Changes of tear film function after pterygium operation.

abstract：:We studied lens opacification of rabbit lenses in culture. Opacification was produced by maintaining rabbit lenses in medium containing calcium concentrations as high as 10 mmol/l and the opacity was measured using LASER spectroscopy. Increasing calcium caused significant opacification in lens cortex while the transpa...

journal_title：Ophthalmic research

authors： Clark JI,Danford ME

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:To assess the cytotoxic properties of voriconazole and sulfobutylether-β-cyclodextrin (SBECD) on cultured primary human corneal epithelial cells. METHODS:Human corneal epithelial cells were cultured and exposed to various concentrations of SBECD (0.016-32 mg/ml) and voriconazole (0.001-2 mg/ml). Cellular cy...

journal_title：Ophthalmic research

authors： Sobolewska B,Guerel G,Hofmann J,Tarek B,Bartz-Schmidt KU,Yoeruek E

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The lens is the ocular structure most susceptible to oxidative damage. Antioxidants, micronutrients and phytochemicals have been extensively studied for their possible effects to prevent or delay the progression of various eye diseases. OBJECTIVES:A brief overview of the updated literature on the role of an...

journal_title：Ophthalmic research

authors： Agte V,Tarwadi K

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The pathogenesis of Behçet's disease (BD) may be related to excessive production of reactive oxygen species, activated neutrophils, and T lymphocytes. The goal of this prospective study was to investigate whether there is any relationship among the oxidant/antioxidant system and nitric oxide (NO) and malondia...

journal_title：Ophthalmic research

authors： Aydin E,Sögüt S,Ozyurt H,Ozugurlu F,Akyol O

更新日期：2004-05-01 00:00:00

abstract：:In order to investigate the combined influence of age and light, the b-wave and oscillatory potentials (OPs) of the electroretinogram (ERG) were recorded in 1.5-, 7- and 12-month-old WAG/Rij rats, reared under homogenous low-intensity cyclic light exposure. Wistar albino rats of the same ages, reared under the same co...

journal_title：Ophthalmic research

authors： Cillino S,Guarneri R,Guarneri P,Pennica C,Chichi G,Piccoli F,Ponte F

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:To examine melanocortin receptor (from MC-1 to MC-5) mRNA and the effect of alpha-melanocyte-stimulating hormone (alpha-MSH) on interleukin 8 (IL-8) and monocyte chemotactic protein 1 (MCP-1) expression in a human retinal pigment epithelial cell line (ARPE-19) stimulated with IL-1beta or tumor necrosis factor a...

journal_title：Ophthalmic research

authors： Cui HS,Hayasaka S,Zhang XY,Chi ZL,Hayasaka Y

更新日期：2005-09-01 00:00:00

abstract：:The development and extension of fibrovascular or fibroglial membranes onto the retinal surface are a major cause of visual loss in diabetic patients with proliferative retinopathy and in patients suffering from retinal detachment with proliferative vitreoretinopathy. The pathogenesis of these proliferative diseases, ...

journal_title：Ophthalmic research

authors： Fredj-Reygrobellet D,Baudouin C,Nègre F,Caruelle JP,Gastaud P,Lapalus P

更新日期：1991-01-01 00:00:00

abstract：:The eyes of 200 rats (Mol:SPRD, Moellegaard Ltd., Skensvet, Denmark), 8 weeks of age and of both sexes, were examined routinely with a photo-slitlamp microscope (Zeiss) and opthalmoscope (Heine) 3-4 times in the course of four different 12-week toxicity studies. The animals were kept under constant lighting conditions...

journal_title：Ophthalmic research

authors： Wegener A,Jochims K

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:This study was performed to examine the location, width, and insertional shape of rectus extraocular muscles (EOMs), and to elucidate the symmetry of the insertional anatomy of rectus EOMs in the left and right eyes. METHODS:EOMs were dissected from their origin to the insertion point in 100 intact orbits of 5...

journal_title：Ophthalmic research

authors： Cho HK,Shin SY

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:To compare intraocular pressure (IOP) measurements obtained with the digital tonometer TGDc-01 'PRA' with those from a Goldmann applanation tonometer (GAT). METHODS:The IOP in 176 eyes of 88 healthy volunteers was measured prospectively in a sitting position. One single measurement, generated by the TGDc-01...

