当前位置： SCI文献检索 > Cell Host & Microbe期刊下所有文献 > Bacterial persistence: finding the "sweet spot".

Bacterial persistence: finding the "sweet spot".

Abstract：

:Studies described by Eisele et al. (2013) and Xavier et al. (2013) in this issue of Cell Host & Microbe show that the bacterial pathogens Salmonella and Brucella exploit the increased levels of glucose present in alternatively activated macrophages to sustain chronic infections in experimentally infected mice.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Roop RM 2nd,Caswell CC

doi

10.1016/j.chom.2013.07.016

subject

Has Abstract

pub_date

2013-08-14 00:00:00

pages

119-20

issue

2

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(13)00264-3

journal_volume

14

pub_type

评论,杂志文章

相关文献

Cell Host & Microbe文献大全
  • The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages.

    abstract：:The ecological dynamics underlying the coexistence between antagonistic populations of bacteria and their viruses, bacteriophages (phages), in the mammalian gut microbiota remain poorly understood. We challenged a murine synthetic bacterial community with phages to study the factors allowing phages-bacteria coexistenc...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.06.002

    authors： Lourenço M,Chaffringeon L,Lamy-Besnier Q,Pédron T,Campagne P,Eberl C,Bérard M,Stecher B,Debarbieux L,De Sordi L

    更新日期：2020-09-09 00:00:00

  • Bacteroides in the infant gut consume milk oligosaccharides via mucus-utilization pathways.

    abstract：:Newborns are colonized with an intestinal microbiota shortly after birth, but the factors governing the retention and abundance of specific microbial lineages are unknown. Nursing infants consume human milk oligosaccharides (HMOs) that pass undigested to the distal gut, where they may be digested by microbes. We deter...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2011.10.007

    authors： Marcobal A,Barboza M,Sonnenburg ED,Pudlo N,Martens EC,Desai P,Lebrilla CB,Weimer BC,Mills DA,German JB,Sonnenburg JL

    更新日期：2011-11-17 00:00:00

  • Carving a Niche for Antibacterial α-Defensins when Craving.

    abstract：:In this issue of Cell Host & Microbe, Liang et al. (2019) show that α-defensins in the gastrointestinal tract sustain defenses to enteric pathogens during starvation. mTOR-dependent sensing of nutrient loss promotes production of an α-defensin regulator, which sustains α-defensin levels, loss of which increases lethal...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2019.04.009

    authors： Foerster EG,Girardin SE

    更新日期：2019-05-08 00:00:00

  • KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses.

    abstract：:Human type A Enteroviruses (EV-As) cause diseases ranging from hand-foot-and-mouth disease to poliomyelitis-like disease. Although cellular receptors are identified for some EV-As, they remain elusive for the majority of EV-As. We identify the cell surface molecule KREMEN1 as an entry receptor for coxsackievirus A10 (...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2018.03.019

    authors： Staring J,van den Hengel LG,Raaben M,Blomen VA,Carette JE,Brummelkamp TR

    更新日期：2018-05-09 00:00:00

  • Networking at the level of host immunity: immune cell interactions during persistent viral infections.

    abstract：:Persistent viral infections are the result of a series of connected events that culminate in diminished immunity and the inability to eliminate infection. By building our understanding of how distinct components of the immune system function both individually and collectively in productive versus abortive responses, n...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2013.05.014

    authors： Ng CT,Snell LM,Brooks DG,Oldstone MB

    更新日期：2013-06-12 00:00:00

  • Leishmania evades host immunity by inhibiting antigen cross-presentation through direct cleavage of the SNARE VAMP8.

    abstract：:During phagocytosis, microorganisms are taken up by immune cells into phagosomes. Through membrane-trafficking events mediated by SNARE proteins, phagosomes fuse with lysosomes, generating degradative phagolysosomes. Phagolysosomes contribute to host immunity by linking microbial killing within these organelles with a...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2013.06.003

    authors： Matheoud D,Moradin N,Bellemare-Pelletier A,Shio MT,Hong WJ,Olivier M,Gagnon E,Desjardins M,Descoteaux A

    更新日期：2013-07-17 00:00:00

  • Automated Prediction and Annotation of Small Open Reading Frames in Microbial Genomes.

