Decreased insulin requirements after LAR-octreotide but not after lanreotide in an acromegalic patient.

abstract：:The simultaneous occurrence of a hypothalamic and sellar gangliocytoma with a pituitary prolactinoma is very rare. The explanation for such an association is not known. We describe the case of a woman who had a coexisting adjacent pituitary prolactinoma and gangliocytoma within the same sellar mass. The tumor cells of...

journal_title：Pituitary

authors： Serri O,Berthelet F,Bélair M,Vallette S,Asa SL

更新日期：2008-01-01 00:00:00

abstract：:In this case report we describe a 38 year-old-female with galactorrhea several months after the birth of an anencephalic child. She had hyperpolactemia and imaging of the pituitary gland revealed a midline defect and a nasopharyngeal mass compatible with a meningo-(hypophyso-) encephalocele and possibly an ectopic ter...

journal_title：Pituitary

authors： Rabelink NM,Lips P,Castelijns JA

更新日期：2012-12-01 00:00:00

abstract：:Primary autoimmune hypophysitis (PAH) is considered an underdiagnosed disease, due to the difficulty in reaching a definitive diagnosis. PAH clinical diagnosis remains an exclusion diagnosis. We aimed to correlate PAH neuro-radiological signs to endocrine features and evaluate their prognostic role. 24 PAH cases were ...

journal_title：Pituitary

authors： Tartaglione T,Chiloiro S,Laino ME,Giampietro A,Gaudino S,Zoli A,Bianchi A,Pontecorvi A,Colosimo C,De Marinis L

更新日期：2018-08-01 00:00:00

abstract：:Anemia and other hematological abnormalities are common in patients with Sheehan's syndrome. The response of these abnormalities to replacement of thyroxine and glucocorticoids is not clear. The aim of the present study was to document the profile of hematological abnormalities and response to treatment in patients wi...

journal_title：Pituitary

authors： Laway BA,Mir SA,Bashir MI,Bhat JR,Samoon J,Zargar AH

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:In this study, we set out to define our institutional criteria for patient eligibility for transsphenoidal resection of parasellar meningiomas, and to report our experience with extended transnasal approaches for these lesions. We aimed to discuss the important considerations of patient selection and risk strat...

journal_title：Pituitary

authors： Castlen JP,Cote DJ,Zaidi HA,Laws ER Jr

更新日期：2017-10-01 00:00:00

abstract：:Traumatic brain injury (TBI) is an important public health problem with an increasing incidence in the last years. Relatively few cases are fatal; most individuals will survive and, in the long-term, the sequalae of TBI will include neuroendocrine dysfunctions with a much higher frequency than previously suspected. Pa...

journal_title：Pituitary

authors： Caputo M,Mele C,Prodam F,Marzullo P,Aimaretti G

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Lymphocytic hypophysitis (LH) is a rare chronic inflammatory disorder characterized by lymphocytic infiltration of the pituitary gland commonly affecting women during pregnancy or post-partum period. The pathogenesis remains uncertain, however an autoimmune process is frequently implicated. There is limited d...

journal_title：Pituitary

authors： Lim S,Elston MS,Swarbrick MJ,Conaglen JV

更新日期：2009-01-01 00:00:00

abstract：:The role of pituitary radiotherapy (RT) in the management of clinically non-functioning pituitary tumors (NFTs) remains controversial. Observational studies suggest that RT is effective in preventing the regrowth of NFT remnants following initial surgical debulking. However, not all tumor remnants will regrow in the a...

journal_title：Pituitary

authors： Gittoes NJ

更新日期：2003-09-01 00:00:00

abstract：CONTEXT:Octreotide causes significant tumour shrinkage in patients with acromegaly but the exact mechanism of action is unclear in vivo. OBJECTIVE:To determine the mechanism of action of octreotide in vivo using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). DESIGN:Five patients with acromegaly were ...

journal_title：Pituitary

authors： Sathyapalan T,Lowry M,Turnbull LW,Rowland-Hill C,Atkin SL

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Endogenous Cushing's syndrome (CS) is a rare disease that results from exposure to high levels of cortisol; Cushing's disease (CD) is the most frequent form of CS. Patients with CS suffer from a variety of comorbidities that increase the risk of mortality. Surgical resection of the disease-causing lesion is gen...

journal_title：Pituitary

authors： Fleseriu M,Castinetti F

更新日期：2016-12-01 00:00:00

abstract：:Pituitary radiotherapy (RT) is an effective second-line treatment for paediatric Cushing's disease (CD). We report long-term efficacy and anterior pituitary function in a cohort of paediatric CD patients treated with RT. Between 1988 and 2008, from our cohort of 48 paediatric CD patients, eight paediatric CD patients ...

