Abstract：
BACKGROUND:Coats' disease is an exudative retinal detachment with vascular telangiectasis occurring mostly in male children, the age group most affected by retinoblastoma. OBJECTIVES:Compare the differential diagnoses of Coats' disease Establish recommendation to early disease detection. MATERIALS AND METHODS:A 3-year-old female child was referred to Muhimbili National Hospital (MNH), Tanzania, in September 2011. She had presented at the peripheral hospital with gradual onset of left eye leukocoria for 1 year and pain for 2 months. B-scan showed a mass in the left eye. A clinical diagnosis of retinoblastoma was made. Left eye enucleation was performed; the patient was referred to MNH, with the enucleated specimen. RESULTS:Brain and orbits scan revealed no residual tumour. The globe measured 2 x 1.8 cm, the optic nerve stump measured 3 mm. A whitish mass filled the vitreous, with complete retinal detachment. Microscopy showed retinal gliosis, detachment with sub retinal PAS positive exudates, vacuolation and cholesterol clefts. Foreign body giant cells were present; telangiectatic thin-walled blood vessels were identified. Clinico-pathological findings were of stage 4 Coats' disease. CONCLUSION:Coats' disease is an important differential diagnosis of retinoblastoma. Delay to detect Coats' disease leads to vision loss which necessitates eye enucleation as was in this child.
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Rugwizangoga B,Mwabili T,Scanlan T,Meyer P,Kitinya Jdoi
10.4314/ahs.v14i3.37subject
Has Abstractpub_date
2014-09-01 00:00:00pages
763-8issue
3eissn
1680-6905issn
1729-0503pii
jAFHS.v14.i3.pg763journal_volume
14pub_type
杂志文章,评审abstract：Background:Induction of labour (IOL) is an obstetric procedure that should be conducted in a healthcare facility with the capacity to provide optimal care based on the patient risk status. Inadequate monitoring, untimely procedure and lack of readily available and experienced medical staff to participate in the care of...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v20i3.27
更新日期：2020-09-01 00:00:00
abstract：Background/Objective:In a project of telepathology (TP) between German pathologists and a hospital in Tanzania, trained technical assistants have uploaded digital histological images onto the internet-based platform ipath. The diagnoses from 486 paediatric specimens were analysed. Methods:The investigation included di...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v20i3.37
更新日期：2020-09-01 00:00:00
abstract：Background:Elabela (ELA) is a hormone that is secreted at high levels in the kidneys of a healthy adult. This study aims to investigate whether serum ELA levels of patients with Type 2 Diabetes vary with the severity of renal damage. Methods:Our study included 50 healthy control subjects and 100 diabetic patients, who...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v20i2.37
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Welders have been identified as a high risk group for eye disorders due to their exposure to ultraviolet radiation. OBJECTIVE:To determine the prevalence and types of eye diseases amongst welders in Ile-Ife, Osun state. METHODS:This is a cross sectional descriptive study of 405 consenting welders. Informat...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v12i2.21
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:HIV/AIDS epidemic and sexual assault have emerged as the most serious public health problems in South Africa. The country has about 5-million HIV infected individuals. About a million women are raped every year. OBJECTIVES:To study the incidence of HIV infection in victims of sexual assaults. DESIGN:This i...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.5555/afhs.2005.5.3.207
更新日期：2005-09-01 00:00:00
abstract：Background:Viral hemorrhagic fevers (VHF) refers to a group of febrile illnesses caused by different viruses that result in high mortality in animals and humans. Many risk factors like increased human-animal interactions, climate change, increased mobility of people and limited diagnostic facility have contributed to t...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v20i3.17
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Pyogenic osteomyelitis is still frequently seen in the developing world and the treatment of chronic osteomyelitis presents a considerable challenge despite advances in microbiological techniques, antibiotics and surgical techniques. Acute haematogenous osteomyelitis is commoner in children. RESULTS:In the ...
journal_title：African health sciences
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：Background:The hypercoagulability of pregnancy is exaggerated in pre-eclamptic state because of endothelial activation with resultant production of some endothelial derived proteins that are said to be inhibitors of fibrinolysis. This study compares these proteins like tPA, PAI-1 and D-dimers in normal pregnant women a...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v18i3.15
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Reduction in renal length was found to be an insufficient independent indicator of chronic renal disease. OBJECTIVE:To determine the ultrasound normative values of renal parenchymal thickness (RPT) among adults and correlate them with age and somatometric parameters. METHODS:This was a prospective clinic b...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v14i3.27
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Globally, and particularly in developing countries, the menace of anti-microbial resistance is an accelerating problem. In Nigeria, increase in bacterial resistance has been phenotypically established but due to high cost, few molecular studies have been reported. OBJECTIVES:This study screened for presence...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v17i2.9
更新日期：2017-06-01 00:00:00
abstract：Background:Impairment of peripheral skeletal muscle function is a common phenomenon in patients with cystic fibrosis (CF) in addition to great clinical connotations, such as lack of exercise tolerance and decrease of health-related quality of life. There is very limited data on the effects of maximal exercise on muscle...
