with 22q11 deletion syndrome (22q11DS, also referred to as DiGeorge or velocardiofacial syndrome) suggest that behavioral trajectories of children with 22q11DS may provide critical etiologic insights. Past findings that report Diagnostic and Statistical Manual (DSM) diagn...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.03.023
更新日期：2009-03-31 00:00:00
abstract：:We examined the relationship between the cortisol response to stress and aggression in patients with attention deficit hyperactivity disorder (ADHD). Based on a report stating that only some of the patients with ADHD retain their hypothalamic-pituitary-adrenal axis reactivity to stress, we separately analyzed the rela...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.04.001
更新日期：2007-09-30 00:00:00
abstract：:We investigated the serotonin transporter gene (5-HTTLPR) in the functioning of euthymic patients with mood disorders (n=285) and healthy controls (n=94). The 5-HTTLPR genotype showed marginal associations with working, familial and social adjustment, with marked differences between controls and patients. Because of t...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2005.01.006
更新日期：2005-04-15 00:00:00
abstract：:The Center for Epidemiologic Studies Depression Scale (CES-D) has been used extensively in community-based surveys to describe and explain the prevalence of depression in the general population. Yet, questions have been raised regarding its adequacy for use among ethnic minority because of its factor variance. Employi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.06.022
更新日期：2010-08-30 00:00:00
abstract：:A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(86)90052-1
更新日期：1986-03-01 00:00:00
abstract：:The phenotypic heterogeneity of Autism Spectrum Disorders (ASD) presents particular research challenges in the assessment of symptom severity, while the standardized Autism Diagnostic Observation Schedule (ADOS) scores present a severity metric, namely calibrated severity scores (CSS) that are relatively impervious to...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.12.084
更新日期：2018-03-01 00:00:00
abstract：:Depressive mixed state (DMS) (a major depressive episode [MDE] with some concurrent hypomanic symptoms) is understudied. The aims of the study were to find if the prevalence of DMS, and its clinical correlates, in bipolar II depressed outpatients changed according to bipolar II age at onset. A consecutive sample of 92...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(01)00258-x
更新日期：2001-09-20 00:00:00
abstract：:Executive functions play an important role in problem-solving and self-control. Set-shifting is an aspect of executive functioning and represents cognitive flexibility. The inability to control eating in Binge Eating Disorder (BED) may imply deficits in set-shifting which could be exacerbated by negative mood and depr...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.psychres.2015.09.001
更新日期：2015-12-15 00:00:00
abstract：:It has been suggested that low frequency transcranial magnetic stimulation (TMS) over left temporo-parietal cortex may reduce the frequency and intensity of auditory hallucinations in schizophrenia. Sixteen patients with hallucinations, treatment-resistant for at least 2 months, were randomised into a placebo-controll...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.psychres.2004.03.005
更新日期：2004-06-30 00:00:00
abstract：:The dopamine hypothesis of schizophrenia received strong support when a two- to three-fold elevation of D2 receptor densities was demonstrated by positron emission tomography (PET) and [11C]N-methylspiperone ([11C]NMSP). In the present study, the reproducibility of this finding was examined by application of a similar...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(95)02732-d
更新日期：1995-08-08 00:00:00
abstract：:Recent studies have reported that patients with unipolar major depression may show a lower whole brain cerebral blood flow (CBF) and reduced regional CBF in frontal, temporal, and parietal lobes. The present study used single photon emission computed tomography (SPECT) with the CBF marker Tc-99m-hexamethylpropyleneami...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(93)90012-7
更新日期：1993-06-01 00:00:00
abstract：:The mineralocorticoid receptor (Nr3c2) has received increased attention as an important stress-related gene. Here, we sought to uncover candidate genes regulating the expression of Nr3c2. Using a genetical genomics approach, we identified a significant trans-regulated expression quantitative trait locus (eQTL) at Chro...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.112760
更新日期：2020-01-07 00:00:00
abstract：:The investigation of comorbidity between major depressive disorder (MDD) and personality disorders (PDs) has attracted considerable interest. Whereas some studies found that the presence of PDs has adverse effects on the course and treatment of MDD, others have failed to demonstrate this link. These inconsistent findi...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/j.psychres.2007.06.014
