Abstract:
:Nuclear Factor κB (NF-κB) is a family of five related transcription factors that recognize a κB DNA element on the promoter and enhancer regions of target genes and modulate their expression. Here we report a complete set of 1H, 13C, 15N backbone and side chain resonance assignments for the p50 DNA binding and dimerization domains of the p50 homodimer form of the NF-κB transcription factor. The chemical shift data constitute a first step towards understanding the mechanism of interaction of the p50 homodimer with DNA.
journal_name
Biomol NMR Assignjournal_title
Biomolecular NMR assignmentsauthors
Singh A,Dyson HJdoi
10.1007/s12104-020-09978-zsubject
Has Abstractpub_date
2020-09-16 00:00:00eissn
1874-2718issn
1874-270Xpii
10.1007/s12104-020-09978-zpub_type
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journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
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