Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and β-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats.

abstract：OBJECTIVE:To report on survival and complications after insertion of self-expandable stents in patients with malignant oesophageal stenosis. MATERIAL AND METHODS:Data were gathered retrospectively from the medical records of 92 consecutive patients in the period 1994-2003. The study comprised 68 men and 24 women (medi...

journal_title：Scandinavian journal of gastroenterology

authors： Johnson E,Enden T,Noreng HJ,Holck-Steen A,Gjerlaug BE,Morken T,Johannessen HO,Drolsum A

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Up to date we lack a detailed description of the colorectal endoscopic submucosal dissection (ESD) learning curve, that would represent the experience of the Western center. The aim of this study was to define the critical points of the learning curve and to draw up lesions qualification guidelines tailored ...

journal_title：Scandinavian journal of gastroenterology

authors： Spychalski M,Skulimowski A,Dziki A,Saito Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Zinc (Zn) is protective and enhances epithelial repair in gut diseases. In this study we investigate the localization and distribution of Zn and its binding protein, metallothionein (MT), in the gut of rats fed diets varying in Zn content. METHODS:Male-Sprague Dawley rats were fed low, normal, high, or exce...

journal_title：Scandinavian journal of gastroenterology

authors： Tran CD,Butler RN,Howarth GS,Philcox JC,Rofe AM,Coyle P

更新日期：1999-07-01 00:00:00

abstract：INTRODUCTION:Immunosuppression, the cornerstone of management of Crohn's disease (CD) and ulcerative colitis (UC) (inflammatory bowel diseases; IBD) is associated with an increased risk of serious infections that is inadequately predicted by clinical risk factors. The role of genetics in determining susceptibility to i...

journal_title：Scandinavian journal of gastroenterology

authors： Sasidharan S,Yajnik V,Khalili H,Garber J,Xavier R,Ananthakrishnan AN

更新日期：2017-05-01 00:00:00

abstract：:Simultaneous 22-h measurements of intra-oesophageal and intragastric pH were made in 22 patients with symptoms of gastro-oesophageal reflux (7 with peptic oesophagitis, 8 with peptic oesophageal stricture, and 7 with peptic oesophagitis and previous partial gastrectomy) to determine whether alkaline intra-oesophageal ...

journal_title：Scandinavian journal of gastroenterology

authors： Penagini R,Yuen H,Misiewicz JJ,Bianchi PA

更新日期：1988-08-01 00:00:00

abstract：:Ambulatory 24-h esophageal pH monitoring was carried out in 54 patients with erosive/ulcerative reflux esophagitis before a 12- to 24-week treatment with either ranitidine, 150 to 300 mg twice daily, or famotidine, 20 to 40 mg twice daily. After this period, 21 patients continued to present endoscopic evidence of esop...

journal_title：Scandinavian journal of gastroenterology

authors： Bianchi Porro G,Pace F,Sangaletti O

更新日期：1990-08-01 00:00:00

abstract：:In a series of 45 consecutive duodenal ulcer patients (DU) the activities of 10 marker enzymes from the brush border, basolateral membrane, mitochondria, and lysosomes were determined by analysis of homogenized material taken with biopsy forceps through an endoscope from the antral and body part of the stomach. They w...

journal_title：Scandinavian journal of gastroenterology

authors： Vetvik K,Schrumpf E,Andersen KJ,Børkje B,Odegaard S,Skagen DW,Halvorsen OJ

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVE:To examine some typical histological findings in Crohn's disease using high-frequency ultrasound and to define the echo properties of these findings. MATERIAL AND METHODS:Bowel resection specimens from 14 patients operated on for Crohn's disease were examined with a 10 MHz linear array ultrasound transducer ...

journal_title：Scandinavian journal of gastroenterology

authors： Nylund K,Leh S,Immervoll H,Matre K,Skarstein A,Hausken T,Gilja OH,Birger Nesje L,Ødegaard S

更新日期：2008-01-01 00:00:00

abstract：:Prostaglandins of the E type stimulate bicarbonate secretion by the duodenal mucosa and inhibit gastric acid secretion, effects that have been related to their anti-ulcer activity. Leukotrienes constitute a more recently discovered branch of the arachidonic acid cascade, and C4 and D4 have been suggested to be ulcerog...

journal_title：Scandinavian journal of gastroenterology

authors： Knutson L,Nimbratt C,Flemström G

更新日期：1988-12-01 00:00:00

abstract：:Forty-eight patients with symptomatic duodenal ulcer were randomized to 4 weeks' treatment with cimetidine, 1 g/day (C4), or 1 week of cimetidine treatment followed by 3 weeks of placebo (C1 + P). The study was performed double blind. The symptoms were recorded daily on a visual analogue scale. Endoscopy was performed...

journal_title：Scandinavian journal of gastroenterology

authors： Johannessen T,Kristensen P,Fjøsne U,Hafstad PE,Kleveland PM,Løge I,Sandbakken P,Petersen H

