Epitope mapping of monoclonal antibodies against human immunodeficiency virus type 1 structural proteins by using peptides.

abstract：:Vilyuisk human encephalitis virus (VHEV) is a picornavirus related to Theiler's murine encephalomyelitis virus (TMEV). VHEV was isolated from human material passaged in mice. Whether this VHEV is of human or mouse origin is therefore unclear. We took advantage of the species-specific activity of the nonstructural L* p...

journal_title：Journal of virology

authors： Drappier M,Opperdoes FR,Michiels T

更新日期：2017-06-26 00:00:00

abstract：:The putative role of nitric oxide in the neuropathogenesis of Borna disease was investigated by determining changes in the expression of inducible nitric oxide synthase (iNOS) mRNA and constitutively expressed NOS (cNOS) mRNA in brains of Borna disease virus (BDV)-infected rats. iNOS mRNA was not detected in normal ra...

journal_title：Journal of virology

authors： Zheng YM,Schäfer MK,Weihe E,Sheng H,Corisdeo S,Fu ZF,Koprowski H,Dietzschold B

更新日期：1993-10-01 00:00:00

abstract：:Recently, recombinant baculoviruses have been used to show that expression of six herpes simplex virus type 1 genes results in the formation of capsid-like particles. We have applied cryoelectron microscopy and three-dimensional image reconstruction to establish their structural authenticity to a resolution of approxi...

journal_title：Journal of virology

authors： Trus BL,Homa FL,Booy FP,Newcomb WW,Thomsen DR,Cheng N,Brown JC,Steven AC

更新日期：1995-11-01 00:00:00

abstract：:Sulfation is a posttranslational modification of proteins which occurs on either the tyrosine residues or the carbohydrate moieties of some glycoproteins. In the case of secretory proteins, sulfation has been hypothesized to act as a signal for export from the cell. We have shown that the human immunodeficiency virus ...

journal_title：Journal of virology

authors： Bernstein HB,Compans RW

更新日期：1992-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) reorganizes intracellular membranes to establish sites of replication. How viral and cellular proteins target, bind, and rearrange specific membranes into the replication factory remains a mystery. We used a lentivirus-based RNA interference (RNAi) screening approach to identify the potential c...

journal_title：Journal of virology

authors： Chao TC,Su WC,Huang JY,Chen YC,Jeng KS,Wang HD,Lai MM

更新日期：2012-02-01 00:00:00

abstract：:Mouse-hamster somatic cell hybrids were used to show that the recombinant mink cell focus-forming murine leukemia viruses and their ecotropic virus progenitors require different mouse chromosomes for replication. Mouse chromosome 1 was shown to carry the genetic information necessary for the replication of six differe...

journal_title：Journal of virology

authors： Kozak CA

更新日期：1983-10-01 00:00:00

abstract：:Three monkeypox virus (MPV) antibody-secreting murine monoclones were characterized as being of the immunoglobulin G1 isotype, gave a 4+ reaction in the indirect fluorescent-antibody test, gave a positive reaction in the enzyme immunoassay, and did not neutralize MPV. These monoclonal antibodies were determined by the...

journal_title：Journal of virology

authors： Roumillat LF,Patton JL,Davis ML

更新日期：1984-10-01 00:00:00

abstract：:Lipoxins are host anti-inflammatory molecules that play a vital role in restoring tissue homeostasis. The efficacy of lipoxins and their analog epilipoxins in treating inflammation and its associated diseases has been well documented. Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL) are two well-known inflamm...

journal_title：Journal of virology

authors： Chandrasekharan JA,Huang XM,Hwang AC,Sharma-Walia N

更新日期：2016-11-28 00:00:00

abstract：:Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV), a positive-strand RNA virus that belongs to the Arteriviridae family of Nidovirales, has been identified as the causative agent of PRRS. Nsp1alpha is the amino (N)-terminal protein in a polyprotein encoded by the PRRSV genome and is reported to be cru...

journal_title：Journal of virology

authors： Sun Y,Xue F,Guo Y,Ma M,Hao N,Zhang XC,Lou Z,Li X,Rao Z

更新日期：2009-11-01 00:00:00

abstract：:By using an isothermal multiply primed rolling-circle amplification protocol, the complete genomic DNA of a novel papillomavirus was amplified from a skin lesion biopsy of a Florida manatee (Trichechus manatus latirostris), one of the most endangered marine mammals in United States coastal waters. The nucleotide seque...

journal_title：Journal of virology

authors： Rector A,Bossart GD,Ghim SJ,Sundberg JP,Jenson AB,Van Ranst M

更新日期：2004-11-01 00:00:00

abstract：:Influenza virus particles bind rapidly to vesicular stomatitis, Sindbis, or Rauscher murine leukemia virus particles, forming mixed aggregates demonstrable by electron microscopy. The normal hemagglutinating property of influenza virus is inhibited by these viruses, providing a rapid quantitative assay. Prior treatmen...

