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Procollagen type I C-proteinase enhancer is a naturally occurring connective tissue glycoprotein.

Abstract：

:Using antibodies to the procollagen C-proteinase enhancer of mouse fibroblast culture medium, we have screened by immunoblotting extracts of several post natal mouse and rat tissues for the presence of the enhancer antigen. All rodent connective tissues were relatively rich in enhancer; lower amounts were found in skeletal muscle and heart and essentially no enhancer was detected in kidney, liver or brain. The amounts of enhancer in mouse tendon and calvaria extracts were age related, with highest amounts in 11 and 19 d tendons and in 1 d calvaria-the times of rapid growth of these organs. The results suggest that procollagen C-proteinase enhancer is a specific connective tissue glycoprotein that is likely to regulate procollagen processing in vivo.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Kessler E,Mould AP,Hulmes DJ

doi

10.1016/s0006-291x(05)81024-1

subject

Has Abstract

pub_date

1990-11-30 00:00:00

pages

81-6

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(05)81024-1

journal_volume

173

pub_type

杂志文章

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