Backbone and side-chain (1)H, (13)C, and (15)N NMR assignments of the N-terminal domain of Escherichia coli LpoA.

abstract：:Chromatin remodelling proteins are an essential family of eukaryotic proteins. They harness the energy from ATP hydrolysis and apply it to alter chromatin structure in order to regulate all aspects of genome biology. Chromodomain helicase DNA-binding protein 1 (CHD1) is one such remodelling protein that has specialise...

journal_title：Biomolecular NMR assignments

authors： Mohanty B,Silva AP,Mackay JP,Ryan DP

更新日期：2016-04-01 00:00:00

abstract：:The S100 family belongs to the EF-hand calcium-binding proteins regulating a wide range of important cellular processes via protein-protein interactions. Most S100 proteins adopt a conformation of non-covalent homodimer for their functions. Calcium binding to the EF-hand motifs of S100 proteins is essential for trigge...

journal_title：Biomolecular NMR assignments

authors： Hung KW,Chang YM,Yu C

更新日期：2013-10-01 00:00:00

abstract：:The A. thaliana RCD1 (radical-induced cell death1) protein is a cellular signaling hub protein which interacts with numerous plant transcription factors from different families. It consists of three conserved domains and intervening unstructured regions, the C-terminal RST domain being responsible for the interactions...

journal_title：Biomolecular NMR assignments

authors： Tossavainen H,Hellman M,Vainonen JP,Kangasjärvi J,Permi P

更新日期：2017-10-01 00:00:00

abstract：:The replication of the hepatitis B virus is initiated by binding of the viral reverse transcriptase protein complex to the apical stem loop of the epsilon element to place it next to the primer loop, from which a four nucleotide DNA primer is subsequently synthesized. Here, we present the (1)H/(13)C/(15)N NMR assignme...

journal_title：Biomolecular NMR assignments

authors： van der Werf RM,Girard FC,Nelissen F,Tessari M,Wijmenga SS

更新日期：2008-12-01 00:00:00

abstract：:RpsA, also known as ribosomal protein S1, is an essential protein required for translation initiation of mRNAs when their Shine-Dalgarno sequence is degenerated (Sorensen et al. 1998). In addition, RpsA of Mycobacterium tuberculosis (M. tb) is involved in trans-translation, which is an effective system mediated by tmR...

journal_title：Biomolecular NMR assignments

authors： Fu J,Huang B,Lin D,Liao X

更新日期：2017-10-01 00:00:00

abstract：:GNA2132 (Genome-derived Neisseria Antigen 2132) is a surface-exposed lipoprotein discovered by reverse vaccinology and expressed by genetically diverse Neisseria meningitidis strains (Pizza et al. 2000). The protein induces bactericidal antibodies against most strains of Meningococccus and has been included in a multi...

journal_title：Biomolecular NMR assignments

authors： Esposito V,Musi V,Veggi D,Pastore A,Pizza M

更新日期：2010-04-01 00:00:00

abstract：:S100A15 (koebnerisin) is overexpressed in psoriatic skin and displays distinct localizations in skin and breast with divergent functions in inflammation. Here we report the backbone and side-chain resonance assignments for the Ca(2+)-bound human S100A15. ...

journal_title：Biomolecular NMR assignments

authors： Cho CC,Hung KW,Yu C

更新日期：2014-04-01 00:00:00

abstract：:Tuberculosis is one of the deadliest diseases worldwide affecting approximately 10 million people in 2018. This classifies tuberculosis as epidemic in several countries and leads to an increasing number of multidrug-resistant strains. Thus, the development of new drugs is essential to effective treatments. A potential...

journal_title：Biomolecular NMR assignments

authors： Bartkevihi L,Martins B,de Oliveira DMP,Pires JRM,Anobom CD,Almeida FCL

更新日期：2020-04-01 00:00:00

abstract：:The archaeal protein L7Ae forms part of a protein complex in the ribosome that specifically recognizes and binds to kink-turn RNA. In this complex, L7Ae directly interacts with the oligonucleotide and creates a functional arrangement for site-specific 2'-O-methylation. We report the solution NMR backbone assignment of...

journal_title：Biomolecular NMR assignments

authors： Moschen T,Wunderlich C,Kreutz C,Tollinger M

更新日期：2015-04-01 00:00:00

abstract：:We report the nearly complete 1H, 13C and 15N resonance assignments of the oxidized form (Cys(67)-Cys(70)) of the N-terminal domain of PilB from Neisseria meningitidis. Secondary structure determination using CSI method and TALOS leads mainly to the prediction of 7 alpha-helical and 5 beta-sheet parts. ...

journal_title：Biomolecular NMR assignments

authors： Quinternet M,Beaufils C,Neiers F,Tsan P,Boschi-Muller S,Averlant-Petit MC,Branlant G,Cung MT

