Acute corneal epithelial change after instillation of benzalkonium chloride evaluated using a newly developed in vivo corneal transepithelial electric resistance measurement method.

abstract：OBJECTIVE:Transient receptor potential canonical (TRPC) channels are involved in neovascularization repairing after vascular injury in many tissues. However, whether TRPCs play a regulatory role in the development of diabetic retinopathy (DR) has rarely been reported. In the present study, we selected TRPC1, 3, and 6 t...

journal_title：Ophthalmic research

authors： Lang HB,Xie RX,Huang ML,Fang LY,Tang YB,Zhang F

更新日期：2020-01-01 00:00:00

abstract：:Conventional Scheimpflug photography uses slits with a constant width of 80 microns. This parameter limits the resolution as sharp contours are imaged with a basic uncertainty. In order to reduce this basic uncertainty we developed an illumination slit with a width of 20 microns and less, using a green helium-neon las...

journal_title：Ophthalmic research

authors： Huebscher HJ,Möller DE,Seiler T

更新日期：1996-01-01 00:00:00

abstract：:L-Timolol (0.4 mg/kg) reduced significantly retinal blood flow (17%), systemic blood pressure (18-20%) and heart rate (28%) in the rabbit. D-Timolol (4.0 mg/kg) increased retinal blood flow slightly (9%) and did not significantly affect systemic blood pressure or heart rate. Since D-timolol is effective in reducing in...

journal_title：Ophthalmic research

authors： Yan HY,Chiou GC

更新日期：1987-01-01 00:00:00

abstract：:Rat lenses with experimentally induced cataract (either by naphthalene or by streptozotocin) were analyzed biochemically. Both noxae had some effects in common. Water-soluble protein and aldose reductase activity decreased, and glucose-6-phosphate dehydrogenase, phosphofructokinase and glutathione reductase activity i...

journal_title：Ophthalmic research

authors： Korte I,Hockwin O,Bours J,Wegener A

更新日期：1988-01-01 00:00:00

abstract：:Cannabinoid receptor involvement in the intraocular-pressure (IOP)-lowering effect of the cannabinoids has not been determined. These receptors bind four structural classes of agonists: the classical and the nonclassical cannabinoids, the aminoalkylindoles and the arachidonylethanolamides (the endogenous ligands). We ...

journal_title：Ophthalmic research

authors： Hodges LC,Reggio PH,Green K

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:The possibility of providing cultured corneal endothelial cells (CECs) for clinical transplantation has gained much attention. However, the worldwide need for human (h) donor corneas far exceeds supply. The pig (p) might provide an alternative source. The aim of this study was to compare the proliferative capac...

journal_title：Ophthalmic research

authors： Fujita M,Mehra R,Lee SE,Roh DS,Long C,Funderburgh JL,Ayares DL,Cooper DK,Hara H

更新日期：2013-01-01 00:00:00

abstract：:Ocular pneumoplethysmography was performed before and after 1,737 carotid endarterectomies, 82% of which were performed for carotid lesions of hemodynamic consequence. Preoperative ocular hypoperfusion without ischemia was associated with at least transient postoperative ocular hyperemia. A difference in ocular volume...

journal_title：Ophthalmic research

authors： Gee W,Reed JF 3rd

更新日期：1999-01-01 00:00:00

abstract：:The aim of the study was to examine the effects of nonsteroidal anti-inflammatory drugs (NSAIDs)/acetylsalicylic acid (ASA) on human lens epithelial cells (HLECs) during oxidative stress. HLECs were exposed to H2O2 in the absence or presence of indomethacin, diclofenac, celecoxib (NSAIDs) or ASA for 24 h. HLECs were a...

journal_title：Ophthalmic research

authors： Petersen A,Carlsson T,Karlsson JO,Zetterberg M

更新日期：2008-01-01 00:00:00

abstract：:The aim of the present study was to investigate biochemical and morphological changes in rat lenses following long-term UV B irradiation. After an irradiation period of 156 days with follow-up documentation by means of Scheimpflug photography, section-related biochemical analyses of the lenses as well as histological ...

journal_title：Ophthalmic research

authors： Schmidt J,Schmitt C,Kojima M,Hockwin O

更新日期：1992-01-01 00:00:00

abstract：:Topcon Tokyo manufactured the first series of SL-45 in 1980 and a second in 1982/83, which were completed in Bonn with all technical improvements developed so far. In 1987, the SL-45B was manufactured which included all previously added improvements. To compare both camera types, we carried out a test with 10 voluntee...