journal_title：African health sciences
pub_type： 临床试验,杂志文章
doi：10.4314/ahs.v18i4.45
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVES:To investigate the pattern of referral for and utilisation of physiotherapy in the continuum of stroke care at a tertiary hospital in Ibadan, Nigeria. METHODS:Referral notes and medical records of patients admitted in the University College Hospital, Ibadan with a clinical diagnosis of stroke between Januar...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v17i1.11
更新日期：2017-03-01 00:00:00
abstract：Background:HIV causes a decrease in CD4+ lymphocyte cells count, exposing the individual to infections (urinary tract infections). This study was carried out to determine the prevalence of bacteriuria and antimicrobial susceptibility pattern of bacteria isolates among HIV patients. Methods:Clean catch mid-stream urine...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v20i3.7
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Recombinant human endostatin (Endostar) has been widely used to suppress angiogenesis in carcinoma patients. Hypertrophic scar (HS) tissue, much like a carcinoma, is often associated with angiogenesis. However, there have been few studies conducted on the effects of Endostar on HS or its mechanism. OBJECTIV...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v16i2.23
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Co-trimoxazole use is the standard of care for preventing Pneumocystis jirovecii pneumonia in sub-Saharan Africa but implementation remains slow. Co-trimoxazole is self- administered with uncertain adherence. Knowledge of co-trimoxazole use among HIV infected persons is unknown. OBJECTIVES:To assess knowled...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v15i1.7
更新日期：2015-03-01 00:00:00
abstract：Background:Type 2 diabetes mellitus is usually related to vascular problems and is associated with impairment in endothelial function characterized by impaired endothelial-dependent vasodilation and increased platelet adhesion. There is limitation in clinical studies that have addressed the beneficial effects of weight...
journal_title：African health sciences
pub_type： 杂志文章,随机对照试验
doi：10.4314/ahs.v18i4.5
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Day case surgery services are increasing all over the world. The prevalence of postoperative pain after day surgery is found to be high. Little is known about the prevalence of postoperative pain, in Kenya, after day case surgeries. OBJECTIVE:To investigate the prevalence of postoperative pain after day sur...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v13i3.36
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Malaria is on the increase due to emergence of parasite drug resistance and there is thus an urgent need for the development of new antiparasitic drugs effective at low concentrations. Ketolides antibiotics are used for treatment of various ailments and are relevant candidates to establish antiparasitic acti...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v15i4.28
更新日期：2015-12-01 00:00:00
abstract：:In this review of recent advances in nutrition, we shall follow the 'life cycle' with special attention to maternal and foetal nutrition, linear growth, and nutritional assessment. We also consider nutrition, infection and micronutrients, and recent concepts of the pathophysiology and management of protein energy maln...
journal_title：African health sciences
pub_type： 杂志文章,评审
doi：
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:Neurosyphilis is a common but often missed disease worldwide, mainly because it has many manifestations making its diagnosis difficult. It is often missed among HIV patients as the search for other co-infections such as toxoplasmosis often overshadows its consideration. OBJECTIVES:To describe one of our cas...
journal_title：African health sciences
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：Background:Acute myeloid leukemia (AML), an aggressive clonal disease, is genetically heterozygous. The prognostic role of expression of Breast Cancer Resistance Protein (BCRP) gene, which behaves as a multidrug transporter, in adult AML is ambiguous. Objective:The objective is to assess the level of mRNA expression o...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v18i4.15
更新日期：2018-12-01 00:00:00
abstract：Introduction:Chronic pain classification in HIV positive patients is essential for diagnosis and treatment. However, this is rarely done despite association with poor outcomes. Methods:A cross-sectional survey of 345 consented patients at a specialized HIV care center in Uganda was conducted. Chronic pain was defined ...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v19i2.20
更新日期：2019-06-01 00:00:00
abstract：Background:Malnutrition is an important clinical outcome amongst HIV patients in developing countries and in Uganda, there is scarcity of information on its prevalence and risk factors amongst HIV adult patients. Methods:A cross-sectional study amongst 253 HIV patients in Bushenyi district assessed their nutritional s...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v20i1.17
更新日期：2020-03-01 00:00:00
abstract：Objectives:Fungus Cordyceps militaris has been used as a herbal tonic in traditional Chinese medicine, which could be surface liquid-cultured for mycelia production. To evaluate the potential of polysaccharides obtained from mycelia of Cordyceps militaris (PS-MCM) for attenuation of side-effects of chemotherapy. Metho...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v19i2.40
更新日期：2019-06-01 00:00:00
abstract：Background:The use of illicit drugs has become a worldwide health problem. Substances with the potential to be abused may have direct or indirect effects on physiologic mechanisms that lead to organ system dysfunction and diseases. Objective:The present study aims to investigate the structural and reabsorption integri...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v18i3.35
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Caffeine one of the readily available stimulants consumed daily by more than 80% of the world's population, making it the most widely consumed drug in history. The objective of this study was to determine the effects of different doses (5, 10 &15 mg.kg(-1)) of caffeine per kilogram body weight on maximal aer...
journal_title：African health sciences
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Recent publications show that smoking and alcohol use among adolescents with unplanned pregnancy is increasing and the causes need to be further studied. OBJECTIVE:To determine the association between living in a non-intact family household and the presence of smokers and consumers of alcoholic beverages in...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v16i1.4
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Snake envenomation is a major public health problem of the Savannah regions of West Africa. Ocular manifestations of snakebites are rare with few reports documenting blindness as a complication. OBJECTIVE:To highlight an unusual manifestation of snake bites and its attendant problems. METHODS:A report of s...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v15i3.46
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Resistance to most antimalarial drugs has encouraged the use of herbal preparations along with prescribed orthodox drugs. OBJECTIVE:To investigate effect of co-administration of aqueous extract of T. occidentalis leaves; commonly used as antimalarial and haematinic agent in Nigeria and artesunate using P. b...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v13i4.16
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Lassa fever is a rodent-borne zoonosis that clinically manifests as an acute hemorrhagic fever. It is treated using ribavarin. Surviving Lassa fever without receiving the antiviral drug ribavarin is rare. Only few cases have been documented to date. CASE PRESENTATION:We report a case of a 59-year old female...
journal_title：African health sciences
pub_type： 杂志文章
doi：10.4314/ahs.v14i4.40
更新日期：2014-12-01 00:00:00
