Abstract:
:Acromegaly is caused by a somatotropinoma in the vast majority of the cases. These are monoclonal tumors that can occur sporadically or rarely in a familial setting. In the last few years, novel familial syndromes have been described and recent studies explored the landscape of somatic mutations in sporadic somatotropinomas. This short review concentrates on the current knowledge of the genetic basis of both familial and sporadic acromegaly.
journal_name
Pituitaryjournal_title
Pituitaryauthors
Gadelha MR,Kasuki L,Korbonits Mdoi
10.1007/s11102-017-0789-7subject
Has Abstractpub_date
2017-02-01 00:00:00pages
10-21issue
1eissn
1386-341Xissn
1573-7403pii
10.1007/s11102-017-0789-7journal_volume
20pub_type
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