journal_title：Journal of virology

authors： Compans RW

更新日期：1974-11-01 00:00:00

abstract：:The complete genome sequences of the human coronavirus OC43 (HCoV-OC43) laboratory strain from the American Type Culture Collection (ATCC), and a HCoV-OC43 clinical isolate, designated Paris, were obtained. Both genomes are 30,713 nucleotides long, excluding the poly(A) tail, and only differ by 6 nucleotides. These si...

journal_title：Journal of virology

authors： St-Jean JR,Jacomy H,Desforges M,Vabret A,Freymuth F,Talbot PJ

更新日期：2004-08-01 00:00:00

abstract：:Hepatitis A virus (HAV) 3C proteinase expressed in Escherichia coli was purified to homogeneity, and its cleavage specificity towards various parts of the viral polyprotein was analyzed. Intermolecular cleavage of the P2-P3 domain of the HAV polyprotein gave rise to proteins 2A, 2B, 2C, 3ABC, and 3D, suggesting that i...

journal_title：Journal of virology

authors： Schultheiss T,Sommergruber W,Kusov Y,Gauss-Müller V

更新日期：1995-03-01 00:00:00

abstract：:Echovirus 1 (EV1) is a human pathogen which belongs to the Picornaviridae family of RNA viruses. We have analyzed the early events of infection after EV1 binding to its receptor alpha 2 beta 1 integrin and elucidated the route by which EV1 gains access to the host cell. EV1 binding onto the cell surface and subsequent...

journal_title：Journal of virology

authors： Marjomäki V,Pietiäinen V,Matilainen H,Upla P,Ivaska J,Nissinen L,Reunanen H,Huttunen P,Hyypiä T,Heino J

更新日期：2002-02-01 00:00:00

abstract：:Chronic infections with viruses such as hepatitis B virus, hepatitis C virus, and HIV constitute a major global public health problem. Studies of chronic viral infections in humans and mice show that persistent antigenic stimulation induces dysregulation of T cell responses; virus-specific T cells either undergo clona...

journal_title：Journal of virology

authors： Sullivan JA,Kim EH,Plisch EH,Suresh M

更新日期：2012-09-01 00:00:00

abstract：:One hundred thirty-eight new Epstein-Barr virus (EBV) genome sequences have been determined. One hundred twenty-five of these and 116 from previous reports were combined to produce a multiple-sequence alignment of 241 EBV genomes, which we have used to analyze variation within the viral genome. The type 1/type 2 class...

journal_title：Journal of virology

authors： Correia S,Bridges R,Wegner F,Venturini C,Palser A,Middeldorp JM,Cohen JI,Lorenzetti MA,Bassano I,White RE,Kellam P,Breuer J,Farrell PJ

更新日期：2018-10-29 00:00:00

abstract：:Viral particles purified from species of the protozoan parasite Leishmania braziliensis subsp. guyanensis by centrifugation in CsCl gradients were examined for the presence of viral polymerase. We demonstrated that RNA-dependent RNA polymerase is associated with viral particles. Viral transcription was studied in vitr...

journal_title：Journal of virology

authors： Widmer G,Keenan MC,Patterson JL

更新日期：1990-08-01 00:00:00

abstract：:We have used cDNA arrays to compare the activation of various cellular genes in response to infection with Sendai viruses (SeV) that contain specific mutations. Three groups of cellular genes activated by mutant SeV infection, but not by wild-type SeV, were identified in this way. While some of these genes are well kn...

journal_title：Journal of virology

authors： Strähle L,Garcin D,Le Mercier P,Schlaak JF,Kolakofsky D

更新日期：2003-07-01 00:00:00

abstract：:Human CD317 (BST-2/tetherin) is an intrinsic immunity factor that blocks the release of retroviruses, filoviruses, herpesviruses, and arenaviruses. It is unclear whether CD317 expressed endogenously in rodent cells has the capacity to interfere with the replication of the retroviral rodent pathogen murine leukemia vir...

journal_title：Journal of virology

authors： Goffinet C,Schmidt S,Kern C,Oberbremer L,Keppler OT

更新日期：2010-11-01 00:00:00

abstract：:An infectious cDNA clone of a genotype 3 strain of hepatitis E virus adapted to growth in HepG2/C3A human hepatoma cells was constructed. This virus was unusual in that the hypervariable region of the adapted virus contained a 171-nucleotide insertion that encoded 58 amino acids of human S17 ribosomal protein. Analyse...

