Abstract:
:Indirect measurement in vivo of nuclear color of 64 cataractous eyes was made using a method of image analysis of photographed lenses developed by the authors. The grade of yellow of lens color was characterized by its dominant wavelength and excitation purity in the CIE chromaticity diagram. The differences were small between nuclear color observed from in vivo and in vitro photographs.
journal_name
Ophthalmic Resjournal_title
Ophthalmic researchauthors
Sasaki K,Hiiragi M,Sakamoto Y,Shibata Tdoi
10.1159/000265345subject
Has Abstractpub_date
1985-01-01 00:00:00pages
21-6issue
1eissn
0030-3747issn
1423-0259journal_volume
17pub_type
杂志文章abstract::The development and extension of fibrovascular or fibroglial membranes onto the retinal surface are a major cause of visual loss in diabetic patients with proliferative retinopathy and in patients suffering from retinal detachment with proliferative vitreoretinopathy. The pathogenesis of these proliferative diseases, ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267115
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To investigate the role of integrin-linked kinase (ILK) in endothelial cell migration, proliferation and tube formation in vitro. MATERIALS AND METHODS:Cultured RF/6A cells were knocked down for ILK using small interfering RNA (siRNA). Cellular ILK expression was quantified by real-time quantitative PCR and We...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000232971
更新日期:2009-01-01 00:00:00
abstract::Local pO2 was measured close to the ciliary process of the rabbit eye using polarographic microelectrodes under microendoscopic observation. The experiments were performed in 5 anaesthetized New Zealand rabbits. Changes in local pO2, intraocular pressure (IOP) and blood flow velocity (BFV) were investigated after intr...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267324
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Genipin (GP) is a safe method for corneal crosslinking, even for very thin corneas. However, there have been no reports on the optimal GP concentration range to use in vivo for corneal crosslinking. OBJECTIVES:To investigate the safety of corneal crosslinking after a 24-h incubation with different concentra...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000499571
更新日期:2019-01-01 00:00:00
abstract:AIM:To develop a local approach to study rabbit lacrimal secretion in situ by administering specific secretagogues directly onto the lacrimal gland (LG). METHODS:After the rabbit has been anesthetized, the inferior bulbar conjunctiva and underlying connective tissue are blunt dissected. A polyethylene tube, for drug d...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000111159
更新日期:2008-01-01 00:00:00
abstract::Diabetic macular edema is considered the most important factor related to visual impairment in patients with diabetic retinopathy. Together with the use of grid and focal laser photocoagulation, today the intravitreal administration of pharmacotherapies represents the standard of care for the treatment of this complic...
journal_title:Ophthalmic research
pub_type: 杂志文章,评审
doi:10.1159/000362764
更新日期:2014-01-01 00:00:00
abstract::The vibrating probe detects and measures currents around cells and organs. With its use, it is possible to demonstrate strong outward potassium currents at the equator of the lens and strong inward sodium currents at the optical poles. The addition of microelectrodes to the system permits one to define the nature of t...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000266570
更新日期:1988-01-01 00:00:00
abstract::The effect of large intake of dietary ascorbic acid on heat-induced eye lens protein damage has been studied. Male guinea pigs of the Hartley strain were used. Ascorbic acid was administered to the experimental animals in the drinking water. The mean daily ascorbic acid intakes for the control and experimental animals...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267008
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:Primary open-angle glaucoma (POAG) is a chronic progressive optic neuropathy, leading to degeneration of retinal ganglion cells and characteristic morphological changes at the optic disc. In advanced stages of the disease, functional tests, such as standard automated perimetry (SAP), are the main diagnostic too...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000501693
更新日期:2020-01-01 00:00:00
abstract::Dry eye is the most prominent pathology among those involving the ocular surface: a decrease of the aqueous (less frequent) or the lipid (more frequent) component of the tear film is the cause of the diminished stability of tears that is observed in this pathology. Dry eye shows a clear distribution linked to both sex...
