1H, 13C, and 15N backbone, side-chain, and heme chemical shift assignments for oxidized and reduced forms of the monoheme c-type cytochrome ApcA isolated from the acidophilic metal-reducing bacterium Acidiphilium cryptum.

abstract：:Q38FZ4 (UniProt accession number), is an 85-residue hypothetical protein from Trypanosoma brucei (T. brucei). Q38FZ4, which might be specific among the trypanosomatid genomes, shares low sequence similarity with mammal proteins and also has an essential function in the growth of T. brucei. Here we report the resonance...

journal_title：Biomolecular NMR assignments

authors： Wang R,Zhang J,Liao S,Tu X

更新日期：2020-10-01 00:00:00

abstract：:We present the backbone and sidechain NMR assignments and a structural analysis of the 178-residue wild-type γS-crystallin and the cataract-related point mutant, γS-G18V. γS-crystallin is a structural component of the eye lens, which maintains its solubility and stability over many years. NMR assignments and continued...

journal_title：Biomolecular NMR assignments

authors： Brubaker WD,Martin RW

更新日期：2012-04-01 00:00:00

abstract：:The mitochondrial antiviral signalling protein (MAVS) is a central signal transduction hub in the innate immune response against viral infections. Viral RNA present in the cytoplasm is detected by retinoic acid inducible gene I like receptors, which then activate MAVS via heterotypic interactions between their respect...

journal_title：Biomolecular NMR assignments

authors： He L,Lührs T,Ritter C

更新日期：2015-10-01 00:00:00

abstract：:E. coli nitroreductase NfsB (also called NfnB) has been studied extensively, largely due to its potential for cancer gene therapy. A homodimeric flavoprotein of 216 residues, it catalyses the reduction of nitroaromatics to cytotoxic hydroxylamines by NADH and NADPH and also the reduction of quinones to hydroxyquinones...

journal_title：Biomolecular NMR assignments

authors： Hyde EI,Chau AK,Smith LJ

更新日期：2021-01-09 00:00:00

abstract：:A peptide or a small protein released from an exocrine gland or in urine is utilized as a chemosignal that elicits social or reproductive behavior in mice. Recently, we identified the male-specific peptide, exocrine gland-secreting peptide 1 (ESP1), in mouse tear fluids that enhanced female sexual receptive behavior, ...

journal_title：Biomolecular NMR assignments

authors： Taniguchi M,Yoshinaga S,Haga-Yamanaka S,Touhara K,Terasawa H

更新日期：2014-04-01 00:00:00

abstract：:Myeloid differentiating factor 88 (MyD88) is one of a critical adaptor molecule in the Toll-like receptor (TLR) signaling pathway. The TIR domain of MyD88 serves as a protein-protein interaction module and interacts with other TIR-containing proteins such as Mal (MyD88 adaptor-like) and Toll-like receptor 4 to form si...

journal_title：Biomolecular NMR assignments

authors： Ohnishi H,Tochio H,Kato Z,Kimura T,Hiroaki H,Kondo N,Shirakawa M

更新日期：2010-10-01 00:00:00

abstract：:The cDNA of UVI31+ was cloned from C. reinhardtii and expressed in E. coli from where the protein was purified to homogeneity. The purified protein exhibited beta-lactamase activity (Manuscript in preparation). However, UVI31+ has no homology with the known β-lactamases. In order to understand the structural basis of ...

journal_title：Biomolecular NMR assignments

authors： Rout AK,Minda R,Peri D,Ramakrishnan V,Bhattacharjee SK,Rao BJ,Chary KV

更新日期：2010-10-01 00:00:00

abstract：:In Europe, Northern America, and China a large number of individuals are suffering from peach (Prunus persica) allergy caused by the protein Pru p 1. Immunologic reactions against this 17.5 kDa protein result from initial sensitization to the birch (Betula verrucosa) pollen allergen Bet v 1 and subsequent immunologic ...

journal_title：Biomolecular NMR assignments

authors： Führer S,Trimmel S,Breuker K,Tollinger M

更新日期：2019-04-01 00:00:00

abstract：:YbeA is a 3-methylpseudoridine methyltransferase from Escherichia coli that forms a stable homodimer in solution. It is one of the deeply trefoil 31 knotted proteins, of which the knot encompasses the C-terminal helix that threads through a long loop. Recent studies on the knotted protein folding pathways using YbeA h...

journal_title：Biomolecular NMR assignments

authors： Hsieh SJ,Mallam AL,Jackson SE,Hsu ST

更新日期：2014-10-01 00:00:00

abstract：:ITCH (aka Atrophin-1-interacting protein 4) is a prominent member of the NEDD4 HECT (Homologous to E6AP C-Terminus) E3 ubiquitin ligase family that regulates numerous cellular functions including inflammatory responses through T-cell activation, cell differentiation, and apoptosis. Known intracellular targets of ITCH-...

