Activation of anterior pituitary folliculo-stellate cells in the formation of estrogen-induced prolactin-secreting tumors.

abstract：:Pathologies involving the pituitary stalk (PS) are generally revealed by the presence of diabetes insipidus. The availability of MRI provides a major diagnostic contribution by enabling the visualization of the site of the culprit lesion, especially when it is small. However, when only an enlarged PS is found, the eti...

journal_title：Neuroendocrinology

authors： Hána V,Salenave S,Chanson P

更新日期：2020-01-01 00:00:00

abstract：:Parturition is initiated in sheep by an increase in the activity of the fetal hypothalamus-pituitary-adrenal (HPA) axis. Prostaglandins, known to augment the activity of this endocrine axis, have long been proposed as involved in the initiation of paturition. We have previously demonstrated that endogenously produced ...

journal_title：Neuroendocrinology

authors： Deauseault D,Giroux D,Wood CE

更新日期：2000-05-01 00:00:00

abstract：:The storage form of prolactin (PRL) was converted into the releasable form in the lactating rat pituitary gland within 10 min of suckling by 6 pups following 4-5 h of nonsuckling on postpartum day 13-14. The characteristics of the PRL discharge from the releasable pool into the circulation was then studied using a sti...

journal_title：Neuroendocrinology

authors： Grosvenor CE

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:In 2014, the World Health Organization (WHO) released a classification system introducing neuroendocrine neoplasms (NENs) of the female reproductive tract, excluding the ovaries. This study aimed to evaluate whether retrospective adaption of the gastroenteropancreatic (GEP)-NEN classification is feasible for...

journal_title：Neuroendocrinology

authors： Kai K,Nasu K,Nishida H,Daa T,Shikama A,Shiozaki T,Kurakazu M,Yano M,Imamura Y,Tokunaga H,Tasaki K,Iida Y,Yamada Y,Morisawa H,Nakagawa S,Fujimoto E,Tsuruta T,Matsumoto H,Arakawa A,Nonaka M,Takano H,Ushiwaka T,M

更新日期：2020-02-25 00:00:00

abstract：:Serum prolactin was measured in lightly etherized rats between 4 and 5 a.m. and between 11 a.m. and 12 noon at various times after operation in intact rats and rats that had been operated on. Serum prolactin was elevated in the late nocturnal samples from intact rats and this elevation was prevented by pinealectomy. W...

journal_title：Neuroendocrinology

authors： Ronnekleiv OK,McCann SM

更新日期：1975-01-01 00:00:00

abstract：:A role for glutamate in signalling mechanisms in the mammalian pineal gland is suggested by the high concentration of the transmitter in pinealocytes and the expression of glutamate receptor subunits in the rat gland. A single type of glutamate binding site has been characterized in the rat and bovine pineal gland, pr...

journal_title：Neuroendocrinology

authors： Mick G

更新日期：1995-03-01 00:00:00

abstract：:Normal 4-day cyclic rats were sacrificed at 10 a.m. and 3 p.m. on proestrus or estrus and at 10 a.m. on metestrus. Noradrenaline (NA), dopamine (DA) and tryptophan (T) concentrations varied only slightly. Serotonin (5-HT) concentrations showed characteristic changing patterns in many hypothalamic, limbic and midbrain ...

journal_title：Neuroendocrinology

authors： Kueng W,Wirz-Justice A,Menzi R,Chappuis-Arndt E

更新日期：1976-01-01 00:00:00

abstract：:The effect of intraventricular and intravenous (i.v.) hypertonic saline on plasma and perfusate arginine vasopressin (AVP) and oxytocin (OT) levels was determined. A push-pull technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious unrestrained rat. Intraventricular perfusion of hyper...

journal_title：Neuroendocrinology

authors： Morris M,Barnard RR Jr,Sain LE

更新日期：1984-11-01 00:00:00

abstract：:Studies were conducted to determine if the hypothermic effects of barbiturates were responsible for their ability to suppress luteinizing hormone (LH) secretion in rats following ovariectomy or treatment with gonadal steroids. In both ovariectomized rats and rats treated with estradiol and progesterone, pentobarbital ...

journal_title：Neuroendocrinology

authors： Simpkins JW,Katovich MJ

更新日期：1987-09-01 00:00:00

abstract：:When fetal preoptic area (POA) brain grafts that contain gonadotropin-releasing hormone cells are transplanted into the third ventricle of adult female hypogonadal mice, the animals respond with sexual maturation, persistent estrus, and the ability to ovulate reflexively after mating. However, the absence of normal sp...

