Resonance assignments for the substrate binding domain of Hsp70 chaperone Ssa1 from Saccharomyces cerevisiae.

abstract：:ITCH (aka Atrophin-1-interacting protein 4) is a prominent member of the NEDD4 HECT (Homologous to E6AP C-Terminus) E3 ubiquitin ligase family that regulates numerous cellular functions including inflammatory responses through T-cell activation, cell differentiation, and apoptosis. Known intracellular targets of ITCH-...

journal_title：Biomolecular NMR assignments

authors： Beasley SA,Bardhi R,Spratt DE

更新日期：2019-04-01 00:00:00

abstract：:The PilF protein from the thermophilic bacterium Thermus thermophilus is a traffic ATPase powering the assembly of the DNA translocation machinery as well as of type 4 pili. Thereby PilF mediates the natural transformability of T. thermophilus. PilF contains a C-terminal ATPase domain and three N-terminal domains with...

journal_title：Biomolecular NMR assignments

authors： Neißner K,Keller H,Duchardt-Ferner E,Hacker C,Kruse K,Averhoff B,Wöhnert J

更新日期：2019-10-01 00:00:00

abstract：:The actin filament dynamics in nematode, Caenorhabditis elegans, is regulated by differential activity of two proteins UNC-60A and UNC-60B. UNC-60A exhibits strong pointed end depolymerization on C. elegans actin (Ce-actin), strong inhibition of polymerization, strong monomer sequestering activity, weak severing activ...

journal_title：Biomolecular NMR assignments

authors： Shukla VK,Kabra A,Yadav R,Ono S,Kumar D,Arora A

更新日期：2015-10-01 00:00:00

abstract：:The regulation and localization of the neuronal voltage gated Ca(2+) channel CaV1.2 is important for synaptic plasticity associated with learning and memory. The cytoskeletal protein, α-actinin-1 is known to interact with CaV1.2 and stabilize its localization at the postsynaptic membrane. Here we report both backbone ...

journal_title：Biomolecular NMR assignments

authors： Turner M,Anderson DE,Rajan S,Hell JW,Ames JB

更新日期：2016-04-01 00:00:00

abstract：:Ras homologue enriched in brain (Rheb) is a small GTPase that plays an important role in tuberous sclerosis. Here we present the backbone assignments of activated rRheb in complex with the non-hydrolisable GTP analogue GppNHp. These assignments now provide a basis for the analysis of rRheb's interaction with putative ...

journal_title：Biomolecular NMR assignments

authors： Schwarten M,Berghaus C,Heumann R,Stoll R

更新日期：2007-07-01 00:00:00

abstract：:The catalytic subunit of protein kinase A is involved with a number of signal transduction pathways and has been used as a benchmark to study the structural biology and biochemistry for the entire kinase family of enzymes. Here, we report the backbone assignment of the intact 41 kDa catalytic subunit bound to AMP-PNP....

journal_title：Biomolecular NMR assignments

authors： Masterson LR,Shi L,Tonelli M,Mascioni A,Mueller MM,Veglia G

更新日期：2009-06-01 00:00:00

abstract：:Tuberculosis is one of the deadliest diseases worldwide affecting approximately 10 million people in 2018. This classifies tuberculosis as epidemic in several countries and leads to an increasing number of multidrug-resistant strains. Thus, the development of new drugs is essential to effective treatments. A potential...

journal_title：Biomolecular NMR assignments

authors： Bartkevihi L,Martins B,de Oliveira DMP,Pires JRM,Anobom CD,Almeida FCL

更新日期：2020-04-01 00:00:00

abstract：:In Northern America and Europe a great number of people are suffering from birch pollen allergy and pollen related food allergies. The trigger for these immunological reactions is the 17.5 kDa major birch pollen allergen Bet v 1, which belongs to the family of PR-10 (pathogenesis-related) proteins. In nature, Bet v 1 ...

journal_title：Biomolecular NMR assignments

authors： Ahammer L,Grutsch S,Wallner M,Ferreira F,Tollinger M

更新日期：2017-10-01 00:00:00

abstract：:Myeloid differentiating factor 88 (MyD88) is one of a critical adaptor molecule in the Toll-like receptor (TLR) signaling pathway. The TIR domain of MyD88 serves as a protein-protein interaction module and interacts with other TIR-containing proteins such as Mal (MyD88 adaptor-like) and Toll-like receptor 4 to form si...

journal_title：Biomolecular NMR assignments

authors： Ohnishi H,Tochio H,Kato Z,Kimura T,Hiroaki H,Kondo N,Shirakawa M

更新日期：2010-10-01 00:00:00

abstract：:We report the nearly complete 1H, 13C and 15N resonance assignments of the oxidized form (Cys(67)-Cys(70)) of the N-terminal domain of PilB from Neisseria meningitidis. Secondary structure determination using CSI method and TALOS leads mainly to the prediction of 7 alpha-helical and 5 beta-sheet parts. ...

