Hematologic neoplasias and acromegaly.

abstract：:Non-functioning pituitary neuroendocrine tumors do not cause endocrine symptoms related to hypersecretion of adenohypophyseal hormones and are clinically characterized by symptoms due to growing sellar tumor mass. Histopathological classification of this tumor group has always been challenging due to their heterogenei...

journal_title：Pituitary

authors： Manojlovic-Gacic E,Engström BE,Casar-Borota O

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:Nelson's syndrome is a challenging condition that can develop following bilateral adrenalectomy for Cushing's disease, with high circulating ACTH levels, pigmentation and an invasive pituitary tumor. There is no established medical therapy. The aim of the study was to assess the effects of pasireotide on plasma...

journal_title：Pituitary

authors： Daniel E,Debono M,Caunt S,Girio-Fragkoulakis C,Walters SJ,Akker SA,Grossman AB,Trainer PJ,Newell-Price J

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:Severe fluctuations in plasma sodium concentration and plasma osmolarity, including central diabetes insipidus (CDI), may have significant influence on postoperative morbidity and mortality after pediatric brain tumor surgery.The aim of this study was to describe the frequency, severity and neurological consequ...

journal_title：Pituitary

authors： Kruis RWJ,Schouten-van Meeteren AYN,Finken MJJ,Oostdijk W,van Trotsenburg ASP,Boot AM,Claahsen-van der Grinten HL,van Lindert EJ,Han KS,Hoving EW,Michiels EMC,van Santen HM

更新日期：2018-08-01 00:00:00

abstract：:MAP-2, a well characterized member of the microtubule associated protein (MAP) family, binds to and stabilizes microtubules and is involved in cell proliferation as well as neuronal differentiation. The aim of the present work was to study MAP-2 expression in human adenohypophyses and pituitary adenomas. To our knowle...

journal_title：Pituitary

authors： Rotondo F,Oniya K,Kovacs K,Bell CD,Scheithauer BW

更新日期：2005-01-01 00:00:00

abstract：:We report the case of a B-cell type pituitary lymphoma in a 65 year-old male immunocompetent patient who presented with hypogonadotropic hypogonadism and central hypothyroidism and subsequently developed pulmonary lymphoma. Only three cases of pituitary lymphoma have been previously reported, one in a patient with acq...

journal_title：Pituitary

authors： Mathiasen RA,Jarrahy R,Cha ST,Kovacs K,Herman VS,Ginsberg E,Shahinian HK

更新日期：2000-05-01 00:00:00

abstract：:Surgical cure cannot be achieved in most patients with invasive non-functioning pituitary macroadenoma (NFPA). Short-term residual tumor treatment with somatostatin analogs has produced disappointing results. This prospective case-control study assessed the efficacy of chronic treatment with long acting octreotide (oc...

journal_title：Pituitary

authors： Fusco A,Giampietro A,Bianchi A,Cimino V,Lugli F,Piacentini S,Lorusso M,Tofani A,Perotti G,Lauriola L,Anile C,Maira G,Pontecorvi A,De Marinis L

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Suprasellar pituitary adenomas (SPAs) are a special type of pituitary adenoma. Although dozens of SPA cases have been reported, the exact definition and the characteristics of SPA have not been exhaustively discussed before. METHODS:In a retrospective electronic medical records review, 13 patients with SPA ...

journal_title：Pituitary

authors： Zhu J,Wang Z,Zhang Y,Liu J,Li X,Deng K,Lu L,Yao Y

更新日期：2020-08-01 00:00:00

abstract：:Oral estrogens reduce GH-induced IGF-1 production and preliminary studies have shown that adjuvant estroprogestin (EP) therapy with octreotide LAR may control disease activity in some female patients who are partially responsive to octreotide LAR. Our aim was to verify if EP alone or in combination with octreotide LAR...

journal_title：Pituitary

authors： Vallette S,Serri O

更新日期：2010-12-01 00:00:00

abstract：:Postoperative serum cortisol is used as an indicator of Cushing's disease (CD) remission following transsphenoidal surgery (TSS) and guides (controversially) the need for immediate adjuvant treatment for CD. We investigated postoperative cortisol and adrenocorticotropic hormone (ACTH) levels as predictors of remission...

journal_title：Pituitary

authors： Hameed N,Yedinak CG,Brzana J,Gultekin SH,Coppa ND,Dogan A,Delashaw JB,Fleseriu M

更新日期：2013-12-01 00:00:00

abstract：INTRODUCTION:Temozolomide (TMZ) is an oral alkylating agent that has been used over the past 8 years to treat aggressive pituitary tumors resistant to conventional therapy. To date, only 25 patients treated with TMZ for ACTH producing pituitary tumors (14 adenomas and 11 carcinomas) have been reported. MATERIALS AND M...

