Abstract:
:Human heterogeneous nuclear ribonucleoprotein H (hnRNP H) regulates alternative splicing of HIV-1 Tat pre-mRNA. The structure of the first N-terminal domain (residues 1-104) of hnRNP H was solved and its binding to an exonic splicing silencer (pESS2) studied. For this, all backbone and 85% of side-chain resonance frequencies were assigned.
journal_name
Biomol NMR Assignjournal_title
Biomolecular NMR assignmentsauthors
Cabal S,van Heijenoort C,Guittet Edoi
10.1007/s12104-007-9061-9subject
Has Abstractpub_date
2007-12-01 00:00:00pages
221-3issue
2eissn
1874-2718issn
1874-270Xjournal_volume
1pub_type
杂志文章abstract::A peptide or a small protein released from an exocrine gland or in urine is utilized as a chemosignal that elicits social or reproductive behavior in mice. Recently, we identified the male-specific peptide, exocrine gland-secreting peptide 1 (ESP1), in mouse tear fluids that enhanced female sexual receptive behavior, ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-012-9441-7
更新日期:2014-04-01 00:00:00
abstract::RegB is involved in the control of the phage T4 life cycle. It inactivates the phage early mRNAs when their translation is no more required. We determined its structure and identified residues involved in substrate binding. For this, all backbone and 90% of side-chain resonance frequencies were assigned. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9021-4
更新日期:2007-07-01 00:00:00
abstract::Arsenate reductases (ArsC) are a group of enzymes that play essential roles in biological arsenic detoxification pathways by catalyzing the intracellular reduction of arsenate to arsenite, which is subsequently extruded from the cells by specific transport systems. The ArsC protein from cyanobacterium Synechocystis sp...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-010-9273-2
更新日期:2011-04-01 00:00:00
abstract::The S100 family belongs to the EF-hand calcium-binding proteins regulating a wide range of important cellular processes via protein-protein interactions. Most S100 proteins adopt a conformation of non-covalent homodimer for their functions. Calcium binding to the EF-hand motifs of S100 proteins is essential for trigge...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-012-9412-z
更新日期:2013-10-01 00:00:00
abstract::X-linked inhibitor of apoptosis protein (XIAP), a leading member of the family of inhibitor of apoptosis (IAP) proteins, is considered as the most potent and versatile inhibitor of caspases and apoptosis. It has been reported that XIAP is frequently overexpressed in cancer and its expression level is implicated in con...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-009-9197-x
更新日期:2010-04-01 00:00:00
abstract::The agglutinin-like-sequence (ALS) family of adhesion proteins are a key virulence factor for C. albicans. These proteins have been implicated in several functions, notably adhesion and invasion of different cell types, as well as binding to peptides and proteins in the cell surface and extracellular matrix. In order ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-010-9243-8
更新日期:2010-10-01 00:00:00
abstract::Phosphoenolpyruvate binding to the C-terminal domain (EIC) of enzyme I of the bacterial phosphotransferase system (PTS) initiates a phosphorylation cascade that results in sugar translocation across the cell membrane and controls a large number of essential pathways in bacterial metabolism. EIC undergoes an expanded t...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-017-9788-x
更新日期:2018-04-01 00:00:00
abstract::Sulfolobus solfataricus DNA polymerase IV (Dpo4), a prototype Y-family DNA polymerase, contains a unique little finger domain besides a catalytic core. Here, we report the chemical shift assignments for the backbone nitrogens, α and β carbons, and amide protons of the little finger domain of Dpo4. This work and our pu...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-011-9298-1
更新日期:2011-10-01 00:00:00
abstract::LicT belongs to an essential family of bacterial antitermination proteins which bind to nascent mRNAs in order to stimulate transcription of sugar-metabolizing operons. As most of other antitermination proteins involved in carbohydrate metabolism, LicT is composed of a N-terminal RNA-binding module (CAT) and two homol...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-019-09914-w
更新日期:2020-04-01 00:00:00
abstract::Plasmodium falciparum is responsible for causing cerebral malaria in humans. IMP1 is an immunogenic protein, present in the parasite, which has been shown to induce an immune response against apicomplexan parasites in a species-specific manner. Here, we report the complete NMR assignments of PfIMP1. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-015-9616-0
更新日期:2015-10-01 00:00:00
abstract::Ras homologue enriched in brain (Rheb) is a small GTPase that plays an important role in tuberous sclerosis. Here we present the backbone assignments of activated rRheb in complex with the non-hydrolisable GTP analogue GppNHp. These assignments now provide a basis for the analysis of rRheb's interaction with putative ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9030-3
更新日期:2007-07-01 00:00:00
abstract::The PilF protein from the thermophilic bacterium Thermus thermophilus is a traffic ATPase powering the assembly of the DNA translocation machinery as well as of type 4 pili. Thereby PilF mediates the natural transformability of T. thermophilus. PilF contains a C-terminal ATPase domain and three N-terminal domains with...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-019-09911-z
更新日期:2019-10-01 00:00:00
abstract::ITCH (aka Atrophin-1-interacting protein 4) is a prominent member of the NEDD4 HECT (Homologous to E6AP C-Terminus) E3 ubiquitin ligase family that regulates numerous cellular functions including inflammatory responses through T-cell activation, cell differentiation, and apoptosis. Known intracellular targets of ITCH-...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-018-9843-2
更新日期:2019-04-01 00:00:00
abstract::Q38FZ4 (UniProt accession number), is an 85-residue hypothetical protein from Trypanosoma brucei (T. brucei). Q38FZ4, which might be specific among the trypanosomatid genomes, shares low sequence similarity with mammal proteins and also has an essential function in the growth of T. brucei. Here we report the resonance...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-020-09956-5
更新日期:2020-10-01 00:00:00
