Backbone 1H, 15N, and 13C resonance assignments for the NOXO1β PX domain.

abstract：:Phosphoenolpyruvate binding to the C-terminal domain (EIC) of enzyme I of the bacterial phosphotransferase system (PTS) initiates a phosphorylation cascade that results in sugar translocation across the cell membrane and controls a large number of essential pathways in bacterial metabolism. EIC undergoes an expanded t...

journal_title：Biomolecular NMR assignments

authors： Dotas RR,Venditti V

更新日期：2018-04-01 00:00:00

abstract：:Myeloid differentiating factor 88 (MyD88) is one of a critical adaptor molecule in the Toll-like receptor (TLR) signaling pathway. The TIR domain of MyD88 serves as a protein-protein interaction module and interacts with other TIR-containing proteins such as Mal (MyD88 adaptor-like) and Toll-like receptor 4 to form si...

journal_title：Biomolecular NMR assignments

authors： Ohnishi H,Tochio H,Kato Z,Kimura T,Hiroaki H,Kondo N,Shirakawa M

更新日期：2010-10-01 00:00:00

abstract：:During its life cycle, the malaria parasite Plasmodium falciparum is found intracellular to human erythrocytes, where its survival and ability to multiply critically depends on the control of the environment redox state. Thioredoxin is a small protein containing 104 amino acids that is part of the parasite specific re...

journal_title：Biomolecular NMR assignments

authors： Munte CE,Becker K,Schirmer RH,Kalbitzer HR

更新日期：2009-12-01 00:00:00

abstract：:Translationally-controlled tumor protein (TCTP) is a eukaryote-conserved protein with crucial roles in cellular growth. It has also been proposed that plant TCTP has functions specific to plant, while no structure of TCTP from photosynthetic organism has been reported. Nannochloropsis is a photosynthetic microalga wit...

journal_title：Biomolecular NMR assignments

authors： Yao X,Xiao Y,Cui Q,Feng Y

更新日期：2015-10-01 00:00:00

abstract：:The bacterium Geobacter metallireducens is capable of transferring electrons to the cell exterior, a process designated extracellular electron transfer. This mechanism allows the microorganism to reduce extracellular acceptors such as Fe(III) (hydr)oxides and water toxic and/or radioactive contaminants including Cr(VI...

journal_title：Biomolecular NMR assignments

authors： Portela PC,Dantas JM,Salgueiro CA

更新日期：2020-04-01 00:00:00

abstract：:PRK1 is a member of the protein kinase C-related kinase (PRK) family of serine/threonine kinases and a downstream effector of Rho GTPases. PRK1 has three N-terminal Homology Region 1 (HR1) domains (HR1a, HR1b and HR1c), which form antiparallel coiled coils that interact with Rho family GTPases. PRK1 also has a C2-like...

journal_title：Biomolecular NMR assignments

authors： Sophocleous G,Wood G,Owen D,Mott HR

更新日期：2020-10-01 00:00:00

abstract：:The peptidoglycan is a major component of the bacterial cell wall and is essential to maintain cellular integrity and cell shape. Penicillin-Binding Proteins (PBPs) catalyze the final biosynthetic steps of peptidoglycan synthesis from lipid II precursor and are the main targets of β-lactam antibiotics. The molecular d...

journal_title：Biomolecular NMR assignments

authors： Jean NL,Bougault C,Derouaux A,Callens G,Vollmer W,Simorre JP

更新日期：2015-04-01 00:00:00

abstract：:The cDNA of UVI31+ was cloned from C. reinhardtii and expressed in E. coli from where the protein was purified to homogeneity. The purified protein exhibited beta-lactamase activity (Manuscript in preparation). However, UVI31+ has no homology with the known β-lactamases. In order to understand the structural basis of ...

journal_title：Biomolecular NMR assignments

authors： Rout AK,Minda R,Peri D,Ramakrishnan V,Bhattacharjee SK,Rao BJ,Chary KV

更新日期：2010-10-01 00:00:00

abstract：:Ubiquitin Specific Protease 25 (USP25), a member of the deubiquitinase family, is involved in several disease-related signal pathways including myogenesis, immunity and protein degradation. It specially catalyzes the hydrolysis of the K48-linked and K63-linked polyubiquitin chains. USP25 contains one ubiquitin-associa...

journal_title：Biomolecular NMR assignments

authors： Shi L,Wen Y,Zhang N

更新日期：2014-10-01 00:00:00

abstract：:We report the nearly complete 1H, 13C and 15N resonance assignments of the oxidized form (Cys(67)-Cys(70)) of the N-terminal domain of PilB from Neisseria meningitidis. Secondary structure determination using CSI method and TALOS leads mainly to the prediction of 7 alpha-helical and 5 beta-sheet parts. ...

