Abstract:
:We report here the resonance assignment of EDK-∆-Bd37, conformational mutant potentially displaying the "open" conformation of Bd37, a 25 kDa surface protein from the Apicomplexa parasite Babesia divergens that could undergo drastic conformational changes during erythrocyte invasion.
journal_name
Biomol NMR Assignjournal_title
Biomolecular NMR assignmentsauthors
Barthe P,Murciano B,Schetters T,Gorenflot A,Delbecq S,Roumestand Cdoi
10.1007/s12104-012-9418-6subject
Has Abstractpub_date
2013-10-01 00:00:00pages
241-4issue
2eissn
1874-2718issn
1874-270Xjournal_volume
7pub_type
杂志文章abstract::Hydrophobins are fungal proteins characterised by their amphipathic properties and an idiosyncratic pattern of eight cysteine residues involved in four disulphide bridges. The soluble form of these proteins spontaneously self-assembles at hydrophobic/hydrophilic interfaces to form an amphipathic monolayer. The RodA hy...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-014-9555-1
更新日期:2015-04-01 00:00:00
abstract::TAR RNA binding protein (TRBP) is a double-stranded RNA binding protein involved in various biological processes like cell growth, development, death, etc. The protein exists as two isoforms TRBP2 and TRBP1. TRBP2 contains additional 21 amino acids at its N-terminus, which are proposed to be involved in its membrane l...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-018-9807-6
更新日期:2018-04-01 00:00:00
abstract::The mitochondrial antiviral signalling protein (MAVS) is a central signal transduction hub in the innate immune response against viral infections. Viral RNA present in the cytoplasm is detected by retinoic acid inducible gene I like receptors, which then activate MAVS via heterotypic interactions between their respect...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-014-9579-6
更新日期:2015-10-01 00:00:00
abstract::Latent TGFβ binding protein 1 (LTBP1) is a large extracellular protein that has been shown to bind covalently to the propeptide of TGFβ cytokines and form a large latent complex, which is then incapable of binding TGFβ receptors. LTBP1 has also been demonstrated to interact with a number of insoluble extracellular mat...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-013-9474-6
更新日期:2014-04-01 00:00:00
abstract::FK506 Binding Proteins (FKBPs) are a family of highly conserved and important proteins that possess a peptidyl cis-trans isomerase (PPIases) domain. Human FKBP12 is a prototype of this family and it is involved in many diseases due to its interaction with the immunosuppressive drugs FK506 and rapamycin. They inhibit c...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-019-09884-z
更新日期:2019-04-01 00:00:00
abstract::The replication of the hepatitis B virus is initiated by binding of the viral reverse transcriptase protein complex to the apical stem loop of the epsilon element to place it next to the primer loop, from which a four nucleotide DNA primer is subsequently synthesized. Here, we present the (1)H/(13)C/(15)N NMR assignme...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-008-9106-8
更新日期:2008-12-01 00:00:00
abstract::Snu13p is a highly conserved RNA binding protein from Saccharomyces cerevisiae required for both eukaryotic pre-mRNA splicing and pre-rRNA processing. The 1H, 13C, and 15N assignments were determined from multidimensional, multinuclear NMR experiments conducted at 25 degrees C. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9069-1
更新日期:2008-06-01 00:00:00
abstract::RegB is involved in the control of the phage T4 life cycle. It inactivates the phage early mRNAs when their translation is no more required. We determined its structure and identified residues involved in substrate binding. For this, all backbone and 90% of side-chain resonance frequencies were assigned. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9021-4
更新日期:2007-07-01 00:00:00
abstract::The cDNA of UVI31+ was cloned from C. reinhardtii and expressed in E. coli from where the protein was purified to homogeneity. The purified protein exhibited beta-lactamase activity (Manuscript in preparation). However, UVI31+ has no homology with the known β-lactamases. In order to understand the structural basis of ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-010-9239-4
更新日期:2010-10-01 00:00:00
abstract::Heterogeneous nuclear ribonucleoproteins (hnRNPs) can be divided into subgroups based on their RNA-binding characteristics. One subgroup in mammalian cells are the Poly(C)-binding proteins (PCBPs) comprised of hnRNP K/J and hnRNP E1-4 [the latter also known as PCBP 1-4 or α-complex proteins (α-CP) 1-4]. Each subgroup ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-015-9624-0
更新日期:2015-10-01 00:00:00
abstract::Yeast Fpr4p belongs to the FK506-binding protein (FKBP) class of peptidyl proline isomerases (PPIases), and has been implicated in regulating the cis-trans conversion of proline residues within histone tails. Here we report the (1)H, (13)C and (15)N chemical shift assignments for the bacterially expressed C-terminal P...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-011-9338-x
更新日期:2012-10-01 00:00:00
abstract::Chromatin remodelling proteins are an essential family of eukaryotic proteins. They harness the energy from ATP hydrolysis and apply it to alter chromatin structure in order to regulate all aspects of genome biology. Chromodomain helicase DNA-binding protein 1 (CHD1) is one such remodelling protein that has specialise...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-015-9631-1
更新日期:2016-04-01 00:00:00
abstract::Galectins recognize β-galectosides to promote a variety of cellular functions. Despite their sequence variations, all galectins share the same carbohydrate recognition domains (CRD) and their modes of ligand recognition at a structural level are essentially identical. Human galectin 8 plays an important role in numero...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-015-9623-1
更新日期:2015-10-01 00:00:00
