Bupranolol, a beta 1- and beta 2-blocker, causes constriction of the pupil in men.

abstract：:A technique for chronic implantation of a device for long-term continuous, quantitative monitoring of intraocular pressure (IOP) in experimental animals is presented. The methodology employed is straight forward and should be easily duplicated for experimental investigations where such monitoring might be useful. Cont...

journal_title：Ophthalmic research

authors： Flower RW,Maumenee AE,Michelson EA

更新日期：1982-01-01 00:00:00

abstract：AIM:Ultraviolet (UV) B irradiation induces gene expression that leads to skin cancer. Among the transcription factors induced by UVB radiation exposure, the cyclic AMP response element-binding protein (CREB) is significant. Since several factors downstream of CREB signaling are known to be involved in pterygium pathoge...

journal_title：Ophthalmic research

authors： Nubile M,Curcio C,Lanzini M,Calienno R,Iezzi M,Mastropasqua A,Di Nicola M,Mastropasqua L

更新日期：2013-01-01 00:00:00

abstract：:Diabetic macular edema is a common condition frequently encountered by ophthalmologists. In this piece we briefly review its definition, pathogenesis, clinical aspects, imaging, and treatment. ...

journal_title：Ophthalmic research

authors： Moisseiev E,Loewenstein A

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Amblyopia is an important public health problem and standard screening is quite necessary for early diagnosis and treatment especially for the remote areas. As the place of the largest Tibetan population, the Tibetan Plateau has special geographical characteristics such as high altitude, time zone, and eth...

journal_title：Ophthalmic research

authors： Meng Z,Fu J,Chen W,Li L,Su H,Dai W,Yao Y

更新日期：2020-12-04 00:00:00

abstract：:Metabolic changes in the rabbit lens have been studied by means of nuclear magnetic resonance spectroscopy. These changes have been induced by prolonged topical treatment with dexamethasone. Our results demonstrate an increase in sorbitol, sorbitol-3-phosphate, fructose-3-phosphate, glycerol-3-phosphate and glucose-6-...

journal_title：Ophthalmic research

authors： Pescosolido N,Miccheli A,Manetti C,Iannetti GD,Feher J,Cavallotti C

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:Single-field non-mydriatic fundus photography (NMFP) has been used to detect diabetic retinopathy (DR) in many studies; however, its value in a general clinical setting has not been established. Here we performed a meta-analysis to evaluate its diagnostic effectiveness. METHOD:We systematically searched PubMed...

journal_title：Ophthalmic research

authors： Hu J,Chen R,Lu Y,Dou X,Ye B,Cai Z,Pu Z,Mou L

更新日期：2019-01-01 00:00:00

abstract：:We measured prostaglandin E2 (PGE2) and prostacyclin levels in the vitreous bodies of 5 eyes of patients with diabetic retinopathy complicated by rhegmatogenous retinal detachment (RRD) and compared them with the corresponding levels in 9 nondiabetic eyes with the same condition as well as with 10 control eyes of dece...

journal_title：Ophthalmic research

authors： Naveh N,Belkin M,Ben-Chaim O,Weissman C,Treister G

更新日期：1990-01-01 00:00:00

abstract：:Energy-dispersive X-ray analysis was used to obtain distribution profiles of Na, K, Cl, P and S in rapidly frozen-dried bulk specimens, and in cryosections of the normal rat lens. Na and Cl are highly concentrated in the capsule, and K and P, in the epithelial cells. Profiles of the entire radius of a lens show relati...

journal_title：Ophthalmic research

authors： Harding CV,Susan S,Bobrowski W

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:To investigate the effect of propolis, a natural resin produced by honeybees, in the treatment of alkali-injured rabbit eyes. METHOD:A corneal alkali burn was induced by applying filter paper immersed in 1 N NaOH on the central axis of the right corneas of 24 rabbits for 30 s. The animals were divided into thr...

journal_title：Ophthalmic research

authors： Oztürk F,Kurt E,Cerçi M,Emiroglu L,Inan U,Türker M,Ilker S

更新日期：2000-01-01 00:00:00

abstract：:A system for isolation of capillaries from the retina has been adapted to biochemical studies in vitro. Insulin receptors were identified in human and calf retinal blood vessels. Binding of 125I insulin by calf retinal blood vessels takes place through high affinity (low capacity) and low affinity (high capacity) rece...