journal_title：Biomolecular NMR assignments

authors： Quinternet M,Beaufils C,Neiers F,Tsan P,Boschi-Muller S,Averlant-Petit MC,Branlant G,Cung MT

更新日期：2007-07-01 00:00:00

abstract：:RpsA, also known as ribosomal protein S1, is an essential protein required for translation initiation of mRNAs when their Shine-Dalgarno sequence is degenerated (Sorensen et al. 1998). In addition, RpsA of Mycobacterium tuberculosis (M. tb) is involved in trans-translation, which is an effective system mediated by tmR...

journal_title：Biomolecular NMR assignments

authors： Fu J,Huang B,Lin D,Liao X

更新日期：2017-10-01 00:00:00

abstract：:Salmonella typhimurium OppA is the periplasmic oligopeptide-binding protein. Backbone resonances of OppA(D419N) on its own were assigned for approximately 90% of residues. Missing residues are localised around the ligand-binding site, suggesting conformational flexibility in the unliganded state. ...

journal_title：Biomolecular NMR assignments

authors： Kurashima-Ito K,Moromisato K,Nishimura K,Wälchli M,Tame JR,Ito Y

更新日期：2007-07-01 00:00:00

abstract：:The mitochondrial antiviral signalling protein (MAVS) is a central signal transduction hub in the innate immune response against viral infections. Viral RNA present in the cytoplasm is detected by retinoic acid inducible gene I like receptors, which then activate MAVS via heterotypic interactions between their respect...

journal_title：Biomolecular NMR assignments

authors： He L,Lührs T,Ritter C

更新日期：2015-10-01 00:00:00

abstract：:KKT4 is a kinetoplastid-specific microtubule-binding kinetochore protein that lacks significant similarity to any known kinetochore or microtubule-binding proteins. Here we present the 1H, 13C and 15N resonance assignments for several fragments from the microtubule-binding domain of KKT4 (KKT4115-343) from Trypanosoma...

journal_title：Biomolecular NMR assignments

authors： Ludzia P,Akiyoshi B,Redfield C

更新日期：2020-10-01 00:00:00

abstract：:The Breast Cancer susceptibility protein 2 (BRCA2) is involved in mechanisms that maintain genome stability, including DNA repair, replication and cell division. These functions are ensured by the folded C-terminal DNA binding domain of BRCA2 but also by its large regions predicted to be disordered. Several studies ha...

journal_title：Biomolecular NMR assignments

authors： Julien M,Miron S,Carreira A,Theillet FX,Zinn-Justin S

更新日期：2020-04-01 00:00:00

abstract：:Yeast Fpr4p belongs to the FK506-binding protein (FKBP) class of peptidyl proline isomerases (PPIases), and has been implicated in regulating the cis-trans conversion of proline residues within histone tails. Here we report the (1)H, (13)C and (15)N chemical shift assignments for the bacterially expressed C-terminal P...

journal_title：Biomolecular NMR assignments

authors： Monneau YR,Nelson CJ,Mackereth CD

更新日期：2012-10-01 00:00:00

abstract：:Ebola viral infections have resulted in several deadly epidemics in recent years in West and Central Africa. Because only one of the seven proteins encoded by the viral genome possesses enzymatic activity, disruption of protein-protein interactions is a promising route for antiviral drug development. We carried out a ...

journal_title：Biomolecular NMR assignments

authors： Lee W,Tonelli M,Wu C,Aceti DJ,Amarasinghe GK,Markley JL

更新日期：2019-10-01 00:00:00

abstract：:The S100 family belongs to the EF-hand calcium-binding proteins regulating a wide range of important cellular processes via protein-protein interactions. Most S100 proteins adopt a conformation of non-covalent homodimer for their functions. Calcium binding to the EF-hand motifs of S100 proteins is essential for trigge...

journal_title：Biomolecular NMR assignments

authors： Hung KW,Chang YM,Yu C

更新日期：2013-10-01 00:00:00

abstract：:The C-terminally truncated Y145Stop variant of prion protein (PrP23-144) has been linked to a heritable prionopathy in humans and is also capable of triggering a transmissible prion disease in mice. PrP23-144 can be converted from soluble monomeric form to amyloid under physiological conditions, providing an in vitro ...

journal_title：Biomolecular NMR assignments

authors： Dao HH,Hlaing MZ,Ma Y,Surewicz K,Surewicz WK,Jaroniec CP

更新日期：2020-10-29 00:00:00

abstract：:Parkinson's disease (PD) is a chronic, progressive neurodegenerative disease, where dopaminergic cells die most prominently in the area of substantia nigra. Neurotrophic factors (NTFs) are secreted proteins, which upon binding to their target receptors trigger survival pathways to prevent neuronal loss. Recently disco...

