Increased hippocampal excitability and impaired spatial memory function in mice lacking VGLUT2 selectively in neurons defined by tyrosine hydroxylase promoter activity.

abstract：:Brain connectivity in non-human primates (NHPs) has been mainly investigated using tracer techniques and functional connectivity studies. Data on structural connections are scarce and come from diffusion tensor imaging (DTI), since gross anatomical white matter dissection studies in the NHP are lacking. The current st...

journal_title：Brain structure & function

authors： Decramer T,Swinnen S,van Loon J,Janssen P,Theys T

更新日期：2018-11-01 00:00:00

abstract：:Substance used during adolescent period increases the risk of psychiatric disorders in later life, but the underlying neural mechanisms remain unclear. We hypothesize that synaptic remodeling and changes of homeostasis in the medial prefrontal cortex (mPFC) following adolescent cocaine exposure may last for a long tim...

journal_title：Brain structure & function

authors： Zhu W,Ge X,Gao P,Li M,Guan Y,Guan X

更新日期：2018-05-01 00:00:00

abstract：:Distribution of bromodeoxyuridine immunoreactive (BrdU-IR) cell nuclei was analyzed at proximal and remote cortical sites in adult Cebus apella monkeys after a programmed surgical lesion placed either in the prefrontal or in the striate cerebral cortex. Increased GFAP-IR and vimentin-IR astrocytes, as well as Isolecti...

journal_title：Brain structure & function

authors： Lanosa XA,Yáñez A,Alzugaray S,Colombo JA

更新日期：2012-04-01 00:00:00

abstract：:Dopaminergic neuromodulation is critically important for brain and cognitive integrity. The DRD2/ANKK1 Taq1A polymorphism is associated with striatal dopamine (DA) D2 receptor availability. Some previous studies have found that the A allele of the Taq1A polymorphism influences brain structure, but the results are inco...

journal_title：Brain structure & function

authors： Li X,Papenberg G,Kalpouzos G,Bäckman L,Persson J

更新日期：2018-07-01 00:00:00

abstract：:Using sinusoidal oscillations of linear acceleration along both the horizontal and vertical planes to stimulate otolith organs in the inner ear, we charted the postnatal time at which responsive neurons in the rat inferior olive (IO) first showed Fos expression, an indicator of neuronal recruitment into the otolith ci...

journal_title：Brain structure & function

authors： Li C,Han L,Ma CW,Lai SK,Lai CH,Shum DK,Chan YS

更新日期：2013-07-01 00:00:00

abstract：:Sex differences are widespread across vertebrate nervous systems. Such differences are sometimes reflected in the neural substrate via neuroanatomical differences in brain region volume. One brain region that displays sex differences in its associated functions and pathologies is the striatum, including the caudate-pu...

journal_title：Brain structure & function

authors： Wong JE,Cao J,Dorris DM,Meitzen J

更新日期：2016-11-01 00:00:00

abstract：:In the neocortex, large layer 5B pyramidal neurons implement a high-density firing code. In contrast, other subtypes of pyramidal neurons, including those in layer 2/3, are functionally characterized by their sparse firing rate. Here, we investigate the synaptic basis of this behavior by comparing the properties of th...

journal_title：Brain structure & function

authors： Sempere-Ferràndez A,Martínez S,Geijo-Barrientos E

更新日期：2019-05-01 00:00:00

abstract：:Several studies have begun to demonstrate that contextual memories constitute an important mechanism to guide our attention. Although there is general consensus that the hippocampus is involved in the encoding of contextual memories, it is controversial whether this structure can support implicit forms of contextual m...

journal_title：Brain structure & function

authors： Rosero MA,Winkelmann T,Pohlack S,Cavalli J,Nees F,Flor H

更新日期：2019-07-01 00:00:00

abstract：:Functional connectivity (FC) reflects the coherence of spontaneous, low-frequency fluctuations in functional magnetic resonance imaging (fMRI) data. We report a behavior-based connectivity analysis method, in which whole-brain data are used to identify behaviorally relevant, intrinsic FC networks. Nineteen younger adu...

journal_title：Brain structure & function

authors： Chen NK,Chou YH,Song AW,Madden DJ

更新日期：2009-10-01 00:00:00

abstract：:The medial prefrontal cortex (mPFC) has been associated with diverse functions including attentional processes, visceromotor activity, decision making, goal directed behavior, and working memory. Using retrograde tracing techniques, we examined, compared, and contrasted afferent projections to the four divisions of th...