journal_title：Biomolecular NMR assignments

authors： Quinternet M,Beaufils C,Neiers F,Tsan P,Boschi-Muller S,Averlant-Petit MC,Branlant G,Cung MT

更新日期：2007-07-01 00:00:00

abstract：:Sulfolobus solfataricus DNA polymerase IV (Dpo4), a prototype Y-family DNA polymerase, contains a unique little finger domain besides a catalytic core. Here, we report the chemical shift assignments for the backbone nitrogens, α and β carbons, and amide protons of the little finger domain of Dpo4. This work and our pu...

journal_title：Biomolecular NMR assignments

authors： Ma D,Fowler JD,Suo Z

更新日期：2011-10-01 00:00:00

abstract：:Q38FZ4 (UniProt accession number), is an 85-residue hypothetical protein from Trypanosoma brucei (T. brucei). Q38FZ4, which might be specific among the trypanosomatid genomes, shares low sequence similarity with mammal proteins and also has an essential function in the growth of T. brucei. Here we report the resonance...

journal_title：Biomolecular NMR assignments

authors： Wang R,Zhang J,Liao S,Tu X

更新日期：2020-10-01 00:00:00

abstract：:E. coli nitroreductase NfsB (also called NfnB) has been studied extensively, largely due to its potential for cancer gene therapy. A homodimeric flavoprotein of 216 residues, it catalyses the reduction of nitroaromatics to cytotoxic hydroxylamines by NADH and NADPH and also the reduction of quinones to hydroxyquinones...

journal_title：Biomolecular NMR assignments

authors： Hyde EI,Chau AK,Smith LJ

更新日期：2021-01-09 00:00:00

abstract：:We report NMR assignments of the protein backbone of the C-terminal domain (163 a.a.) of human class 1 translation termination factor eRF1. It was found that several protein loop residues exist in two slowly interconverting conformational states. ...

journal_title：Biomolecular NMR assignments

authors： Mantsyzov AB,Ivanova EV,Birdsall B,Kolosov PM,Kisselev LL,Polshakov VI

更新日期：2007-12-01 00:00:00

abstract：:TAR RNA binding protein (TRBP) is a double-stranded RNA binding protein involved in various biological processes like cell growth, development, death, etc. The protein exists as two isoforms TRBP2 and TRBP1. TRBP2 contains additional 21 amino acids at its N-terminus, which are proposed to be involved in its membrane l...

journal_title：Biomolecular NMR assignments

authors： Paithankar H,Jadhav PV,Naglekar AS,Sharma S,Chugh J

更新日期：2018-04-01 00:00:00

abstract：:A peptide or a small protein released from an exocrine gland or in urine is utilized as a chemosignal that elicits social or reproductive behavior in mice. Recently, we identified the male-specific peptide, exocrine gland-secreting peptide 1 (ESP1), in mouse tear fluids that enhanced female sexual receptive behavior, ...

journal_title：Biomolecular NMR assignments

authors： Taniguchi M,Yoshinaga S,Haga-Yamanaka S,Touhara K,Terasawa H

更新日期：2014-04-01 00:00:00

abstract：:GNA2132 (Genome-derived Neisseria Antigen 2132) is a surface-exposed lipoprotein discovered by reverse vaccinology and expressed by genetically diverse Neisseria meningitidis strains (Pizza et al. 2000). The protein induces bactericidal antibodies against most strains of Meningococccus and has been included in a multi...

journal_title：Biomolecular NMR assignments

authors： Esposito V,Musi V,Veggi D,Pastore A,Pizza M

更新日期：2010-04-01 00:00:00

abstract：:Translationally-controlled tumor protein (TCTP) is a eukaryote-conserved protein with crucial roles in cellular growth. It has also been proposed that plant TCTP has functions specific to plant, while no structure of TCTP from photosynthetic organism has been reported. Nannochloropsis is a photosynthetic microalga wit...

journal_title：Biomolecular NMR assignments

authors： Yao X,Xiao Y,Cui Q,Feng Y

更新日期：2015-10-01 00:00:00

abstract：:LicT belongs to an essential family of bacterial antitermination proteins which bind to nascent mRNAs in order to stimulate transcription of sugar-metabolizing operons. As most of other antitermination proteins involved in carbohydrate metabolism, LicT is composed of a N-terminal RNA-binding module (CAT) and two homol...

journal_title：Biomolecular NMR assignments

authors： Yang Y,Declerck N,Déméné H

更新日期：2020-04-01 00:00:00

abstract：:Bacterial thiol peroxidases (Tpxs) are antioxidant enzymes which exist in various bacteria. Tpxs reduce the lipid hydroperoxides to protect the membrane lipid from destruction by reactive oxygen species. Tpxs are essential enzymes for bacterial anaerobic growth. Herein, we report the resonance assignments of (1)H, (13...

