(1)H, (13)C, and (15)N chemical shift assignments for PfPMT, a phosphoethanolamine methyltransferase from Plasmodium falciparum.

abstract：:PRK1 is a member of the protein kinase C-related kinase (PRK) family of serine/threonine kinases and a downstream effector of Rho GTPases. PRK1 has three N-terminal Homology Region 1 (HR1) domains (HR1a, HR1b and HR1c), which form antiparallel coiled coils that interact with Rho family GTPases. PRK1 also has a C2-like...

journal_title：Biomolecular NMR assignments

authors： Sophocleous G,Wood G,Owen D,Mott HR

更新日期：2020-10-01 00:00:00

abstract：:The gelation factor from Dictyostelium discoideum (ABP-120) is an actin binding protein consisting of six immunoglobulin (Ig) domains in the C-terminal rod domain. We have recently used the pair of domains 5 and 6 of ABP-120 as a model system for studying multi-domain nascent chain folding on the ribosome. Here we pre...

journal_title：Biomolecular NMR assignments

authors： Hsu ST,Cabrita LD,Christodoulou J,Dobson CM

更新日期：2009-06-01 00:00:00

abstract：:TraI, the F plasmid-encoded nickase, is a 1,756 amino acid protein essential for conjugative transfer of F plasmid DNA from one bacterium to another. While crystal structures of N- and C-terminal domains of F TraI have been determined, central domains of the protein are structurally unexplored. These middle domains (b...

journal_title：Biomolecular NMR assignments

authors： Wright NT,Majumdar A,Schildbach JF

更新日期：2011-04-01 00:00:00

abstract：:The apo-form of the 21.4 kDa catalytic domain and the 10.7 kDa carbohydrate binding domain of the AA10 family lytic polysaccharide monooxygenase ScLPMO10C from Streptomyces coelicolor have been isotopically labeled and recombinantly expressed in Escherichia coli. In this paper, we report the 1H, 13C, and 15N chemical ...

journal_title：Biomolecular NMR assignments

authors： Courtade G,Forsberg Z,Vaaje-Kolstad G,Eijsink VGH,Aachmann FL

更新日期：2017-10-01 00:00:00

abstract：:Bacterial thiol peroxidases (Tpxs) are antioxidant enzymes which exist in various bacteria. Tpxs reduce the lipid hydroperoxides to protect the membrane lipid from destruction by reactive oxygen species. Tpxs are essential enzymes for bacterial anaerobic growth. Herein, we report the resonance assignments of (1)H, (13...

journal_title：Biomolecular NMR assignments

authors： Lu J,Yang F,Li Y,Xia B,Jin C

更新日期：2008-12-01 00:00:00

abstract：:Salmonella typhimurium OppA is the periplasmic oligopeptide-binding protein. Backbone resonances of OppA(D419N) on its own were assigned for approximately 90% of residues. Missing residues are localised around the ligand-binding site, suggesting conformational flexibility in the unliganded state. ...

journal_title：Biomolecular NMR assignments

authors： Kurashima-Ito K,Moromisato K,Nishimura K,Wälchli M,Tame JR,Ito Y

更新日期：2007-07-01 00:00:00

abstract：:The agglutinin-like-sequence (ALS) family of adhesion proteins are a key virulence factor for C. albicans. These proteins have been implicated in several functions, notably adhesion and invasion of different cell types, as well as binding to peptides and proteins in the cell surface and extracellular matrix. In order ...

journal_title：Biomolecular NMR assignments

authors： Yan R,Simpson PJ,Matthews SJ,Cota E

更新日期：2010-10-01 00:00:00

abstract：:The cDNA of UVI31+ was cloned from C. reinhardtii and expressed in E. coli from where the protein was purified to homogeneity. The purified protein exhibited beta-lactamase activity (Manuscript in preparation). However, UVI31+ has no homology with the known β-lactamases. In order to understand the structural basis of ...

journal_title：Biomolecular NMR assignments

authors： Rout AK,Minda R,Peri D,Ramakrishnan V,Bhattacharjee SK,Rao BJ,Chary KV

更新日期：2010-10-01 00:00:00

abstract：:Parkinson's disease (PD) is a chronic, progressive neurodegenerative disease, where dopaminergic cells die most prominently in the area of substantia nigra. Neurotrophic factors (NTFs) are secreted proteins, which upon binding to their target receptors trigger survival pathways to prevent neuronal loss. Recently disco...

journal_title：Biomolecular NMR assignments

authors： Hellman M,Peränen J,Saarma M,Permi P

更新日期：2010-10-01 00:00:00

abstract：:Phosphoenolpyruvate binding to the C-terminal domain (EIC) of enzyme I of the bacterial phosphotransferase system (PTS) initiates a phosphorylation cascade that results in sugar translocation across the cell membrane and controls a large number of essential pathways in bacterial metabolism. EIC undergoes an expanded t...