    abstract：:Small open reading frames (smORFs) and their encoded microproteins play central roles in microbes. However, there is a vast unexplored space of smORFs within human-associated microbes. A recent bioinformatic analysis used evolutionary conservation signals to enhance prediction of small protein families. To facilitate ...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.11.002

    authors： Durrant MG,Bhatt AS

    更新日期：2021-01-13 00:00:00

  • Sweet Talk: Regulating Glucose Metabolism in Toxoplasma.

    abstract：:Toxoplasma gondii, the causative agent of toxoplasmosis, is an intracellular parasite that demonstrates a remarkable ability to adapt to nutrient availability. In this issue of Cell Host & Microbe, Blume et al. (2015) describe the unique role of a gluconeogenic enzyme in regulation of glucose catabolism in T. gondii. ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2015.07.012

    authors： Guggisberg AM,Odom AR

    更新日期：2015-08-12 00:00:00

  • Reciprocal inhibition between intracellular antiviral signaling and the RNAi machinery in mammalian cells.

    abstract：:RNA interference (RNAi) is an established antiviral defense mechanism in plants and invertebrates. Whether RNAi serves a similar function in mammalian cells remains unresolved. We find that in some cell types, mammalian RNAi activity is reduced shortly after viral infection via poly-ADP-ribosylation of the RNA-induced...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2013.09.002

    authors： Seo GJ,Kincaid RP,Phanaksri T,Burke JM,Pare JM,Cox JE,Hsiang TY,Krug RM,Sullivan CS

    更新日期：2013-10-16 00:00:00

  • A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent.

    abstract：:The Lyme disease agent Borrelia burgdorferi is primarily transmitted to vertebrates by Ixodes ticks. The classical and alternative complement pathways are important in Borrelia eradication by the vertebrate host. We recently identified a tick salivary protein, designated P8, which reduced complement-mediated killing o...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2011.06.010

    authors： Schuijt TJ,Coumou J,Narasimhan S,Dai J,Deponte K,Wouters D,Brouwer M,Oei A,Roelofs JJ,van Dam AP,van der Poll T,Van't Veer C,Hovius JW,Fikrig E

    更新日期：2011-08-18 00:00:00

  • NMD: nonsense-mediated defense.

    abstract：:Initially described as an RNA surveillance pathway, nonsense-mediated decay (NMD) is also recognized to function in the regulation of host gene expression. In this issue of Cell Host & Microbe, three studies describe NMD-mediated defense strategies of plants and mammalian cells in response to pathogen infection. ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2014.08.015

    authors： Wachter A,Hartmann L

    更新日期：2014-09-10 00:00:00

  • Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.

    abstract：:The prototypic arenavirus lymphocytic choriomeningitis virus (LCMV), which naturally persists in rodents, represents a model for HIV, HBV, and HCV. Cleavage of the viral glycoprotein precursor by membrane-bound transcription factor peptidase, site 1 (Mbtps1 or site-1 protease), is crucial for the life cycle of arenavi...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2011.02.006

    authors： Popkin DL,Teijaro JR,Sullivan BM,Urata S,Rutschmann S,de la Torre JC,Kunz S,Beutler B,Oldstone M

    更新日期：2011-03-17 00:00:00

  • A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection.

    abstract：:Polymorphisms in the essential autophagy gene Atg16L1 have been linked with susceptibility to Crohn's disease, a major type of inflammatory bowel disease (IBD). Although the inability to control intestinal bacteria is thought to underlie IBD, the role of Atg16L1 during extracellular intestinal bacterial infections has...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2013.07.013

    authors： Marchiando AM,Ramanan D,Ding Y,Gomez LE,Hubbard-Lucey VM,Maurer K,Wang C,Ziel JW,van Rooijen N,Nuñez G,Finlay BB,Mysorekar IU,Cadwell K

    更新日期：2013-08-14 00:00:00

  • Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity.

    abstract：:Periodontitis is a common disease that is characterized by resorption of the alveolar bone and mediated by commensal bacteria that trigger host immune responses and bone destruction through unidentified mechanisms. We report that Nod1, an innate intracellular host receptor for bacterial peptidoglycan-related molecules...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2013.04.005

    authors： Jiao Y,Darzi Y,Tawaratsumida K,Marchesan JT,Hasegawa M,Moon H,Chen GY,Núñez G,Giannobile WV,Raes J,Inohara N

    更新日期：2013-05-15 00:00:00

  • Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes.