journal_title：Brain structure & function

authors： Hoover WB,Vertes RP

更新日期：2007-09-01 00:00:00

abstract：:Similar to memory formation, memory extinction is also a new learning process that requires synaptic plasticity. Actin rearrangement is fundamental for synaptic plasticity, however, whether actin rearrangement in the infralimbic cortex (IL) plays a role in memory extinction, as well as the mechanisms underlying it, re...

journal_title：Brain structure & function

authors： Bi AL,Wang Y,Zhang S,Li BQ,Sun ZP,Bi HS,Chen ZY

更新日期：2015-03-01 00:00:00

abstract：:Von Economo's neurons (VENs) are large, bipolar or corkscrew-shaped neurons located in layers III and V of the frontoinsular and the anterior cingulate cortices. VENs are reported to be altered in pathologies such as frontotemporal dementia and autism, in which the individual's self control is seriously compromised. T...

journal_title：Brain structure & function

authors： Cauda F,Torta DM,Sacco K,D'Agata F,Geda E,Duca S,Geminiani G,Vercelli A

更新日期：2013-01-01 00:00:00

abstract：:Cerebellar volume declines with aging. Few studies have investigated age differences in regional cerebellar volume (RCV) and their association with motor and cognitive function. In 213 healthy older adults, we investigated the association of age with motor skills, cognition and RCV. Subsequently, we studied the associ...

journal_title：Brain structure & function

authors： Koppelmans V,Hoogendam YY,Hirsiger S,Mérillat S,Jäncke L,Seidler RD

更新日期：2017-05-01 00:00:00

abstract：:Finding the neuroanatomical correlates of prematurity is vital to understanding which structures are affected, and to designing efficient prevention and treatment strategies. Converging results reveal that thalamic abnormalities are important indicators of prematurity. However, little is known about the localization o...

journal_title：Brain structure & function

authors： Lao Y,Wang Y,Shi J,Ceschin R,Nelson MD,Panigrahy A,Leporé N

更新日期：2016-01-01 00:00:00

abstract：:The functional specificity of brain areas is diminished with age and accompanied by the recruitment of additional brain regions in healthy older adults. This process has repeatedly been demonstrated within distinct functional domains, in particular the visual system. However, it is yet unclear, whether this phenomenon...

journal_title：Brain structure & function

authors： Roski C,Caspers S,Lux S,Hoffstaedter F,Bergs R,Amunts K,Eickhoff SB

更新日期：2014-03-01 00:00:00

abstract：:A rapidly increasing number of studies are quantifying the system-level network architecture of the human brain based on structural-to-structural and functional-to-functional relationships. However, a largely unexplored area is the nature and existence of "cross-modal" structural-functional relationships, in which, fo...

journal_title：Brain structure & function

authors： Harms MP,Wang L,Csernansky JG,Barch DM

更新日期：2013-01-01 00:00:00

abstract：:Electrical stimulation of the dorsolateral periaqueductal gray (dlPAG) in rats has been shown to elicit panic-like behaviour and can be a useful as an unconditioned stimulus for modelling anticipatory fear and agoraphobia in a contextual fear conditioning paradigm. In this study, we further analysed our previous data ...

journal_title：Brain structure & function

authors： Tan SZK,Temel Y,Chan AY,Mok ATC,Perucho JAU,Blokland A,Aquili L,Lim WL,Lim LW

更新日期：2020-09-01 00:00:00

abstract：:An account of work performed at the UNA laboratories since 1992 on the detection and description of interlaminar glial processes, is presented. The incidental observation (serendipity) of longer than expected glial processes in the superficial layers of the cerebral cortex in hemiparkinsonian Cebus apella monkeys, was...

journal_title：Brain structure & function

authors： Colombo JA

更新日期：2017-04-01 00:00:00

abstract：:The frontal cortico-basal ganglia network plays a central role in action selection, associative learning, and motivation, processes requiring the integration of information from functionally distinct cortical regions. The cortico-striatal projection is a likely substrate of information integration, as terminal fields ...

journal_title：Brain structure & function

authors： Heilbronner SR,Meyer MAA,Choi EY,Haber SN

更新日期：2018-07-01 00:00:00

abstract：:The organization of the pallial derivatives across vertebrates follows a comparable elementary arrangement, although not all of them possess a layered cortical structure as sophisticated as the cerebral cortex of mammals. However, its expansion along evolution has only been possible by the development and coevolution ...