journal_title：Pituitary

authors： Campderá M,Palacios N,Aller J,Magallón R,Martín P,Saucedo G,Lilienfeld H,Estrada J

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Xanthogranulomas are inflammatory masses most commonly found at peripheral sites such as the skin. Sellar and parasellar xanthogranulomas are rare and present a diagnostic challenge as they are difficult to differentiate from other sellar lesions such as craniopharyngiomas and Rathke's cleft cysts pre-operat...

journal_title：Pituitary

authors： Ved R,Logier N,Leach P,Davies JS,Hayhurst C

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To determine the particle size, concentration, airborne duration and spread during endoscopic endonasal pituitary surgery in actual patients in a theatre setting. METHODS:This observational study recruited a convenience sample of three patients. Procedures were performed in a positive pressure operating room. ...

journal_title：Pituitary

authors： Dhillon RS,Nguyen LV,Rowin WA,Humphries RS,Kevin K,Ward JD,Yule A,Phan TD,Zhao YC,Wynne D,McNeill PM,Hutchins N,Scott DA

更新日期：2021-01-19 00:00:00

abstract：:Leptin is a key mediator in the maintenance of neuroendocrine homeostasis. The aim of this study was to determine the changes in serum leptin, tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), nitric oxide (NO) levels in patients with hyperprolactinemia. The study consists of 16 consecutive patients with ...

journal_title：Pituitary

authors： Balci H,Akgun-Dar K,Gazioglu N,Kapucu A,Bolayirli M,Oz B

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:The pituitary gland is an unusual site for metastatic spread, but as patients with metastatic malignancy are living longer, it may become more prevalent. Compression of important anatomy adjacent to the sella may produce disabling symptoms and endocrine derangement, leading to significant morbidity. METHODS:An...

journal_title：Pituitary

authors： Castle-Kirszbaum M,Goldschlager T,Ho B,Wang YY,King J

更新日期：2018-10-01 00:00:00

abstract：:Clinically inapparent adrenal masses, or adrenal incidentalomas, are discovered inadvertently in the course of workup or treatment of unrelated disorders. Cortical adenoma is the most frequent type of adrenal incidentaloma accounting for approximately 50% of cases in surgical series and even greater shares in medical ...

journal_title：Pituitary

authors： Terzolo M,Reimondo G,Bovio S,Angeli A

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To evaluate the effects of somatostatin analogs and disease activity status on the upper gastrointestinal system in patients with acromegaly. METHODS:One hundred eighty-one patients with acromegaly were retrospectively assessed. The demographic, biochemical, pathologic, and radiologic data of the patients were...

journal_title：Pituitary

authors： Sahin S,Icli TB,Durcan E,Sulu C,Ozkaya HM,Hatemi AI,Kadioglu P

更新日期：2020-10-19 00:00:00

abstract：INTRODUCTION:In order to perform trans-sphenoidal endoscopic pituitary surgery safely and efficiently it is important to identify anatomical and pituitary disease features on the pre-operative CT and MRI scans; thereby minimising the risk to surrounding structures and optimising outcomes. We aim to create a checklist t...

journal_title：Pituitary

authors： Twigg V,Carr SD,Balakumar R,Sinha S,Mirza S

更新日期：2017-08-01 00:00:00

abstract：:Pituitary cysts are usually craniopharyngiomas or remnants of Rathke's cleft. Histologically craniopharyngiomas are lined by stratified squamous epithelium whereas Rathke's cleft cysts are lined by cuboidal or columnar epithelium. The management of pituitary cysts remains difficult because of the risks associated with...

journal_title：Pituitary

authors： Dashora U,Mathias D,James A,Zammit-Maempel I,Perros P

更新日期：2002-01-01 00:00:00

abstract：:The modern views on the anatomical and physiological interactions between the hypothalamus, pituitary and thyroid gland have emerged only in the last fifty years, although their historical roots may be found in a number of ancient and still not widely known ideas and observations. The regulation of energy body stores ...

journal_title：Pituitary

authors： Toni R

更新日期：2000-10-01 00:00:00

abstract：:Meningiomas account for about 1% of sellar masses. Although they can mimic pituitary adenomas, they are more vascularized and invasive. To gain insights that would enhance our ability to establish a pre-surgical diagnosis of meningioma, we performed a retrospective study of these tumors. Query of the surgical patholog...

journal_title：Pituitary

authors： Kwancharoen R,Blitz AM,Tavares F,Caturegli P,Gallia GL,Salvatori R

更新日期：2014-08-01 00:00:00

abstract：INTRODUCTION:Autoimmune lymphocytic hypophysitis associates predominantly with other autoimmune endocrinopathies and is most commonly treated with glucocorticoids and/or decompressive pituitary surgery. Here we report a new association and treatment modality for lymphocytic hypophysitis. METHODS:A 52-year-old woman pr...