journal_title:Ophthalmic research
pub_type: 杂志文章,评审
doi:10.1159/000489093
更新日期:2018-01-01 00:00:00
abstract::Extracellular recordings were performed on electrophysiologically identified achromatic neurons of the photosensitive pineal organ of the frog. The effects of iontophoretically applied aspartate and glutamate as well as one aspartate antagonist (D-alpha-aminoadipate) were observed on spontaneous activity and light-evo...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265304
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:To evaluate the effect of transpupillary thermotherapy (TTT) on foveal thickness and macular function in eyes with choroidal neovascularization (CNV) associated with age-related macular degeneration. METHODS:Sixteen eyes with occult CNV and 6 eyes with classic CNV were treated with TTT. Optical coherence tomog...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000083020
更新日期:2005-01-01 00:00:00
abstract::Exposure of mice to hyperbaric oxygen leads to an inhibition of the mitotic activity in the germinative epithelium of the lens. This is followed by an eventual development of cataracts. Cataracts have also been observed in human beings treated with hyperbaric oxygen for different afflictions. The lens damage and catar...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000266579
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND/AIMS:By the release of antiangiogenic factors, Müller glial cells provide an angiostatic environment in the normal and ischemic retina. We determined whether Müller cells produce thrombospondin-1 (TSP-1), a known inhibitor of angiogenesis. METHODS:Secretion of TSP-1 by cultured Müller cells was determined w...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000362371
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:Acute corneal permeability change after instillation of benzalkonium chloride (BAC) was evaluated using a newly developed in vivo corneal transepithelial electric resistance (TER) measurement method. METHOD:Corneal TER was measured by Ag/AgCl electrodes placed in the anterior aqueous chamber and on the corne...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000109986
更新日期:2007-01-01 00:00:00
abstract::The aim of the present study was to investigate biochemical and morphological changes in rat lenses following long-term UV B irradiation. After an irradiation period of 156 days with follow-up documentation by means of Scheimpflug photography, section-related biochemical analyses of the lenses as well as histological ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267187
更新日期:1992-01-01 00:00:00
abstract::The antioxidants sodium benzoate and 2,3-dihydroxybenzoic acid reduced the inflammatory response in experimental phacoanaphylactic endophthalmitis. The 2,3-dihydroxybenzoic acid was by far the more effective antiphlogistic agent. The molecular mechanisms that may have contributed to the observed difference in antiphlo...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265483
更新日期:1987-01-01 00:00:00
abstract::We examined the density and morphology of lens epithelial cells (LECs) in vivo in a group of normal volunteers and cataract patients by using a newly developed noncontact specular microscope. There was a statistically significant decrease in the cell density of LECs in a group of cataract patients over the age of 80 y...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000055694
更新日期:2001-11-01 00:00:00
abstract::The refractive indices in various rat retinal layers, based on the total dry mass concentration, ranged from 1.369 to 1.385. The ratios of the refractive indices of neighboring retinal layers were near unity. This finding suggests that light passes through the rat retina without much refraction. ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267223
更新日期:1993-01-01 00:00:00
abstract::Calf water-soluble (WS) crystallins consist of high-molecular weight (HM), alpha-, beta H-, beta L-, beta s- and gamma-crystallins. alpha-Crystallin as a molecular chaperone forms a structure with a central hole, known as Carver's model. The only crystallins fitting into this central cavity are beta s- and gamma-cryst...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267939
更新日期:1996-01-01 00:00:00
abstract::In a search for a pharmacologic adjuvant in the management of posttraumatic proliferative vitreoretinopathy (PVR), we investigated the effect of intravitreal injection of prinomastat (AG3340) on an experimental model. Posterior penetrating eye trauma was created in one eye each of 24 New Zealand white rabbits. One wee...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000055636
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:This study was performed to examine the location, width, and insertional shape of rectus extraocular muscles (EOMs), and to elucidate the symmetry of the insertional anatomy of rectus EOMs in the left and right eyes. METHODS:EOMs were dissected from their origin to the insertion point in 100 intact orbits of 5...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000272021
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To assess the natural variability in the diameter of small collagen fibrils in the lamellae of corneal stroma of healthy young rabbits. MATERIALS AND METHODS:The corneas of 6 young adult female New Zealand White rabbits (2.1 kg) were prepared for transmission electron microscopy (TEM) by fixation with a cacody...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000096228
更新日期:2006-01-01 00:00:00
abstract::Cannabinoid receptor involvement in the intraocular-pressure (IOP)-lowering effect of the cannabinoids has not been determined. These receptors bind four structural classes of agonists: the classical and the nonclassical cannabinoids, the aminoalkylindoles and the arachidonylethanolamides (the endogenous ligands). We ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267984
更新日期:1997-01-01 00:00:00
abstract::We examined 304 conjunctiva in 152 subjects by clinical, cytologic, and bacteriologic methods. Bacteriologic samples were evaluated after a 48-hour incubation. Bacterial growth was found in 8 (20.5%) of 39 patients with clinically normal conjunctiva and no polymorphonuclear leukocytes (PMNs), and in 8 (61.5%) of 13 su...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267086
更新日期:1991-01-01 00:00:00
abstract::We measured prostaglandin E2 (PGE2) and prostacyclin levels in the vitreous bodies of 5 eyes of patients with diabetic retinopathy complicated by rhegmatogenous retinal detachment (RRD) and compared them with the corresponding levels in 9 nondiabetic eyes with the same condition as well as with 10 control eyes of dece...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000266995
更新日期:1990-01-01 00:00:00
abstract:AIMS:To investigate whether allogeneic limbal mesenchymal stem cell (LMSC) therapy affects corneal healing after a severe chemical burn and whether the route of administration of LMSCs differs in its therapeutic effect in this respect. METHODS:A total of 60 Sprague-Dawley rats with clinically proven alkali injury were...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000368659
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the choroidal thickness (CT) and its determinants in primary angle closure glaucoma (PACG) eyes with and without malignant glaucoma (MG). METHODS:In this cross-sectional study, we enrolled 25 patients with bilateral primary angle closure (PAC) diseases; 1 eye of each patie...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000490914
更新日期:2018-01-01 00:00:00
abstract::Photodocumented measurements of the lens thickness using an EAS-1000 Scheimpflug camera were performed in 261 cataract eyes (162 pure type) compared with 52 control eyes. The lens thickness in normal eyes usually increased with age by 0.015 mm annually. The cataractous lens, especially in the anterior subcapsular type...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000267205
更新日期:1992-01-01 00:00:00
abstract::Ocular pneumoplethysmography was performed before and after 1,737 carotid endarterectomies, 82% of which were performed for carotid lesions of hemodynamic consequence. Preoperative ocular hypoperfusion without ischemia was associated with at least transient postoperative ocular hyperemia. A difference in ocular volume...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000055558
更新日期:1999-01-01 00:00:00