p-Coumaric acid stimulates longitudinal bone growth through increasing the serum production and expression levels of insulin-like growth factor 1 in rats.

abstract：:Highly purified bovine heart protein phosphatase 2A catalytic subunit lost virtually all of its activity during storage at -70 degrees. When the enzyme was preincubated with Co2+, over 35% of the original activity was restored. Freshly prepared protein phosphatase 2A purified from bovine heart was stimulated at least ...

journal_title：Biochemical and biophysical research communications

authors： Cai L,Chu Y,Wilson SE,Schlender KK

更新日期：1995-03-08 00:00:00

abstract：:With aging and stress, the myocardium undergoes structural remodeling, often leading to fibrosis. The purpose of this study is to examine whether lumican, one of the class II small leucine-rich proteoglycans, has a protective role in cardiac remodeling and fibrosis. In attempts to elucidate the hypothesis that lumican...

journal_title：Biochemical and biophysical research communications

authors： Chen SW,Tung YC,Jung SM,Chu Y,Lin PJ,Kao WW,Chu PH

更新日期：2017-01-22 00:00:00

abstract：:Cultured human lymphocytes and fibroblasts accumulate methotrexate during 24 hours and synthesize methotrexate polyglutamates up to the hexaglutamate, with the triglutamate predominating. In the interval after incubation with methotrexate, drug is lost, metabolites are converted to longer chain-lengths, and methotrexa...

journal_title：Biochemical and biophysical research communications

authors： Whitehead VM,Kalman TI,Vuchich MJ

更新日期：1987-04-14 00:00:00

abstract：:CD1d is a specific ligand for the invariant Valpha24Vbeta11-natural killer T (iNKT) cells that play an important role in placental development during early human pregnancy. The localization and regulation of placental CD1d expression remain unclear. Immunohistochemistry of human early gestational placentas revealed CD...

journal_title：Biochemical and biophysical research communications

authors： Matsumoto J,Kawana K,Nagamatsu T,Schust DJ,Fujii T,Sato H,Hyodo H,Yasugi T,Kozuma S,Taketani Y

更新日期：2008-06-27 00:00:00

abstract：:Aberrant activation of Notch signaling frequently occurs in liver cancer, and is associated with liver malignancies. However, the mechanisms regulating pathologic Notch activation in hepatocellular carcinoma (HCC) remain unclear. Protein O-fucosyltransferase 1 (Pofut1) catalyzes the addition of O-linked fucose to the ...

journal_title：Biochemical and biophysical research communications

authors： Ma L,Dong P,Liu L,Gao Q,Duan M,Zhang S,Chen S,Xue R,Wang X

更新日期：2016-04-29 00:00:00

abstract：:Survival ("clonogenic ability") and induced DNA repair (SOS repair) have been studied at low X-ray doses in two Escherichia coli strains (GE94 and KY943), both of which contain a recA-lacZ protein fusion. X-ray doses greater than about 0.5 Gray clearly induce SOS repair activity. However, the threshold dose that just ...

journal_title：Biochemical and biophysical research communications

authors： Ewing D

更新日期：1995-01-17 00:00:00

abstract：:The E2F activity plays a critical role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. We describe here molecular cloning and functional characterization of a fifth member of the E2F family of transcription factors. E2F-...

journal_title：Biochemical and biophysical research communications

authors： Vaishnav YN,Vaishnav MY,Pant V

更新日期：1998-01-26 00:00:00

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a well-known immunotoxic compound affecting the expression of inflammatory genes. We found that TCDD induces the expression of the B-cell activating factor of the tumor necrosis factor family (BAFF), B-lymphocyte chemoattractant (BLC), CC-chemokine ligand 1 (CCL1), and the...

journal_title：Biochemical and biophysical research communications

authors： Vogel CF,Sciullo E,Matsumura F

更新日期：2007-11-23 00:00:00

abstract：:The influence of experimental conditions during long-time (72 h) incubations of neonatal mouse calvaria on the measurement of prostaglandins was investigated. Incubations of the cultured calvaria were carried out in the presence and absence of stimulating agents of bone resorption, such as thrombin and parathyroid hor...

journal_title：Biochemical and biophysical research communications

authors： Leis HJ,Malle E,Hoffmann O,Klaushofer K,Fratzl-Zelman N,Koller K,Peterlik M

更新日期：1990-06-15 00:00:00

abstract：:The eukaryotic primase/polymerase complex synthesizes approximately 107 primers, one per Okazaki fragment, during the replication of mammalian chromosomes, which contain 109 base pairs. Primase catalyzes the synthesis of a short RNA segment to a single-stranded DNA template. Primase is important in DNA replication bec...