journal_title：Ophthalmic research

authors： Meyer MW,Gockeln R,Hoy L,Meyer A,Erb C

更新日期：2004-09-01 00:00:00

abstract：AIMS:Mutations in the PAX6 are the major cause of congenital aniridia. The objective of this study was to analyze genetic mutations in PAX6 in Chinese patients with congenital aniridia. METHODS:Total genomic DNA was isolated from the peripheral blood of the aniridia patients, all healthy family members and 100 healthy...

journal_title：Ophthalmic research

authors： Luo F,Zhou L,Ma X,He Y,Zou L,Jie Y,Liu J,Pan Z

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To characterize the 1-year progression of retinal thickness (RT) increase occurring in eyes with subclinical macular edema in type 2 diabetes. METHODS:Forty-eight type 2 diabetic eyes/patients with mild nonproliferative diabetic retinopathy (NPDR; levels 20 and 35 in the Early Treatment Diabetic Retinopathy St...

journal_title：Ophthalmic research

authors： Tejerina AN,Vujosevic S,Varano M,Egan C,Sivaprasad S,Menon G,Massin P,Verbraak FD,Lund-Andersen H,Martinez JP,Jurgens I,Smets E,Coriat C,Wiedemann P,Ágoas V,Querques G,Holz FG,Nunes S,Alves D,Neves C,Santos T,Ri

更新日期：2015-01-01 00:00:00

abstract：:Using cuprolinic blue staining, we histochemically examined the ultrastructural localization of proteoglycans in the fibrous-type human posterior capsule opacification. This capsule opacification contained proteoglycans that showed positive staining with cuprolinic blue. Many cuprolinic-blue-positive filaments were pr...

journal_title：Ophthalmic research

authors： Ishibashi T,Araki H,Sugai S,Tawara A,Inomata H

更新日期：1995-01-01 00:00:00

abstract：:Conventional Scheimpflug photography uses slits with a constant width of 80 microns. This parameter limits the resolution as sharp contours are imaged with a basic uncertainty. In order to reduce this basic uncertainty we developed an illumination slit with a width of 20 microns and less, using a green helium-neon las...

journal_title：Ophthalmic research

authors： Huebscher HJ,Möller DE,Seiler T

更新日期：1996-01-01 00:00:00

abstract：:A technique for chronic implantation of a device for long-term continuous, quantitative monitoring of intraocular pressure (IOP) in experimental animals is presented. The methodology employed is straight forward and should be easily duplicated for experimental investigations where such monitoring might be useful. Cont...

journal_title：Ophthalmic research

authors： Flower RW,Maumenee AE,Michelson EA

更新日期：1982-01-01 00:00:00

abstract：:The topographic distribution of enzyme activities in normal rat lenses and their changes occurring during naphthalene cataract development were investigated. Cataract formation was documented by slit images according to the Scheimpflug principle. Before the onset of visible changes and after the development of early v...

journal_title：Ophthalmic research

authors： Kojima M

更新日期：1992-01-01 00:00:00

abstract：:The refractive indices in various rat retinal layers, based on the total dry mass concentration, ranged from 1.369 to 1.385. The ratios of the refractive indices of neighboring retinal layers were near unity. This finding suggests that light passes through the rat retina without much refraction. ...

journal_title：Ophthalmic research

authors： Chen E

更新日期：1993-01-01 00:00:00

abstract：:HY-1 genotype chick lenses display epithelial hyperplasia and associated lens opacities. Membrane proteins from HY-1 and normal chick lenses were separated by isoelectric focusing, and 45Ca2+ binding capacities were determined. Markedly higher (congruent to 900-fold) binding of 45Ca2+ was observed in high molecular we...

journal_title：Ophthalmic research

authors： Odeigah PG,Patmore L

更新日期：1985-01-01 00:00:00

abstract：:Tear hyperosmolarity is known to cause ocular surface inflammation in dry eye syndrome. Benzalkonium chloride (BAK), an eyedrop preservative, is known to induce dry eye in long-term-treated patients. Analyzing the modulation of the proinflammatory potential of hyperosmolarity in the presence of BAK on the conjunctiva ...

journal_title：Ophthalmic research

authors： Warcoin E,Clouzeau C,Roubeix C,Raveu AL,Godefroy D,Riancho L,Baudouin C,Brignole-Baudouin F

更新日期：2017-01-01 00:00:00

abstract：:The main objective of this study was to determine the intraocular concentration of fluorescein after applying five eye drops with only 1-min intervals in human eyes. The concentration of fluorescein in corea and aqueous was studied with fluorophotometry in 11 healthy volunteers. Five 10-microliter drops of 2% fluoresc...

