Diagnosis and treatment of pyogenic bone infections.

Abstract:

BACKGROUND:Pyogenic osteomyelitis is still frequently seen in the developing world and the treatment of chronic osteomyelitis presents a considerable challenge despite advances in microbiological techniques, antibiotics and surgical techniques. Acute haematogenous osteomyelitis is commoner in children. RESULTS:In the pre-antibiotic era, mortality rate was high and progression to chronic osteomyelitis was common. A near similar scenario still exists in many developing countries due to the combination of inappropriate and/or inadequate antibiotic therapy, delayed presentation and unorthodox interventions by traditional healers. DISCUSSION:Chronic osteomyelitis may result from poorly treated or untreated acute osteomyelitis, open fractures, surgery for an array of orthopaedic conditions and from contiguous spread from infected soft tissue as may occur in diabetic foot infections. A large array of treatment techniques hinged on sequestrectomy/ debridement, management of dead space, improvement of oxygenation and perfusion to ischaemic tissue exist. Despite these, total eradication of disease is difficult. CONCLUSION:This article summarizes the pathology and methods of management available for pyogenic osteomyelitis. In its acute and chronic forms, the disease is likely to remain prevalent in the developing world until issues of ignorance, poverty and prompt access to appropriate and efficacious medical care are addressed.

journal_name

Afr Health Sci

journal_title

African health sciences

authors

Ikpeme IA,Ngim NE,Ikpeme AA

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

82-8

issue

1

eissn

1680-6905

issn

1729-0503

journal_volume

10

pub_type

杂志文章
  • ABCB1 variants C3435T and T129C are not associated with colorectal cancer risk.

    abstract:Background:Colorectal cancer (CRC) is one of the most prevalent cancers in Saudi Arabia that is highly characterized with poor survival rate and advanced metastasis. Many studies contribute this poor outcome to the expression of ABC transporters on the surface of cancer cells. Objectives:In this study, two ABCB1 varia...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v19i3.23

    authors: Al Qahtani AM,Al-Ghafari AB,Al Doghaither HA,Alzahrani AH,Omar UM,Rahimulddin SA

    更新日期:2019-09-01 00:00:00

  • Intestinal ameliorative effects of traditional Ogi-tutu, Vernonia amygdalina and Psidium guajava in mice infected with Vibrio cholera.

    abstract:BACKGROUND:Cholera, a severe acute watery diarrhea caused by Vibrio cholerae is endemic in Nigeria with most cases occurring in the rural areas. In South West Nigeria, some individuals resort to alternative treatments such as Ogi-tutu, Psidium guajava and Vernonia amygdalina during infections. The effectiveness of thes...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i2.33

    authors: Shittu OB,Ajayi OL,Bankole SO,Popoola TO

    更新日期:2016-06-01 00:00:00

  • Methodological challenges in a study on falls in an older population of Cape Town, South Africa.

    abstract:BACKGROUND:Falls are a major cause of disability, morbidity and mortality in older persons, but have been under researched in developing countries. OBJECTIVE:To describe challenges encountered in a community-based study on falls in a multi-ethnic population aged ≥65 years in a low-income setting. METHODS:The study wa...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v17i3.35

    authors: Kalula SZ,Ferreira M,Swingler GH,Badri M,Sayer AA

    更新日期:2017-09-01 00:00:00

  • Evaluation of Crimean-Congo hemorrhagic fever suspected cases admitted to a secondary care hospital in Kastamonu, Turkey between 2014-2017.

    abstract:Background:Crimean-Congo hemorrhagic fever (CCHF) is an endemic zoonosis in Kastamonu, Turkey. Clinical and laboratory findings may not be specific in the early phase of the disease, hence bringing a challenge to the clinician. Objective:We aimed to distinguish CCHF cases among all suspected cases by comparing them wi...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v19i1.16

    authors: Gozdas HT

    更新日期:2019-03-01 00:00:00

  • Salivary flow, amylase, and total protein in hospitalized patients with HIV infection / AIDS complications.

    abstract:Background:Saliva is a complex secretion produced daily by the salivary glands. Saliva consists mainly of water, enzymes, ions and amino acids and performs several important functions in oral health. Objective:The aim of this study was to investigate the flow rate and concentrations of amylase and total proteins in th...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i2.7

    authors: de Oliveira NC,de Oliveira TC,Klamas VC,Ventura MA,Kamei AA,Naka JY,Brancher JA,de Lima AAS

    更新日期:2020-06-01 00:00:00

  • Unorthodox ophthalmic preparations on the Ghanaian market: a potential risk for ocular and enteric infections.

    abstract:Purpose:Microbial contamination of orthodox ophthalmic preparations poses a serious threat to the user by causing ocular infections. There is no such information about unorthodox ophthalmic preparations in a medical pluralistic system such as Ghana. The aim of this study was to assess unorthodox ophthalmic medications ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i1.58

    authors: Kyei S,Dogbadze E,Tagoh S,Mwanza E

    更新日期:2020-03-01 00:00:00

  • Environmental barriers experienced by stroke patients in Musanze district in Rwanda: a descriptive qualitative study.