journal_title：Biochemical and biophysical research communications

authors： Lee JG,Park KR,An JY,Kang JY,Shen H,Wang J,Eom SH

更新日期：2018-12-09 00:00:00

abstract：:This article has been withdrawn at the request of the editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Biochemical and biophysical research communications

authors： Gou X,Yang HA,He WY,Xiao MC,Wang M

更新日期：2010-05-10 00:00:00

abstract：:Single-molecule imaging by scanning tunnelling microscopy (STM) yields the atomic-resolution (0.6A) structure of individual B-type DNA molecules. The strong correlation between these STM structures and those predicted from the known base sequence indicates that sequencing of single DNA molecules using STM may be feasi...

journal_title：Biochemical and biophysical research communications

authors： Zareie MH,Lukins PB

更新日期：2003-03-28 00:00:00

abstract：:Leukotriene B(4) (LTB(4)) is a potent chemoattractant and activator of neutrophils, macrophages and T cells. These cells are a key component of inflammation and all express BLT1, a high affinity G-protein-coupled receptor for LTB(4). However, little is known about the neuroimmune functions of BLT1. In this study, we d...

journal_title：Biochemical and biophysical research communications

authors： Kihara Y,Yokomizo T,Kunita A,Morishita Y,Fukayama M,Ishii S,Shimizu T

更新日期：2010-04-09 00:00:00

abstract：:MH1C1 rat hepatoma cells express the alpha isoenzyme as the only phorbol-ester sensitive isoform of protein kinase C (PKC). In this cell line, phorbol 12-myristate 13-acetate (PMA) induced a marked, dose-dependent growth inhibition. The administration of the PKC inhibitor staurosporine was able to mimic the effect of ...

journal_title：Biochemical and biophysical research communications

authors： Perletti GP,Smeraldi C,Porro D,Piccinini F

更新日期：1994-12-30 00:00:00

abstract：:Signalling through the chemokine stromal derived factor (SDF)-1alpha and its receptor CXCR4 has been recognized as a key event in the migratory response of hematopoietic stem and progenitor cells (HPC). Small GTPases of the Rho/Rac family might be involved in SDF-1alpha signalling at several different levels. In the p...

journal_title：Biochemical and biophysical research communications

authors： Henschler R,Piiper A,Bistrian R,Möbest D

更新日期：2003-11-28 00:00:00

abstract：:Silver nanoparticles (AgNPs) are one of the most commonly used nanomaterials; however, it remains unclear whether AgNPs induce neurotoxicity. Here, we investigated the potential neurological effects of AgNPs and the neuroprotective effect of vitamin E (VE). We found that intranasal instillation of AgNPs in neonatal Sp...

journal_title：Biochemical and biophysical research communications

authors： Yin N,Yao X,Zhou Q,Faiola F,Jiang G

更新日期：2015-03-06 00:00:00

abstract：:The products of the human hepatitis B virus (HBV) and woodchuck hepatitis B virus X genes (pXs) transactivate homologous and heterologous genes including the HBV-X and core promoters, the human immunodeficiency viruses 1 (HIV-1) and 2 (HIV-2) long terminal repeats and the beta interferon regulatory sequences. We repor...

journal_title：Biochemical and biophysical research communications

authors： Balsano C,Avantaggiati ML,Natoli G,De Marzio E,Will H,Perricaudet M,Levrero M

更新日期：1991-05-15 00:00:00

abstract：:XAF1 (XIAP-associated factor 1) binds to XIAP and blocks its anti-apoptotic activity. It has been reported that XAF1 is mainly expressed in normal tissues but is missing or present at low levels in most cancer cell lines, which implies a tumor-suppressing function. In the present study we describe the identification o...

journal_title：Biochemical and biophysical research communications

authors： Yin W,Cheepala S,Clifford JL

更新日期：2006-01-27 00:00:00

abstract：:The rat thyrotropin receptor (TSHR) has 7 Cys residues in its transmembrane (TM) segments. We investigated the roles of these Cys residues by individually mutating each to Ser, transfecting the mutant DNA into Cos-7 cells and measuring TSH binding and cAMP/phosphoinositide (PIP2) responses to TSH and Graves' IgGs. Mut...

journal_title：Biochemical and biophysical research communications

authors： Kosugi S,Mori T

更新日期：1996-05-24 00:00:00

abstract：:The environmental toxin, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a wasting syndrome marked by hypophagia, loss of body fat, changes in intermediary metabolism and death. Use of conventional laboratory animals has not resolved whether or not TCDD affects intermediary metabolism independently of hypophagia. We...

journal_title：Biochemical and biophysical research communications

authors： Lentnek M,Griffith OW,Rifkind AB

更新日期：1991-02-14 00:00:00

abstract：:The effect of HMG1 on the transcriptional block caused by left-handed Z-form in a highly negatively supercoiled DNA was examined using a supercoiled plasmid containing a (CG)10 sequence downstream of promoters. The transcription by E. coli RNA polymerase was blocked at the boundary of alternating CG sequence in the Z-...

