Abstract:
PURPOSE:To determine the effect of placing a pneumatic suction ring on intraocular pressure (IOP) in the cat and to design an improved method to generate a stable elevation of IOP. METHODS:A pneumatic suction ring was applied to the eye in cats while the IOP was monitored. Three groups of animals (10 per group) were used. A vacuum pressure of 450 mbar was applied in one step to eyes of group 1 (anesthetized) and to group 2 (euthanized) cats. In group 3 (anesthetized) cats, an initial vacuum pressure of 250 mbar was applied, followed by a vacuum of slowly increasing pressure at a rate of 5 mbar/min for a total of 40 min to 450 mbar. RESULTS:After the one-step application of a vacuum (450 mbar) to the eyes of anesthetized cats (group 1), IOP peaked within the first minute from a basal value of 25 +/- 2 mm Hg (mean +/- SD) to 90 +/- 7 mm Hg. It then rapidly decreased to 69 +/- 2 mm Hg 5 min later and continued to decrease to 39 +/- 4 mm Hg 40 min later. This sharp peak and decline of IOP were also observed in eyes of euthanized cats (group 2). The basal IOP of these eyes was 8 +/- 1 mm Hg. It rose to 18 +/- 2 mm Hg immediately after the application of vacuum pressure (450 mbar) and returned to the basal level 5 min later. In contrast, the eyes of group 3 receiving an initial vacuum of 250 mbar followed by a 5 mbar/min vacuum increment exhibited a rapid increase in IOP and a very stable plateau (mean IOP = 62-68 mm Hg), lasting the whole study period (40 min). CONCLUSION:IOP after a one-step application of a vacuum via a pneumatic suction ring is self-adjusting and declines rapidly over time. This decline in IOP can be overcome by a supplementary increment in vacuum pressure.
journal_name
Ophthalmic Resjournal_title
Ophthalmic researchauthors
Li Bdoi
10.1159/000055680subject
Has Abstractpub_date
2001-09-01 00:00:00pages
271-5issue
5eissn
0030-3747issn
1423-0259pii
55680journal_volume
33pub_type
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更新日期:1983-01-01 00:00:00
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更新日期:1988-01-01 00:00:00