Abstract:
:A new exopolysaccharide preparation isolated from stationary cultures of the white rot fungus Ganoderma applanatum (GpEPS) was tested in terms of its bioactive properties including its cytotoxic and immunostimulatory effect. The results indicate that the tested GpEPS (at concentrations above 22.85 µg/mL and 228.5 µg/mL) may exhibit selective activity against tumor cells (cell lines SiHa) and stimulate production of TNF-α THP-1-derived macrophages at the level of 752.17 pg/mL. The GpEPS showed antibacterial properties against Staphyloccoccus aureus and a toxic effect against Vibrio fischeri cells (82.8% cell damage). High cholesterol-binding capacity and triglycerides-binding capacity (57.9% and 41.6% after 24 h of incubation with the tested substances, resp.) were also detected for the investigated samples of GpEPS.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Osińska-Jaroszuk M,Jaszek M,Mizerska-Dudka M,Błachowicz A,Rejczak TP,Janusz G,Wydrych J,Polak J,Jarosz-Wilkołazka A,Kandefer-Szerszeń Mdoi
10.1155/2014/743812subject
Has Abstractpub_date
2014-01-01 00:00:00pages
743812eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
杂志文章abstract:OBJECT:The aim of this report was to explore the clinical presentation, radiological features, treatment methods, and outcome of micro-AVMs presenting with intracerebral hemorrhage. METHODS:The clinical data, radiological features, treatment, and follow-up results for a consecutive series of 13 cases with micro-AVMs w...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/257153
更新日期:2015-01-01 00:00:00
abstract::There were no systematic researches about autophagy-related long noncoding RNA (lncRNA) signatures to predict the survival of patients with colon adenocarcinoma. It was necessary to set up corresponding autophagy-related lncRNA signatures. The expression profiles of lncRNAs which contained 480 colon adenocarcinoma sam...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9807918
更新日期:2020-09-02 00:00:00
abstract::Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with t...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2017/4359424
更新日期:2017-01-01 00:00:00
abstract:Background:As a newly discovered lncRNA, bladder cancer-associated transcript 1 (BLACAT1) has been reported to correlate with poor clinical outcomes in several different cancers. This study aimed to evaluate its generalized predictive value for cancer prognosis. Materials and Methods:We thoroughly searched PubMed, Emb...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/1275491
更新日期:2019-04-02 00:00:00
abstract:BACKGROUND:This retrospective study was designed to investigate the efficacy and safety of intermittent portal triad clamping (PTC) with low central venous pressure (CVP) in liver resections. METHODS:Between January 2007 and August 2013, 115 patients underwent liver resection with intermittent PTC. The patients' data ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/297971
更新日期:2013-01-01 00:00:00
abstract::Objective. To evaluate the efficacy of bundle intervention on healthcare-associated (HA) methicillin-resistant Staphylococcus Aureus (MRSA) infection in the neonatal intensive care unit (NICU). Methods. In this study, 11,277 infants having undergone treatment at the NICU in Xiamen, China, from January 2014 to February...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5490413
更新日期:2019-07-10 00:00:00
abstract::Robot-Assisted Rehabilitation (RAR) is relevant for treating patients affected by nervous system injuries (e.g., stroke and spinal cord injury). The accurate estimation of the joint angles of the patient limbs in RAR is critical to assess the patient improvement. The economical prevalent method to estimate the patient...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/2581924
更新日期:2016-01-01 00:00:00
abstract::The aim of this study was to develop a freeze-drying protocol facilitating successful processing of plant material containing the small surface antigen of hepatitis B virus (S-HBsAg) while preserving its VLP structure and immunogenicity. Freeze-drying of the antigen in lettuce leaf tissue, without any isolation or pur...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/485689
更新日期:2014-01-01 00:00:00
abstract::The polarization of macrophages and its anti-inflammatory and proinflammatory properties play a significant role in host response after implant placement to determine the outcome of osseointegration and long-term survival. In the previous study, we immobilized an antimicrobial peptide, GL13K, onto titanium surfaces to...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/2327034
更新日期:2020-07-24 00:00:00
abstract::Hypolactasia, or intestinal lactase deficiency, affects more than half of the world population. Currently, xylose quantification in urine after gaxilose oral administration for the noninvasive diagnosis of hypolactasia is performed with the hand-operated nonautomatable phloroglucinol reaction. This work demonstrates t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/8421418
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/701682
更新日期:2014-01-01 00:00:00