    abstract：:Salmonella Typhimurium causes diarrhea by infecting the epithelium and lamina propria of the intestinal mucosa and by secreting various effector proteins through type III secretion systems (TTSSs). However, the mechanisms by which Salmonella transverses the epithelium and is subsequently released into the lamina propr...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2011.11.013

    authors： Müller AJ,Kaiser P,Dittmar KE,Weber TC,Haueter S,Endt K,Songhet P,Zellweger C,Kremer M,Fehling HJ,Hardt WD

    更新日期：2012-01-19 00:00:00

  • ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

    abstract：:The Cullin-RING E3 ligase (CRL) family is commonly hijacked by pathogens to redirect the host ubiquitin proteasome machinery to specific targets. During HIV infection, CRL5 is hijacked by HIV Vif to target viral restriction factors of the APOBEC3 family for ubiquitination and degradation. Here, using a quantitative pr...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2019.05.008

    authors： Hüttenhain R,Xu J,Burton LA,Gordon DE,Hultquist JF,Johnson JR,Satkamp L,Hiatt J,Rhee DY,Baek K,Crosby DC,Frankel AD,Marson A,Harper JW,Alpi AF,Schulman BA,Gross JD,Krogan NJ

    更新日期：2019-07-10 00:00:00

  • The enteropathogenic E. coli effector EspB facilitates microvillus effacing and antiphagocytosis by inhibiting myosin function.

    abstract：:Enteropathogenic Escherichia coli (EPEC) destroys intestinal microvilli and suppresses phagocytosis by injecting effectors into infected cells through a type III secretion system (TTSS). EspB, a component of the TTSS, is also injected into the cytoplasm of host cells. However, the physiological functions of EspB withi...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2007.09.012

    authors： Iizumi Y,Sagara H,Kabe Y,Azuma M,Kume K,Ogawa M,Nagai T,Gillespie PG,Sasakawa C,Handa H

    更新日期：2007-12-13 00:00:00

  • Neutrophils Cause an Intravascular Traffic Jam.

    abstract：:Neutrophil swarming is defined by large numbers of cells simultaneously and rapidly migrating to a site of injury or infection. In this issue of Cell Host & Microbe, Lee et al. (2018) demonstrate that intravascular swarming of neutrophils occurs in response to Candida albicans infection and causes vascular occlusion a...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2017.12.011

    authors： Minns MS,Pearlman E

    更新日期：2018-01-10 00:00:00

  • Establishing Causality: Opportunities of Synthetic Communities for Plant Microbiome Research.

    abstract：:Plant microbiome research highlights the importance of indigenous microbial communities for host phenotypes such as growth and health. It aims to discover the molecular basis by which host-microbe and microbe-microbe interactions shape and maintain microbial communities and to understand the role of individual microor...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2017.07.004

    authors： Vorholt JA,Vogel C,Carlström CI,Müller DB

    更新日期：2017-08-09 00:00:00

  • The cancer microbiome atlas: a pan-cancer comparative analysis to distinguish tissue-resident microbiota from contaminants.

    abstract：:Studying the microbial composition of internal organs and their associations with disease remains challenging due to the difficulty of acquiring clinical biopsies. We designed a statistical model to analyze the prevalence of species across sample types from The Cancer Genome Atlas (TCGA), revealing that species equipr...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.12.001

    authors： Dohlman AB,Arguijo Mendoza D,Ding S,Gao M,Dressman H,Iliev ID,Lipkin SM,Shen X

    更新日期：2020-12-21 00:00:00

  • The relationship of the oral microbiotia to periodontal health and disease.

    abstract：:The oral microbial community represents the best-characterized consortium associated with the human host. There are strong correlations between the qualitative composition of the oral microbiota and clinically healthy or diseased states. However, additional studies are needed to elucidate the mechanisms that define th...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2011.09.008

    authors： Curtis MA,Zenobia C,Darveau RP

    更新日期：2011-10-20 00:00:00

  • Enteric infection and inflammation alter gut microbial ecology.

    abstract：:The complex microbial community residing within the intestine plays important roles in host defense. However, the impact of enteric infection and inflammation on this resident community has not been fully explored. In this issue of Cell Host & Microbe, Lupp and coworkers reveal that the composition of the intestinal m...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2007.07.006

    authors： Rawls JF

    更新日期：2007-08-16 00:00:00

  • A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation.

