NMR assignments of the C-terminal domain of human polypeptide release factor eRF1.

abstract：:Light chain (AL) amyloidosis is a systemic disease characterized by the formation of immunoglobulin light-chain fibrils in critical organs of the body. The light-chain protein AL-09 presents one severe case of cardiac AL amyloidosis, which contains seven mutations in the variable domain (VL) relative to its germline c...

journal_title：Biomolecular NMR assignments

authors： Piehl DW,Blancas-Mejía LM,Ramirez-Alvarado M,Rienstra CM

更新日期：2017-04-01 00:00:00

abstract：:Phosphoenolpyruvate binding to the C-terminal domain (EIC) of enzyme I of the bacterial phosphotransferase system (PTS) initiates a phosphorylation cascade that results in sugar translocation across the cell membrane and controls a large number of essential pathways in bacterial metabolism. EIC undergoes an expanded t...

journal_title：Biomolecular NMR assignments

authors： Dotas RR,Venditti V

更新日期：2018-04-01 00:00:00

abstract：:In Europe, Northern America, and China a large number of individuals are suffering from peach (Prunus persica) allergy caused by the protein Pru p 1. Immunologic reactions against this 17.5 kDa protein result from initial sensitization to the birch (Betula verrucosa) pollen allergen Bet v 1 and subsequent immunologic ...

journal_title：Biomolecular NMR assignments

authors： Führer S,Trimmel S,Breuker K,Tollinger M

更新日期：2019-04-01 00:00:00

abstract：:The Breast Cancer susceptibility protein 2 (BRCA2) is involved in mechanisms that maintain genome stability, including DNA repair, replication and cell division. These functions are ensured by the folded C-terminal DNA binding domain of BRCA2 but also by its large regions predicted to be disordered. Several studies ha...

journal_title：Biomolecular NMR assignments

authors： Julien M,Miron S,Carreira A,Theillet FX,Zinn-Justin S

更新日期：2020-04-01 00:00:00

abstract：:Sulfolobus solfataricus DNA polymerase IV (Dpo4), a prototype Y-family DNA polymerase, contains a unique little finger domain besides a catalytic core. Here, we report the chemical shift assignments for the backbone nitrogens, α and β carbons, and amide protons of the little finger domain of Dpo4. This work and our pu...

journal_title：Biomolecular NMR assignments

authors： Ma D,Fowler JD,Suo Z

更新日期：2011-10-01 00:00:00

abstract：:Immunoglobulin E (IgE) plays a central role in allergic reactions. IgE is a dynamic molecule that is capable of undergoing large conformational changes. X-ray crystal structures of the Fc region of IgE in complex with various ligands have shown that IgE-Fc can exist in extended and various bent conformations. IgE-Fc c...

journal_title：Biomolecular NMR assignments

authors： Benjamin SV,Creeke PI,Henry AJ,McDonnell JM

更新日期：2020-04-01 00:00:00

abstract：:LicT belongs to an essential family of bacterial antitermination proteins which bind to nascent mRNAs in order to stimulate transcription of sugar-metabolizing operons. As most of other antitermination proteins involved in carbohydrate metabolism, LicT is composed of a N-terminal RNA-binding module (CAT) and two homol...

journal_title：Biomolecular NMR assignments

authors： Yang Y,Declerck N,Déméné H

更新日期：2020-04-01 00:00:00

abstract：:The PilF protein from the thermophilic bacterium Thermus thermophilus is a traffic ATPase powering the assembly of the DNA translocation machinery as well as of type 4 pili. Thereby PilF mediates the natural transformability of T. thermophilus. PilF contains a C-terminal ATPase domain and three N-terminal domains with...

journal_title：Biomolecular NMR assignments

authors： Neißner K,Keller H,Duchardt-Ferner E,Hacker C,Kruse K,Averhoff B,Wöhnert J

更新日期：2019-10-01 00:00:00

abstract：:As part of our NMR structure determination of the Human S100A1, we report nearly complete NMR chemical shift assignments for the (1)H, (13)C and (15)N nuclei. ...

journal_title：Biomolecular NMR assignments

authors： Gupta AA,Mohan SK,Chin Y

更新日期：2012-10-01 00:00:00

abstract：:Nervous necrosis virus (NNV) is a non-enveloped virus that causes massive mortality in aquaculture fish production worldwide. Recently X-ray crystallography and single particle cryo-EM have independently determined the icosahedral capsid of NNV to near-atomic resolutions to show the capsid protein is composed of a S-d...