abstract::NOXO1 (Nox Organizer 1) is a homolog of the NAPDH oxidase protein p47(phox). NADPH oxidases transfer electrons from NADPH to molecular oxygen, generating the superoxide anion. NOXO1 contains an N-terminal PX (phox homology) domain and is one of several PX domain-containing proteins found in the cytosolic subunits of t...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-010-9286-x
更新日期:2011-10-01 00:00:00
abstract::Cohesin and dockerin domains are critical assembling components of cellulosome, a large extracellular multienzyme complex which is used by anaerobic cellulolytic bacteria to efficiently degrade lignocellulose. According to sequence homology, cohesins can be divided into three major groups, whereas cohesins from Clostr...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-012-9381-2
更新日期:2013-04-01 00:00:00
abstract::Hsp70 chaperone proteins play crucial roles in the cell. Extensive structural and functional studies have been performed for bacterial and mammalian Hsp70s. Ssa1 from Saccharomyces cerevisiae is a member of the Hsp70 family. In vivo and biochemical studies on Ssa1 have revealed that it regulates prion propagation and ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-015-9603-5
更新日期:2015-10-01 00:00:00
abstract::We report the nearly complete 1H, 13C and 15N resonance assignments of the oxidized form (Cys(67)-Cys(70)) of the N-terminal domain of PilB from Neisseria meningitidis. Secondary structure determination using CSI method and TALOS leads mainly to the prediction of 7 alpha-helical and 5 beta-sheet parts. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9038-8
更新日期:2007-07-01 00:00:00
abstract::Ubiquitin Specific Protease 25 (USP25), a member of the deubiquitinase family, is involved in several disease-related signal pathways including myogenesis, immunity and protein degradation. It specially catalyzes the hydrolysis of the K48-linked and K63-linked polyubiquitin chains. USP25 contains one ubiquitin-associa...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-013-9495-1
更新日期:2014-10-01 00:00:00
abstract::The protein dimethyladenosine transferase 1 (Dim1) is a highly conserved protein occurring in organisms ranging from bacteria such as E. coli where it is named KsgA to humans. Since Dim1 is involved in the biogenesis of the small ribosomal subunit it is an essential protein. During ribosome biogenesis Dim1 acts as an ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00
abstract::During its life cycle, the malaria parasite Plasmodium falciparum is found intracellular to human erythrocytes, where its survival and ability to multiply critically depends on the control of the environment redox state. Thioredoxin is a small protein containing 104 amino acids that is part of the parasite specific re...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-009-9163-7
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journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9050-z
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abstract::The A. thaliana RCD1 (radical-induced cell death1) protein is a cellular signaling hub protein which interacts with numerous plant transcription factors from different families. It consists of three conserved domains and intervening unstructured regions, the C-terminal RST domain being responsible for the interactions...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-017-9749-4
更新日期:2017-10-01 00:00:00
abstract::As part of our NMR structure determination of the Human S100A1, we report nearly complete NMR chemical shift assignments for the (1)H, (13)C and (15)N nuclei. ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-012-9360-7
更新日期:2012-10-01 00:00:00
abstract::GNA2132 (Genome-derived Neisseria Antigen 2132) is a surface-exposed lipoprotein discovered by reverse vaccinology and expressed by genetically diverse Neisseria meningitidis strains (Pizza et al. 2000). The protein induces bactericidal antibodies against most strains of Meningococccus and has been included in a multi...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-010-9220-2
更新日期:2010-04-01 00:00:00
abstract::YbeA is a 3-methylpseudoridine methyltransferase from Escherichia coli that forms a stable homodimer in solution. It is one of the deeply trefoil 31 knotted proteins, of which the knot encompasses the C-terminal helix that threads through a long loop. Recent studies on the knotted protein folding pathways using YbeA h...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-013-9501-7
更新日期:2014-10-01 00:00:00
abstract::The pathogenic bacterium Staphylococcus aureus has evolved to actively evade many aspects of the human innate immune system by expressing a series of secreted inhibitory proteins. Among these, the extracellular adherence protein (Eap) has been shown to inhibit the classical and lectin pathways of the complement system...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00
abstract::A peptide or a small protein released from an exocrine gland or in urine is utilized as a chemosignal that elicits social or reproductive behavior in mice. Recently, we identified the male-specific peptide, exocrine gland-secreting peptide 1 (ESP1), in mouse tear fluids that enhanced female sexual receptive behavior, ...
journal_title:Biomolecular NMR assignments
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journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-009-9197-x
更新日期:2010-04-01 00:00:00
abstract::Ras homologue enriched in brain (Rheb) is a small GTPase that plays an important role in tuberous sclerosis. Here we present the backbone assignments of activated rRheb in complex with the non-hydrolisable GTP analogue GppNHp. These assignments now provide a basis for the analysis of rRheb's interaction with putative ...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
doi:10.1007/s12104-007-9030-3
更新日期:2007-07-01 00:00:00
abstract::E. coli nitroreductase NfsB (also called NfnB) has been studied extensively, largely due to its potential for cancer gene therapy. A homodimeric flavoprotein of 216 residues, it catalyses the reduction of nitroaromatics to cytotoxic hydroxylamines by NADH and NADPH and also the reduction of quinones to hydroxyquinones...
journal_title:Biomolecular NMR assignments
pub_type: 杂志文章
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更新日期:2021-01-09 00:00:00