Management of cystic prolactinomas: a review.

abstract：:Cushing's Syndrome (CS) is associated with an increased mortality, where hypercoagulability seems to have a crucial role in both arterial and venous thrombosis. Parameters of in vitro thrombin generation (TG) such as lag time, peak thrombin and endogenous thrombin potential (ETP), that describe the time until thrombin...

journal_title：Pituitary

authors： Koutroumpi S,Spiezia L,Albiger N,Barbot M,Bon M,Maggiolo S,Gavasso S,Simioni P,Frigo A,Mantero F,Scaroni C

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:Granular cell tumors of the neurohypophysis are rare, solitary lesions, mostly presenting in the adult age. They rarely grow to a sufficient size to cause mass effect related symptoms and they may be found in most cases incidentally at autopsy. Because of their rarity as of now they have been described only as ...

journal_title：Pituitary

authors： Gagliardi F,Spina A,Barzaghi LR,Bailo M,Losa M,Terreni MR,Mortini P

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:Thyrotropin-secreting pituitary adenoma is a rare disorder and was recently classified as an aggressive tumor in the World Health Organization guidelines. The number of available studies on cosecreting thyrotropin/growth hormone pituitary adenoma is especially limited. METHODS:A single-center retrospective ana...

journal_title：Pituitary

authors： Li X,Lynch L,Xing H,Wang Z,Zhu J,Deng K,Wang R,Yao Y,Lian X

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND/PURPOSE:During the early phase of sepsis, hypotension is accompanied by increase of plasma vasopressin hormone (AVP) levels, which decline during the late phase. This hypotension is due in part to increase of nitric oxide (NO) synthesis by nitric oxide synthase (NOS) enzyme. Neuronal isoform of this enzyme (...

journal_title：Pituitary

authors： Coelho CH,Martins TF,Oliveira-Pelegrin GR,da Rocha MJA

更新日期：2017-06-01 00:00:00

abstract：:Postoperative serum cortisol is used as an indicator of Cushing's disease (CD) remission following transsphenoidal surgery (TSS) and guides (controversially) the need for immediate adjuvant treatment for CD. We investigated postoperative cortisol and adrenocorticotropic hormone (ACTH) levels as predictors of remission...

journal_title：Pituitary

authors： Hameed N,Yedinak CG,Brzana J,Gultekin SH,Coppa ND,Dogan A,Delashaw JB,Fleseriu M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Autoimmune hypophysitis (AH) is a rare autoimmune inflammatory disorder of pituitary gland. OBJECTIVE:To analyse clinical, hormonal, radiological features and management outcomes of AH. DESIGN:Retrospective analysis of patients with primary hypophysitis (where secondary causes of hypophysitis were ruled ou...

journal_title：Pituitary

authors： Khare S,Jagtap VS,Budyal SR,Kasaliwal R,Kakade HR,Bukan A,Sankhe S,Lila AR,Bandgar T,Menon PS,Shah NS

更新日期：2015-02-01 00:00:00

abstract：:160 clinically non-secreting pituitary adenomas were examined in regard to their expression of the markers PCNA, bcl2, Ki 67 in the mib-1 modification and p53 which are still under investigation for their relevance to cell proliferation. The series contained 60 null cell adenomas, 60 oncocytomas and 40 gonadotroph ade...

journal_title：Pituitary

authors： Schreiber S,Saeger W,Lüdecke DK

更新日期：1999-05-01 00:00:00

abstract：CONTEXT:Octreotide causes significant tumour shrinkage in patients with acromegaly but the exact mechanism of action is unclear in vivo. OBJECTIVE:To determine the mechanism of action of octreotide in vivo using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). DESIGN:Five patients with acromegaly were ...

journal_title：Pituitary

authors： Sathyapalan T,Lowry M,Turnbull LW,Rowland-Hill C,Atkin SL

更新日期：2007-01-01 00:00:00

abstract：:A high incidence of venous thromboembolic (VTE) complications has been reported in Cushing's syndrome (CS), mostly post-operatively and attributable to hypercoagulability. The prevalence of symptomatic VTE was investigated retrospectively in 58 consecutive CS patients in relation to acquired and genetic thrombotic ris...

journal_title：Pituitary

authors： Koutroumpi S,Daidone V,Sartori MT,Cattini MG,Albiger NM,Occhi G,Ferasin S,Frigo A,Mantero F,Casonato A,Scaroni C