journal_title：Ophthalmic research

authors： Lindén C,Alm A

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:The aim of the present study was to characterize the development of after-cataract in the rabbit by measuring its wet weight, protein, DNA and glycosaminoglycan (GAG) contents and using Scheimpflug and slitlamp analysis. Further, aqueous humor (AqH) leukocytes, protein and lens epithelial cell proliferation act...

journal_title：Ophthalmic research

authors： Wallentin N,Lundgren B,Holmén JB,Lundberg C

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:To assess the natural variability in the diameter of small collagen fibrils in the lamellae of corneal stroma of healthy young rabbits. MATERIALS AND METHODS:The corneas of 6 young adult female New Zealand White rabbits (2.1 kg) were prepared for transmission electron microscopy (TEM) by fixation with a cacody...

journal_title：Ophthalmic research

authors： Doughty MJ,Bergmanson JP

更新日期：2006-01-01 00:00:00

abstract：:Correlation proton nuclear magnetic resonance spectroscopy was performed on light- and dark-adapted rabbit retinas to elucidate real-time hexose monophosphate shunt (HMPS) activity. Light significantly stimulated retinal HMPS initially, which consumed 17% more glucose than that in dark-adapted retinas. The glucose con...

journal_title：Ophthalmic research

authors： Aguiar E,Cheng HM,Lam DM

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:Extensive clinical investigations of the biocompatibility of different intraocular lenses (IOLs) have been made in an effort to optimize the outcome of modern cataract surgery. The aim of this study was to add animal eye experimental implantation data regarding cellular reaction on the anterior surface of IOLs....

journal_title：Ophthalmic research

authors： Barbour W,Saika S,Miyamoto T,Ohnishi Y

更新日期：2005-09-01 00:00:00

abstract：:In a search for a pharmacologic adjuvant in the management of posttraumatic proliferative vitreoretinopathy (PVR), we investigated the effect of intravitreal injection of prinomastat (AG3340) on an experimental model. Posterior penetrating eye trauma was created in one eye each of 24 New Zealand white rabbits. One wee...

journal_title：Ophthalmic research

authors： Ozerdem U,Mach-Hofacre B,Keefe K,Pham T,Soules K,Appelt K,Freeman WR

更新日期：2001-01-01 00:00:00

abstract：:Energy-dispersive X-ray analysis was used to obtain distribution profiles of Na, K, Cl, P and S in rapidly frozen-dried bulk specimens, and in cryosections of the normal rat lens. Na and Cl are highly concentrated in the capsule, and K and P, in the epithelial cells. Profiles of the entire radius of a lens show relati...

journal_title：Ophthalmic research

authors： Harding CV,Susan S,Bobrowski W

更新日期：1984-01-01 00:00:00

abstract：AIMS:Staphylococcus epidermidis is considered a commensal bacterium; however, it is frequently isolated from ocular infections showing a multidrug resistance. Ciprofloxacin-resistant strains have been isolated from ocular infections; however, resistance to quinolone, such as gatifloxacin and moxifloxacin, is not often ...

journal_title：Ophthalmic research

authors： Betanzos-Cabrera G,Juárez-Verdayes MA,González-González G,Cancino-Díaz ME,Cancino-Díaz JC

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Retinitis pigmentosa (RP) is an inherited retinal disorder, characterized by photoreceptor degeneration inducing progressive vision loss. This study evaluates its impact on quality of life (QOL) and emotional states of patients affected by RP. METHODS:A cross-sectional study was conducted on 60 RP patient...

journal_title：Ophthalmic research

authors： Azoulay L,Chaumet-Riffaud P,Jaron S,Roux C,Sancho S,Berdugo N,Audo I,Sahel JA,Mohand-Saïd S

更新日期：2015-01-01 00:00:00

abstract：:Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis. We already identified and characterized novel autoantigens (malate dehydrogenase, recoverin, CRALBP) by analyzing the autoantibody...

journal_title：Ophthalmic research

authors： Deeg CA,Hauck SM,Amann B,Pompetzki D,Altmann F,Raith A,Schmalzl T,Stangassinger M,Ueffing M

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:The traditional medium for storing corneas in European Eye Banks is Gibco's MEM (Eagle's) with Earle's salts and Hepes containing 2% fetal calf serum, glutamine and antimycotics. Although serum-free MegaCell MEM has been reported to be more suitable for this purpose, it contains components of animal origin that...

journal_title：Ophthalmic research

authors： Smith VA,Johnson T

更新日期：2010-01-01 00:00:00