journal_title：Biomolecular NMR assignments

authors： Hellman M,Peränen J,Saarma M,Permi P

更新日期：2010-10-01 00:00:00

abstract：:YbeA is a 3-methylpseudoridine methyltransferase from Escherichia coli that forms a stable homodimer in solution. It is one of the deeply trefoil 31 knotted proteins, of which the knot encompasses the C-terminal helix that threads through a long loop. Recent studies on the knotted protein folding pathways using YbeA h...

journal_title：Biomolecular NMR assignments

authors： Hsieh SJ,Mallam AL,Jackson SE,Hsu ST

更新日期：2014-10-01 00:00:00

abstract：:The pathogenic bacterium Staphylococcus aureus has evolved to actively evade many aspects of the human innate immune system by expressing a series of secreted inhibitory proteins. Among these, the extracellular adherence protein (Eap) has been shown to inhibit the classical and lectin pathways of the complement system...

journal_title：Biomolecular NMR assignments

authors： Woehl JL,Takahashi D,Herrera AI,Geisbrecht BV,Prakash O

更新日期：2016-10-01 00:00:00

abstract：:The catalytic subunit of protein kinase A is involved with a number of signal transduction pathways and has been used as a benchmark to study the structural biology and biochemistry for the entire kinase family of enzymes. Here, we report the backbone assignment of the intact 41 kDa catalytic subunit bound to AMP-PNP....

journal_title：Biomolecular NMR assignments

authors： Masterson LR,Shi L,Tonelli M,Mascioni A,Mueller MM,Veglia G

更新日期：2009-06-01 00:00:00

abstract：:Snu13p is a highly conserved RNA binding protein from Saccharomyces cerevisiae required for both eukaryotic pre-mRNA splicing and pre-rRNA processing. The 1H, 13C, and 15N assignments were determined from multidimensional, multinuclear NMR experiments conducted at 25 degrees C. ...

journal_title：Biomolecular NMR assignments

authors： Workman H,Skalicky JJ,Flynn PF

更新日期：2008-06-01 00:00:00

abstract：:A peptide or a small protein released from an exocrine gland or in urine is utilized as a chemosignal that elicits social or reproductive behavior in mice. Recently, we identified the male-specific peptide, exocrine gland-secreting peptide 1 (ESP1), in mouse tear fluids that enhanced female sexual receptive behavior, ...

journal_title：Biomolecular NMR assignments

authors： Taniguchi M,Yoshinaga S,Haga-Yamanaka S,Touhara K,Terasawa H

更新日期：2014-04-01 00:00:00

abstract：:Galectins recognize β-galectosides to promote a variety of cellular functions. Despite their sequence variations, all galectins share the same carbohydrate recognition domains (CRD) and their modes of ligand recognition at a structural level are essentially identical. Human galectin 8 plays an important role in numero...

journal_title：Biomolecular NMR assignments

authors： Liu CH,Chien CT,Lin CH,Hsu ST

更新日期：2015-10-01 00:00:00

abstract：:Imatinib (Glivec or Gleevec) potently inhibits the tyrosine kinase activity of BCR-ABL, a constitutively activated kinase, which causes chronic myelogenous leukemia (CML). Here we report the first almost complete backbone assignment of c-ABL kinase domain in complex with imatinib. ...

journal_title：Biomolecular NMR assignments

authors： Vajpai N,Strauss A,Fendrich G,Cowan-Jacob SW,Manley PW,Jahnke W,Grzesiek S

更新日期：2008-06-01 00:00:00

abstract：:RegB is involved in the control of the phage T4 life cycle. It inactivates the phage early mRNAs when their translation is no more required. We determined its structure and identified residues involved in substrate binding. For this, all backbone and 90% of side-chain resonance frequencies were assigned. ...

journal_title：Biomolecular NMR assignments

authors： Odaert B,Saïda F,Bontems F

更新日期：2007-07-01 00:00:00

abstract：:The gelation factor from Dictyostelium discoideum (ABP-120) is an actin binding protein consisting of six immunoglobulin (Ig) domains in the C-terminal rod domain. We have recently used the pair of domains 5 and 6 of ABP-120 as a model system for studying multi-domain nascent chain folding on the ribosome. Here we pre...

journal_title：Biomolecular NMR assignments

authors： Hsu ST,Cabrita LD,Christodoulou J,Dobson CM

更新日期：2009-06-01 00:00:00

abstract：:The regulation and localization of the neuronal voltage gated Ca(2+) channel CaV1.2 is important for synaptic plasticity associated with learning and memory. The cytoskeletal protein, α-actinin-1 is known to interact with CaV1.2 and stabilize its localization at the postsynaptic membrane. Here we report both backbone ...

journal_title：Biomolecular NMR assignments

authors： Turner M,Anderson DE,Rajan S,Hell JW,Ames JB

更新日期：2016-04-01 00:00:00