更新日期：2013-06-01 00:00:00

abstract：:We report on a 74-year-old male patient who presented with progressive neuroophthalmologic symptoms soon after the administration of a long-acting gonadotropin-releasing hormone agonist for treatment of a prostate cancer. Imaging revealed a destructively growing and extensively calcified sellar mass inconsistent with ...

journal_title：Pituitary

authors： Sahli R,Christ E,Kuhlen D,Giger O,Vajtai I

更新日期：2011-12-01 00:00:00

abstract：:The management of invasive giant prolactinomas (IGP) has been an area of some controversy. The relative roles of transsphenoidal surgery, craniotomy, radiation therapy and dopamine agonist based medical therapy are gradually becoming clarified. We report the results of management of 30 patients with IGP. Surgery was t...

journal_title：Pituitary

authors： Yu C,Wu Z,Gong J

更新日期：2005-01-01 00:00:00

abstract：:GH and IGF-1 play an important role in the regulation of metabolism and body composition. In patients with uncontrolled acromegaly, cardiovascular morbidity and mortality are increased but are supposed to be normalised after biochemical control is achieved. We aimed at comparing body composition and the cardiovascular...

journal_title：Pituitary

authors： Dimopoulou C,Sievers C,Wittchen HU,Pieper L,Klotsche J,Roemmler J,Schopohl J,Schneider HJ,Stalla GK

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:Doses of growth hormone in adults with growth hormone deficiency are now lower than previously. However, it is not clear they are as effective as higher doses. The objective of this meta-analysis was to assess efficacy of low to moderate dose (LD) GH replacement on standard endpoints of GH compared to higher do...

journal_title：Pituitary

authors： Newman CB,Carmichael JD,Kleinberg DL

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To determine the particle size, concentration, airborne duration and spread during endoscopic endonasal pituitary surgery in actual patients in a theatre setting. METHODS:This observational study recruited a convenience sample of three patients. Procedures were performed in a positive pressure operating room. ...

journal_title：Pituitary

authors： Dhillon RS,Nguyen LV,Rowin WA,Humphries RS,Kevin K,Ward JD,Yule A,Phan TD,Zhao YC,Wynne D,McNeill PM,Hutchins N,Scott DA

更新日期：2021-01-19 00:00:00

abstract：INTRODUCTION:Cushing's syndrome (CS) is a rare disease characterized by a collection of signs and symptoms, also common in the general population without elevated cortisol secretion. During the last years more patients with CS are identified earlier and with milder disease. Many of these patients are diagnosed during s...

journal_title：Pituitary

authors： Shimon I

更新日期：2015-04-01 00:00:00

abstract：:We aimed to study the occurrence of acute-onset symptoms at initial presentation in a national Danish cohort of patients with childhood- or adult-onset craniopharyngioma, and to investigate potential risk factors for acute presentation. Medical records of 189 consecutive patients (39 children, 150 adults) presenting w...

journal_title：Pituitary

authors： Nielsen EH,Jørgensen JO,Bjerre P,Andersen M,Andersen C,Feldt-Rasmussen U,Poulsgaard L,Kristensen LØ,Astrup J,Jørgensen J,Laurberg P

更新日期：2013-12-01 00:00:00

abstract：:Acromegaly is caused by a somatotropinoma in the vast majority of the cases. These are monoclonal tumors that can occur sporadically or rarely in a familial setting. In the last few years, novel familial syndromes have been described and recent studies explored the landscape of somatic mutations in sporadic somatotrop...

journal_title：Pituitary

authors： Gadelha MR,Kasuki L,Korbonits M

更新日期：2017-02-01 00:00:00

abstract：:To study the currently available data of recurrence rates of functioning and nonfunctioning pituitary adenomas following surgical cure and to analyze associated predisposing factors, which are not well established. A systematic literature search was conducted using Medline, Embase, Web of Science and the Cochran Libra...

journal_title：Pituitary

authors： Roelfsema F,Biermasz NR,Pereira AM

更新日期：2012-03-01 00:00:00

abstract：:Traumatic brain injury (TBI) is an important public health problem with an increasing incidence in the last years. Relatively few cases are fatal; most individuals will survive and, in the long-term, the sequalae of TBI will include neuroendocrine dysfunctions with a much higher frequency than previously suspected. Pa...

journal_title：Pituitary

authors： Caputo M,Mele C,Prodam F,Marzullo P,Aimaretti G

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The growing interest in the molecular and genetic alterations of craniopharyngiomas (CPs) is embodied in recent studies revealing insights into the CP tumorigenesis and identifying novel molecular pathways amenable of targeted therapies. The actual impact of this new information, however, remains inconclusiv...