journal_title：Ophthalmic research

authors： Laser H,Berndt W,Leyendecker M,Kojima M,Hockwin O,Cheyne A

更新日期：1990-01-01 00:00:00

abstract：:Toxoplasma gondii is an extremely successful opportunistic parasite which infects approximately one third of the human population worldwide. The impact of this parasite on human health becomes particularly manifest in congenital damage with infection and subsequent inflammation of neuronal tissues including the retina...

journal_title：Ophthalmic research

authors： Pleyer U,Schlüter D,Mänz M

更新日期：2014-01-01 00:00:00

abstract：:Given the propensity of a large number of melanogenic pathways that can be modulated by cellular redox status, a causal role of the deficiency of ocular pigments such as melanin in the pathogenesis of age-related macular degeneration and evidence that melanin production does occur in the adult eye, it seems not improb...

journal_title：Ophthalmic research

authors： Sarangarajan R,Apte SP

更新日期：2004-11-01 00:00:00

abstract：:The component oxygen fluxes that constitute a single recording of corneal oxygen uptake when a polarographic oxygen sensor (POS) is placed in contact with the cornea were determined in the in vivo rabbit eye by removing the epithelium and injecting an air bubble into the anterior chamber. The relative contribution of ...

journal_title：Ophthalmic research

authors： Holden BA,Sulonen J,Vannas A,Sweeney DF,Efron N

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:This study was performed to examine the location, width, and insertional shape of rectus extraocular muscles (EOMs), and to elucidate the symmetry of the insertional anatomy of rectus EOMs in the left and right eyes. METHODS:EOMs were dissected from their origin to the insertion point in 100 intact orbits of 5...

journal_title：Ophthalmic research

authors： Cho HK,Shin SY

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of transpupillary thermotherapy (TTT) on foveal thickness and macular function in eyes with choroidal neovascularization (CNV) associated with age-related macular degeneration. METHODS:Sixteen eyes with occult CNV and 6 eyes with classic CNV were treated with TTT. Optical coherence tomog...

journal_title：Ophthalmic research

authors： Ishikawa K,Terasaki H,Kobayashi C,Niwa Y,Piao CH,Ito Y,Kondo M,Miyake Y

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:In this study, we used a rat model of retinal detachment (RD) to investigate the effects of transient receptor potential mucolipin 1 (TRPML1) on photoreceptor cells and the underlying mechanism. METHODS:An RD model was established by subretinal injection of sodium hyaluronate, and mucolipin synthetic agonist...

journal_title：Ophthalmic research

authors： Yan Y,Wang Y,Ding J,Lu L,Ke G,Dong K

更新日期：2020-10-07 00:00:00

abstract：:Although it is essential that intraocular pressure (IOP) be reduced in glaucoma treatment, it is also vitally important to provide sufficient blood flow to eye tissues so that healthy visual field is maintained. It is possible for an agent to reduce IOP and blood supply to the eye. In that case, glaucoma appears to be...

journal_title：Ophthalmic research

authors： Chiou GC,Yan HY

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To evaluate a technique of autologous internal limiting membrane (ILM) fragment transplantation for the treatment of large, chronic, and/or refractory macular holes (MH). DESIGN:This was a 6-month prospective interventional case series. METHOD:Ten eyes of 10 patients with MH underwent pars plana vitretomy (...

journal_title：Ophthalmic research

authors： De Novelli FJ,Preti RC,Ribeiro Monteiro ML,Pelayes DE,Junqueira Nóbrega M,Takahashi WY

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To propose a new noncontact tonometer based on corneal photoelasticity. METHOD:In this study, we experimented with 18 enucleated porcine eyes. The anterior chamber was infused with a physiological solution. A circular polarizing filter was attached to an ophthalmic surgical microscope. Color fringe changes at ...

journal_title：Ophthalmic research

authors： Hwang H,Kim M,Park C

更新日期：2011-01-01 00:00:00

abstract：:Vitamin E (d-alpha-tocopherol) and aspirin were evaluated for their effects on the phase separation temperature, Tc, of calf lens cytoplasm. Vitamin E and aspirin were added to nuclear homogenate and the change in Tc was measured. Aspirin had no measurable effect on Tc. Vitamin E lowered Tc at a rate of -22 degrees C ...

