Abstract:
Background:HIV causes a decrease in CD4+ lymphocyte cells count, exposing the individual to infections (urinary tract infections). This study was carried out to determine the prevalence of bacteriuria and antimicrobial susceptibility pattern of bacteria isolates among HIV patients. Methods:Clean catch mid-stream urine samples were collected from 135 HIV- seropositive patients, cultured on Cystein lactose electrolyte deficient (CLED) agar and incubated at 370C for 24 hours. The modified Kirby-Bauer's disc diffusion method was used to assess susceptibility to antimicrobial agents. Results:The prevalence of bacteriuria was 67.4% (91/135). Staphylococcus aureus was the most predominant (42.9%) isolate, followed by Escherichia. coli (24.2%), then Coagulase negative Staphylococci (10.9%). The highest proportion of bacteria was isolated from patients having a CD4+ T-cell count of less than 300 cells/mm3 (39.6%). There was an association between the level of CD4+cell count and bacterial urinary tract infection (P= 0.001). Most sensitive drugs were gentamycin, vancomycin and amoxicillin-clavulanic acid while the drug with the greatest resistance was sulphamethoxazole-trimethoprim, with Enterococcus and Proteus showing 100% resistance to this drug. Conclusion:Bacteriuria and resistance to commonly used antibiotics is prevalent among HIV/AIDS patients attending the Bamenda Regional Hospital. Therapy based on antimicrobial susceptibility test is encouraged.
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Samje M,Yongwa O,Enekegbe AM,Njoya Sdoi
10.4314/ahs.v20i3.7subject
Has Abstractpub_date
2020-09-01 00:00:00pages
1045-1052issue
3eissn
1680-6905issn
1729-0503pii
jAFHS.v20.i3.pg1045journal_volume
20pub_type
杂志文章abstract::Efforts to introduce and integrate the discipline of family medicine in sub-Saharan Africa have remained slow due to failure to understand what role and benefit such physicians can play in the existing health care systems in the region. An attempt is made here to explain reasons for this trend and suggest ways to over...
journal_title:African health sciences
pub_type: 信件
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pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:African health sciences
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
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pub_type: 杂志文章
doi:10.4314/ahs.v16i4.14
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pub_type: 杂志文章,多中心研究
doi:
更新日期:2004-04-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2011-06-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,多中心研究
doi:
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pub_type: 杂志文章
doi:
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v20i2.7
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pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2005-12-01 00:00:00
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更新日期:2012-09-01 00:00:00