journal_title：Biomolecular NMR assignments

authors： Štěrbová P,Wu D,Lou YC,Wang CH,Chang WH,Tzou DM

更新日期：2020-04-01 00:00:00

abstract：:A pheromone-binding protein from navel orange worm, Amyelois transitella (Atra-PBP1) binds to non-polar pheromone molecules and facilitates the transport and delivery of pheromone to the membrane-bound pheromone receptors. We report complete NMR chemical shift assignments of Atra-PBP1 obtained at pH 4.5 and 25 degrees...

journal_title：Biomolecular NMR assignments

authors： Xu X,Li Y,Rayo J,Ishida Y,Leal W,Ames JB

更新日期：2008-12-01 00:00:00

abstract：:Arsenate reductases (ArsC) are a group of enzymes that play essential roles in biological arsenic detoxification pathways by catalyzing the intracellular reduction of arsenate to arsenite, which is subsequently extruded from the cells by specific transport systems. The ArsC protein from cyanobacterium Synechocystis sp...

journal_title：Biomolecular NMR assignments

authors： Yu C,Xia B,Jin C

更新日期：2011-04-01 00:00:00

abstract：:The protein dimethyladenosine transferase 1 (Dim1) is a highly conserved protein occurring in organisms ranging from bacteria such as E. coli where it is named KsgA to humans. Since Dim1 is involved in the biogenesis of the small ribosomal subunit it is an essential protein. During ribosome biogenesis Dim1 acts as an ...

journal_title：Biomolecular NMR assignments

authors： Kaiser M,Hacker C,Duchardt-Ferner E,Wöhnert J

更新日期：2019-10-01 00:00:00

abstract：:Human voltage-gated sodium (NaV) channels are critical for initiating and propagating action potentials in excitable cells. Nine isoforms have different roles but similar topologies, with a pore-forming α-subunit and auxiliary transmembrane β-subunits. NaV pathologies lead to debilitating conditions including epilepsy...

journal_title：Biomolecular NMR assignments

authors： Isbell HM,Kilpatrick AM,Lin Z,Mahling R,Shea MA

更新日期：2018-10-01 00:00:00

abstract：:Nuclear Factor κB (NF-κB) is a family of five related transcription factors that recognize a κB DNA element on the promoter and enhancer regions of target genes and modulate their expression. Here we report a complete set of 1H, 13C, 15N backbone and side chain resonance assignments for the p50 DNA binding and dimeriz...

journal_title：Biomolecular NMR assignments

authors： Singh A,Dyson HJ

更新日期：2020-09-16 00:00:00

abstract：:The peptidoglycan is a major component of the bacterial cell wall and is essential to maintain cellular integrity and cell shape. Penicillin-Binding Proteins (PBPs) catalyze the final biosynthetic steps of peptidoglycan synthesis from lipid II precursor and are the main targets of β-lactam antibiotics. The molecular d...

journal_title：Biomolecular NMR assignments

authors： Jean NL,Bougault C,Derouaux A,Callens G,Vollmer W,Simorre JP

更新日期：2015-04-01 00:00:00

abstract：:Tensin is an important cytoplasmic phosphoprotein localized to integrin-mediated focal adhesion. It links actin cytoskeleton to extracellular matrix through its N-terminal actin-binding domain and C-terminal phosphotyrosine-binding domain. Studies of knockout mice revealed the critical roles of tensin in skeletal musc...

journal_title：Biomolecular NMR assignments

authors： Chen L,Liu C,Rui F,Zhu G

更新日期：2011-10-01 00:00:00

abstract：:RegB is involved in the control of the phage T4 life cycle. It inactivates the phage early mRNAs when their translation is no more required. We determined its structure and identified residues involved in substrate binding. For this, all backbone and 90% of side-chain resonance frequencies were assigned. ...

journal_title：Biomolecular NMR assignments

authors： Odaert B,Saïda F,Bontems F

更新日期：2007-07-01 00:00:00

abstract：:Ubiquitin Specific Protease 25 (USP25), a member of the deubiquitinase family, is involved in several disease-related signal pathways including myogenesis, immunity and protein degradation. It specially catalyzes the hydrolysis of the K48-linked and K63-linked polyubiquitin chains. USP25 contains one ubiquitin-associa...

journal_title：Biomolecular NMR assignments

authors： Shi L,Wen Y,Zhang N

更新日期：2014-10-01 00:00:00

abstract：:During its life cycle, the malaria parasite Plasmodium falciparum is found intracellular to human erythrocytes, where its survival and ability to multiply critically depends on the control of the environment redox state. Thioredoxin is a small protein containing 104 amino acids that is part of the parasite specific re...

journal_title：Biomolecular NMR assignments

authors： Munte CE,Becker K,Schirmer RH,Kalbitzer HR

更新日期：2009-12-01 00:00:00

abstract：:Galectins recognize β-galectosides to promote a variety of cellular functions. Despite their sequence variations, all galectins share the same carbohydrate recognition domains (CRD) and their modes of ligand recognition at a structural level are essentially identical. Human galectin 8 plays an important role in numero...