journal_title：Biomolecular NMR assignments

authors： Beasley SA,Bardhi R,Spratt DE

更新日期：2019-04-01 00:00:00

abstract：:Norovirus protease cleaves the virus-encoded polyprotein into six mature nonstructural proteins, presenting itself as an essential enzyme for the viral replication as well as an attractive target for the antiviral drug development. A deeper understanding of the structural mechanism of the protease-substrates/inhibitor...

journal_title：Biomolecular NMR assignments

authors： Takahashi D,Kim Y,Chang KO,Anbanandam A,Prakash O

更新日期：2012-04-01 00:00:00

abstract：:Human voltage-gated sodium (NaV) channels are critical for initiating and propagating action potentials in excitable cells. Nine isoforms have different roles but similar topologies, with a pore-forming α-subunit and auxiliary transmembrane β-subunits. NaV pathologies lead to debilitating conditions including epilepsy...

journal_title：Biomolecular NMR assignments

authors： Isbell HM,Kilpatrick AM,Lin Z,Mahling R,Shea MA

更新日期：2018-10-01 00:00:00

abstract：:The A. thaliana RCD1 (radical-induced cell death1) protein is a cellular signaling hub protein which interacts with numerous plant transcription factors from different families. It consists of three conserved domains and intervening unstructured regions, the C-terminal RST domain being responsible for the interactions...

journal_title：Biomolecular NMR assignments

authors： Tossavainen H,Hellman M,Vainonen JP,Kangasjärvi J,Permi P

更新日期：2017-10-01 00:00:00

abstract：:FK506 Binding Proteins (FKBPs) are a family of highly conserved and important proteins that possess a peptidyl cis-trans isomerase (PPIases) domain. Human FKBP12 is a prototype of this family and it is involved in many diseases due to its interaction with the immunosuppressive drugs FK506 and rapamycin. They inhibit c...

journal_title：Biomolecular NMR assignments

authors： Andrade GC,Silva LFC,Oliveira DMP,Pires JRM,Almeida FCL,Anobom CD

更新日期：2019-04-01 00:00:00

abstract：:Salmonella typhimurium OppA is the periplasmic oligopeptide-binding protein. Backbone resonances of OppA(D419N) on its own were assigned for approximately 90% of residues. Missing residues are localised around the ligand-binding site, suggesting conformational flexibility in the unliganded state. ...

journal_title：Biomolecular NMR assignments

authors： Kurashima-Ito K,Moromisato K,Nishimura K,Wälchli M,Tame JR,Ito Y

更新日期：2007-07-01 00:00:00

abstract：:Nuclear Factor κB (NF-κB) is a family of five related transcription factors that recognize a κB DNA element on the promoter and enhancer regions of target genes and modulate their expression. Here we report a complete set of 1H, 13C, 15N backbone and side chain resonance assignments for the p50 DNA binding and dimeriz...

journal_title：Biomolecular NMR assignments

authors： Singh A,Dyson HJ

更新日期：2020-09-16 00:00:00

abstract：:The regulation and localization of the neuronal voltage gated Ca(2+) channel CaV1.2 is important for synaptic plasticity associated with learning and memory. The cytoskeletal protein, α-actinin-1 is known to interact with CaV1.2 and stabilize its localization at the postsynaptic membrane. Here we report both backbone ...

journal_title：Biomolecular NMR assignments

authors： Turner M,Anderson DE,Rajan S,Hell JW,Ames JB

更新日期：2016-04-01 00:00:00

abstract：:Fibroblast growth factor receptor (FGFR) 4 has been associated with progression of melanoma, breast, head and neck and hepatocellular carcinoma and is therefore an interesting target for therapeutic intervention (Ho et al. in J Hepatol 50:118-127, 2009). The extracellular D2 domain of the FGFR4 receptor contains a hep...

journal_title：Biomolecular NMR assignments

authors： Elshorst B,Saxena K,Schieborr U,Schwalbe H

更新日期：2013-10-01 00:00:00

abstract：:GNA2132 (Genome-derived Neisseria Antigen 2132) is a surface-exposed lipoprotein discovered by reverse vaccinology and expressed by genetically diverse Neisseria meningitidis strains (Pizza et al. 2000). The protein induces bactericidal antibodies against most strains of Meningococccus and has been included in a multi...

journal_title：Biomolecular NMR assignments

authors： Esposito V,Musi V,Veggi D,Pastore A,Pizza M

更新日期：2010-04-01 00:00:00

abstract：:The protein dimethyladenosine transferase 1 (Dim1) is a highly conserved protein occurring in organisms ranging from bacteria such as E. coli where it is named KsgA to humans. Since Dim1 is involved in the biogenesis of the small ribosomal subunit it is an essential protein. During ribosome biogenesis Dim1 acts as an ...