journal_title：Biomolecular NMR assignments

authors： Dotas RR,Venditti V

更新日期：2018-04-01 00:00:00

abstract：:The regulation and localization of the neuronal voltage gated Ca(2+) channel CaV1.2 is important for synaptic plasticity associated with learning and memory. The cytoskeletal protein, α-actinin-1 is known to interact with CaV1.2 and stabilize its localization at the postsynaptic membrane. Here we report both backbone ...

journal_title：Biomolecular NMR assignments

authors： Turner M,Anderson DE,Rajan S,Hell JW,Ames JB

更新日期：2016-04-01 00:00:00

abstract：:Repressor of primer (Rop, or ROM, RNA I modulator) is a 63 amino acid four-helix bundle protein that exists in solution as an anti-parallel homodimer. This protein has been extensively studied, including by X-ray crystallography, NMR, rational design, and combinatorial mutagenesis. Previous NMR experiments with wild-t...

journal_title：Biomolecular NMR assignments

authors： Bowles DP,Yuan C,Stephany KR,Lavinder JJ,Hansen AL,Magliery TJ

更新日期：2018-10-01 00:00:00

abstract：:The bacterium Geobacter metallireducens is capable of transferring electrons to the cell exterior, a process designated extracellular electron transfer. This mechanism allows the microorganism to reduce extracellular acceptors such as Fe(III) (hydr)oxides and water toxic and/or radioactive contaminants including Cr(VI...

journal_title：Biomolecular NMR assignments

authors： Portela PC,Dantas JM,Salgueiro CA

更新日期：2020-04-01 00:00:00

abstract：:Early response to dehydration 10 protein (ERD10) is an intrinsically disordered protein from Arabidopsis thaliana. The protein is upregulated during stress however its mechanism of action at atomic level is not well understood. In the present work multidimensional NMR methodologies are used in order to facilitate the ...

journal_title：Biomolecular NMR assignments

authors： Cedeño C,Żerko S,Tompa P,Koźmiński W

更新日期：2017-10-01 00:00:00

abstract：:The Src tyrosine kinase is the paradigm of an oncogenic kinase, and of regulation by intramolecular inhibitory interactions, as well as an important anticancer target due to its roles in cell proliferation and metastasis. The assignment of backbone (1)H(N), (13)C(α), (13)CO, and (15)N, and sidechain (13)C(β) resonance...

journal_title：Biomolecular NMR assignments

authors： Campos-Olivas R,Marenchino M,Scapozza L,Gervasio FL

更新日期：2011-10-01 00:00:00

abstract：:Fibroblast growth factor receptor (FGFR) 4 has been associated with progression of melanoma, breast, head and neck and hepatocellular carcinoma and is therefore an interesting target for therapeutic intervention (Ho et al. in J Hepatol 50:118-127, 2009). The extracellular D2 domain of the FGFR4 receptor contains a hep...

journal_title：Biomolecular NMR assignments

authors： Elshorst B,Saxena K,Schieborr U,Schwalbe H

更新日期：2013-10-01 00:00:00

abstract：:The S100 family belongs to the EF-hand calcium-binding proteins regulating a wide range of important cellular processes via protein-protein interactions. Most S100 proteins adopt a conformation of non-covalent homodimer for their functions. Calcium binding to the EF-hand motifs of S100 proteins is essential for trigge...

journal_title：Biomolecular NMR assignments

authors： Hung KW,Chang YM,Yu C

更新日期：2013-10-01 00:00:00

abstract：:Myeloid differentiating factor 88 (MyD88) is one of a critical adaptor molecule in the Toll-like receptor (TLR) signaling pathway. The TIR domain of MyD88 serves as a protein-protein interaction module and interacts with other TIR-containing proteins such as Mal (MyD88 adaptor-like) and Toll-like receptor 4 to form si...

journal_title：Biomolecular NMR assignments

authors： Ohnishi H,Tochio H,Kato Z,Kimura T,Hiroaki H,Kondo N,Shirakawa M

更新日期：2010-10-01 00:00:00

abstract：:Immunoglobulin E (IgE) plays a central role in allergic reactions. IgE is a dynamic molecule that is capable of undergoing large conformational changes. X-ray crystal structures of the Fc region of IgE in complex with various ligands have shown that IgE-Fc can exist in extended and various bent conformations. IgE-Fc c...

journal_title：Biomolecular NMR assignments

authors： Benjamin SV,Creeke PI,Henry AJ,McDonnell JM

更新日期：2020-04-01 00:00:00

abstract：:The actin filament dynamics in nematode, Caenorhabditis elegans, is regulated by differential activity of two proteins UNC-60A and UNC-60B. UNC-60A exhibits strong pointed end depolymerization on C. elegans actin (Ce-actin), strong inhibition of polymerization, strong monomer sequestering activity, weak severing activ...