journal_title：Pituitary

authors： Acharya SV,Gopal RA,Goerge J,Menon PS,Bandgar TR,Shah NS

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Survival rates among childhood cancer survivors (CCSs) have significantly risen in the last 40 years due to substantial improvements in treatment protocols. However, this improvement has brought with it serious late effects that frequently involve the endocrine system. Of the endocrine disorders, GH deficien...

journal_title：Pituitary

authors： Sbardella E,Crocco M,Feola T,Papa F,Puliani G,Gianfrilli D,Isidori AM,Grossman AB

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To evaluate the effects of somatostatin analogs and disease activity status on the upper gastrointestinal system in patients with acromegaly. METHODS:One hundred eighty-one patients with acromegaly were retrospectively assessed. The demographic, biochemical, pathologic, and radiologic data of the patients were...

journal_title：Pituitary

authors： Sahin S,Icli TB,Durcan E,Sulu C,Ozkaya HM,Hatemi AI,Kadioglu P

更新日期：2020-10-19 00:00:00

abstract：PURPOSE:Secondary empty sella syndrome (SESS) following pituitary surgery remains a diagnostic and therapeutic challenge. The aim of this study was to specify the diagnostic criteria, surgical indications and results of chiasmapexy in the SESS. METHODS:Three cases from two experienced neurosurgical centers were collec...

journal_title：Pituitary

authors： Graillon T,Passeri T,Boucekine M,Meyer M,Abritti R,Bernat AL,Labidi M,Dufour H,Froelich S

更新日期：2020-11-02 00:00:00

abstract：:A high incidence of venous thromboembolic (VTE) complications has been reported in Cushing's syndrome (CS), mostly post-operatively and attributable to hypercoagulability. The prevalence of symptomatic VTE was investigated retrospectively in 58 consecutive CS patients in relation to acquired and genetic thrombotic ris...

journal_title：Pituitary

authors： Koutroumpi S,Daidone V,Sartori MT,Cattini MG,Albiger NM,Occhi G,Ferasin S,Frigo A,Mantero F,Casonato A,Scaroni C

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Approximately 25 % of cases of clinically active acromegaly cases treated in our academic center between 1996 and 2000, were diagnosed in patients who had elevated plasma IGF-1 levels, but apparently "normal" 24-h mean plasma GH levels. The current study served to update the data for patients with acromegaly re...

journal_title：Pituitary

authors： Butz LB,Sullivan SE,Chandler WF,Barkan AL

更新日期：2016-12-01 00:00:00

abstract：:Lanreotide depot (LD; commercial name Somatuline(®) Depot) is an injectable, extended-release formulation of the synthetic somatostatin analog (SSA) lanreotide. In recent clinical trials, LD was found to be suitable for self or partner administration, avoiding the need to travel to a medical facility. The Somatuline(®...

journal_title：Pituitary

authors： Salvatori R,Woodmansee WW,Molitch M,Gordon MB,Lomax KG

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:Recent guidelines suggest that a single prolactin measurement is adequate to confirm hyperprolactinaemia. This may lead to unnecessary investigation of artefactual hyperprolactinaemia. Prolactin measurement drawn from an indwelling cannula after rest removes stress as a confounding variable. The objective was t...

journal_title：Pituitary

authors： Whyte MB,Pramodh S,Srikugan L,Gilbert JA,Miell JP,Sherwood RA,McGregor AM,Aylwin SJ

更新日期：2015-06-01 00:00:00

abstract：:GH and IGF-1 play an important role in the regulation of metabolism and body composition. In patients with uncontrolled acromegaly, cardiovascular morbidity and mortality are increased but are supposed to be normalised after biochemical control is achieved. We aimed at comparing body composition and the cardiovascular...

journal_title：Pituitary

authors： Dimopoulou C,Sievers C,Wittchen HU,Pieper L,Klotsche J,Roemmler J,Schopohl J,Schneider HJ,Stalla GK

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:Survivin is an apoptosis inhibitor, expressed in almost all types of human malignancies, but rarely in differentiated normal tissues. Recently, survivin gene splice variants with different anti-apoptotic activities have been reported. The current study was undertaken to examine the expression of survivin and it...

journal_title：Pituitary

authors： Waligórska-Stachura J,Andrusiewicz M,Sawicka-Gutaj N,Kubiczak M,Jankowska A,Liebert W,Czarnywojtek A,Waśko R,Blanco-Gangoo AR,Ruchała M