更新日期：1986-08-01 00:00:00

abstract：:Jejunal biopsy in 33 patients before and after intestinal shunt operation for obesity has demonstrated that neither surface nor volume of the villi increase after surgery. Specific disaccharidase activity remained unchanged, and specific alkaline phosphatase activity increased slightly. There was a significant decreas...

journal_title：Scandinavian journal of gastroenterology

authors： Danö P,Nielsen OV,Petri M,Jörgensen B

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Hepatic stimulator substance (HSS) is a known hepatic growth factor that appears to be organ-specific but species-nonspecific. In the present study we investigated the effect of HSS administration in a rat model of liver injury and regeneration induced by thioacetamide (TAA) injection. METHODS:TAA (300 mg/k...

journal_title：Scandinavian journal of gastroenterology

authors： Theocharis SE,Margeli AP,Agapitos EV,Mykoniatis MG,Kittas CN,Davaris PS

更新日期：1998-06-01 00:00:00

abstract：:Complicating disorders in various organs outside the intestinal tract are common in ulcerative colitis. This report deals with the occurrence of nephrotic syndrome in two patients with long-standing ulcerative colitis. In the patient studied in most detail, 2 episodes have taken place, the first developing into uremia...

journal_title：Scandinavian journal of gastroenterology

authors： Stokke KT,Teisberg PA,Myhre E,Hovig T,Flatmark A,Gjone E

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF alpha) and beta (TNF beta) appear to play an important role in the regulation of the inflammatory response. The aim of the present study was to investigate the intrinsic capacity of peripheral blood mononuclear cells (PBMC) to produce these cytokines. METHODS:PBMC from 41 pa...

journal_title：Scandinavian journal of gastroenterology

authors： Bouma G,Oudkerk Pool M,Scharenberg JG,Kolkman JJ,von Blomberg BM,Scheper RJ,Meuwissen SG,Peña AS

更新日期：1995-11-01 00:00:00

abstract：:Antral exclusion was performed in seven adult male Sprague-Dawley rats, which were killed 10 weeks later. Fasting serum gastrin concentrations were almost four times higher than in unoperated controls. There was a slight increase in the thickness of the gastric mucosa, but quantitative electron microscopy showed no si...

journal_title：Scandinavian journal of gastroenterology

authors： Helander HF,Liedberg G,Rehfeld JF

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the role of 8-OHdG (8-hydroxy-2'-deoxyguanosine) detecting oxidative stress response following cholecystectomy in a randomised multicentre study of patients with minilaparotomy cholecystectomy (MC) versus laparoscopic cholecystectomy (LC). METHODS:Initially, 106 patients ...

journal_title：Scandinavian journal of gastroenterology

authors： Aspinen S,Harju J,Juvonen P,Selander T,Kokki H,Pulkki K,Eskelinen MJ

更新日期：2016-12-01 00:00:00

abstract：:The jejunal disposal of perfused acid was studied in 11 control subjects and 12 patients with duodenal ulcer. It was found that the capacity to dispose of acid was saturable and was less than control in patients with duodenal ulcer. When the load of acid was small, all the acid disappeared from the jejunum and sodium ...

journal_title：Scandinavian journal of gastroenterology

authors： Thjodleifsson B,Wormsley KG

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Accurate biomarkers for quantifying liver fibrosis are important for clinical practice and trial end-points. We compared the diagnostic performance of magnetic resonance imaging (MRI), including gadoxetate-enhanced MRI and 31P-MR spectroscopy, with fibrosis stage and serum fibrosis algorithms in a c...

journal_title：Scandinavian journal of gastroenterology

authors： Forsgren MF,Nasr P,Karlsson M,Dahlström N,Norén B,Ignatova S,Sinkus R,Cedersund G,Leinhard OD,Ekstedt M,Kechagias S,Lundberg P

更新日期：2020-07-01 00:00:00

abstract：:Seventy-eight young patients with symptoms of chronic inflammatory bowel disease (IBD) of the colon have been investigated to determine to what degree colonoscopy adds important information for the diagnosis of IBD in addition to results of the routine procedures, including rectosigmoidoscopy carried out at the same t...

journal_title：Scandinavian journal of gastroenterology

authors： Holmquist L,Rudic N,Ahren C,Fällström SP

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:As data is limited on the outcomes of calcineurin inhibitors (CNI) in autoimmune hepatitis (AIH), we evaluated the efficacy and safety of CNI in AIH patients who failed prior treatment(s). METHODS:A retrospective study was performed of AIH patients who received cyclosporine A (CsA) and/or tacrolimus (TAC) a...

journal_title：Scandinavian journal of gastroenterology

authors： Roberts SK,Strasser SI,Nicoll AJ,Kemp W,Majeed A,Mitchell J,Stuart K,Gow P,Sood S,MacQuillan G,George J,Mitchell J,McCaughan GW,ALA Clinical Research Network.