journal_title：Ophthalmic research

authors： Cotlier E,Davidson C

更新日期：1983-01-01 00:00:00

abstract：:Age-related lens opacity is the major cause of loss of vision affecting more than half of the world's blind. The development of cataract is associated with changes in the structure of the lens. The lens consists largely of closely packed fibre cells forming a transparent syncytium. The main intrinsic polypeptide (MIP)...

journal_title：Ophthalmic research

authors： Lea EJ

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To evaluate a technique of autologous internal limiting membrane (ILM) fragment transplantation for the treatment of large, chronic, and/or refractory macular holes (MH). DESIGN:This was a 6-month prospective interventional case series. METHOD:Ten eyes of 10 patients with MH underwent pars plana vitretomy (...

journal_title：Ophthalmic research

authors： De Novelli FJ,Preti RC,Ribeiro Monteiro ML,Pelayes DE,Junqueira Nóbrega M,Takahashi WY

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Retinitis pigmentosa (RP) is an inherited retinal disorder, characterized by photoreceptor degeneration inducing progressive vision loss. This study evaluates its impact on quality of life (QOL) and emotional states of patients affected by RP. METHODS:A cross-sectional study was conducted on 60 RP patient...

journal_title：Ophthalmic research

authors： Azoulay L,Chaumet-Riffaud P,Jaron S,Roux C,Sancho S,Berdugo N,Audo I,Sahel JA,Mohand-Saïd S

更新日期：2015-01-01 00:00:00

abstract：:To evaluate the possible role of nitric oxide in the pathogenesis of exogenous prostaglandin (PG) induced aqueous flare elevation, we examined the effect of NG-nitro-L-arginine methyl ester (L-NAME), an L-arginine analogue acting as a specific inhibitor of nitric oxide synthase, on the elevation of aqueous flare in pi...

journal_title：Ophthalmic research

authors： Hiraki S,Zhang XY,Hayasaka S

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:This study was aimed at determining the intraocular pharmacokinetics based on molecular physicochemical properties in a rabbit model. METHODS:The entire dataset was obtained from previous literature, and research articles regarding 70 molecular compounds were investigated. The intravitreal half-lives in rabbit...

journal_title：Ophthalmic research

authors： Kim HM,Park KH,Chung JY,Woo SJ

更新日期：2020-01-01 00:00:00

abstract：:To ascertain the effectiveness of topical antioxidant therapy on acute corneal inflammation, we have studied the effectiveness of topical treatment with a saline solution and with antioxidants such as 0.2% superoxide dismutase and 0.5% dimethylthiourea (DMTU) in a controlled experimental study. The evolution of the in...

journal_title：Ophthalmic research

authors： Alio JL,Ayala MJ,Mulet ME,Artola A,Ruiz JM,Bellot J

更新日期：1995-01-01 00:00:00

abstract：:Conventional Scheimpflug photography uses slits with a constant width of 80 microns. This parameter limits the resolution as sharp contours are imaged with a basic uncertainty. In order to reduce this basic uncertainty we developed an illumination slit with a width of 20 microns and less, using a green helium-neon las...

journal_title：Ophthalmic research

authors： Huebscher HJ,Möller DE,Seiler T

更新日期：1996-01-01 00:00:00

abstract：:Photodocumented measurements of the lens thickness using an EAS-1000 Scheimpflug camera were performed in 261 cataract eyes (162 pure type) compared with 52 control eyes. The lens thickness in normal eyes usually increased with age by 0.015 mm annually. The cataractous lens, especially in the anterior subcapsular type...

journal_title：Ophthalmic research

authors： Shyn KH,Kim HC,Kim JC

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:The traditional medium for storing corneas in European Eye Banks is Gibco's MEM (Eagle's) with Earle's salts and Hepes containing 2% fetal calf serum, glutamine and antimycotics. Although serum-free MegaCell MEM has been reported to be more suitable for this purpose, it contains components of animal origin that...

journal_title：Ophthalmic research

authors： Smith VA,Johnson T

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Weak oxidants produced by activated human leukocytes are proven antimicrobial substances. We tested whether N-chlorotaurine (NCT, taurine chloramine), the chlorinated metabolite of the amino acid taurine, in addition to direct virucidal effects on viral suspensions, has the capability to prevent cell-to-cell ...

