Abstract:
:To investigate the binding of peanut-agglutinin (PNA) on porcine corneal tissue, several methods of tissue processing were used. In cryostat sections of postmortem tissue, PNA labeling of epithelial cell membranes was detected. In the stroma, a fibrillar structure parallel to the corneal surface was found. The anterior part of Descemet's membrane was strongly positive, whereas the posterior Descemet membrane was negative. The endothelium was faintly positive. After 3 days of organ culture, the epithelial and endothelial staining patterns were not significantly changed. The stromal fibrils detected by PNA staining showed a considerable spatial disarrangement due to the stromal hydration.
journal_name
Ophthalmic Resjournal_title
Ophthalmic researchauthors
Vogelberg K,Böhnke M,von Domarus Ddoi
10.1159/000266748subject
Has Abstractpub_date
1988-01-01 00:00:00pages
337-42issue
6eissn
0030-3747issn
1423-0259journal_volume
20pub_type
杂志文章abstract:AIM:Ultraviolet (UV) B irradiation induces gene expression that leads to skin cancer. Among the transcription factors induced by UVB radiation exposure, the cyclic AMP response element-binding protein (CREB) is significant. Since several factors downstream of CREB signaling are known to be involved in pterygium pathoge...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000347124
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:The aim of the present study was to characterize the development of after-cataract in the rabbit by measuring its wet weight, protein, DNA and glycosaminoglycan (GAG) contents and using Scheimpflug and slitlamp analysis. Further, aqueous humor (AqH) leukocytes, protein and lens epithelial cell proliferation act...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000048320
更新日期:2002-01-01 00:00:00
abstract::The refractive indices in various rat retinal layers, based on the total dry mass concentration, ranged from 1.369 to 1.385. The ratios of the refractive indices of neighboring retinal layers were near unity. This finding suggests that light passes through the rat retina without much refraction. ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267223
更新日期:1993-01-01 00:00:00
abstract::Although it is essential that intraocular pressure (IOP) be reduced in glaucoma treatment, it is also vitally important to provide sufficient blood flow to eye tissues so that healthy visual field is maintained. It is possible for an agent to reduce IOP and blood supply to the eye. In that case, glaucoma appears to be...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265445
更新日期:1986-01-01 00:00:00
abstract::The main objective of this study was to determine the intraocular concentration of fluorescein after applying five eye drops with only 1-min intervals in human eyes. The concentration of fluorescein in corea and aqueous was studied with fluorophotometry in 11 healthy volunteers. Five 10-microliter drops of 2% fluoresc...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267997
更新日期:1997-01-01 00:00:00
abstract::To evaluate the possible role of nitric oxide in the pathogenesis of exogenous prostaglandin (PG) induced aqueous flare elevation, we examined the effect of NG-nitro-L-arginine methyl ester (L-NAME), an L-arginine analogue acting as a specific inhibitor of nitric oxide synthase, on the elevation of aqueous flare in pi...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267912
更新日期:1996-01-01 00:00:00
abstract::In a search for a pharmacologic adjuvant in the management of posttraumatic proliferative vitreoretinopathy (PVR), we investigated the effect of intravitreal injection of prinomastat (AG3340) on an experimental model. Posterior penetrating eye trauma was created in one eye each of 24 New Zealand white rabbits. One wee...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000055636
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of bilateral lateral rectus muscle recession (BLR) to treat recurrent exotropia after bilateral medial rectus muscle resection (BMR). METHODS:Twenty-four patients who underwent BLR for recurrent exotropia and were followed up for more than 6 months were included in this retrospective s...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000494560
更新日期:2019-01-01 00:00:00
abstract::Indirect measurement in vivo of nuclear color of 64 cataractous eyes was made using a method of image analysis of photographed lenses developed by the authors. The grade of yellow of lens color was characterized by its dominant wavelength and excitation purity in the CIE chromaticity diagram. The differences were smal...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265345
更新日期:1985-01-01 00:00:00
abstract::Cellular events in the rat conjunctiva were studied at 1, 6 and 24 h following the topical application of leukotriene B4. A significant increase was noted in the number of eosinophils (p less than 0.01) and neutrophils (p less than 0.05) at 1 h and only in eosinophils at 6 h after leukotriene B4 application at the 2-m...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000266873
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To assess changes of tear film function in patients with pterygium after pterygium excision combined with limbal-conjunctival autograft transplantation. METHODS:Sixty eyes of 60 patients were entered in the study. The Schirmer test, tear breakup time (BUT) and mucus fern test (MFT) were evaluated in the pati...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000321531
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:Extensive clinical investigations of the biocompatibility of different intraocular lenses (IOLs) have been made in an effort to optimize the outcome of modern cataract surgery. The aim of this study was to add animal eye experimental implantation data regarding cellular reaction on the anterior surface of IOLs....
