Tear film osmolarity in patients with diabetes mellitus.

abstract：:Cataract is the leading cause of blindness worldwide. It is a multifactorial disease primarily associated with oxidative stress produced by free radicals. The protection offered by various antioxidants in cataract development is well established. Polyphenolic compounds present in green tea (Camellia sinensis) are repo...

journal_title：Ophthalmic research

authors： Gupta SK,Halder N,Srivastava S,Trivedi D,Joshi S,Varma SD

更新日期：2002-07-01 00:00:00

abstract：:Dragomirescu et al. [1983] described a 2-chamber flow system for the incubation of lenses with an inserted photometer to measure changes in lens transparency. Mester et al. [1984] applied the method to simulate conditions occurring during vitrectomy, which occasionally leads to reversible lens opacification. Using Sch...

journal_title：Ophthalmic research

authors： Hockwin O,Dragomirescu V,Schwarz B

更新日期：1985-01-01 00:00:00

abstract：:Metabolic changes in the rabbit lens have been studied by means of nuclear magnetic resonance spectroscopy. These changes have been induced by prolonged topical treatment with dexamethasone. Our results demonstrate an increase in sorbitol, sorbitol-3-phosphate, fructose-3-phosphate, glycerol-3-phosphate and glucose-6-...

journal_title：Ophthalmic research

authors： Pescosolido N,Miccheli A,Manetti C,Iannetti GD,Feher J,Cavallotti C

更新日期：2001-03-01 00:00:00

abstract：:The possible multiple effect of galactose diet and X-irradiation on cataract development in mice was investigated by scanning electron microscopy. X-ray cataracts were induced by maintaining animals either on a normal or 50% galactose diet. No detectable changes in lens morphology were seen in animals fed galactose al...

journal_title：Ophthalmic research

authors： Kodama T,Reddy VN,Giblin F,Kinoshita JH,Harding C

更新日期：1983-01-01 00:00:00

abstract：:To evaluate the possible role of nitric oxide in the pathogenesis of exogenous prostaglandin (PG) induced aqueous flare elevation, we examined the effect of NG-nitro-L-arginine methyl ester (L-NAME), an L-arginine analogue acting as a specific inhibitor of nitric oxide synthase, on the elevation of aqueous flare in pi...

journal_title：Ophthalmic research

authors： Hiraki S,Zhang XY,Hayasaka S

更新日期：1996-01-01 00:00:00

abstract：:The tear levels of cholesterol of 17 patients with chronic blepharitis and 17 healthy subjects were determined by the photometric method. The mean cholesterol level of the patients was determined to be 56.1 +/- 8.9 (SEM) mg/dl. No statistically significant difference between the tear cholesterol levels of the two grou...

journal_title：Ophthalmic research

authors： Saatçi AO,Irkeç M,Unlü N

更新日期：1990-01-01 00:00:00

abstract：:The vibrating probe detects and measures currents around cells and organs. With its use, it is possible to demonstrate strong outward potassium currents at the equator of the lens and strong inward sodium currents at the optical poles. The addition of microelectrodes to the system permits one to define the nature of t...

journal_title：Ophthalmic research

authors： Patterson JW

更新日期：1988-01-01 00:00:00

abstract：AIMS:Staphylococcus epidermidis is considered a commensal bacterium; however, it is frequently isolated from ocular infections showing a multidrug resistance. Ciprofloxacin-resistant strains have been isolated from ocular infections; however, resistance to quinolone, such as gatifloxacin and moxifloxacin, is not often ...

journal_title：Ophthalmic research

authors： Betanzos-Cabrera G,Juárez-Verdayes MA,González-González G,Cancino-Díaz ME,Cancino-Díaz JC

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To evaluate the long-term outcome of trabeculectomy with intra- and postoperative 5-fluorouracil (5-FU) application in glaucoma. METHODS:Eighty-six patients with glaucoma planned for primary trabeculectomy with 5-FU and a minimum follow-up of 3 years were retrospectively analyzed. Success rates, postsurgical 5...

journal_title：Ophthalmic research

authors： Lindemann F,Plange N,Kuerten D,Schimitzek H,Koutsonas A

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To evaluate a technique of autologous internal limiting membrane (ILM) fragment transplantation for the treatment of large, chronic, and/or refractory macular holes (MH). DESIGN:This was a 6-month prospective interventional case series. METHOD:Ten eyes of 10 patients with MH underwent pars plana vitretomy (...

