Antiangiogenic effect of itraconazole on corneal neovascularization: a pilot experimental investigation.

abstract：:Cataractous lens images taken with different camera types for retroillumination photography were compared. Images taken by conventional photo slitlamp and fundus cameras were not suitable for image analysis. Retroillumination photography with a conventional fundus camera with additional polarizing filters seemed to be...

journal_title：Ophthalmic research

authors： Sakamoto Y,Rankov G,Sasaki K

更新日期：1990-01-01 00:00:00

abstract：:Energy-dispersive X-ray analysis was used to obtain distribution profiles of Na, K, Cl, P and S in rapidly frozen-dried bulk specimens, and in cryosections of the normal rat lens. Na and Cl are highly concentrated in the capsule, and K and P, in the epithelial cells. Profiles of the entire radius of a lens show relati...

journal_title：Ophthalmic research

authors： Harding CV,Susan S,Bobrowski W

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:The lens is the ocular structure most susceptible to oxidative damage. Antioxidants, micronutrients and phytochemicals have been extensively studied for their possible effects to prevent or delay the progression of various eye diseases. OBJECTIVES:A brief overview of the updated literature on the role of an...

journal_title：Ophthalmic research

authors： Agte V,Tarwadi K

更新日期：2010-01-01 00:00:00

abstract：:To study the mode of riboflavin metabolism in the lens in vivo, the uptake of 14C-labeled riboflavin and synthesis of ester forms from 14C-riboflavin were assayed in the single whole lens of the rats. 14C-riboflavin uptake increased in proportion to the substrate concentration in the incubation medium, reaching a plat...

journal_title：Ophthalmic research

authors： Ono S,Hirano H

更新日期：1983-01-01 00:00:00

abstract：PURPOSE:To study the ability to appreciate qualitative features that indicate disease activity in patients with neovascular age-related macular degeneration (AMD) and to analyze the differences in automated retinal thickness measurement, using 1 time domain optical coherence tomography (TD-OCT) and 2 different spectral...

journal_title：Ophthalmic research

authors： Querques G,Forte R,Berboucha E,Martinelli D,Coscas G,Soubrane G,Souied EH

更新日期：2011-01-01 00:00:00

abstract：:This study developed a modified monolayer culture technique for expansion of retinal progenitor cells in vitro. Using this method, spheres collected by low centrifugation from free floating cultures were re-seeded onto poly-D-lysine pre-coated flasks, and cultured in the retinal progenitor cells medium (including fibr...

journal_title：Ophthalmic research

authors： Lai P,Tang S,Yi J,Zhu X,Zou Y,Xie H,Gao Y,Lin S

更新日期：2008-10-01 00:00:00

abstract：:The purpose of this study was to compare the variability of the amplitude ratios and latencies of the electro-oculogram (EOG) light peak (LP) in three different recording conditions: Arden ratio (dark trough (DT): 12 min), modified Arden ratio (DT: 15 min) and light peak/dark baseline ratio (LP/BL: 35 min of dark adap...

journal_title：Ophthalmic research

authors： Lessel MR,Thaler A,Scheiber V,Heilig P

更新日期：1993-01-01 00:00:00

abstract：:This study was undertaken to characterize the mechanism of ocular irritation to YAG laser capsulotomy in rabbits. The blocking agents were administered intravitreally. (D-Arg1,D-Pro2,D-Trp7,9)-SP, a substance P antagonist, tended to reduce miosis but had no effect on intraocular pressure (IOP). It had less effect on m...

journal_title：Ophthalmic research

authors： Oksala O,Stjernschantz J,von Dickhoff K

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of bilateral lateral rectus muscle recession (BLR) to treat recurrent exotropia after bilateral medial rectus muscle resection (BMR). METHODS:Twenty-four patients who underwent BLR for recurrent exotropia and were followed up for more than 6 months were included in this retrospective s...

journal_title：Ophthalmic research

authors： Wang X,Chen X,Liu L

更新日期：2019-01-01 00:00:00

abstract：:Vitamin E (d-alpha-tocopherol) and aspirin were evaluated for their effects on the phase separation temperature, Tc, of calf lens cytoplasm. Vitamin E and aspirin were added to nuclear homogenate and the change in Tc was measured. Aspirin had no measurable effect on Tc. Vitamin E lowered Tc at a rate of -22 degrees C ...