abstract:Objective of Study:To investigate, using the FEM, the influence of different notching angles on a zirconium dioxide coping with the aim of establishing the optimal connection conditions with veneering ceramic. Materials and Methods:To calculate the stresses in the connection between zirconia coping and veneering ceram...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/7485409
更新日期:2019-07-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8052013
更新日期:2020-05-14 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/154549
更新日期:2013-01-01 00:00:00
abstract::Cancer is known to have unique metabolic features such as Warburg effect. Current cancer therapy has moved forward from cytotoxic treatment to personalized, targeted therapies, with some that could lead to specific metabolic changes, potentially monitored by imaging methods. In this paper we addressed the important as...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/625095
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2018/3476425
更新日期:2018-12-09 00:00:00
abstract::Vitamin B6 is one of the most versatile cofactors in plants and an essential phytonutrient in the human diet that benefits a variety of human health aspects. Although biosynthesis of the vitamin has been well resolved in recent years, the main research is currently based on Arabidopsis thaliana with very little work d...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/389723
更新日期:2013-01-01 00:00:00
abstract::Seed inoculation with bacterial consortium was found to increase legume yield, providing a higher growth than the standard nitrogen treatment methods. Alfalfa plants were inoculated by mono- and binary compositions of nitrogen-fixing microorganisms. Their physiological and biochemical properties were estimated. Inocul...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/202597
更新日期:2015-01-01 00:00:00
abstract:Objective:To compare the effectiveness of arthroscopic partial meniscectomy (APM) and physical therapy (PT) for degenerative meniscus tears. Method:We conducted a literature search through PubMed, Embase, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov. Randomized controlled trials in adults...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2020/1709415
更新日期:2020-03-03 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/478248
更新日期:2014-01-01 00:00:00
abstract::Targeting nanoparticles by conjugating various specific ligands has shown potential therapeutic efficacy in nanomedicine. However, poor penetration of antitumor drugs into solid tumors remains a major obstacle. Here, we describe a targeting strategy for antitumor drug delivery by conjugating a crosslinked multilamella...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/378380
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1578643
更新日期:2018-08-13 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/764382
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5923025
更新日期:2020-10-23 00:00:00
abstract::Toxoplasma gondii infects all warm-blooded animals, including humans, causing serious public health problems and great economic loss for the food industry. Commonly used serological tests require costly and hazardous preparation of whole Toxoplasma lysate antigens from tachyzoites. Here, we have evaluated an alternati...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/690529
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/2174824
更新日期:2018-11-05 00:00:00
abstract:UNLABELLED:Ehlers-Danlos syndrome hypermobility type a. k. a. joint hypermobility syndrome (JHS/EDS-HT) is a hereditary musculoskeletal disorder associating generalized joint hypermobility with chronic pain. Anecdotal reports suggest a prominent role for kinesiophobia in disease manifestations, but no study has systema...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/580460
更新日期:2013-01-01 00:00:00
abstract::Abnormal expression of neuroepithelial cell transforming gene 1 (NET1) has been authenticated in many human cancers, including lung cancer. We have previously reported that NET1 functioned as an oncogene and promoted human non-small-cell lung cancer (NSCLC) growth and migration. However, the correlation between NET1 a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/1648419
更新日期:2020-01-11 00:00:00
abstract::Severe stages of acute, colonic diverticulitis can progress into intestinal perforations with peritonitis. In such cases, urgent treatment is needed, and Hartmann's procedure is the standard treatment for cases with fecal peritonitis. Peritoneal lavage may be an alternative to resection for acute diverticulitis with p...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/380607
更新日期:2014-01-01 00:00:00
abstract::Revealing the gene regulation networks governing cancer initiation and development is necessary while it remains uncompleted. In recent years, enhancers have been reported to be widely transcribed, resulting in the generation of enhancer RNAs (eRNAs). Previous studies have reported that eRNAs are a subclass of long no...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/2405351
更新日期:2018-05-22 00:00:00