journal_title：Brain structure & function

authors： Jiménez S,López JM,Lozano D,Morona R,González A,Moreno N

更新日期：2020-09-01 00:00:00

abstract：:Glutamatergic afferents from the cerebral cortex are the main excitatory drive of striatal projection neurons. The metabotropic glutamate receptor 4 (mGluR4) presynaptically modulates transmission at corticostriatal synapses, and is considered as a potent drug target for Parkinson's disease and other brain disorders. ...

journal_title：Brain structure & function

authors： Iskhakova L,Smith Y

更新日期：2016-12-01 00:00:00

abstract：:Anterior cingulate cortex (ACC) input to the claustrum is required for top-down cognitive control of action. By virtue of its widespread cortical connectivity, the claustrum is anatomically situated to process and broadcast top-down signals from ACC to downstream cortices. To gain a deeper understanding of claustrum p...

journal_title：Brain structure & function

authors： White MG,Mathur BN

更新日期：2018-12-01 00:00:00

abstract：:We analyzed the developmental history of the subplate and related cellular compartments of the prenatal and early postnatal human cerebrum by combining postmortem histological analysis with in vivo MRI. Histological analysis was performed on 21 postmortem brains (age range: 26 postconceptional weeks to 6.5 years) usin...

journal_title：Brain structure & function

authors： Kostović I,Jovanov-Milošević N,Radoš M,Sedmak G,Benjak V,Kostović-Srzentić M,Vasung L,Čuljat M,Radoš M,Hüppi P,Judaš M

更新日期：2014-01-01 00:00:00

abstract：:Exercise (physical activity) has been proposed as a treatment for drug addiction. In rodents, voluntary wheel running reduces cocaine and nicotine seeking during extinction, and reinstatement of cocaine seeking triggered by drug-cues. The purpose of this study was to examine the effects of chronic wheel running during...

journal_title：Brain structure & function

authors： Sobieraj JC,Kim A,Fannon MJ,Mandyam CD

更新日期：2016-01-01 00:00:00

abstract：:The amygdala in mammals plays a key role in emotional processing and learning, being subdivided in pallial and subpallial derivatives. Recently, the cortical ring model and the pallial amygdalar radial model (Puelles et al. 2019; Garcia-Calero et al. 2020) described the pallial amygdala as an histogenetic field extern...

journal_title：Brain structure & function

authors： Garcia-Calero E,Puelles L

更新日期：2021-01-30 00:00:00

abstract：:Achievement motivation can be defined as a recurrent need to improve one's past performance. Despite previous functional imaging studies on motivation-related functional activation, the relationship between regional gray matter (rGM) morphology and achievement motivation has never been investigated. We used voxel-base...

journal_title：Brain structure & function

authors： Takeuchi H,Taki Y,Nouchi R,Sekiguchi A,Kotozaki Y,Miyauchi CM,Yokoyama R,Iizuka K,Hashizume H,Nakagawa S,Kunitoki K,Sassa Y,Kawashima R

更新日期：2014-01-01 00:00:00

abstract：:The medial septum and diagonal band of Broca (MSDB) influence hippocampal function through cholinergic, GABAergic, and glutamatergic septohippocampal neurons. Non-selective damage of the MSDB or intraseptal scopolamine impairs classical conditioning of the eyeblink response (CCER). Scopolamine preferentially inhibits ...

journal_title：Brain structure & function

authors： Roland JJ,Janke KL,Servatius RJ,Pang KC

更新日期：2014-07-01 00:00:00

abstract：:Normally, we are aware that our arms and legs belong to us and not to someone else. However, some stroke patients with hemiparesis/-plegia after right-sided stroke show a disturbed sensation of limb ownership and a disturbed self-awareness of actions and such patients with anosognosia for hemiparesis/plegia typically ...

journal_title：Brain structure & function

authors： Karnath HO,Baier B

更新日期：2010-06-01 00:00:00

abstract：:Emergence of advanced network analysis techniques utilizing resting-state functional magnetic resonance imaging (R-fMRI) has enabled a more comprehensive understanding of neurological disorders at a whole-brain level. However, inferring brain connectivity from R-fMRI is a challenging task, particularly when the ultima...

journal_title：Brain structure & function

authors： Wee CY,Yap PT,Zhang D,Wang L,Shen D

更新日期：2014-03-01 00:00:00

abstract：:The developing cerebellum is extremely vulnerable to hypoxia which can damage the Purkinje neurons. We hypothesized that this might be mediated by tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) derived from activated microglia as in other brain areas. One-day-old rats were subjected to hypoxia following, w...

journal_title：Brain structure & function

authors： Kaur C,Sivakumar V,Zou Z,Ling EA

更新日期：2014-01-01 00:00:00