journal_title：Ophthalmic research

authors： De Novelli FJ,Preti RC,Ribeiro Monteiro ML,Pelayes DE,Junqueira Nóbrega M,Takahashi WY

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To assess changes of tear film function in patients with pterygium after pterygium excision combined with limbal-conjunctival autograft transplantation. METHODS:Sixty eyes of 60 patients were entered in the study. The Schirmer test, tear breakup time (BUT) and mucus fern test (MFT) were evaluated in the pati...

journal_title：Ophthalmic research

authors： Wang S,Jiang B,Gu Y

更新日期：2011-01-01 00:00:00

abstract：:The activities of sialyl-, fucosyl- and galactosyltransferase were measured in membrane preparations from bovine eyes. Radioactive sugars from CMP-N-neuraminic acid, GDP-fucose and UDP-galactose were incorporated into the endogenous and exogenous acceptors. The enzymatic activities of all three glycosyltransferases we...

journal_title：Ophthalmic research

authors： Unoki K,Uehara F,Muramatsu T

更新日期：1990-01-01 00:00:00

abstract：:Calf water-soluble (WS) crystallins consist of high-molecular weight (HM), alpha-, beta H-, beta L-, beta s- and gamma-crystallins. alpha-Crystallin as a molecular chaperone forms a structure with a central hole, known as Carver's model. The only crystallins fitting into this central cavity are beta s- and gamma-cryst...

journal_title：Ophthalmic research

authors： Bours J

更新日期：1996-01-01 00:00:00

abstract：:Diabetic macular edema is a common condition frequently encountered by ophthalmologists. In this piece we briefly review its definition, pathogenesis, clinical aspects, imaging, and treatment. ...

journal_title：Ophthalmic research

authors： Moisseiev E,Loewenstein A

更新日期：2017-01-01 00:00:00

abstract：:This study examined and characterized the distribution and kinetics of the inflammatory cell response to pseudomonas ocular challenge in susceptible C57BL/6J and resistant DBA/2J mice. Initially, in the cornea, the number of neutrophilic leukocytes (PMNs), macrophages/monocytes or lymphocytes was 2-2.5 times greater i...

journal_title：Ophthalmic research

authors： Hazlett LD,Zucker M,Berk RS

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:Osthole is an agent isolated from Cnidium monnieri (L.) Cusson and has been used to treat several disorders. Corneal neovascularization is a sight-threatening condition associated with several inflammatory or infectious ocular disorders. In this study, we investigated the anti-angiogenic effects of osthole on c...

journal_title：Ophthalmic research

authors： Zhang QY,Tao SY,Lu C,Li JJ,Li XM,Jiang Q,Yan B

更新日期：2020-01-01 00:00:00

abstract：:HY-1 genotype chick lenses display epithelial hyperplasia and associated lens opacities. Membrane proteins from HY-1 and normal chick lenses were separated by isoelectric focusing, and 45Ca2+ binding capacities were determined. Markedly higher (congruent to 900-fold) binding of 45Ca2+ was observed in high molecular we...

journal_title：Ophthalmic research

authors： Odeigah PG,Patmore L

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To evaluate the role of initial visual acuity (VA) as a potential prognostic factor for final VA in patients with branch retinal vein occlusion (BRVO). METHODS:A retrospective data analysis involving 163 patients with macular edema secondary to BRVO treated according to the recommendations of the Branch Vein O...

journal_title：Ophthalmic research

authors： Rehak J,Dusek L,Chrapek O,Fric E,Rehak M

更新日期：2011-01-01 00:00:00

abstract：AIMS:The purpose of this paper was to determine the lacrimal concentration of IL-1α and MMP-9 in patients with active ocular rosacea before and after systemic treatment with azithromycin or doxycycline. METHODS:After 4 weeks of therapy with azithromycin (500 mg/day, 3 days a week PO) or doxycycline (200 mg/day PO), la...

journal_title：Ophthalmic research

authors： Lam-Franco L,Perfecto-Avalos Y,Patiño-Ramírez BE,Rodríguez García A

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To investigate the effect of vitreomacular adhesion (VMA) on the outcome of antiangiogenic treatment for neovascular age-related macular degeneration (AMD). METHODS:Ninety-nine eyes of 83 patients were used in our cohort study. We prospectively evaluated best corrected visual acuity (BCVA) and central retinal ...