journal_title：Neuroendocrinology

authors： Gibson MJ,Kokoris GJ,Silverman AJ

更新日期：1988-08-01 00:00:00

abstract：:We have used excitatory amino acids as tools to elucidate changes in hypothalamic function associated with lactation, focusing on the regulation of luteinizing hormone (LH) and prolactin secretion. In these studies, we have compared the responsiveness to NMA (N-methyl-D,L-aspartate), an agonist for the N-methyl-D-aspa...

journal_title：Neuroendocrinology

authors： Abbud R,Smith MS

更新日期：1993-10-01 00:00:00

abstract：:Arginine-vasopressin (AVP) is regarded as a potent stimulator of pituitary adrenocorticotropin (ACTH) secretion and participates therefore in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis function in concert with the physiological activator of the axis, hypothalamic corticotropin-releasing hormone (C...

journal_title：Neuroendocrinology

authors： Bernardini R,Chiarenza A,Kamilaris TC,Renaud N,Lempereur L,Demitrack M,Gold PW,Chrousos GP

更新日期：1994-11-01 00:00:00

abstract：:The expression of the mouse metallothionein-I (mMT) promoter/human growth hormone (hGH) fusion gene in transgenic mice leads to female sterility and major alterations in the function of the hypothalamic-adenohypophyseal system. These alterations include increases in median-eminence norepinephrine turnover and plasma L...

journal_title：Neuroendocrinology

authors： Steger RW,Bartke A,Parkening TA,Collins T,Buonomo FC,Tang KC,Wagner TE,Yun JS

更新日期：1991-04-01 00:00:00

abstract：:The effect of steroids on the two gonadotropin-releasing hormone (GnRH) forms present in the eel (mammalian GnRH, mGnRH and chicken GnRH-II, cGnRH-II), as well as on gonadotropin (GTH), was studied using specific radioimmunoassays. Female silver eels received chronic treatments with various steroids (estradiol, testos...

journal_title：Neuroendocrinology

authors： Montero M,Le Belle N,King JA,Millar RP,Dufour S

更新日期：1995-05-01 00:00:00

abstract：:The differential role of porcine follicular fluid (pFF) in regulating follicle-stimulating hormone (FSH) and luteinizing hormone (LH) release in vivo in situations of different gonadotropin releasing hormone (GnRH) backgrounds was studied. In experiment 1, 2-week ovariectomized rats injected intravenously with 4, 16 o...

journal_title：Neuroendocrinology

authors： Charlesworth MC,Grady RR,Shin L,Vale WW,Rivier C,Rivier J,Schwartz NB

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND/AIMS:A mammalian circannual pacemaker responsible for regulating the seasonal pattern of prolactin has been recently described in sheep. This pacemaker resides within the pars tuberalis, an area of the pituitary gland that densely expresses melatonin receptors. However, the chemical identity of the cell type...

journal_title：Neuroendocrinology

authors： Hodson DJ,Townsend J,Tortonese DJ

更新日期：2013-01-01 00:00:00

abstract：:Previous reports have shown that dopamine (DA) in the zona incerta (ZI) has a stimulatory effect on gonadotrophin release. We have now investigated the possibility that steroids exert their feedback effects on the release of luteinizing hormone (LH) via catecholamine systems in the ZI. Since the same steroid regimes a...

journal_title：Neuroendocrinology

authors： Wilson CA,James MD,Grierson JP,Hole DR

更新日期：1991-02-01 00:00:00

abstract：:Hypothalamic norepinephrine (NE) and dopamine content was studied in dogs with spontaneous and iatrogenic hypercortisolism and in untreated normal dogs. The concentration of NE in the hypothalamus was subnormal in 4 of 8 dogs with pituitary-dependent hyperadrenocorticism (PDH), whereas long-term administration of cort...

journal_title：Neuroendocrinology

authors： Meijer JC,Croughs RJ,Rijnberk A,Versteeg DH,van Ree JM

更新日期：1981-04-01 00:00:00

abstract：:Tissue-specific stem cells are uncovered in a growing number of organs by their molecular expression profile and their potential for self-renewal, multipotent differentiation and tissue regeneration. Whether the pituitary gland also contains a pool of versatile 'master' cells that drive homeostatic, plastic and regene...

journal_title：Neuroendocrinology

authors： Vankelecom H

更新日期：2007-01-01 00:00:00

abstract：:To gain further insight into the regulation of hypothalamic TRH by thyroid hormones, we measured TRH concentration in specific hypothalamic nuclei and preproTRH mRNA levels in the anterior hypothalamus. Adult male rats were decapitated 1, 7, 14 days after thyroidectomy. Micropunches by the method of Palkovitz from sev...