journal_title：Pituitary

authors： Xu C,Ricciuti A,Caturegli P,Keene CD,Kargi AY

更新日期：2015-08-01 00:00:00

abstract：:Lanreotide depot (LD; commercial name Somatuline(®) Depot) is an injectable, extended-release formulation of the synthetic somatostatin analog (SSA) lanreotide. In recent clinical trials, LD was found to be suitable for self or partner administration, avoiding the need to travel to a medical facility. The Somatuline(®...

journal_title：Pituitary

authors： Salvatori R,Woodmansee WW,Molitch M,Gordon MB,Lomax KG

更新日期：2014-02-01 00:00:00

abstract：:Double pituitary adenomas are rare in surgical specimens and the most common clinical feature in reported patients has been acromegaly. We report 3 cases of double pituitary lesions in patients who presented with Cushing's disease. In a 22-year-old man (case 1) with delayed puberty and low testosterone levels, mild hy...

journal_title：Pituitary

authors： Meij BP,Lopes MB,Vance ML,Thorner MO,Laws ER Jr

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:In a 10-week proof-of-concept study (LINC 1), the potent oral 11β-hydroxylase inhibitor osilodrostat (LCI699) normalized urinary free cortisol (UFC) in 11/12 patients with Cushing's disease. The current 22-week study (LINC 2; NCT01331239) further evaluated osilodrostat in patients with Cushing's disease. METHO...

journal_title：Pituitary

authors： Fleseriu M,Pivonello R,Young J,Hamrahian AH,Molitch ME,Shimizu C,Tanaka T,Shimatsu A,White T,Hilliard A,Tian C,Sauter N,Biller BM,Bertagna X

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:Ectopic pituitary adenomas (EPA) are rare tumors thought to arise from embryological remnants along the route of normal pituitary migration. Clinically, these tumors vary in hormonal activity and can exert mass effect based on location and size. METHODS:We performed a single-center retrospective analysis of pa...

journal_title：Pituitary

authors： Agely A,Okromelidze L,Vilanilam GK,Chaichana KL,Middlebrooks EH,Gupta V

更新日期：2019-08-01 00:00:00

abstract：:Pituitary radiotherapy (RT) is an effective second-line treatment for paediatric Cushing's disease (CD). We report long-term efficacy and anterior pituitary function in a cohort of paediatric CD patients treated with RT. Between 1988 and 2008, from our cohort of 48 paediatric CD patients, eight paediatric CD patients ...

journal_title：Pituitary

authors： Acharya SV,Gopal RA,Goerge J,Menon PS,Bandgar TR,Shah NS

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:Hypofractionated stereotactic radiotherapy (HSRT) for refractory Cushing's disease may offer a condensed treatment schedule for patients with large tumors abutting the optic chiasm unsuitable for stereotactic radiosurgery (SRS). To-date only four patients have been treated by HSRT in the published literature. W...

journal_title：Pituitary

authors： Sherry AD,Khattab MH,Xu MC,Kelly P,Anderson JL,Luo G,Utz AL,Chambless LB,Cmelak AJ,Attia A

更新日期：2019-12-01 00:00:00

abstract：:In western countries, the process of "ageing of the population" is increasingly forcing clinical medicine to find answers for pathologies affecting the elder segments of our community. In this respect, pituitary adenomas often raise difficult questions on surgical indications, since little is known about postoperative...

journal_title：Pituitary

authors： Locatelli M,Bertani G,Carrabba G,Rampini P,Zavanone M,Caroli M,Sala E,Ferrante E,Gaini SM,Spada A,Mantovani G,Lania A

更新日期：2013-06-01 00:00:00

abstract：:We describe two young men with cystic pituitary enlargement on magnetic resonance imaging (MRI) causing hypopituitarism. The first patient presented acutely unwell with headache and vomiting associated with anterior and posterior pituitary dysfunction. The second patient presented with hypopituitarism after a long his...

journal_title：Pituitary

authors： Burt MG,Morey AL,Turner JJ,Pell M,Sheehy JP,Ho KK

更新日期：2003-01-01 00:00:00

abstract：:The dexamethasone (DXM) test has been widely used for diagnosing Cushing's disease (CD). The purpose of this paper is to review its diagnostic merit based on calculation of data extracted from earlier publications. Studies presenting individual values for patients with CD and normal subjects were identified through Pu...

journal_title：Pituitary

authors： Lindholm J

更新日期：2014-08-01 00:00:00