Abstract:
:Phage ΦM12 is an important transducing phage of the nitrogen-fixing rhizobial bacterium Sinorhizobium meliloti. Here we report the genome, phylogenetic analysis, and proteome of ΦM12, the first report of the genome and proteome of a rhizobium-infecting T4-superfamily phage. The structural genes of ΦM12 are most similar to T4-superfamily phages of cyanobacteria. ΦM12 is the first reported T4-superfamily phage to lack genes encoding class I ribonucleotide reductase (RNR) and exonuclease dexA, and to possess a class II coenzyme B12-dependent RNR. ΦM12's novel collection of genes establishes it as the founder of a new group of T4-superfamily phages, fusing features of cyanophages and phages of enteric bacteria.
journal_name
Virologyjournal_title
Virologyauthors
Brewer TE,Stroupe ME,Jones KMdoi
10.1016/j.virol.2013.11.027subject
Has Abstractpub_date
2014-02-01 00:00:00pages
84-97eissn
0042-6822issn
1096-0341pii
S0042-6822(13)00649-1journal_volume
450-451pub_type
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