journal_title：Ophthalmic research

authors： Huemer HP,Nagl M,Irschick EU

更新日期：2010-01-01 00:00:00

abstract：:The effect of topical neutral formaldehyde on the blood-aqueous barrier of the rat was studied. Thirty minutes after irritation, the protein concentration of the aqueous humour had increased from the control value of 1.95 +/- 0.25 to 2.95 +/- 0.45 mg/ml (p less than 0.05). Extravasation of Evans blue dye from the iris...

journal_title：Ophthalmic research

authors： Krootila K,Uusitalo H,Lehtosalo JI,Palkama A

更新日期：1986-01-01 00:00:00

abstract：:The specific activities of the four investigated enzymes of the carbohydrate metabolism decrease with ageing. In the old tissue, phosphoglyceratemutase and enolase sustain changes in their molecular weight, and their substrate affinity is modified. ...

journal_title：Ophthalmic research

authors： Ohrloff C,Berdjis H,Hockwin O,Bours J

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The aim of this work was to compare the efficacy of intravitreal dexamethasone implant (Ozurdex) and intravitreal ranibizumab (Lucentis) in the treatment of macular edema (ME) caused by retinal vein occlusion (RVO). METHODS:Thirty-two ME cases treated with Ozurdex and 32 ME cases treated with ranibizumab we...

journal_title：Ophthalmic research

authors： Gu X,Yu X,Song S,Dai H

更新日期：2017-01-01 00:00:00

abstract：:We studied lens opacification of rabbit lenses in culture. Opacification was produced by maintaining rabbit lenses in medium containing calcium concentrations as high as 10 mmol/l and the opacity was measured using LASER spectroscopy. Increasing calcium caused significant opacification in lens cortex while the transpa...

journal_title：Ophthalmic research

authors： Clark JI,Danford ME

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Myopia has become a worldwide public health issue, which is occurring at a younger age, leading to an increased risk of high myopia. Ocular complications associated with high myopia can lead to irreversible vision loss. It is urgent and critical to explore effective treatment to slow or even stop the progres...

journal_title：Ophthalmic research

authors： Wang S,Wang J,Wang N

更新日期：2020-08-11 00:00:00

abstract：PURPOSE:To examine melanocortin receptor (from MC-1 to MC-5) mRNA and the effect of alpha-melanocyte-stimulating hormone (alpha-MSH) on interleukin 8 (IL-8) and monocyte chemotactic protein 1 (MCP-1) expression in a human retinal pigment epithelial cell line (ARPE-19) stimulated with IL-1beta or tumor necrosis factor a...

journal_title：Ophthalmic research

authors： Cui HS,Hayasaka S,Zhang XY,Chi ZL,Hayasaka Y

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:To assess and describe sequential morphological changes in the choroidal neovascularization (CNV) net using optical coherence tomography angiography (OCTA) in patients undergoing treatment with intravitreal antivascular endothelial growth factor (VEGF). METHODS:Prospective cohort study. OCTA was performed sequ...

journal_title：Ophthalmic research

authors： Marques JP,Costa JF,Marques M,Cachulo ML,Figueira J,Silva R

更新日期：2016-01-01 00:00:00

abstract：:Rat lenses with experimentally induced cataract (either by naphthalene or by streptozotocin) were analyzed biochemically. Both noxae had some effects in common. Water-soluble protein and aldose reductase activity decreased, and glucose-6-phosphate dehydrogenase, phosphofructokinase and glutathione reductase activity i...

journal_title：Ophthalmic research

authors： Korte I,Hockwin O,Bours J,Wegener A

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:This study was performed to examine the location, width, and insertional shape of rectus extraocular muscles (EOMs), and to elucidate the symmetry of the insertional anatomy of rectus EOMs in the left and right eyes. METHODS:EOMs were dissected from their origin to the insertion point in 100 intact orbits of 5...

journal_title：Ophthalmic research

authors： Cho HK,Shin SY

更新日期：2010-01-01 00:00:00

abstract：:The pineal organ of the pike is a functional photoreceptive organ in which a multiplicity of the cells of the receptor line (CRL i.e. typical and modified photoreceptors) was demonstrated. The CRL appeared to be (i) regionally distributed, (ii) photosensitive, and (iii) responsible for the storage of various indoles (...

journal_title：Ophthalmic research

authors： Falcón J

更新日期：1984-01-01 00:00:00