    abstract：:RIG-I detects double-stranded RNA (dsRNA) to trigger antiviral cytokine production. Protein deamidation is emerging as a post-translational modification that chiefly regulates protein function. We report here that UL37 of herpes simplex virus 1 (HSV-1) is a protein deamidase that targets RIG-I to block RNA-induced act...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2016.10.011

    authors： Zhao J,Zeng Y,Xu S,Chen J,Shen G,Yu C,Knipe D,Yuan W,Peng J,Xu W,Zhang C,Xia Z,Feng P

    更新日期：2016-12-14 00:00:00

  • Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection.

    abstract：:Pathogenic H7N9 avian influenza viruses continue to represent a public health concern, and several candidate vaccines are currently being developed. It is vital to assess if protective antibodies are induced following vaccination and to characterize the diversity of epitopes targeted. Here we characterized the binding...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2016.05.014

    authors： Henry Dunand CJ,Leon PE,Huang M,Choi A,Chromikova V,Ho IY,Tan GS,Cruz J,Hirsh A,Zheng NY,Mullarkey CE,Ennis FA,Terajima M,Treanor JJ,Topham DJ,Subbarao K,Palese P,Krammer F,Wilson PC

    更新日期：2016-06-08 00:00:00

  • Phosphorylation-Regulated Activation of the Arabidopsis RRS1-R/RPS4 Immune Receptor Complex Reveals Two Distinct Effector Recognition Mechanisms.

    abstract：:The Arabidopsis immune receptors RPS4 and RRS1 interact to co-confer responsiveness to bacterial effectors. The RRS1-R allele, with RPS4, responds to AvrRps4 and PopP2, whereas RRS1-S responds only to AvrRps4. Here, we show that the C terminus of RRS1-R but not RRS1-S is phosphorylated. Phosphorylation at Thr1214 in t...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.03.008

    authors： Guo H,Ahn HK,Sklenar J,Huang J,Ma Y,Ding P,Menke FLH,Jones JDG

    更新日期：2020-05-13 00:00:00

  • Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection.

    abstract：:Anti-helminth immunity involves CD4+ T cells, yet the precise effector mechanisms responsible for parasite killing or expulsion remain elusive. We now report an essential role for antibodies in mediating immunity against the enteric helminth Heligmosomoides polygyrus (Hp), a natural murine parasite that establishes ch...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2008.08.014

    authors： McCoy KD,Stoel M,Stettler R,Merky P,Fink K,Senn BM,Schaer C,Massacand J,Odermatt B,Oettgen HC,Zinkernagel RM,Bos NA,Hengartner H,Macpherson AJ,Harris NL

    更新日期：2008-10-16 00:00:00

  • Dyeing to learn more about the gut microbiota.

    abstract：:The switch from culture-based enumeration to deep sequencing has enabled microbial community composition to be profiled en masse. In a new article, Maurice et al. (2013) report the use of fluorescence-activated cell sorting (FACS) to perform a high-throughput analysis of gut microbiota community function. ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2013.01.011

    authors： Donia MS,Fischbach MA

    更新日期：2013-02-13 00:00:00

  • Epithelium, tear down this wall!

    abstract：:The presence of bacteria within epithelial-lined compartments, such as the lung, elicits rapid recruitment of innate immune cells. In this issue of Cell Host & Microbe, Chun and Prince (2009) report that epithelial cells facilitate this process by reorganizing their intercellular junctions to enhance immune cell trans...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2008.12.008

    authors： Nalle SC,Turner JR

    更新日期：2009-01-22 00:00:00

  • Serine phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori.

    abstract：:Cell migration and invasion require the coordinated regulation of cytoskeletal architectural changes by signaling factors, including the actin-binding protein cortactin. Bacterial and viral pathogens subvert these signaling factors to promote their uptake, spread and dissemination. We show that the gastric pathogen He...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2011.05.007

    authors： Tegtmeyer N,Wittelsberger R,Hartig R,Wessler S,Martinez-Quiles N,Backert S

    更新日期：2011-06-16 00:00:00

  • Host metabolism regulates intracellular growth of Trypanosoma cruzi.

    abstract：:Metabolic coupling of intracellular pathogens with host cells is essential for successful colonization of the host. Establishment of intracellular infection by the protozoan Trypanosoma cruzi leads to the development of human Chagas' disease, yet the functional contributions of the host cell toward the infection proce...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2012.11.011

    authors： Caradonna KL,Engel JC,Jacobi D,Lee CH,Burleigh BA

    更新日期：2013-01-16 00:00:00