journal_title：Ophthalmic research

authors： Kanadani TCM,Dos Reis Veloso CE,Dorairaj S,Nehemy MB

更新日期：2017-01-01 00:00:00

abstract：:Indirect measurement in vivo of nuclear color of 64 cataractous eyes was made using a method of image analysis of photographed lenses developed by the authors. The grade of yellow of lens color was characterized by its dominant wavelength and excitation purity in the CIE chromaticity diagram. The differences were smal...

journal_title：Ophthalmic research

authors： Sasaki K,Hiiragi M,Sakamoto Y,Shibata T

更新日期：1985-01-01 00:00:00

abstract：:Lenticular S-adenosylmethionine synthetase has been partially purified and characterized. Lower levels of S-adenosylmethionine synthetase were detected by a sensitive radioactive assay procedure in the lenticular extract obtained from the pooled lenses of alloxan-treated rats 96 days of age as compared to the nontreat...

journal_title：Ophthalmic research

authors： Ahmad SS,Ahmad SI,Rahman MA

更新日期：1982-01-01 00:00:00

abstract：:The crystalline lens capsules of eye bank eyes, intraocular lens (IOL)-inserted eyes and those of monkey and rabbit eyes were observed in vivo and/or in vitro through a specular microscope or Scheimpflug slit images in combination with new image-processing techniques and scanning electron microscopy. Shagreen patterns...

journal_title：Ophthalmic research

authors： Sasaki K,Kojima M,Hara T

更新日期：1988-01-01 00:00:00

abstract：:Previous research from this laboratory showed that human lacrimal fluid peroxidase has cyclic variations during the menstrual cycle, correlated with plasma levels of 17beta-oestradiol. In the present investigation, variations of enzyme activity and total protein content during the oestrous cycle of young adult female ...

journal_title：Ophthalmic research

authors： Madia F,Liberati V,de Feo G,Marcozzi G

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:To describe the characteristics of macular lesions after eye trauma using spectral-domain optical coherence tomography (OCT). METHODS:We retrospectively reviewed and described 2-dimensional (2D) and 3-dimensional (3D) spectral-domain OCT characteristics of 24 consecutive eyes of 24 cases that were identified w...

journal_title：Ophthalmic research

authors： Yu W,Zheng L,Zhang Z,Dai R,Dong F

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To analyze chloroquine-induced morphological changes in the retinal pigment epithelium (RPE) and Bruch's membrane (BM). METHODS:Retina-choroid complexes of chloroquine-treated Long-Evans rats were analyzed by electron microscopy. RESULTS:Intercellular spaces between the RPE cells and BM were enlarged. Residua...

journal_title：Ophthalmic research

authors： Peters S,Reinthal E,Blitgen-Heinecke P,Bartz-Schmidt KU,Schraermeyer U

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To investigate therapeutic ocular surface medium (TOSM), a potential physiological tear replacement therapy, for persistent epithelial defect (PED). METHODS:11 eyes of 10 patients with PED for ≥ 2 weeks without improvement despite conventional treatment were enrolled in a prospective pilot study of TOSM over 1...

journal_title：Ophthalmic research

authors： Watson SL,Geerling G,Dart JK

更新日期：2014-01-01 00:00:00

abstract：:Age-related lens opacity is the major cause of loss of vision affecting more than half of the world's blind. The development of cataract is associated with changes in the structure of the lens. The lens consists largely of closely packed fibre cells forming a transparent syncytium. The main intrinsic polypeptide (MIP)...

journal_title：Ophthalmic research

authors： Lea EJ

更新日期：1996-01-01 00:00:00

abstract：:To investigate the binding of peanut-agglutinin (PNA) on porcine corneal tissue, several methods of tissue processing were used. In cryostat sections of postmortem tissue, PNA labeling of epithelial cell membranes was detected. In the stroma, a fibrillar structure parallel to the corneal surface was found. The anterio...

journal_title：Ophthalmic research

authors： Vogelberg K,Böhnke M,von Domarus D

更新日期：1988-01-01 00:00:00

abstract：:The pathology of rainbow trout lenses incubated in various media and at various temperatures was examined by electron microscopy. After incubation at 0 degrees C for 5 h, no changes were observed in transparency and cytology. Irreversible warm cataract occurred at 37 degrees C, which corresponds to the body temperatur...

journal_title：Ophthalmic research

authors： Uga S,Ishikawa S,Hikida M,Iwata S

更新日期：1986-01-01 00:00:00