Photosensitivity and biosynthesis of indole compounds in the cells of the receptor line of the pineal organ of the pike.

abstract：:Non-toxic concentrations of ceftazidime (CAZ), cefuzonam sodium (CZON) and cefmetazole sodium (CMZ) for intravitreal use were assessed by the electroretinogram in in vitro perfused eyecups of albino rabbits. None of the a-wave, the b-wave and the oscillatory potentials deteriorated with 300 microM CAZ, 300 microM CZON...

journal_title：Ophthalmic research

authors： Kitano K,Shirao Y,Kawasaki K

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:To assess the natural variability in the diameter of small collagen fibrils in the lamellae of corneal stroma of healthy young rabbits. MATERIALS AND METHODS:The corneas of 6 young adult female New Zealand White rabbits (2.1 kg) were prepared for transmission electron microscopy (TEM) by fixation with a cacody...

journal_title：Ophthalmic research

authors： Doughty MJ,Bergmanson JP

更新日期：2006-01-01 00:00:00

abstract：:A technique for chronic implantation of a device for long-term continuous, quantitative monitoring of intraocular pressure (IOP) in experimental animals is presented. The methodology employed is straight forward and should be easily duplicated for experimental investigations where such monitoring might be useful. Cont...

journal_title：Ophthalmic research

authors： Flower RW,Maumenee AE,Michelson EA

更新日期：1982-01-01 00:00:00

abstract：AIMS:Staphylococcus epidermidis is considered a commensal bacterium; however, it is frequently isolated from ocular infections showing a multidrug resistance. Ciprofloxacin-resistant strains have been isolated from ocular infections; however, resistance to quinolone, such as gatifloxacin and moxifloxacin, is not often ...

journal_title：Ophthalmic research

authors： Betanzos-Cabrera G,Juárez-Verdayes MA,González-González G,Cancino-Díaz ME,Cancino-Díaz JC

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To characterize the 1-year progression of retinal thickness (RT) increase occurring in eyes with subclinical macular edema in type 2 diabetes. METHODS:Forty-eight type 2 diabetic eyes/patients with mild nonproliferative diabetic retinopathy (NPDR; levels 20 and 35 in the Early Treatment Diabetic Retinopathy St...

journal_title：Ophthalmic research

authors： Tejerina AN,Vujosevic S,Varano M,Egan C,Sivaprasad S,Menon G,Massin P,Verbraak FD,Lund-Andersen H,Martinez JP,Jurgens I,Smets E,Coriat C,Wiedemann P,Ágoas V,Querques G,Holz FG,Nunes S,Alves D,Neves C,Santos T,Ri

更新日期：2015-01-01 00:00:00

abstract：:Rat lenses with experimentally induced cataract (either by naphthalene or by streptozotocin) were analyzed biochemically. Both noxae had some effects in common. Water-soluble protein and aldose reductase activity decreased, and glucose-6-phosphate dehydrogenase, phosphofructokinase and glutathione reductase activity i...

journal_title：Ophthalmic research

authors： Korte I,Hockwin O,Bours J,Wegener A

更新日期：1988-01-01 00:00:00

abstract：:To ascertain the effectiveness of topical antioxidant therapy on acute corneal inflammation, we have studied the effectiveness of topical treatment with a saline solution and with antioxidants such as 0.2% superoxide dismutase and 0.5% dimethylthiourea (DMTU) in a controlled experimental study. The evolution of the in...

journal_title：Ophthalmic research

authors： Alio JL,Ayala MJ,Mulet ME,Artola A,Ruiz JM,Bellot J

更新日期：1995-01-01 00:00:00

abstract：:In an experimental study using freshly enucleated pig's eyes, we investigated the endothelial cell loss on the cut edge. Remote-control rotating trephine was found to be the least injuring when it was applied to fresh and preserved human corneas. Corneal culture does not seem to enhance endothelial cell damage due to ...

journal_title：Ophthalmic research

authors： Böhnke M,Draeger J,Niesmann U

更新日期：1982-01-01 00:00:00

abstract：:To evaluate the effect of single or repeated topical applications of prostaglandin E2 (PGE2) to the cornea on the blood-aqueous barrier, we have measured the extent of flare in the anterior chamber of rabbit eyes at various time intervals. PGE2 was applied to the cornea for 4 min with the use of a glass cylinder in pi...

journal_title：Ophthalmic research

authors： Numata-Watanabe K,Hirata H,Hiraki S,Hayasaka S

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To study the ability to appreciate qualitative features that indicate disease activity in patients with neovascular age-related macular degeneration (AMD) and to analyze the differences in automated retinal thickness measurement, using 1 time domain optical coherence tomography (TD-OCT) and 2 different spectral...