journal_title：Journal of virology

authors： Shukla P,Nguyen HT,Faulk K,Mather K,Torian U,Engle RE,Emerson SU

更新日期：2012-05-01 00:00:00

abstract：:The number of synonymous mutations per synonymous site (K(s)), the number of nonsynonymous mutations per nonsynonymous site (K(a)), and the codon usage statistic (N(c)) were calculated for several hepatitis A virus (HAV) isolates. While K(s) was similar to those of poliovirus (PV) and foot-and-mouth disease virus (FMD...

journal_title：Journal of virology

authors： Sánchez G,Bosch A,Pintó RM

更新日期：2003-01-01 00:00:00

abstract：:The yield of G418-resistant Huh7 cell clones bearing subgenomic dicistronic GB virus B (GBV-B) is significantly affected by the insertion of a portion of the viral core gene between the GBV-B 5' untranslated region and the exogenous neomycin phosphotransferase selector gene (A. De Tomassi, M. Pizzuti, R. Graziani, A. ...

journal_title：Journal of virology

authors： Pizzuti M,De Tomassi A,Traboni C

更新日期：2003-07-01 00:00:00

abstract：:The complete genomic sequence of a new Muscovy duck-origin reovirus (N-MDRV), strain J18 from China, was determined. The virus has a tricistronic S1 genome segment that is distinct from the originally described MDRV, which possesses a bicistronic S4 genome segment. Pairwise comparisons and phylogenetic analyses sugges...

journal_title：Journal of virology

authors： Wang D,Xu F,Ma G,Zhang C,Huang Y,Li H,Zhang D

更新日期：2012-11-01 00:00:00

abstract：:Alfalfa mosaic virus (AMV) and ilarvirus RNAs are infectious only in the presence of the viral coat protein; therefore, an understanding of coat protein's function is important for defining viral replication mechanisms. Based on in vitro replication experiments, the conformational switch model states that AMV coat pro...

journal_title：Journal of virology

authors： Guogas LM,Laforest SM,Gehrke L

更新日期：2005-05-01 00:00:00

abstract：:The avian sarcoma and leukosis virus (ASLV) family of retroviruses contains five highly related envelope subgroups (A to E) thought to have evolved from a common viral ancestor in the chicken population. Three genetic loci in chickens determine the susceptibility or resistance of cells to infection by the subgroup A t...

journal_title：Journal of virology

authors： Reinisová M,Senigl F,Yin X,Plachy J,Geryk J,Elleder D,Svoboda J,Federspiel MJ,Hejnar J

更新日期：2008-03-01 00:00:00

abstract：:Genetic and biochemical studies have suggested the existence of a bacteriophage-like, DNA-packaging/ejecting portal complex in herpesviruses capsids, but its arrangement remained unknown. Here, we report the first visualization of a unique vertex in the Kaposi's sarcoma-associated herpesvirus (KSHV) capsid by cryoelec...

journal_title：Journal of virology

authors： Deng B,O'Connor CM,Kedes DH,Zhou ZH

更新日期：2007-04-01 00:00:00

abstract：:We have found that the burst size of bacteriophage T7 was decreased in two Escherichia coli temperature-sensitive gyrase mutants incubated at the restrictive temperature. This reduction in burst size indicates that gyrase may be required for T7 growth. ...

journal_title：Journal of virology

authors： Steck TR,Drlica K

更新日期：1985-01-01 00:00:00

abstract：:The early proteins of simian virus 40 (SV40) large T and small t antigen (T/t antigen) can each cause the transcriptional activation of a variety of cellular and viral promoters. We showed previously that simian cellular DNA-binding factors (the Band A factors) bind to sequences within the SV40 late promoter which are...

journal_title：Journal of virology

authors： Gallo GJ,Gruda MC,Manuppello JR,Alwine JC

更新日期：1990-01-01 00:00:00

abstract：:We have previously characterized five proteins induced by the presence of the E2 open reading frame (ORF) region of bovine papillomavirus type 1 (BPV-1) in C127 mouse fibroblasts (R. M. Levenson, U. G. Brinckmann, M. K. O'Banion, E. J. Androphy, J. T. Schiller, F. Tabatabai, L. P. Turek, K. Neary, M. T. Chin, T. R. Br...

journal_title：Journal of virology

authors： O'Banion MK,Young DA

更新日期：1991-07-01 00:00:00

abstract：:Infection of neonatal mice with lymphocytic choriomeningitis virus (LCMV) strain Armstrong (ARM) results in a lifelong persistent infection. Viral variants (cytotoxic T lymphocyte [CTL] negative, persistence positive [CTL- P+]) can be isolated from the lymphoid tissues of such mice. Adult mice inoculated with these CT...

journal_title：Journal of virology

authors： Evans CF,Borrow P,de la Torre JC,Oldstone MB

更新日期：1994-11-01 00:00:00