journal_title：Biochemical and biophysical research communications

authors： Waga S,Mizuno S,Yoshida M

更新日期：1988-05-31 00:00:00

abstract：:Labial grooves in maxillary incisors have been reported in several wild-type rodent species. Previous studies have reported age-dependent labial grooves occur in moderate prevalence in C57BL/6 mice; however, very little is known about the occurrence of such grooves. In the present study, we observed age-dependent groo...

journal_title：Biochemical and biophysical research communications

authors： Ota MS,Kondo K,Li Y,Iseki S,Yamashita A,Gibson CW,Kondo T

更新日期：2018-02-05 00:00:00

abstract：:Using antibodies to the procollagen C-proteinase enhancer of mouse fibroblast culture medium, we have screened by immunoblotting extracts of several post natal mouse and rat tissues for the presence of the enhancer antigen. All rodent connective tissues were relatively rich in enhancer; lower amounts were found in ske...

journal_title：Biochemical and biophysical research communications

authors： Kessler E,Mould AP,Hulmes DJ

更新日期：1990-11-30 00:00:00

abstract：:Prostate cancer (CaP) bone metastasis is an early event that remains inactive until later-stage progression. Reduced levels of circulating androgens, due to andropause or androgen deprivation therapies, alter androgen receptor (AR) coactivator expression. Coactivators shift the balance towards enhanced AR-mediated gen...

journal_title：Biochemical and biophysical research communications

authors： Villagran MA,Gutierrez-Castro FA,Pantoja DF,Alarcon JC,Fariña MA,Amigo RF,Muñoz-Godoy NA,Pinilla MG,Peña EA,Gonzalez-Chavarria I,Toledo JR,Rivas CI,Vera JC,McNerney EM,Onate SA

更新日期：2015-11-27 00:00:00

abstract：:Although it is widely accepted that insulin stimulates leptin secretion, a dual action was observed using a validated in vitro system, i.e., an early (less than 48 h) inhibitory action, followed later (48-96 h) by a clear-cut stimulation. While the inhibitory phase was observed at every glucose concentration tested (f...

journal_title：Biochemical and biophysical research communications

authors： Casabiell X,Piñeiro V,De la Cruz LF,Gualillo O,Folgar L,Diéguez C,Casanueva FF

更新日期：2000-09-24 00:00:00

abstract：:The earthworm Lumbricus rubellus has been found to inhabit cadmium-rich soils and accumulate cadmium within its tissues. Two metallothionein (MT) isoforms (1 and 2) have been identified and cloned from L. rubellus. In this study, we address the metalation status, metal coordination, and structure of recombinant MT-2 f...

journal_title：Biochemical and biophysical research communications

authors： Ngu TT,Sturzenbaum SR,Stillman MJ

更新日期：2006-12-08 00:00:00

abstract：:Escherichia coli isoleucyl-tRNA synthetase has been shown to contain two enzyme-bound zinc atoms per polypeptide chain. To investigate the structural and functional significance of the C-terminal enzyme-bound zinc, mutagenesis was used to alter Cys 922 to Ser [IleRS(C922S)] and to replace Cys 922 through Ala 939 with ...

journal_title：Biochemical and biophysical research communications

authors： Zhou L,Rosevear PR

更新日期：1995-11-13 00:00:00

abstract：:Biotin protein ligase (BPL) is an enzyme mediating biotinylation of a specific lysine residue of the carboxyl carrier protein (BCCP) of biotin-dependent enzymes. We recently found that the substrate specificity of BPL from archaeon Sulfolobus tokodaii is totally different from those of many other organisms, in reflect...

journal_title：Biochemical and biophysical research communications

authors： Sueda S,Li YQ,Kondo H,Kawarabayasi Y

更新日期：2006-05-26 00:00:00

abstract：:In a chicken B cell line, DT40, the disruption of HDAC2 (chHDAC2) gene causes an alteration of several gene expressions including chicken IgM light chain (chIgM-L) gene by 2D-PAGE analysis. To investigate the transcriptional function of chHDAC2, we employed the chIgM-L promoter reporter plasmid. We found that chHDAC2 ...

journal_title：Biochemical and biophysical research communications

authors： Takechi S,Adachi M,Nakayama T

更新日期：2002-11-29 00:00:00

abstract：:With co-treatment of potassium oxonate (PO) and xanthine sodium salt (XSS), a zebrafish larva model of acute hyperuricemia has been constructed for the first time. The results show PO 200 μM + XSS 10 μM, PO 300 μM + XSS 15 μM, and PO 400 μM + XSS 20 μM can significantly increase the level of uric acid in the zebrafish...

journal_title：Biochemical and biophysical research communications

authors： Zhang Y,Li Q,Wang F,Xing C

更新日期：2019-01-08 00:00:00