journal_title：Biomolecular NMR assignments

authors： Shukla VK,Kabra A,Yadav R,Ono S,Kumar D,Arora A

更新日期：2015-10-01 00:00:00

abstract：:Ebola viral infections have resulted in several deadly epidemics in recent years in West and Central Africa. Because only one of the seven proteins encoded by the viral genome possesses enzymatic activity, disruption of protein-protein interactions is a promising route for antiviral drug development. We carried out a ...

journal_title：Biomolecular NMR assignments

authors： Lee W,Tonelli M,Wu C,Aceti DJ,Amarasinghe GK,Markley JL

更新日期：2019-10-01 00:00:00

abstract：:Cohesin and dockerin domains are critical assembling components of cellulosome, a large extracellular multienzyme complex which is used by anaerobic cellulolytic bacteria to efficiently degrade lignocellulose. According to sequence homology, cohesins can be divided into three major groups, whereas cohesins from Clostr...

journal_title：Biomolecular NMR assignments

authors： Cui Z,Li Y,Xiao Y,Feng Y,Cui Q

更新日期：2013-04-01 00:00:00

abstract：:Nearly complete backbone resonance assignments for the 357 residue, 42 kDa enzyme arginine kinase in a transition state analogue (TSA) complex are presented. The TSA is a quaternary complex of arginine kinase, MgADP, arginine, and nitrate. About 93% (320 of 344) of the non-proline backbone amides were assigned using a...

journal_title：Biomolecular NMR assignments

authors： Davulcu O,Niu X,Brüschweiler-Li L,Brüschweiler R,Skalicky JJ,Chapman MS

更新日期：2014-10-01 00:00:00

abstract：:Translation initiation factor 3 (IF3) is one of the three protein factors that bind to the small ribosomal subunit and it is required for the initiation of protein biosynthesis in bacteria. IF3 contains two independent domains, N- and C-terminal domains, which are connected by a lysine-rich interdomain linker. IF3 und...

journal_title：Biomolecular NMR assignments

authors： Li L,Palmer SO,Gomez EA,Mendiola F,Wang T,Bullard JM,Zhang Y

更新日期：2020-04-01 00:00:00

abstract：:The C-terminally truncated Y145Stop variant of prion protein (PrP23-144) has been linked to a heritable prionopathy in humans and is also capable of triggering a transmissible prion disease in mice. PrP23-144 can be converted from soluble monomeric form to amyloid under physiological conditions, providing an in vitro ...

journal_title：Biomolecular NMR assignments

authors： Dao HH,Hlaing MZ,Ma Y,Surewicz K,Surewicz WK,Jaroniec CP

更新日期：2020-10-29 00:00:00

abstract：:The peptidoglycan is a major component of the bacterial cell wall and is essential to maintain cellular integrity and cell shape. Penicillin-Binding Proteins (PBPs) catalyze the final biosynthetic steps of peptidoglycan synthesis from lipid II precursor and are the main targets of β-lactam antibiotics. The molecular d...

journal_title：Biomolecular NMR assignments

authors： Jean NL,Bougault C,Derouaux A,Callens G,Vollmer W,Simorre JP

更新日期：2015-04-01 00:00:00

abstract：:Nervous necrosis virus (NNV) is a non-enveloped virus that causes massive mortality in aquaculture fish production worldwide. Recently X-ray crystallography and single particle cryo-EM have independently determined the icosahedral capsid of NNV to near-atomic resolutions to show the capsid protein is composed of a S-d...

journal_title：Biomolecular NMR assignments

authors： Štěrbová P,Wu D,Lou YC,Wang CH,Chang WH,Tzou DM

更新日期：2020-04-01 00:00:00

abstract：:A pheromone-binding protein from navel orange worm, Amyelois transitella (Atra-PBP1) binds to non-polar pheromone molecules and facilitates the transport and delivery of pheromone to the membrane-bound pheromone receptors. We report complete NMR chemical shift assignments of Atra-PBP1 obtained at pH 4.5 and 25 degrees...

journal_title：Biomolecular NMR assignments

authors： Xu X,Li Y,Rayo J,Ishida Y,Leal W,Ames JB

更新日期：2008-12-01 00:00:00

abstract：:Sulfolobus solfataricus DNA polymerase IV (Dpo4), a prototype Y-family DNA polymerase, contains a unique little finger domain besides a catalytic core. Here, we report the chemical shift assignments for the backbone nitrogens, α and β carbons, and amide protons of the little finger domain of Dpo4. This work and our pu...

journal_title：Biomolecular NMR assignments

authors： Ma D,Fowler JD,Suo Z

更新日期：2011-10-01 00:00:00

abstract：:ITCH (aka Atrophin-1-interacting protein 4) is a prominent member of the NEDD4 HECT (Homologous to E6AP C-Terminus) E3 ubiquitin ligase family that regulates numerous cellular functions including inflammatory responses through T-cell activation, cell differentiation, and apoptosis. Known intracellular targets of ITCH-...

journal_title：Biomolecular NMR assignments

authors： Beasley SA,Bardhi R,Spratt DE

更新日期：2019-04-01 00:00:00