Abstract:
INTRODUCTION:The aim of this work was to describe the optical coherence tomography (OCT) angiography (OCTA) features in paediatric Leber-Coats disease. METHODS:Three children presenting with unilateral, clinically active Leber-Coats disease were evaluated using spectral domain OCT and OCTA. OCT angiograms were analysed and compared with the current literature. RESULTS:All 3 OCT angiograms showed that the vessels had lost most of their collateral branches and presented many loops. The capillaries were rarefied and anomalies in vessel size, vasodilatation, and macroaneurysms were evident. CONCLUSION:This is the first case series of OCTA performed in children with Leber-Coats disease. OCTA is a non-invasive and non-contact technique, which can be considered of fundamental importance for the diagnosis, clinical management, and follow-up of the disease.
journal_name
Ophthalmic Resjournal_title
Ophthalmic researchauthors
Fortunato M,Turtoro A,Cennamo Gdoi
10.1159/000478783subject
Has Abstractpub_date
2017-01-01 00:00:00pages
185-187issue
3eissn
0030-3747issn
1423-0259pii
000478783journal_volume
58pub_type
杂志文章abstract::To determine the effect of interleukin-10 (IL-10) and transforming growth factor-beta (TGF-beta) on the down-regulation of MHC class II antigens, bovine retinal pigment epithelial (RPE) cells were incubated with interferon-gamma (IFN-gamma) in different concentrations. Subsequently, the IFN-gamma pretreated RPE cells ...
journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000055545
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journal_title:Ophthalmic research
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journal_title:Ophthalmic research
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journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000113885
更新日期:2008-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000119877
更新日期:2008-01-01 00:00:00
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journal_title:Ophthalmic research
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journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265345
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journal_title:Ophthalmic research
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journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265224
更新日期:1982-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 临床试验,杂志文章,随机对照试验
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doi:10.1159/000265483
更新日期:1987-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000078780
更新日期:2004-07-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章
doi:10.1159/000265511
更新日期:1987-01-01 00:00:00
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更新日期:2011-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章
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更新日期:1985-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章,评审
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更新日期:2019-01-01 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章,评审
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更新日期:2020-07-16 00:00:00
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journal_title:Ophthalmic research
pub_type: 杂志文章
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journal_title:Ophthalmic research
pub_type: 杂志文章
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更新日期:1988-01-01 00:00:00