journal_title：Biomolecular NMR assignments

authors： Kaiser M,Hacker C,Duchardt-Ferner E,Wöhnert J

更新日期：2019-10-01 00:00:00

abstract：:We report the nearly complete 1H, 13C and 15N resonance assignments of the oxidized form (Cys(67)-Cys(70)) of the N-terminal domain of PilB from Neisseria meningitidis. Secondary structure determination using CSI method and TALOS leads mainly to the prediction of 7 alpha-helical and 5 beta-sheet parts. ...

journal_title：Biomolecular NMR assignments

authors： Quinternet M,Beaufils C,Neiers F,Tsan P,Boschi-Muller S,Averlant-Petit MC,Branlant G,Cung MT

更新日期：2007-07-01 00:00:00

abstract：:KKT4 is a kinetoplastid-specific microtubule-binding kinetochore protein that lacks significant similarity to any known kinetochore or microtubule-binding proteins. Here we present the 1H, 13C and 15N resonance assignments for several fragments from the microtubule-binding domain of KKT4 (KKT4115-343) from Trypanosoma...

journal_title：Biomolecular NMR assignments

authors： Ludzia P,Akiyoshi B,Redfield C

更新日期：2020-10-01 00:00:00

abstract：:PTPN5 is a protein tyrosine phosphatase that plays an integral role in regulating excitatory postsynaptic activity. The sequence-specific backbone assignments of the murine PTPN5 catalytic domain have been determined based on triple-resonance experiments using uniformly [(2)H,(13)C,(15)N]-labeled protein. ...

journal_title：Biomolecular NMR assignments

authors： Francis DM,Page R,Peti W

更新日期：2014-04-01 00:00:00

abstract：:The replication of the hepatitis B virus is initiated by binding of the viral reverse transcriptase protein complex to the apical stem loop of the epsilon element to place it next to the primer loop, from which a four nucleotide DNA primer is subsequently synthesized. Here, we present the (1)H/(13)C/(15)N NMR assignme...

journal_title：Biomolecular NMR assignments

authors： van der Werf RM,Girard FC,Nelissen F,Tessari M,Wijmenga SS

更新日期：2008-12-01 00:00:00

abstract：:Human heterogeneous nuclear ribonucleoprotein H (hnRNP H) regulates alternative splicing of HIV-1 Tat pre-mRNA. The structure of the first N-terminal domain (residues 1-104) of hnRNP H was solved and its binding to an exonic splicing silencer (pESS2) studied. For this, all backbone and 85% of side-chain resonance freq...

journal_title：Biomolecular NMR assignments

authors： Cabal S,van Heijenoort C,Guittet E

更新日期：2007-12-01 00:00:00

abstract：:As part of our NMR structure determination of the Human S100A1, we report nearly complete NMR chemical shift assignments for the (1)H, (13)C and (15)N nuclei. ...

journal_title：Biomolecular NMR assignments

authors： Gupta AA,Mohan SK,Chin Y

更新日期：2012-10-01 00:00:00

abstract：:TraI, the F plasmid-encoded nickase, is a 1,756 amino acid protein essential for conjugative transfer of F plasmid DNA from one bacterium to another. While crystal structures of N- and C-terminal domains of F TraI have been determined, central domains of the protein are structurally unexplored. These middle domains (b...

journal_title：Biomolecular NMR assignments

authors： Wright NT,Majumdar A,Schildbach JF

更新日期：2011-04-01 00:00:00

abstract：:The Src tyrosine kinase is the paradigm of an oncogenic kinase, and of regulation by intramolecular inhibitory interactions, as well as an important anticancer target due to its roles in cell proliferation and metastasis. The assignment of backbone (1)H(N), (13)C(α), (13)CO, and (15)N, and sidechain (13)C(β) resonance...

journal_title：Biomolecular NMR assignments

authors： Campos-Olivas R,Marenchino M,Scapozza L,Gervasio FL

更新日期：2011-10-01 00:00:00

abstract：:Ebola viral infections have resulted in several deadly epidemics in recent years in West and Central Africa. Because only one of the seven proteins encoded by the viral genome possesses enzymatic activity, disruption of protein-protein interactions is a promising route for antiviral drug development. We carried out a ...

journal_title：Biomolecular NMR assignments

authors： Lee W,Tonelli M,Wu C,Aceti DJ,Amarasinghe GK,Markley JL

更新日期：2019-10-01 00:00:00

abstract：:Arsenate reductases (ArsC) are a group of enzymes that play essential roles in biological arsenic detoxification pathways by catalyzing the intracellular reduction of arsenate to arsenite, which is subsequently extruded from the cells by specific transport systems. The ArsC protein from cyanobacterium Synechocystis sp...

journal_title：Biomolecular NMR assignments

authors： Yu C,Xia B,Jin C

更新日期：2011-04-01 00:00:00