journal_title：Ophthalmic research

authors： Eccarius S,Clark JI

更新日期：1987-01-01 00:00:00

abstract：:This study developed a modified monolayer culture technique for expansion of retinal progenitor cells in vitro. Using this method, spheres collected by low centrifugation from free floating cultures were re-seeded onto poly-D-lysine pre-coated flasks, and cultured in the retinal progenitor cells medium (including fibr...

journal_title：Ophthalmic research

authors： Lai P,Tang S,Yi J,Zhu X,Zou Y,Xie H,Gao Y,Lin S

更新日期：2008-10-01 00:00:00

abstract：:A technique for chronic implantation of a device for long-term continuous, quantitative monitoring of intraocular pressure (IOP) in experimental animals is presented. The methodology employed is straight forward and should be easily duplicated for experimental investigations where such monitoring might be useful. Cont...

journal_title：Ophthalmic research

authors： Flower RW,Maumenee AE,Michelson EA

更新日期：1982-01-01 00:00:00

abstract：:Cataractous lens images taken with different camera types for retroillumination photography were compared. Images taken by conventional photo slitlamp and fundus cameras were not suitable for image analysis. Retroillumination photography with a conventional fundus camera with additional polarizing filters seemed to be...

journal_title：Ophthalmic research

authors： Sakamoto Y,Rankov G,Sasaki K

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the feasibility of a new technique for the implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium (RPE) cells into the subretinal space of retina-degenerate Royal College of Surgeon (RCS) rats. METHODS:A platform device was used for the implantation of 4-µm-t...

journal_title：Ophthalmic research

authors： Hu Y,Liu L,Lu B,Zhu D,Ribeiro R,Diniz B,Thomas PB,Ahuja AK,Hinton DR,Tai YC,Hikita ST,Johnson LV,Clegg DO,Thomas BB,Humayun MS

更新日期：2012-01-01 00:00:00

abstract：:The refractive indices in various rat retinal layers, based on the total dry mass concentration, ranged from 1.369 to 1.385. The ratios of the refractive indices of neighboring retinal layers were near unity. This finding suggests that light passes through the rat retina without much refraction. ...

journal_title：Ophthalmic research

authors： Chen E

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:Amblyopia is an important public health problem and standard screening is quite necessary for early diagnosis and treatment especially for the remote areas. As the place of the largest Tibetan population, the Tibetan Plateau has special geographical characteristics such as high altitude, time zone, and eth...

journal_title：Ophthalmic research

authors： Meng Z,Fu J,Chen W,Li L,Su H,Dai W,Yao Y

更新日期：2020-12-04 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the choroidal thickness (CT) and its determinants in primary angle closure glaucoma (PACG) eyes with and without malignant glaucoma (MG). METHODS:In this cross-sectional study, we enrolled 25 patients with bilateral primary angle closure (PAC) diseases; 1 eye of each patie...

journal_title：Ophthalmic research

authors： Chen X,Guo X,Xu X,Xiao H,Liu X

更新日期：2018-01-01 00:00:00

abstract：:The activities of sialyl-, fucosyl- and galactosyltransferase were measured in membrane preparations from bovine eyes. Radioactive sugars from CMP-N-neuraminic acid, GDP-fucose and UDP-galactose were incorporated into the endogenous and exogenous acceptors. The enzymatic activities of all three glycosyltransferases we...

journal_title：Ophthalmic research

authors： Unoki K,Uehara F,Muramatsu T

更新日期：1990-01-01 00:00:00

abstract：:Non-toxic concentrations of ceftazidime (CAZ), cefuzonam sodium (CZON) and cefmetazole sodium (CMZ) for intravitreal use were assessed by the electroretinogram in in vitro perfused eyecups of albino rabbits. None of the a-wave, the b-wave and the oscillatory potentials deteriorated with 300 microM CAZ, 300 microM CZON...

journal_title：Ophthalmic research

authors： Kitano K,Shirao Y,Kawasaki K

更新日期：1995-01-01 00:00:00

abstract：:HY-1 genotype chick lenses display epithelial hyperplasia and associated lens opacities. Membrane proteins from HY-1 and normal chick lenses were separated by isoelectric focusing, and 45Ca2+ binding capacities were determined. Markedly higher (congruent to 900-fold) binding of 45Ca2+ was observed in high molecular we...

journal_title：Ophthalmic research

authors： Odeigah PG,Patmore L

更新日期：1985-01-01 00:00:00