journal_title：Ophthalmic research

authors： Eccarius S,Clark JI

更新日期：1987-01-01 00:00:00

abstract：:Metabolic changes in the rabbit lens have been studied by means of nuclear magnetic resonance spectroscopy. These changes have been induced by prolonged topical treatment with dexamethasone. Our results demonstrate an increase in sorbitol, sorbitol-3-phosphate, fructose-3-phosphate, glycerol-3-phosphate and glucose-6-...

journal_title：Ophthalmic research

authors： Pescosolido N,Miccheli A,Manetti C,Iannetti GD,Feher J,Cavallotti C

更新日期：2001-03-01 00:00:00

abstract：:The tear levels of cholesterol of 17 patients with chronic blepharitis and 17 healthy subjects were determined by the photometric method. The mean cholesterol level of the patients was determined to be 56.1 +/- 8.9 (SEM) mg/dl. No statistically significant difference between the tear cholesterol levels of the two grou...

journal_title：Ophthalmic research

authors： Saatçi AO,Irkeç M,Unlü N

更新日期：1990-01-01 00:00:00

abstract：:The vibrating probe detects and measures currents around cells and organs. With its use, it is possible to demonstrate strong outward potassium currents at the equator of the lens and strong inward sodium currents at the optical poles. The addition of microelectrodes to the system permits one to define the nature of t...

journal_title：Ophthalmic research

authors： Patterson JW

更新日期：1988-01-01 00:00:00

abstract：:The activities of sialyl-, fucosyl- and galactosyltransferase were measured in membrane preparations from bovine eyes. Radioactive sugars from CMP-N-neuraminic acid, GDP-fucose and UDP-galactose were incorporated into the endogenous and exogenous acceptors. The enzymatic activities of all three glycosyltransferases we...

journal_title：Ophthalmic research

authors： Unoki K,Uehara F,Muramatsu T

更新日期：1990-01-01 00:00:00

abstract：:We examined 304 conjunctiva in 152 subjects by clinical, cytologic, and bacteriologic methods. Bacteriologic samples were evaluated after a 48-hour incubation. Bacterial growth was found in 8 (20.5%) of 39 patients with clinically normal conjunctiva and no polymorphonuclear leukocytes (PMNs), and in 8 (61.5%) of 13 su...

journal_title：Ophthalmic research

authors： Ugomori S,Hayasaka S,Setogawa T

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To describe the characteristics of macular lesions after eye trauma using spectral-domain optical coherence tomography (OCT). METHODS:We retrospectively reviewed and described 2-dimensional (2D) and 3-dimensional (3D) spectral-domain OCT characteristics of 24 consecutive eyes of 24 cases that were identified w...

journal_title：Ophthalmic research

authors： Yu W,Zheng L,Zhang Z,Dai R,Dong F

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To compare tear film osmolarity (TFO) between patients with diabetes mellitus (DM) and normal healthy individuals. METHODS:In this prospective case-controlled study, the TFO in 46 normal subjects (control group) and 55 patients with DM (study group) was evaluated. TFO in milliosmole (mOsm) was measured by usin...

journal_title：Ophthalmic research

authors： Sağdık HM,Ugurbas SH,Can M,Tetikoğlu M,Ugurbas E,Uğurbaş SC,Alpay A,Uçar F

更新日期：2013-01-01 00:00:00

abstract：:During the process of terminal differentiation, the fibre cells in the eye lens undergo many changes that are reminiscent of apoptotic/necrotic changes. Mitochondria, for instance, undergo permeability transition and nuclear degradation is accompanied by chromatin condensation, disintegration of the nucleolus, dissolu...

journal_title：Ophthalmic research

authors： Dahm R

更新日期：1999-01-01 00:00:00

abstract：:The crystalline lens capsules of eye bank eyes, intraocular lens (IOL)-inserted eyes and those of monkey and rabbit eyes were observed in vivo and/or in vitro through a specular microscope or Scheimpflug slit images in combination with new image-processing techniques and scanning electron microscopy. Shagreen patterns...

journal_title：Ophthalmic research

authors： Sasaki K,Kojima M,Hara T

更新日期：1988-01-01 00:00:00

abstract：:Dragomirescu et al. [1983] described a 2-chamber flow system for the incubation of lenses with an inserted photometer to measure changes in lens transparency. Mester et al. [1984] applied the method to simulate conditions occurring during vitrectomy, which occasionally leads to reversible lens opacification. Using Sch...