journal_title：Ophthalmic research

authors： Querques G,Forte R,Berboucha E,Martinelli D,Coscas G,Soubrane G,Souied EH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:We assessed bleb morphology and the intraocular pressure (IOP)-lowering effect of trabeculectomy with ologen compared to mitomycin C (MMC) in juvenile open-angle glaucoma (JOAG). METHODS:This is a prospective interventional comparative study conducted on 40 eyes (20 patients) with medically uncontrolled JOA...

journal_title：Ophthalmic research

authors： El-Sayyad F,El-Saied HMA,Abdelhakim MASE

更新日期：2017-01-01 00:00:00

abstract：:The tear levels of cholesterol of 17 patients with chronic blepharitis and 17 healthy subjects were determined by the photometric method. The mean cholesterol level of the patients was determined to be 56.1 +/- 8.9 (SEM) mg/dl. No statistically significant difference between the tear cholesterol levels of the two grou...

journal_title：Ophthalmic research

authors： Saatçi AO,Irkeç M,Unlü N

更新日期：1990-01-01 00:00:00

abstract：:Exposure of mice to hyperbaric oxygen leads to an inhibition of the mitotic activity in the germinative epithelium of the lens. This is followed by an eventual development of cataracts. Cataracts have also been observed in human beings treated with hyperbaric oxygen for different afflictions. The lens damage and catar...

journal_title：Ophthalmic research

authors： Varma SD,Richards RD

更新日期：1988-01-01 00:00:00

abstract：INTRODUCTION:The aim of this work was to describe the optical coherence tomography (OCT) angiography (OCTA) features in paediatric Leber-Coats disease. METHODS:Three children presenting with unilateral, clinically active Leber-Coats disease were evaluated using spectral domain OCT and OCTA. OCT angiograms were analyse...

journal_title：Ophthalmic research

authors： Fortunato M,Turtoro A,Cennamo G

更新日期：2017-01-01 00:00:00

abstract：:The effect of topical neutral formaldehyde on the blood-aqueous barrier of the rat was studied. Thirty minutes after irritation, the protein concentration of the aqueous humour had increased from the control value of 1.95 +/- 0.25 to 2.95 +/- 0.45 mg/ml (p less than 0.05). Extravasation of Evans blue dye from the iris...

journal_title：Ophthalmic research

authors： Krootila K,Uusitalo H,Lehtosalo JI,Palkama A

更新日期：1986-01-01 00:00:00

abstract：:The polyamines putrescine, spermidine and spermine have been proposed to be a part of the acute phase inflammatory response. They have been shown to be useful markers for cellular kinetics and change with various pathological conditions. The hypothesis that aqueous humor polyamines could be used to follow the time cou...

journal_title：Ophthalmic research

authors： Wickström K,Lundgren B,Törngren L,Ostberg C

更新日期：1992-01-01 00:00:00

abstract：:Substance P (SP) immunoreactivity was demonstrated using the indirect immunofluorescence technique in one normal and one retinoblastomatous human retina. In the normal retina SP immunoreaction was located in nerve fibres but not in the neurons in the inner plexiform layer. A similar location was observed in the histol...

journal_title：Ophthalmic research

authors： Tarkkanen A,Tervo T,Tervo K,Eränkö L,Eränkö O,Cuello AC

更新日期：1983-01-01 00:00:00

abstract：AIM:To develop a local approach to study rabbit lacrimal secretion in situ by administering specific secretagogues directly onto the lacrimal gland (LG). METHODS:After the rabbit has been anesthetized, the inferior bulbar conjunctiva and underlying connective tissue are blunt dissected. A polyethylene tube, for drug d...

journal_title：Ophthalmic research

authors： Ding C,Rife L,Nakamura T,Wang YW,Kopp K,Schechter JE

更新日期：2008-01-01 00:00:00

abstract：:Calf water-soluble (WS) crystallins consist of high-molecular weight (HM), alpha-, beta H-, beta L-, beta s- and gamma-crystallins. alpha-Crystallin as a molecular chaperone forms a structure with a central hole, known as Carver's model. The only crystallins fitting into this central cavity are beta s- and gamma-cryst...

journal_title：Ophthalmic research

authors： Bours J

更新日期：1996-01-01 00:00:00

abstract：:Diabetic macular edema is a common condition frequently encountered by ophthalmologists. In this piece we briefly review its definition, pathogenesis, clinical aspects, imaging, and treatment. ...