    abstract:BACKGROUND:Patients with stroke experience a number of environmental barriers, limiting their re-integration. Information regarding the barriers experienced by patients with stroke in a specific setting such as the Musanze district in Rwanda would assist with the development of rehabilitation programmes that would take...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Urimubenshi G,Rhoda A

    更新日期:2011-09-01 00:00:00

  • Hypoxemia predicts death from severe falciparum malaria among children under 5 years of age in Nigeria: the need for pulse oximetry in case management.

    abstract:BACKGROUND:Oxygen saturation is a good marker for disease severity in emergency care. However, studies have not considered its use in identifying individuals infected with Plasmodium falciparum at risk of deaths. OBJECTIVE:To investigate the prevalence and predictive value of hypoxaemia for deaths in under-5s with sev...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v14i2.16

    authors: Orimadegun A,Ogunbosi B,Orimadegun B

    更新日期:2014-06-01 00:00:00

  • The utility of the Helicobacter pylori stool antigen test in managing dyspepsia: an experience from a low resource setting.

    abstract:BACKGROUND:Dyspepsia is defined as a chronic or recurrent pain or discomfort centered in the upper abdomen. Endoscopy is the best strategy for confirming the cause of dyspepsia. Non- invasive strategies would be more appropriate in low resource countries where endoscopy is not readily available. However, there is conce...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v14i4.9

    authors: Segamwenge IL,Kagimu M,Ocama P,Opio K

    更新日期:2014-12-01 00:00:00

  • Is there any relationship between RDW levels and atrial fibrillation in hypertensive patient?

    abstract:BACKGROUND:Atrial fibrillation (AF) is the most common cardiac arrhythmia and increases the risk of stroke and death. Patients with hypertensive have an increased risk of developing atrial fibrillation. RDW (Red blood cell distribution width) levels are elevated in cardiovascular disorders including heart failure, stab...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v14i1.41

    authors: Sarikaya S,Şahin Ş,Akyol L,Börekçi E,Yilmaz YK,Altunkaş F,Karaman K

    更新日期:2014-03-01 00:00:00

  • Glanzmann's thrombasthenia: a rare bleeding disorder in a Nigerian girl.

    abstract:Introduction:Glanzmann's Thrombasthenia (GT) is a rare autosomal recessive bleeding disorder due to defective platelet membrane glycoprotein GP IIb/IIIa (integrin αIIbβ3). The prevalence is estimated at 1:1,000,000 and it is commonly seen in areas where consanguinity is high. Case Presentation:The authors report a 12 ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i2.27

    authors: Ezenwosu OU,Chukwu BF,Uwaezuoke NA,Ezenwosu IL,Ikefuna AN,Emodi IJ

    更新日期:2020-06-01 00:00:00

  • Ocular injuries and eye care seeking patterns following injuries among cocoa farmers in Ghana.

    abstract:BACKGROUND:The work environment of cocoa farmers exposes them to several ocular hazards that predispose them to eye diseases and injuries. However, the extent of ocular injuries and health seeking patterns following these injuries are unknown among cocoa farmers in Ghana. OBJECTIVES:To determine the prevalence of ocul...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i1.34

    authors: Bert BK,Rekha H,Percy MK

    更新日期:2016-03-01 00:00:00

  • Utility of albumin to creatinine ratio in screening for microalbuminuria among newly diagnosed diabetic patients in Uganda: a cross sectional study.

    abstract:Background:The aim of this study was to determine the prevalence and factors associated with microalbuminuria among newly diagnosed diabetic patients in Mulago National Referral Hospital, Uganda. Methods:In this cross-sectional study conducted between June 2014 and January 2015, we collected information on patients' s...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v19i1.36

    authors: Muddu M,Mutebi E,Ssinabulya I,Kizito S,Mulindwa F,Kiiza CM

    更新日期:2019-03-01 00:00:00

  • Hydroxyurea therapy in adult Nigerian sickle cell disease: a monocentric survey on pattern of use, clinical effects and patient's compliance.

    abstract:BACKGROUND:The clinical prospects of hydroxyurea therapy in the management of sickle cell disease (SCD) require evaluation in the Nigerian setting to develop indigenous guidelines. This survey examines the pattern of hydroxyurea therapy, its clinico-haematologic benefits and safety profile in Nigerian SCD subjects. ME...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v17i1.31

    authors: Adewoyin AS,Oghuvwu OS,Awodu OA

    更新日期:2017-03-01 00:00:00

  • Depression among medical students in Alexandria, Egypt.