journal_title：Ophthalmic research

authors： Hockwin O,Dragomirescu V,Schwarz B

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To establish a retinal blood flow database in normal human eyes using the Canon Laser Blood Flowmeter (CLBF). METHOD:Fourteen healthy subjects (7 males, 7 females) between the ages of 24 and 33 underwent birectional laser Doppler velocimetry (BLDV) in one eye using the CLBF. Measurements consisting of blood ve...

journal_title：Ophthalmic research

authors： Garcia JP Jr,Garcia PT,Rosen RB

更新日期：2002-09-01 00:00:00

abstract：:Animal models are indispensable for pharmaceutical investigations. However, investigators often have difficulty choosing the appropriate modal for their research. To provide a comprehensive and convenient source of information about animal models of proliferative vitreoretinopathy (PVR), the current review sorted and ...

journal_title：Ophthalmic research

authors： Hou H,Nudleman E,Weinreb RN

更新日期：2018-01-01 00:00:00

abstract：AIM:This study was done to evaluate the role of pentosidine in predicting the progression of diabetic retinopathy. PATIENTS AND METHODS:We included 30 subjects with insulin-dependent diabetes mellitus (type 1) and 10 healthy control individuals. A case control study was done. Full ophthalmological examination together...

journal_title：Ophthalmic research

authors： Salman AG,Mansour DE,Swelem AH,Al-Zawahary WM,Radwan AA

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the characteristics of corneal endothelial cells and central corneal thickness (CCT) in patients with diabetes mellitus (DM), comparing them with those of healthy subjects (controls) and to determine potential factors affecting the corneal parameters in patients with DM. M...

journal_title：Ophthalmic research

authors： Papadakou P,Chatziralli I,Papathanassiou M,Lambadiari V,Siganos CS,Theodossiadis P,Kozobolis V

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Genipin (GP) is a safe method for corneal crosslinking, even for very thin corneas. However, there have been no reports on the optimal GP concentration range to use in vivo for corneal crosslinking. OBJECTIVES:To investigate the safety of corneal crosslinking after a 24-h incubation with different concentra...

journal_title：Ophthalmic research

authors： Song W,Tang Y,Qiao J,Li H,Rong B,Yang S,Wu Y,Yan X

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To investigate the effect of propolis, a natural resin produced by honeybees, in the treatment of alkali-injured rabbit eyes. METHOD:A corneal alkali burn was induced by applying filter paper immersed in 1 N NaOH on the central axis of the right corneas of 24 rabbits for 30 s. The animals were divided into thr...

journal_title：Ophthalmic research

authors： Oztürk F,Kurt E,Cerçi M,Emiroglu L,Inan U,Türker M,Ilker S

更新日期：2000-01-01 00:00:00

abstract：AIMS:Staphylococcus epidermidis is considered a commensal bacterium; however, it is frequently isolated from ocular infections showing a multidrug resistance. Ciprofloxacin-resistant strains have been isolated from ocular infections; however, resistance to quinolone, such as gatifloxacin and moxifloxacin, is not often ...

journal_title：Ophthalmic research

authors： Betanzos-Cabrera G,Juárez-Verdayes MA,González-González G,Cancino-Díaz ME,Cancino-Díaz JC

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To compare the effects between intravitreal and periocular injections of adenoviral vectored pigment epithelium-derived factor (AdPEDF) on suppressing established choroidal neovascularization (CNV) in rats. METHODS:Sixty-eight female BN rats (136 eyes) aged 6-8 weeks were involved in this study. The CNV animal...

journal_title：Ophthalmic research

authors： Yan H,Cui J,Wang Y,Yu Y

更新日期：2013-01-01 00:00:00

abstract：:The turnover and migration of synthesized glycoproteins in the cultured retinal pigment epithelium have been studied. Quantitative study indicated that half-time of 3H-fucosylglycoproteins was 11.6 days. Autoradiography was performed several times after incubation of 3H-fucose. Retinal pigment epithelium constantly sy...

journal_title：Ophthalmic research

authors： Entani S,Yoshimura N,Chihara E,Tsukahara I

更新日期：1986-01-01 00:00:00

abstract：:Two out of three normal eyes tested with frequent instillation of 30 microliters of drops of 0.5% bupranolol, a beta 1 + beta 2 blocking drug with some intrinsic sympathomimetic and local anesthetic activity, showed a miotic effect of the order of a 25% reduction of pupil area, as estimated by an open-loop iris-videor...

journal_title：Ophthalmic research

authors： Tsukahara S,Sasaki T,Yamabayashi S,Shimizu Y

更新日期：1986-01-01 00:00:00