更新日期：2008-08-15 00:00:00
abstract：:The aim of this study was to investigate theory of mind (ToM) in a sample of depressed patients with mild symptom severity using a measure with varied cognitive processing demands. Patients demonstrated impaired performance on second-order, cognitively demanding ToM scenarios. Reduced ToM ability was associated with p...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.06.018
更新日期：2013-12-15 00:00:00
abstract：:Suicide is one of the most common causes of death in adolescents. This study identified trends in the prevalence of and factors influencing suicidal ideation and attempts among Korean adolescents. Data were drawn from the third through the thirteenth (2007-2017) annual Korean Youth Risk Behavior Web-based Surveys. Par...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113228
更新日期：2020-09-01 00:00:00
abstract：:Pharmacological treatments for alcohol use disorder show a modest effect, and they are unavailable in certain countries. The study's aim is to investigate the effects of gabapentin on alcohol drinking. One hundred twelve Thai individuals with alcohol dependence and very high alcohol consumption were randomly assigned ...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2018.09.002
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Declarative memory disturbances, known to substantially contribute to cognitive impairment in schizophrenia, have previously been attributed to prefrontal as well as hippocampal dysfunction. AIMS:To characterize the role of prefrontal and mesolimbic/hippocampal dysfunction during memory encoding in schizoph...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2010.03.007
更新日期：2010-09-30 00:00:00
abstract：:The purpose of this research was to examine the relationship between sensation seeking and online poker gambling in a community sample of adult online poker players, when controlling for age, gender, anxiety and depression. In total, 288 online poker gamblers were recruited. Sociodemographic data, gambling behavior (C...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.03.024
更新日期：2018-06-01 00:00:00
abstract：:This study assessed the subjective and cardiovascular effects of relevant doses of cocaine administration during steady-state treatment of the combination of amantadine and baclofen compared to placebo. Participants included 8 healthy, male, cocaine-dependent, non-treatment-seeking individuals (age=36.6+/-5.9; 75% Afr...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.03.012
更新日期：2007-08-30 00:00:00
abstract：:Despite the widespread abuse of marijuana, knowledge about its effects in the human brain is limited. Brain glucose metabolism with and without delta 9 tetrahydrocannabinol (THC) (main psychoactive component of marijuana) was evaluated in eight normal subjects and eight chronic marijuana abusers with positron emission...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(96)02817-x
更新日期：1996-05-31 00:00:00
abstract：:There is increasing evidence to suggest both a symptomatic overlap and a clinically significant degree of co-occurrence between Autism Spectrum Disorders (ASD) and psychotic disorders such as schizophrenia but the nature of such relationships remain unclear. We reviewed the literature reporting prevalence rates of Aut...
journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2017.01.017
更新日期：2017-04-01 00:00:00
abstract：:High variability in adaptive behavior in cognitively-able adults with autism spectrum disorder has been previously reported, and may be caused by the high prevalence of psychiatric comorbidity in this population. This study's goals were to examine self-reported psychiatric symptoms in students with ASD, and to identif...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.01.098
更新日期：2019-03-01 00:00:00
abstract：:Early response to antipsychotic medication has been shown to accurately predict later response to continued use of the same treatment in patients with chronic schizophrenia. This study examines whether this predictive pattern exists for patients with first-episode psychosis. We used a data-driven threshold for early r...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.psychres.2010.11.017
更新日期：2011-05-15 00:00:00
abstract：:Patients with affective disorders frequently report problems with attention, concentration and memory, although little research has investigated subjective cognitive complaints relative to objective neuropsychological deficits. We compared subjective (self-rated) cognition and objective (clinician-rated) neuropsycholo...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2004.12.009
更新日期：2005-07-15 00:00:00
abstract：:Trait anxiety, a personality dimension, has been characterized by functional consequences such as increased distractibility, attentional bias in favor of threat-related information and hyper-responsive amygdala. However, literature on the association between resting state brain functional connectivity, as studied usin...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2015.07.006
更新日期：2015-10-30 00:00:00