journal_title：Ophthalmic research

authors： Moisseiev E,Loewenstein A

更新日期：2017-01-01 00:00:00

abstract：AIMS:Experimental retinal research has gained great importance due to the ophthalmic pharmacotherapy era. An increasing number of drugs are constantly released into the market for the treatment of retinal diseases. In this review, animal species, animal models and toxicity assays in retinal research are discussed. MET...

journal_title：Ophthalmic research

authors： Penha FM,Rodrigues EB,Maia M,Dib E,Fiod Costa E,Furlani BA,Nunes Moraes Filho M,Dreyfuss JL,Bottós J,Farah ME

更新日期：2010-01-01 00:00:00

abstract：:Chloroquine retinopathy was produced experimentally in the eye of the albino corydoras (one of the tropical fish) by daily administration of chloroquine (0.1 mg per os). The enucleated eyes were examined from the 14th day to 3 months after the beginning of drug administration under light and electron microscopy. The f...

journal_title：Ophthalmic research

authors： Matsumura M,Ohkuma M,Tsukahara I

更新日期：1986-01-01 00:00:00

abstract：:The eyes of 200 rats (Mol:SPRD, Moellegaard Ltd., Skensvet, Denmark), 8 weeks of age and of both sexes, were examined routinely with a photo-slitlamp microscope (Zeiss) and opthalmoscope (Heine) 3-4 times in the course of four different 12-week toxicity studies. The animals were kept under constant lighting conditions...

journal_title：Ophthalmic research

authors： Wegener A,Jochims K

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:Single-field non-mydriatic fundus photography (NMFP) has been used to detect diabetic retinopathy (DR) in many studies; however, its value in a general clinical setting has not been established. Here we performed a meta-analysis to evaluate its diagnostic effectiveness. METHOD:We systematically searched PubMed...

journal_title：Ophthalmic research

authors： Hu J,Chen R,Lu Y,Dou X,Ye B,Cai Z,Pu Z,Mou L

更新日期：2019-01-01 00:00:00

abstract：:The turnover and migration of synthesized glycoproteins in the cultured retinal pigment epithelium have been studied. Quantitative study indicated that half-time of 3H-fucosylglycoproteins was 11.6 days. Autoradiography was performed several times after incubation of 3H-fucose. Retinal pigment epithelium constantly sy...

journal_title：Ophthalmic research

authors： Entani S,Yoshimura N,Chihara E,Tsukahara I

更新日期：1986-01-01 00:00:00

abstract：:Toxoplasma gondii is an extremely successful opportunistic parasite which infects approximately one third of the human population worldwide. The impact of this parasite on human health becomes particularly manifest in congenital damage with infection and subsequent inflammation of neuronal tissues including the retina...

journal_title：Ophthalmic research

authors： Pleyer U,Schlüter D,Mänz M

更新日期：2014-01-01 00:00:00

abstract：:Cellular events in the rat conjunctiva were studied at 1, 6 and 24 h following the topical application of leukotriene B4. A significant increase was noted in the number of eosinophils (p less than 0.01) and neutrophils (p less than 0.05) at 1 h and only in eosinophils at 6 h after leukotriene B4 application at the 2-m...

journal_title：Ophthalmic research

authors： Trocmé SD,Gilbert CM,Allansmith MR,Bloch KJ,Abelson MB

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Myopia has become a worldwide public health issue, which is occurring at a younger age, leading to an increased risk of high myopia. Ocular complications associated with high myopia can lead to irreversible vision loss. It is urgent and critical to explore effective treatment to slow or even stop the progres...

journal_title：Ophthalmic research

authors： Wang S,Wang J,Wang N

更新日期：2020-08-11 00:00:00

abstract：PURPOSE:To investigate the role of integrin-linked kinase (ILK) in endothelial cell migration, proliferation and tube formation in vitro. MATERIALS AND METHODS:Cultured RF/6A cells were knocked down for ILK using small interfering RNA (siRNA). Cellular ILK expression was quantified by real-time quantitative PCR and We...

journal_title：Ophthalmic research

authors： Guo L,Yu W,Li X,Zhao G,He P

更新日期：2009-01-01 00:00:00

abstract：:Conventional Scheimpflug photography uses slits with a constant width of 80 microns. This parameter limits the resolution as sharp contours are imaged with a basic uncertainty. In order to reduce this basic uncertainty we developed an illumination slit with a width of 20 microns and less, using a green helium-neon las...

journal_title：Ophthalmic research

authors： Huebscher HJ,Möller DE,Seiler T

更新日期：1996-01-01 00:00:00