更新日期：2007-07-01 00:00:00

abstract：:Parkinson's disease (PD) is a chronic, progressive neurodegenerative disease, where dopaminergic cells die most prominently in the area of substantia nigra. Neurotrophic factors (NTFs) are secreted proteins, which upon binding to their target receptors trigger survival pathways to prevent neuronal loss. Recently disco...

journal_title：Biomolecular NMR assignments

authors： Hellman M,Peränen J,Saarma M,Permi P

更新日期：2010-10-01 00:00:00

abstract：:The gelation factor from Dictyostelium discoideum (ABP-120) is an actin binding protein consisting of six immunoglobulin (Ig) domains in the C-terminal rod domain. We have recently used the pair of domains 5 and 6 of ABP-120 as a model system for studying multi-domain nascent chain folding on the ribosome. Here we pre...

journal_title：Biomolecular NMR assignments

authors： Hsu ST,Cabrita LD,Christodoulou J,Dobson CM

更新日期：2009-06-01 00:00:00

abstract：:The Src tyrosine kinase is the paradigm of an oncogenic kinase, and of regulation by intramolecular inhibitory interactions, as well as an important anticancer target due to its roles in cell proliferation and metastasis. The assignment of backbone (1)H(N), (13)C(α), (13)CO, and (15)N, and sidechain (13)C(β) resonance...

journal_title：Biomolecular NMR assignments

authors： Campos-Olivas R,Marenchino M,Scapozza L,Gervasio FL

更新日期：2011-10-01 00:00:00

abstract：:Hsp70 chaperone proteins play crucial roles in the cell. Extensive structural and functional studies have been performed for bacterial and mammalian Hsp70s. Ssa1 from Saccharomyces cerevisiae is a member of the Hsp70 family. In vivo and biochemical studies on Ssa1 have revealed that it regulates prion propagation and ...

journal_title：Biomolecular NMR assignments

authors： Hu W,Wu H,Zhang H,Gong W,Perrett S

更新日期：2015-10-01 00:00:00

abstract：:The cDNA of UVI31+ was cloned from C. reinhardtii and expressed in E. coli from where the protein was purified to homogeneity. The purified protein exhibited beta-lactamase activity (Manuscript in preparation). However, UVI31+ has no homology with the known β-lactamases. In order to understand the structural basis of ...

journal_title：Biomolecular NMR assignments

authors： Rout AK,Minda R,Peri D,Ramakrishnan V,Bhattacharjee SK,Rao BJ,Chary KV

更新日期：2010-10-01 00:00:00

abstract：:Immunoglobulin E (IgE) plays a central role in allergic reactions. IgE is a dynamic molecule that is capable of undergoing large conformational changes. X-ray crystal structures of the Fc region of IgE in complex with various ligands have shown that IgE-Fc can exist in extended and various bent conformations. IgE-Fc c...

journal_title：Biomolecular NMR assignments

authors： Benjamin SV,Creeke PI,Henry AJ,McDonnell JM

更新日期：2020-04-01 00:00:00

abstract：:Norovirus protease cleaves the virus-encoded polyprotein into six mature nonstructural proteins, presenting itself as an essential enzyme for the viral replication as well as an attractive target for the antiviral drug development. A deeper understanding of the structural mechanism of the protease-substrates/inhibitor...

journal_title：Biomolecular NMR assignments

authors： Takahashi D,Kim Y,Chang KO,Anbanandam A,Prakash O

更新日期：2012-04-01 00:00:00

abstract：:The protein dimethyladenosine transferase 1 (Dim1) is a highly conserved protein occurring in organisms ranging from bacteria such as E. coli where it is named KsgA to humans. Since Dim1 is involved in the biogenesis of the small ribosomal subunit it is an essential protein. During ribosome biogenesis Dim1 acts as an ...

journal_title：Biomolecular NMR assignments

authors： Kaiser M,Hacker C,Duchardt-Ferner E,Wöhnert J

更新日期：2019-10-01 00:00:00

abstract：:Translationally-controlled tumor protein (TCTP) is a eukaryote-conserved protein with crucial roles in cellular growth. It has also been proposed that plant TCTP has functions specific to plant, while no structure of TCTP from photosynthetic organism has been reported. Nannochloropsis is a photosynthetic microalga wit...

journal_title：Biomolecular NMR assignments

authors： Yao X,Xiao Y,Cui Q,Feng Y

更新日期：2015-10-01 00:00:00

abstract：:Sulfolobus solfataricus DNA polymerase IV (Dpo4), a prototype Y-family DNA polymerase, contains a unique little finger domain besides a catalytic core. Here, we report the chemical shift assignments for the backbone nitrogens, α and β carbons, and amide protons of the little finger domain of Dpo4. This work and our pu...

