Abstract:
:At least three human cytomegalovirus polypeptides are targets for virus neutralizing antibody; a single protein of 86,000 molecular weight (p86) and two coimmunoprecipitating proteins of 130,000 and 55,000 molecular weight (p130/55). These polypeptides have been isolated by immunoaffinity chromatography and tested for immunogenicity in guinea pigs. Neutralizing antibody was detected after immunization with both p86 and p130/55. Hyperimmune sera to p130/55, but not p86, were dependent upon guinea pig complement for virus neutralization.
journal_name
Virologyjournal_title
Virologyauthors
Rasmussen L,Mullenax J,Nelson M,Merigan TCdoi
10.1016/0042-6822(85)90215-6subject
Has Abstractpub_date
1985-08-01 00:00:00pages
186-90issue
1eissn
0042-6822issn
1096-0341journal_volume
145pub_type
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