journal_title：Biomolecular NMR assignments

authors： Liu CH,Chien CT,Lin CH,Hsu ST

更新日期：2015-10-01 00:00:00

abstract：:Phosphoethanolamine methyltransferases (PMTs also known as PEAMTs) catalyze the three-step s-adenosyl-methionione-dependent methylation of phosphoethanolamine to form phosphocholine. These enzymes play an important function in the synthesis of phosphatidylcholine, the major phospholipid in the membranes of lower and h...

journal_title：Biomolecular NMR assignments

authors： Bezsonova I,Rujan I,Bobenchik AM,Gorbatyuk V,Maciejewski MW,Gorbatyuk O,Hao B,Arthanari H,Mamoun CB,Hoch JC

更新日期：2013-04-01 00:00:00

abstract：:The catalytic subunit of protein kinase A is involved with a number of signal transduction pathways and has been used as a benchmark to study the structural biology and biochemistry for the entire kinase family of enzymes. Here, we report the backbone assignment of the intact 41 kDa catalytic subunit bound to AMP-PNP....

journal_title：Biomolecular NMR assignments

authors： Masterson LR,Shi L,Tonelli M,Mascioni A,Mueller MM,Veglia G

更新日期：2009-06-01 00:00:00

abstract：:Plasmodium falciparum is responsible for causing cerebral malaria in humans. IMP1 is an immunogenic protein, present in the parasite, which has been shown to induce an immune response against apicomplexan parasites in a species-specific manner. Here, we report the complete NMR assignments of PfIMP1. ...

journal_title：Biomolecular NMR assignments

authors： Benjamin S,Williams F,Kerry L,Matthews S

更新日期：2015-10-01 00:00:00

abstract：:The gelation factor from Dictyostelium discoideum (ABP-120) is an actin binding protein consisting of six immunoglobulin (Ig) domains in the C-terminal rod domain. We have recently used the pair of domains 5 and 6 of ABP-120 as a model system for studying multi-domain nascent chain folding on the ribosome. Here we pre...

journal_title：Biomolecular NMR assignments

authors： Hsu ST,Cabrita LD,Christodoulou J,Dobson CM

更新日期：2009-06-01 00:00:00

abstract：:The homeobox gene (HOXA13) codes for a transcription factor protein that binds to AT-rich DNA sequences and controls expression of many important proteins during embryonic morphogenesis. We report complete NMR chemical shift assignments of the mouse HOXA13 DNA binding domain (A13DBD; BMRB no. 16252). ...

journal_title：Biomolecular NMR assignments

authors： Zhang Y,Thornburg CK,Stadler HS,Ames JB

更新日期：2009-12-01 00:00:00

abstract：:Ebola viral infections have resulted in several deadly epidemics in recent years in West and Central Africa. Because only one of the seven proteins encoded by the viral genome possesses enzymatic activity, disruption of protein-protein interactions is a promising route for antiviral drug development. We carried out a ...

journal_title：Biomolecular NMR assignments

authors： Lee W,Tonelli M,Wu C,Aceti DJ,Amarasinghe GK,Markley JL

更新日期：2019-10-01 00:00:00

abstract：:Tuberculosis is one of the deadliest diseases worldwide affecting approximately 10 million people in 2018. This classifies tuberculosis as epidemic in several countries and leads to an increasing number of multidrug-resistant strains. Thus, the development of new drugs is essential to effective treatments. A potential...

journal_title：Biomolecular NMR assignments

authors： Bartkevihi L,Martins B,de Oliveira DMP,Pires JRM,Anobom CD,Almeida FCL

更新日期：2020-04-01 00:00:00

abstract：:Cohesin and dockerin domains are critical assembling components of cellulosome, a large extracellular multienzyme complex which is used by anaerobic cellulolytic bacteria to efficiently degrade lignocellulose. According to sequence homology, cohesins can be divided into three major groups, whereas cohesins from Clostr...

journal_title：Biomolecular NMR assignments

authors： Cui Z,Li Y,Xiao Y,Feng Y,Cui Q

更新日期：2013-04-01 00:00:00

abstract：:Translationally-controlled tumor protein (TCTP) is a eukaryote-conserved protein with crucial roles in cellular growth. It has also been proposed that plant TCTP has functions specific to plant, while no structure of TCTP from photosynthetic organism has been reported. Nannochloropsis is a photosynthetic microalga wit...

journal_title：Biomolecular NMR assignments

authors： Yao X,Xiao Y,Cui Q,Feng Y

更新日期：2015-10-01 00:00:00