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000087100
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:The aim of this work was to compare the efficacy of intravitreal dexamethasone implant (Ozurdex) and intravitreal ranibizumab (Lucentis) in the treatment of macular edema (ME) caused by retinal vein occlusion (RVO). METHODS:Thirty-two ME cases treated with Ozurdex and 32 ME cases treated with ranibizumab we...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000458534
更新日期:2017-01-01 00:00:00
abstract::Cataract is the leading cause of blindness worldwide. It is a multifactorial disease primarily associated with oxidative stress produced by free radicals. The protection offered by various antioxidants in cataract development is well established. Polyphenolic compounds present in green tea (Camellia sinensis) are repo...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000063881
更新日期:2002-07-01 00:00:00
abstract::The presence of chondroitin- and heparan sulfate-containing proteoglycans and type IV collagen was searched for in human cameral mucous gel (CMG). Monoclonal antibodies specific for human heparan sulfate, chondroitin sulfate and collagen IV were used in ultrathin sections of Lowicryl-embedded human CMG. Only chondroit...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267569
更新日期:1995-01-01 00:00:00
abstract::The component oxygen fluxes that constitute a single recording of corneal oxygen uptake when a polarographic oxygen sensor (POS) is placed in contact with the cornea were determined in the in vivo rabbit eye by removing the epithelium and injecting an air bubble into the anterior chamber. The relative contribution of ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265369
更新日期:1985-01-01 00:00:00
abstract:AIMS:To evaluate the biologic effects of fluoroquinolone eye solutions without preservatives on cultured human corneal epithelial cells in vitro. METHODS:We studied the effect of diverse generations of topical fluoroquinolones such as ofloxacin 0.3%, levofloxacin 0.5%, tosufloxacin 0.3%, moxifloxacin 0.5% and gatiflox...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000357976
更新日期:2014-01-01 00:00:00
abstract::The high cytotoxicity of linoleic acid (LA) to cultured bovine lens epithelial cells is correlated with high uptake rates for the fatty acid (FA). Both, LA uptake and LA cytotoxicity strongly increase with the increasing LA-to-albumin molar ratio in the culture medium. Cellular uptake and cytotoxicity of LA can be com...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000055595
更新日期:2000-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the characteristics of corneal endothelial cells and central corneal thickness (CCT) in patients with diabetes mellitus (DM), comparing them with those of healthy subjects (controls) and to determine potential factors affecting the corneal parameters in patients with DM. M...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000507197
更新日期:2020-01-01 00:00:00
abstract::The ophthalmic examination of patients with hypertrophic cardiomyopathy treated with high doses of verapamil over a considerable period of time showed no evidence of a side effect of the drug, thus proving its ocular safety. This could be verified by densitometric image analysis of Scheimpflug photographs of the eyes....
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265327
更新日期:1984-01-01 00:00:00
abstract::Diabetic macular edema is a common condition frequently encountered by ophthalmologists. In this piece we briefly review its definition, pathogenesis, clinical aspects, imaging, and treatment. ...
journal_title:Ophthalmic research
pub_type: 杂志文章,评审
doi:10.1159/000458535
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Diabetic Retinopathy (DR) is one of the major vision-threatening causes worldwide. Searching for an individualized therapeutic strategy to prevent its progress is challenging. OBJECTIVE:This work aimed to investigate the association of angiogenesis-inducer vascular endothelial growth factor (VEGF) gene fa...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000511087
更新日期:2020-08-24 00:00:00
abstract::Cataractous lens images taken with different camera types for retroillumination photography were compared. Images taken by conventional photo slitlamp and fundus cameras were not suitable for image analysis. Retroillumination photography with a conventional fundus camera with additional polarizing filters seemed to be...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267063
更新日期:1990-01-01 00:00:00
abstract::Dry eye is the most prominent pathology among those involving the ocular surface: a decrease of the aqueous (less frequent) or the lipid (more frequent) component of the tear film is the cause of the diminished stability of tears that is observed in this pathology. Dry eye shows a clear distribution linked to both sex...
journal_title:Ophthalmic research
pub_type: 杂志文章,评审
doi:10.1159/000489093
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Amblyopia is an important public health problem and standard screening is quite necessary for early diagnosis and treatment especially for the remote areas. As the place of the largest Tibetan population, the Tibetan Plateau has special geographical characteristics such as high altitude, time zone, and eth...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000511264
更新日期:2020-12-04 00:00:00
abstract::The high-voltage electron microscope (HVEM) permits examination of sections much thicker (up to 1 micron) than those usually used in transmission electron microscopy, which are approximately 70 nm in thickness. Two examples of the utility of the HVEM in research on the ultrastructure of the retinal pigment epithelium ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265457
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:Abnormalities in electroretinograms (ERG), such as reduced amplitudes and delayed implicit times of a- and b-wave and oscillatory potentials (OPs), are one of the earliest features of diabetic retinopathy prior to obvious vascular changes in diabetic retinas. We have previously shown that serum levels of advanc...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000440768
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To describe the characteristics of macular lesions after eye trauma using spectral-domain optical coherence tomography (OCT). METHODS:We retrospectively reviewed and described 2-dimensional (2D) and 3-dimensional (3D) spectral-domain OCT characteristics of 24 consecutive eyes of 24 cases that were identified w...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000325732
更新日期:2012-01-01 00:00:00
abstract::The effect of large intake of dietary ascorbic acid on heat-induced eye lens protein damage has been studied. Male guinea pigs of the Hartley strain were used. Ascorbic acid was administered to the experimental animals in the drinking water. The mean daily ascorbic acid intakes for the control and experimental animals...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267008
更新日期:1990-01-01 00:00:00
abstract::The crystalline lens capsules of eye bank eyes, intraocular lens (IOL)-inserted eyes and those of monkey and rabbit eyes were observed in vivo and/or in vitro through a specular microscope or Scheimpflug slit images in combination with new image-processing techniques and scanning electron microscopy. Shagreen patterns...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000266575
更新日期:1988-01-01 00:00:00