journal_title：Neuroendocrinology

authors： Yamada M,Satoh T,Monden T,Murakami M,Iriuchijima T,Wilber JF,Mori M

更新日期：1992-03-01 00:00:00

abstract：:Thymic neuroendocrine neoplasms are rare tumours, but their management can often be highly problematic. While previously assumed to be essentially variants of bronchopulmonary (lung) carcinoids, they are generally more aggressive and more difficult to treat. Some 25% are associated with multiple endocrine neoplasia-1,...

journal_title：Neuroendocrinology

authors： Jia R,Sulentic P,Xu JM,Grossman AB

更新日期：2017-01-01 00:00:00

abstract：:We have investigated the effects of exposure to short-term constant light (LL) on the spontaneous, proestrous luteinizing hormone (LH) surge in the female rat. Exposure to LL during the 3 days preceding proestrus delayed and reduced the magnitude of the LH surge which was measured in blood samples taken from conscious...

journal_title：Neuroendocrinology

authors： Watts AG,Fink G

更新日期：1981-09-01 00:00:00

abstract：:Progesterone is readily reduced in humans to its A-ring metabolites, allopregnanolone (3 alpha-hydroxy-5 alpha-pregnan-20-one) and pregnanolone (3 alpha-hydroxy-5 beta-pregnan-20-one). The latter have been reported to have anxiolytic, hypnotic and anesthetic actions when administered to laboratory animals and (or) hum...

journal_title：Neuroendocrinology

authors： Freeman EW,Purdy RH,Coutifaris C,Rickels K,Paul SM

更新日期：1993-10-01 00:00:00

abstract：:Neurons synthesizing growth hormone releasing factor were detected by immunocytochemistry with specific antiserum against synthetic rat hypothalamic growth hormone releasing factor. Growth hormone releasing factor immunoreactive neurons which also showed tyrosine hydroxylase immunoreactivity were located in the ventro...

journal_title：Neuroendocrinology

authors： Okamura H,Murakami S,Chihara K,Nagatsu I,Ibata Y

更新日期：1985-08-01 00:00:00

abstract：:In human African trypanosomiasis (sleeping sickness), sleep and wake episodes are sporadically distributed throughout the day and the night. Plasma melatonin, sleep-wakefulness and rectal temperature rhythms were studied in 9 Congolese patients suffering from sleeping sickness compared to 6 healthy controls submitted ...

journal_title：Neuroendocrinology

authors： Claustrat B,Buguet A,Geoffriau M,Bogui P,Mouanga G,Stanghellini A,Dumas M

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:We previously presented data of this multicentric, phase II study showing that everolimus plus octreotide long-acting repeatable (LAR) for advanced neuroendocrine neoplasms (NENs), in the first line setting, is an active and safe treatment. We now present updated data at 5 years. METHODS:Patients with advan...

journal_title：Neuroendocrinology

authors： Bajetta E,Catena L,Pusceddu S,Spada F,Iannacone C,Sarno I,Di Menna G,Dottorini L,Marte AM

更新日期：2018-01-01 00:00:00

abstract：:Serotonin, a biologically active amine, is related to carcinoid syndrome in functioning neuroendocrine tumors (NETs). Telotristat ethyl is a novel inhibitor of the tryptophan hydroxylase (TPH), a key enzyme in the production of serotonin. While its use in patients with carcinoid syndrome and uncontrolled diarrhea unde...

journal_title：Neuroendocrinology

authors： Herrera-Martínez AD,Feelders RA,Van den Dungen R,Dogan-Oruc F,van Koetsveld PM,Castaño JP,de Herder WW,Hofland LJ

更新日期：2020-01-01 00:00:00

abstract：:The frequency of pulsatile release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) is high in the breeding season and low in the nonbreeding season. These alterations in the patterns of GnRH and LH release are due to an interaction of daylength and gonadal steroid negative feedback. A vast amount...

journal_title：Neuroendocrinology

authors： Dobbins A,Lubbers LS,Jackson GL,Kuehl DE,Hileman SM

更新日期：2004-02-01 00:00:00

abstract：:The purpose of these studies was to determine the temporal requirements and time of day required for progesterone (P4) to amplify versus extinguish LH surges. The experimental animal model used in these studies was the 7-day ovariectomized rat (day 0) treated continuously with estradiol (E2) for 2-4 days (days 2, 3 or...

journal_title：Neuroendocrinology

authors： Barraclough CA,Camp P,Weiland N,Akabori A

更新日期：1986-01-01 00:00:00

abstract：:Vasopressin-containing neurosecretory cells are partly regulated by GABAergic neurons present both at the hypothalamic and the pituitary level. In the present work, we compared GABA effects on vasopressin release from posterior pituitaries of Sprague-Dawley (SPD), Wistar (W), Wistar-Kyoto (WKY) and spontaneously hyper...

journal_title：Neuroendocrinology

authors： Magnusson AM,Meyerson BJ

更新日期：1993-11-01 00:00:00