更新日期：2020-11-01 00:00:00

abstract：:Psychologic and social factors have been implicated in the aetiology of dyspepsia. In this study these factors were investigated in relation to flatulent dyspepsia, a symptom complex that has traditionally been associated with gallbladder disease. Subjects completed the Middlesex Hospital Questionnaire and the Life Ev...

journal_title：Scandinavian journal of gastroenterology

authors： Watson RG,Younge RJ,Lewis SA,Love AH

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:Pancreatic cancer continues to be an urgent clinical problem. We used the novel DNA methyltransferase inhibitor Zebularine and the histone deacetylase inhibitor SAHA to investigate the epigenetic influence on viability and differentiation of the pancreatic cancer cell lines YAP C, DAN G and Panc-89 in vitro a...

journal_title：Scandinavian journal of gastroenterology

authors： Neureiter D,Zopf S,Leu T,Dietze O,Hauser-Kronberger C,Hahn EG,Herold C,Ocker M

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Enteric neuropathy with mild inflammation (ganglionitis) has been described in several motility disorders including irritable bowel syndrome (IBS), enteric dysmotility (ED), slow-transit constipation (STC) and chronic intestinal pseudo-obstruction (CIPO). The purpose of this study was to test the hypothesis t...

journal_title：Scandinavian journal of gastroenterology

authors： Törnblom H,Lang B,Clover L,Knowles CH,Vincent A,Lindberg G

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:We assessed the controversial topic of using 22-gauge needles in endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for the diagnosis and evaluation of Ki67 labeling indices (Ki67LI) of pancreatic neuroendocrine tumors (pNET). METHODS:Thirty-eight patients with pNET who underwent EUS-FNA between ...

journal_title：Scandinavian journal of gastroenterology

authors： Unno J,Kanno A,Masamune A,Kasajima A,Fujishima F,Ishida K,Hamada S,Kume K,Kikuta K,Hirota M,Motoi F,Unno M,Shimosegawa T

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:Faecal Calprotectin (FC) is a sensitive marker for gut inflammation. However, slightly elevated FC levels are also common in subjects without inflammation. We investigated the association between FC and clinical factors including concomitant use of medical therapy in patients with a normal colonoscopy. MATE...

journal_title：Scandinavian journal of gastroenterology

authors： Lundgren D,Eklöf V,Palmqvist R,Hultdin J,Karling P

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Topical treatment is effective in patients with distal ulcerative colitis. This trial compares the efficacy, safety, and practicality of 4 weeks' treatment with 500 mg mesalazine suppositories with those of 178 mg hydrocortisone foam, both given twice daily. METHODS:Seventy-nine patients with distal ulcerat...

journal_title：Scandinavian journal of gastroenterology

authors： Farup PG,Hovde O,Halvorsen FA,Raknerud N,Brodin U

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:Exclusive polymeric diet enriched with transforming growth factor-beta 2 (ANS-TGF-β2) has been used for remission induction and maintenance in pediatric Crohn's disease (CD). Its use in the preoperative setting has never been evaluated. The aim of this study was to evaluate preoperative ANS-TGF-β2 to decrease...

journal_title：Scandinavian journal of gastroenterology

authors： Beaupel N,Brouquet A,Abdalla S,Carbonnel F,Penna C,Benoist S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Small bowel angiodysplasias (SBA) account for 50% of obscure gastrointestinal bleeding. Lesions bleed recurrently and current treatments are relatively ineffective at reducing re-bleeding. Little is known about the natural history of SBA which is needed to guide treatment decisions and counsel patients on pr...

journal_title：Scandinavian journal of gastroenterology

authors： Holleran G,Hall B,Zgaga L,Breslin N,McNamara D

更新日期：2016-01-01 00:00:00

abstract：:C-kit gene gain of function mutations are important in the pathogenesis of gastrointestinal stromal tumors (GISTs). Imatinib is a selective tyrosine kinase inhibitor of KIT and achieves a partial response or stable disease in most patients with metastatic GIST, but there is increasing evidence of acquired resistance. ...

journal_title：Scandinavian journal of gastroenterology

authors： Zheng S,Pan YL,Tao DY,Wang JL,Huang KE

更新日期：2009-01-01 00:00:00

abstract：:In a series of 36 consecutive patients with proved idiopathic hemochromatosis and with a mean follow-up time of 8 years, 10 patients developed 11 carcinomas (30.6%). Five patients had hepatomas and six patients extrahepatic carcinoma involving lungs (four), oral cavity (one), and thyroid (one). The findings suggest a ...

journal_title：Scandinavian journal of gastroenterology

authors： Ammann RW,Müller E,Bansky J,Schüler G,Häcki WH

更新日期：1980-01-01 00:00:00