journal_title：Biomolecular NMR assignments

authors： Lu J,Yang F,Li Y,Xia B,Jin C

更新日期：2008-12-01 00:00:00

abstract：:During its life cycle, the malaria parasite Plasmodium falciparum is found intracellular to human erythrocytes, where its survival and ability to multiply critically depends on the control of the environment redox state. Thioredoxin is a small protein containing 104 amino acids that is part of the parasite specific re...

journal_title：Biomolecular NMR assignments

authors： Munte CE,Becker K,Schirmer RH,Kalbitzer HR

更新日期：2009-12-01 00:00:00

abstract：:S100A15 (koebnerisin) is overexpressed in psoriatic skin and displays distinct localizations in skin and breast with divergent functions in inflammation. Here we report the backbone and side-chain resonance assignments for the Ca(2+)-bound human S100A15. ...

journal_title：Biomolecular NMR assignments

authors： Cho CC,Hung KW,Yu C

更新日期：2014-04-01 00:00:00

abstract：:The peptidoglycan is a major component of the bacterial cell wall and is essential to maintain cellular integrity and cell shape. Penicillin-Binding Proteins (PBPs) catalyze the final biosynthetic steps of peptidoglycan synthesis from lipid II precursor and are the main targets of β-lactam antibiotics. The molecular d...

journal_title：Biomolecular NMR assignments

authors： Jean NL,Bougault C,Derouaux A,Callens G,Vollmer W,Simorre JP

更新日期：2015-04-01 00:00:00

abstract：:The replication of the hepatitis B virus is initiated by binding of the viral reverse transcriptase protein complex to the apical stem loop of the epsilon element to place it next to the primer loop, from which a four nucleotide DNA primer is subsequently synthesized. Here, we present the (1)H/(13)C/(15)N NMR assignme...

journal_title：Biomolecular NMR assignments

authors： van der Werf RM,Girard FC,Nelissen F,Tessari M,Wijmenga SS

更新日期：2008-12-01 00:00:00

abstract：:TraI, the F plasmid-encoded nickase, is a 1,756 amino acid protein essential for conjugative transfer of F plasmid DNA from one bacterium to another. While crystal structures of N- and C-terminal domains of F TraI have been determined, central domains of the protein are structurally unexplored. These middle domains (b...

journal_title：Biomolecular NMR assignments

authors： Wright NT,Majumdar A,Schildbach JF

更新日期：2011-04-01 00:00:00

abstract：:Norovirus protease cleaves the virus-encoded polyprotein into six mature nonstructural proteins, presenting itself as an essential enzyme for the viral replication as well as an attractive target for the antiviral drug development. A deeper understanding of the structural mechanism of the protease-substrates/inhibitor...

journal_title：Biomolecular NMR assignments

authors： Takahashi D,Kim Y,Chang KO,Anbanandam A,Prakash O

更新日期：2012-04-01 00:00:00

abstract：:Nearly complete backbone resonance assignments for the 357 residue, 42 kDa enzyme arginine kinase in a transition state analogue (TSA) complex are presented. The TSA is a quaternary complex of arginine kinase, MgADP, arginine, and nitrate. About 93% (320 of 344) of the non-proline backbone amides were assigned using a...

journal_title：Biomolecular NMR assignments

authors： Davulcu O,Niu X,Brüschweiler-Li L,Brüschweiler R,Skalicky JJ,Chapman MS

更新日期：2014-10-01 00:00:00

abstract：:Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen and a primary cause of infection in humans. P. aeruginosa can acquire resistance against multiple groups of antimicrobial agents, including β-lactams, aminoglycosides and fluoroquinolones, and multidrug resistance is increasing in this organism which mak...

journal_title：Biomolecular NMR assignments

authors： Bernal A,Hu Y,Palmer SO,Silva A,Bullard J,Zhang Y

更新日期：2016-10-01 00:00:00

abstract：:Tensin is an important cytoplasmic phosphoprotein localized to integrin-mediated focal adhesion. It links actin cytoskeleton to extracellular matrix through its N-terminal actin-binding domain and C-terminal phosphotyrosine-binding domain. Studies of knockout mice revealed the critical roles of tensin in skeletal musc...

journal_title：Biomolecular NMR assignments

authors： Chen L,Liu C,Rui F,Zhu G

更新日期：2011-10-01 00:00:00

abstract：:Translation initiation factor 3 (IF3) is one of the three protein factors that bind to the small ribosomal subunit and it is required for the initiation of protein biosynthesis in bacteria. IF3 contains two independent domains, N- and C-terminal domains, which are connected by a lysine-rich interdomain linker. IF3 und...

journal_title：Biomolecular NMR assignments

authors： Li L,Palmer SO,Gomez EA,Mendiola F,Wang T,Bullard JM,Zhang Y

更新日期：2020-04-01 00:00:00