journal_title：Biomolecular NMR assignments

authors： Ma D,Fowler JD,Suo Z

更新日期：2011-10-01 00:00:00

abstract：:Imatinib (Glivec or Gleevec) potently inhibits the tyrosine kinase activity of BCR-ABL, a constitutively activated kinase, which causes chronic myelogenous leukemia (CML). Here we report the first almost complete backbone assignment of c-ABL kinase domain in complex with imatinib. ...

journal_title：Biomolecular NMR assignments

authors： Vajpai N,Strauss A,Fendrich G,Cowan-Jacob SW,Manley PW,Jahnke W,Grzesiek S

更新日期：2008-06-01 00:00:00

abstract：:Phosphoenolpyruvate binding to the C-terminal domain (EIC) of enzyme I of the bacterial phosphotransferase system (PTS) initiates a phosphorylation cascade that results in sugar translocation across the cell membrane and controls a large number of essential pathways in bacterial metabolism. EIC undergoes an expanded t...

journal_title：Biomolecular NMR assignments

authors： Dotas RR,Venditti V

更新日期：2018-04-01 00:00:00

abstract：:The pathogenic bacterium Staphylococcus aureus has evolved to actively evade many aspects of the human innate immune system by expressing a series of secreted inhibitory proteins. Among these, the extracellular adherence protein (Eap) has been shown to inhibit the classical and lectin pathways of the complement system...

journal_title：Biomolecular NMR assignments

authors： Woehl JL,Takahashi D,Herrera AI,Geisbrecht BV,Prakash O

更新日期：2016-10-01 00:00:00

abstract：:Nuclear Factor κB (NF-κB) is a family of five related transcription factors that recognize a κB DNA element on the promoter and enhancer regions of target genes and modulate their expression. Here we report a complete set of 1H, 13C, 15N backbone and side chain resonance assignments for the p50 DNA binding and dimeriz...

journal_title：Biomolecular NMR assignments

authors： Singh A,Dyson HJ

更新日期：2020-09-16 00:00:00

abstract：:Latent TGFβ binding protein 1 (LTBP1) is a large extracellular protein that has been shown to bind covalently to the propeptide of TGFβ cytokines and form a large latent complex, which is then incapable of binding TGFβ receptors. LTBP1 has also been demonstrated to interact with a number of insoluble extracellular mat...

journal_title：Biomolecular NMR assignments

authors： Robertson IB,Handford PA,Redfield C

更新日期：2014-04-01 00:00:00

abstract：:We report NMR assignments of the protein backbone of the C-terminal domain (163 a.a.) of human class 1 translation termination factor eRF1. It was found that several protein loop residues exist in two slowly interconverting conformational states. ...

journal_title：Biomolecular NMR assignments

authors： Mantsyzov AB,Ivanova EV,Birdsall B,Kolosov PM,Kisselev LL,Polshakov VI

更新日期：2007-12-01 00:00:00

abstract：:PRK1 is a member of the protein kinase C-related kinase (PRK) family of serine/threonine kinases and a downstream effector of Rho GTPases. PRK1 has three N-terminal Homology Region 1 (HR1) domains (HR1a, HR1b and HR1c), which form antiparallel coiled coils that interact with Rho family GTPases. PRK1 also has a C2-like...

journal_title：Biomolecular NMR assignments

authors： Sophocleous G,Wood G,Owen D,Mott HR

更新日期：2020-10-01 00:00:00

abstract：:Nervous necrosis virus (NNV) is a non-enveloped virus that causes massive mortality in aquaculture fish production worldwide. Recently X-ray crystallography and single particle cryo-EM have independently determined the icosahedral capsid of NNV to near-atomic resolutions to show the capsid protein is composed of a S-d...

journal_title：Biomolecular NMR assignments

authors： Štěrbová P,Wu D,Lou YC,Wang CH,Chang WH,Tzou DM

更新日期：2020-04-01 00:00:00

abstract：:As part of our NMR structure determination of the Human S100A1, we report nearly complete NMR chemical shift assignments for the (1)H, (13)C and (15)N nuclei. ...

journal_title：Biomolecular NMR assignments

authors： Gupta AA,Mohan SK,Chin Y

更新日期：2012-10-01 00:00:00

abstract：:The homeobox gene (HOXA13) codes for a transcription factor protein that binds to AT-rich DNA sequences and controls expression of many important proteins during embryonic morphogenesis. We report complete NMR chemical shift assignments of the mouse HOXA13 DNA binding domain (A13DBD; BMRB no. 16252). ...

journal_title：Biomolecular NMR assignments

authors： Zhang Y,Thornburg CK,Stadler HS,Ames JB

更新日期：2009-12-01 00:00:00