abstract::We report the nearly complete 1H, 13C and 15N resonance assignments of the oxidized form (Cys(67)-Cys(70)) of the N-terminal domain of PilB from Neisseria meningitidis. Secondary structure determination using CSI method and TALOS leads mainly to the prediction of 7 alpha-helical and 5 beta-sheet parts. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9038-8
更新日期:2007-07-01 00:00:00
abstract::Repressor of primer (Rop, or ROM, RNA I modulator) is a 63 amino acid four-helix bundle protein that exists in solution as an anti-parallel homodimer. This protein has been extensively studied, including by X-ray crystallography, NMR, rational design, and combinatorial mutagenesis. Previous NMR experiments with wild-t...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-018-9837-0
更新日期:2018-10-01 00:00:00
abstract::The C-terminally truncated Y145Stop variant of prion protein (PrP23-144) has been linked to a heritable prionopathy in humans and is also capable of triggering a transmissible prion disease in mice. PrP23-144 can be converted from soluble monomeric form to amyloid under physiological conditions, providing an in vitro ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-020-09981-4
更新日期:2020-10-29 00:00:00
abstract::The gelation factor from Dictyostelium discoideum (ABP-120) is an actin binding protein consisting of six immunoglobulin (Ig) domains in the C-terminal rod domain. We have recently used the pair of domains 5 and 6 of ABP-120 as a model system for studying multi-domain nascent chain folding on the ribosome. Here we pre...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-008-9134-4
更新日期:2009-06-01 00:00:00
abstract::We report here the resonance assignment of EDK-∆-Bd37, conformational mutant potentially displaying the "open" conformation of Bd37, a 25 kDa surface protein from the Apicomplexa parasite Babesia divergens that could undergo drastic conformational changes during erythrocyte invasion. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-012-9418-6
更新日期:2013-10-01 00:00:00
abstract::Vibrio cholerae is the bacterial causative agent of the human disease cholera. Non-pathogenic bacterium can be converted to pathogenic following infection by a filamentous phage, CTXΦ, that carries the cholera toxin encoding genes. A crucial step during phage infection requires a direct interaction between the CTXΦ mi...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-016-9690-y
更新日期:2016-10-01 00:00:00
abstract::Ubiquitin Specific Protease 25 (USP25), a member of the deubiquitinase family, is involved in several disease-related signal pathways including myogenesis, immunity and protein degradation. It specially catalyzes the hydrolysis of the K48-linked and K63-linked polyubiquitin chains. USP25 contains one ubiquitin-associa...
journal_title:Biomolecular NMR assignments
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doi:10.1007/s12104-013-9495-1
更新日期:2014-10-01 00:00:00
abstract::Galectins recognize β-galectosides to promote a variety of cellular functions. Despite their sequence variations, all galectins share the same carbohydrate recognition domains (CRD) and their modes of ligand recognition at a structural level are essentially identical. Human galectin 8 plays an important role in numero...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-015-9623-1
更新日期:2015-10-01 00:00:00
abstract::The Src tyrosine kinase is the paradigm of an oncogenic kinase, and of regulation by intramolecular inhibitory interactions, as well as an important anticancer target due to its roles in cell proliferation and metastasis. The assignment of backbone (1)H(N), (13)C(α), (13)CO, and (15)N, and sidechain (13)C(β) resonance...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-011-9304-7
更新日期:2011-10-01 00:00:00
abstract::The mitochondrial antiviral signalling protein (MAVS) is a central signal transduction hub in the innate immune response against viral infections. Viral RNA present in the cytoplasm is detected by retinoic acid inducible gene I like receptors, which then activate MAVS via heterotypic interactions between their respect...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-014-9579-6
更新日期:2015-10-01 00:00:00
abstract::We report NMR assignments of the protein backbone of the C-terminal domain (163 a.a.) of human class 1 translation termination factor eRF1. It was found that several protein loop residues exist in two slowly interconverting conformational states. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9050-z
更新日期:2007-12-01 00:00:00
abstract::Latent TGFβ binding protein 1 (LTBP1) is a large extracellular protein that has been shown to bind covalently to the propeptide of TGFβ cytokines and form a large latent complex, which is then incapable of binding TGFβ receptors. LTBP1 has also been demonstrated to interact with a number of insoluble extracellular mat...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-013-9474-6
更新日期:2014-04-01 00:00:00
abstract::The pathogenic bacterium Staphylococcus aureus has evolved to actively evade many aspects of the human innate immune system by expressing a series of secreted inhibitory proteins. Among these, the extracellular adherence protein (Eap) has been shown to inhibit the classical and lectin pathways of the complement system...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-016-9688-5
更新日期:2016-10-01 00:00:00
abstract::Bacillus subtilis ATCC 6633 produces the lipid II targeting lantibiotic subtilin. For self-protection these gram-positive bacteria express a cluster of four self-immunity proteins named SpaIFEG. SpaI is a 16.8 kDa lipoprotein which is attached to the outside of the cytoplasmic membrane via a covalently linked diacylgl...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-011-9314-5
更新日期:2012-04-01 00:00:00
abstract::Light chain (AL) amyloidosis is a systemic disease characterized by the formation of immunoglobulin light-chain fibrils in critical organs of the body. The light-chain protein AL-09 presents one severe case of cardiac AL amyloidosis, which contains seven mutations in the variable domain (VL) relative to its germline c...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-016-9718-3
更新日期:2017-04-01 00:00:00
abstract::TraI, the F plasmid-encoded nickase, is a 1,756 amino acid protein essential for conjugative transfer of F plasmid DNA from one bacterium to another. While crystal structures of N- and C-terminal domains of F TraI have been determined, central domains of the protein are structurally unexplored. These middle domains (b...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-010-9269-y
更新日期:2011-04-01 00:00:00