Is There a Link Between Gender Dysphoria and Autism Spectrum Disorder?

Abstract:

:In their Translations article in the January issue of the Journal, Turban and van Schalkwyk provide a critical evaluation of the recently published literature on co-occurring gender dysphoria (GD) and autism spectrum disorder (ASD).1 In addition, they refer to this flux in interest as part of a larger increase in publications on transgender people, which are mostly reviews and do not contain new data. Given the low-grade evidence in this field for most clinical recommendations,2 good-quality research is of great relevance. We support the debate on the GD-ASD literature and acknowledge that translations of the findings to the lay press such as "Do transgender children just have autism?" are not helpful. Also, we agree with many of the limitations brought forward by the authors and acknowledge that, at present, sound underlying evidence for a GD-ASD link is lacking. However, we believe that some nuance in argumentation could help forward the debate of this clinically important topic.

authors

van der Miesen AIR,Cohen-Kettenis PT,de Vries ALC

doi

10.1016/j.jaac.2018.04.022

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

884-885

issue

11

eissn

0890-8567

issn

1527-5418

pii

S0890-8567(18)31288-7

journal_volume

57

pub_type

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    更新日期:1993-09-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1097/00004583-199702000-00008

    authors: Goodyer IM,Herbert J,Secher SM,Pearson J

    更新日期:1997-02-01 00:00:00

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    doi:10.1097/01.CHI.0000070246.24125.6D

    authors: Shoal GD,Giancola PR,Kirillova GP

    更新日期:2003-09-01 00:00:00

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    abstract:OBJECTIVE:To evaluate the feasibility and effectiveness of a school-based group cognitive-behavioral treatment (CBT) for anxiety disorders with African-American adolescents. METHOD:Twelve adolescents (mean age = 15.6 years) with anxiety disorders were randomly assigned to CBT (n = 6) or a group attention-support contr...

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    authors: Ginsburg GS,Drake KL

    更新日期:2002-07-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1097/00004583-199105000-00013

    authors: Harrington R,Fudge H,Rutter M,Pickles A,Hill J

    更新日期:1991-05-01 00:00:00

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    abstract:OBJECTIVE:To study the relationship between child psychiatric disorders and quality of life (QoL). METHOD:In a sample of 310 children (ages 6-18 years) referred for psychiatric problems, children, parents, and clinicians reported on psychopathology and subjective and objective QoL indicators. RESULTS:Six diagnostic c...

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    doi:10.1097/00004583-200402000-00019

    authors: Bastiaansen D,Koot HM,Ferdinand RF,Verhulst FC

    更新日期:2004-02-01 00:00:00

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    doi:10.1097/00004583-199211000-00027

    authors: Garber HJ,McGonigle JJ,Slomka GT,Monteverde E

    更新日期:1992-11-01 00:00:00

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    abstract:OBJECTIVE:This study examined rates of self-harm and suicidality (ideation and behavior) in children referred clinically for gender dysphoria compared with their siblings, and referred and nonreferred children from the Child Behavior Checklist (CBCL) standardization sample. Predictors or correlates of self-harm/suicida...

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    authors: Aitken M,VanderLaan DP,Wasserman L,Stojanovski S,Zucker KJ

    更新日期:2016-06-01 00:00:00

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    doi:10.1097/00004583-199301000-00026

    authors: Ialongo NS,Horn WF,Pascoe JM,Greenberg G,Packard T,Lopez M,Wagner A,Puttler L

    更新日期:1993-01-01 00:00:00

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    abstract::Part II of this review critically evaluates antidepressants' (AD) efficacy in children and adolescents with anxiety, physical, and behavioral disorders as well as AD's side-effect spectrum. AD are administered increasingly to youths with specific anxiety syndromes phenomenologically paralleling those in adults which a...

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    pub_type: 杂志文章,评审

    doi:10.1097/00004583-199305000-00001

    authors: Ambrosini PJ,Bianchi MD,Rabinovich H,Elia J

    更新日期:1993-05-01 00:00:00

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    doi:10.1016/j.jaac.2019.02.009

    authors: Adelson SL,Walker-Cornetta E,Kalish N

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    doi:10.1097/01.chi.0000194568.70912.ee

    authors: Deveaugh-Geiss J,March J,Shapiro M,Andreason PJ,Emslie G,Ford LM,Greenhill L,Murphy D,Prentice E,Roberts R,Silva S,Swanson JM,VAN Zwieten-Boot B,Vitiello B,Wagner KD,Mangum B

    更新日期:2006-03-01 00:00:00

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    authors: Milin R,Halikas JA,Meller JE,Morse C

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    authors: Kaufman J

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    authors: Ougrin D,Tranah T,Stahl D,Moran P,Asarnow JR

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    authors: Marrus N,Faughn C,Shuman J,Petersen SE,Constantino JN,Povinelli DJ,Pruett JR Jr

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