Abstract:
:The agglutinin-like-sequence (ALS) family of adhesion proteins are a key virulence factor for C. albicans. These proteins have been implicated in several functions, notably adhesion and invasion of different cell types, as well as binding to peptides and proteins in the cell surface and extracellular matrix. In order to understand their binding mechanism and en route to a full structural determination by NMR, here we report the resonance assignments of backbone atoms plus Ile, Leu and Val methyls for residues 18-329 of ALS1, which comprises the 33.5 kDa binding domain.
journal_name
Biomol NMR Assignjournal_title
Biomolecular NMR assignmentsauthors
Yan R,Simpson PJ,Matthews SJ,Cota Edoi
10.1007/s12104-010-9243-8subject
Has Abstractpub_date
2010-10-01 00:00:00pages
187-90issue
2eissn
1874-2718issn
1874-270Xjournal_volume
4pub_type
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