journal_title：Pituitary

authors： Prieto R,Pascual JM

更新日期：2018-08-01 00:00:00

abstract：:Growth hormone releasing hormone (GHRH) signals via G protein-coupled receptors (GHRH-R) to enhance intracellular Galphas/adenylyl cyclase/cAMP signaling, which in turn has positive effects on GH synthesis and release, as well as proliferation of the GH-producing cells of the anterior pituitary gland. Some GH-producin...

journal_title：Pituitary

authors： Kim E,Sohn S,Lee M,Park C,Jung J,Park S

更新日期：2005-01-01 00:00:00

abstract：:A diabetic acromegalic man, not cured after surgery and radiosurgery, received lanreotide i.m. with great clinical and biochemical improvement. He required NPH insulin (76 to 84 units/day) to control his diabetes mellitus. Thirty-six hours after changing to LAR-octreotide (20 mg i.m/month) he presented symptomatic hyp...

journal_title：Pituitary

authors： Webb SM,Ortega E,Rodríguez-Espinosa J,Mato ME,Corcoy R

更新日期：2001-09-01 00:00:00

abstract：:There are scant prospective studies defining improvements in critical outcome measures with hormone replacement in hypopituitarism secondary to brain injury. We review the tests of cognition and physical function and summarize their use for subjects that are deficient in anterior hormone production during anterior pit...

journal_title：Pituitary

authors： Beca SG,High WM Jr,Masel BE,Mossberg KA,Urban RJ

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To provide an overview of fundamental concepts in machine learning (ML), review the literature on ML applications in imaging analysis of pituitary tumors for the last 10 years, and highlight the future directions on potential applications of ML for pituitary tumor patients. METHOD:We presented an overview of t...

journal_title：Pituitary

authors： Saha A,Tso S,Rabski J,Sadeghian A,Cusimano MD

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Endogenous Cushing's syndrome (CS) is a rare disease that results from exposure to high levels of cortisol; Cushing's disease (CD) is the most frequent form of CS. Patients with CS suffer from a variety of comorbidities that increase the risk of mortality. Surgical resection of the disease-causing lesion is gen...

journal_title：Pituitary

authors： Fleseriu M,Castinetti F

更新日期：2016-12-01 00:00:00

abstract：:Ideal surgical treatment of craniopharyngiomas remains a major challenge for neurosurgeons. Craniopharyngiomas grow in the deep-seated hypothalamic area that is paramount for vegetative, emotional and endocrine function, and for maintaining worthwhile life. The benign histological nature of craniopharyngiomas belies t...

journal_title：Pituitary

authors： Honegger J,Tatagiba M

更新日期：2008-01-01 00:00:00

abstract：:Non-functioning pituitary neuroendocrine tumors do not cause endocrine symptoms related to hypersecretion of adenohypophyseal hormones and are clinically characterized by symptoms due to growing sellar tumor mass. Histopathological classification of this tumor group has always been challenging due to their heterogenei...

journal_title：Pituitary

authors： Manojlovic-Gacic E,Engström BE,Casar-Borota O

更新日期：2018-04-01 00:00:00

abstract：:Inferior petrosal sinus sampling (IPSS) of ACTH with CRH stimulation helps distinguish pituitary ACTH-dependent Cushing's syndrome from the ectopic ACTH syndrome (EAS). The usefulness of the paradoxical response of other pituitary hormones including prolactin to CRH remains controversial. Data from 33 IPSS procedures ...

journal_title：Pituitary

authors： Daousi C,Nixon T,Javadpour M,Hayden K,MacFarlane IA

更新日期：2010-06-01 00:00:00

abstract：:Anemia and other hematological abnormalities are common in patients with Sheehan's syndrome. The response of these abnormalities to replacement of thyroxine and glucocorticoids is not clear. The aim of the present study was to document the profile of hematological abnormalities and response to treatment in patients wi...

journal_title：Pituitary

authors： Laway BA,Mir SA,Bashir MI,Bhat JR,Samoon J,Zargar AH

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:Long-acting somatostatin analogs are one of the main classes of medical therapy used for acromegaly and most patients require ongoing treatment. Few studies have evaluated the long-term efficacy and safety of lanreotide depot beyond 2 years. The goal of this study was to provide a long-term longitudinal assessm...

journal_title：Pituitary

authors： Sagvand BT,Khairi S,Haghshenas A,Swearingen B,Tritos NA,Miller KK,Klibanski A,Nachtigall LB

更新日期：2016-08-01 00:00:00