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Somatostatin (SST) and dopamine (DA) inhibit growth hormone (GH) secretion and proliferation of GH-secreting pituitary adenomas (GHomas) through binding to SSTR2 and D2R receptors. Chimeric SST-DA compounds (Dopastatins) display increased potency in inhibiting GH secretion, as compared with individual SST or DA...

journal_title：Pituitary

authors： Cuny T,Graillon T,Defilles C,Datta R,Zhang S,Figarella-Branger D,Dufour H,Mougel G,Brue T,Landsman T,Halem HA,Culler MD,Barlier A,Saveanu A

更新日期：2021-01-12 00:00:00

abstract：INTRODUCTION:Cystic prolactinoma is a variant of prolactin-secreting pituitary adenoma. The strategies for the management of cystic prolactinoma have not been addressed thoroughly in clinical guidelines. METHODS:A literature search was performed using Pubmed to review the current approaches to the treatment of cystic ...

journal_title：Pituitary

authors： Nakhleh A,Shehadeh N,Hochberg I,Zloczower M,Zolotov S,Taher R,Daoud Naccache D

更新日期：2018-08-01 00:00:00

abstract：:Cis-unsaturated free fatty acids (FFA) like oleic acid are strong blockers of both basal and stimulated GH secretion in vivo by acting directly on the somatotroph cell. Several lines of evidence suggest that this inhibitory action is the result of a perturbation of the function of several plasma membrane integral prot...

journal_title：Pituitary

authors： Pérez FR,Camiña JP,Menéndez C,Beiras A,Casabiell X,Casanueva FF

更新日期：1998-04-01 00:00:00

abstract：PURPOSE:Ectopic pituitary adenomas (EPA) are rare tumors thought to arise from embryological remnants along the route of normal pituitary migration. Clinically, these tumors vary in hormonal activity and can exert mass effect based on location and size. METHODS:We performed a single-center retrospective analysis of pa...

journal_title：Pituitary

authors： Agely A,Okromelidze L,Vilanilam GK,Chaichana KL,Middlebrooks EH,Gupta V

更新日期：2019-08-01 00:00:00

abstract：:Most patients with acromegaly have some degree of insulin resistance. The principal mediator of insulin resistance in acromegaly is hypersecretion of growth hormone. Growth hormone acts at several levels to block insulin actions including inhibiting phosphorylation of the insulin receptor and one of its principal sign...

journal_title：Pituitary

authors： Clemmons DR

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:In order to perform trans-sphenoidal endoscopic pituitary surgery safely and efficiently it is important to identify anatomical and pituitary disease features on the pre-operative CT and MRI scans; thereby minimising the risk to surrounding structures and optimising outcomes. We aim to create a checklist t...

journal_title：Pituitary

authors： Twigg V,Carr SD,Balakumar R,Sinha S,Mirza S

更新日期：2017-08-01 00:00:00

abstract：:160 clinically non-secreting pituitary adenomas were examined in regard to their expression of the markers PCNA, bcl2, Ki 67 in the mib-1 modification and p53 which are still under investigation for their relevance to cell proliferation. The series contained 60 null cell adenomas, 60 oncocytomas and 40 gonadotroph ade...

journal_title：Pituitary

authors： Schreiber S,Saeger W,Lüdecke DK

更新日期：1999-05-01 00:00:00

abstract：:Twenty years after the first description of combined hypopituitarism (CPHD) caused by PROP1 mutations, the phenotype of affected subjects is still challenging for clinicians. These patients suffer from pituitary hormone deficits ranging from IGHD to panhypopituitarism. ACTH deficiency usually develops later in life. P...

journal_title：Pituitary

authors： Doknic M,Gasic V,Stojanovic M,Pavlovic S,Marinkovic S,Miljic D,Pekic S,Manojlovic-Gacic E,Damjanovic D,Soldatovic I,Petakov M

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To provide an overview of fundamental concepts in machine learning (ML), review the literature on ML applications in imaging analysis of pituitary tumors for the last 10 years, and highlight the future directions on potential applications of ML for pituitary tumor patients. METHOD:We presented an overview of t...

journal_title：Pituitary

authors： Saha A,Tso S,Rabski J,Sadeghian A,Cusimano MD

更新日期：2020-06-01 00:00:00

abstract：:The metabolic consequences of thyroxine replacement in patients with central hypothyroidism (CH) need to be evaluated. The aim was to examine the outcome of thyroxine replacement in CH. Adult hypopituitary patients (n = 1595) with and without CH from KIMS (Pfizer International Metabolic Database) were studied before a...

journal_title：Pituitary

authors： Filipsson Nyström H,Feldt-Rasmussen U,Kourides I,Popovic V,Koltowska-Häggström M,Jonsson B,Johannsson G

更新日期：2012-12-01 00:00:00