Low temperature and acrylamide inhibit lens opacification caused by calcium.

Abstract:

:We studied lens opacification of rabbit lenses in culture. Opacification was produced by maintaining rabbit lenses in medium containing calcium concentrations as high as 10 mmol/l and the opacity was measured using LASER spectroscopy. Increasing calcium caused significant opacification in lens cortex while the transparency in lens nucleus was unchanged by these concentrations. The cortical opacity was inhibited by low temperature and acrylamide. The maximum inhibition of opacity occurred at a concentration of 1% acrylamide and a temperature of 4 degrees C. The opacification due to a phase separation in nuclear cells was unaffected by these concentrations of calcium.

journal_name

Ophthalmic Res

journal_title

Ophthalmic research

authors

Clark JI,Danford ME

doi

10.1159/000265380

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

246-50

issue

4

eissn

0030-3747

issn

1423-0259

journal_volume

17

pub_type

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