Abstract:
:We report on a 74-year-old male patient who presented with progressive neuroophthalmologic symptoms soon after the administration of a long-acting gonadotropin-releasing hormone agonist for treatment of a prostate cancer. Imaging revealed a destructively growing and extensively calcified sellar mass inconsistent with a pituitary adenoma. A transseptal transsphenoidal tumor mass reduction yielded a histological diagnosis of a collision tumor comprised of a gonadotroph adenoma intermingled with osteochondroma. We discuss a potential causal relationship between the administration of the long-acting gonadotropin-releasing hormone agonist and the sudden appearance of the previously unsuspected sellar lesion. Although the association of these two tumors is very likely coincidental, the possibility of causal relationship is addressed.
journal_name
Pituitaryjournal_title
Pituitaryauthors
Sahli R,Christ E,Kuhlen D,Giger O,Vajtai Idoi
10.1007/s11102-009-0199-6subject
Has Abstractpub_date
2011-12-01 00:00:00pages
405-8issue
4eissn
1386-341Xissn
1573-7403journal_volume
14pub_type
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