    abstract:Background:Depression is a common illness worldwide with high rate among medical students. The objectives were to estimate the prevalence of depression among medical students in Alexandria, and identify its correlates. Methods:A cross-sectional study design was used. The study was conducted at the Faculty of Medicine,...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i3.47

    authors: Elsawy WIH,Sherif AAR,Attia MSED,El-Nimr NA

    更新日期:2020-09-01 00:00:00

  • Structural findings at hysterosalpingography in patients with infertility at two private clinics in Kampala, Uganda.

    abstract:INTRODUCTION:Hysterosalpingography (HSG) is still a commonly used investigation in the evaluation of the female genital tract and the main indication for HSG is infertility. OBJECTIVE:The purpose of this study was to find the pathology detected at HSG in patients with infertility in our setting. MATERIALS AND METHODS...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Kiguli-Malwadde E,Byanyima RK

    更新日期:2004-12-01 00:00:00

  • Biochemical markers of mineral bone disorder in South African patients on maintenance haemodialysis.

    abstract:BACKGROUND AND OBJECTIVE:Despite the high mortality and morbidity associated with abnormalities in mineral and bone metabolism in haemodialysis patients, there is limited data on the pattern of mineral bone disorder in African CKD population. Therefore, the purpose of this study was to describe the pattern of mineral b...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v17i2.19

    authors: Waziri B,Duarte R,Naicker S

    更新日期:2017-06-01 00:00:00

  • Recombinant human endostatin reduces hypertrophic scar formation in rabbit ear model through down-regulation of VEGF and TIMP-1.

    abstract:BACKGROUND:Recombinant human endostatin (Endostar) has been widely used to suppress angiogenesis in carcinoma patients. Hypertrophic scar (HS) tissue, much like a carcinoma, is often associated with angiogenesis. However, there have been few studies conducted on the effects of Endostar on HS or its mechanism. OBJECTIV...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i2.23

    authors: Wang P,Jiang LZ,Xue B

    更新日期:2016-06-01 00:00:00

  • Effect of mother support groups on nutritional status in children under two years of age in Laisamis village, Kenya.

    abstract:BACKGROUND:In tackling the ongoing malnutrition problem in many parts of Kenya, the government has initialized preventive actions such as mother support groups in order to improve health and nutrition among children. Few studies have evaluated the effectiveness of such intervention. OBJECTIVE:This study aimed at deter...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i4.4

    authors: Undlien M,Viervoll HA,Rostad B

    更新日期:2016-12-01 00:00:00

  • Diagnostic value of glypican-3 in alpha fetoprotein negative hepatocellular carcinoma patients.

    abstract:BACKGROUND:The prognosis of patients with hepatocellular carcinoma(HCC) is generally very poor with a 5-year survival rate of less than 15% since most of them are diagnosed clinically at their late stage. However, the differential diagnosis between alpha fetoprotein(AFP) negative HCC and cirrhotic nodules is still diff...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v13i3.26

    authors: Li B,Liu H,Shang HW,Li P,Li N,Ding HG

    更新日期:2013-09-01 00:00:00

  • Pattern and validity of clinical diagnosis of upper gastrointestinal diseases in south-west Nigeria.

    abstract:BACKGROUND:Diagnosis of upper gastrointestinal (UGI) diseases is often made on clinical grounds alone in Nigeria due to lack of endoscopic facilities. The validity of using such diagnosis is presently unknown. OBJECTIVE:The study aimed to determine: age and sex distribution of patients presenting for UGI endoscopy; pa...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.5555/afhs.2006.6.2.98

    authors: Agbakwuru EA,Fatusi AO,Ndububa DA,Alatise OI,Arigbabu OA,Akinola DO

    更新日期:2006-06-01 00:00:00

  • Actual and perceived substance use of health science students at a university in the Western Cape, South Africa.

    abstract:BACKGROUND:Substance use among youth is a worldwide epidemic that impacts negatively on the health sector as well as the family and society. Early student life is a time of tremendously high motivation to conform to the behaviours, values, and attitudes that are valued by the youth culture. They observe their peers' be...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Steyl T,Phillips J

    更新日期:2011-09-01 00:00:00

  • Neurologic infections in a Nigerian university teaching hospital.

    abstract:BACKGROUND:Neurologic infections are an important cause of morbidity and mortality especially worldwide but much more in the African continent. The frequency of the different types of neurologic infections and their mortality in this part of Nigeria is not known. OBJECTIVES:To review cases admitted into the main terti...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.5555/afhs.2006.6.1.55

    authors: Chapp-Jumbo EN

    更新日期:2006-03-01 00:00:00

  • Elabela levels in patients with type 2 diabetes: can it be a marker for diabetic nephropathy?

    abstract:Background:Elabela (ELA) is a hormone that is secreted at high levels in the kidneys of a healthy adult. This study aims to investigate whether serum ELA levels of patients with Type 2 Diabetes vary with the severity of renal damage. Methods:Our study included 50 healthy control subjects and 100 diabetic patients, who...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i2.37

    authors: Onalan E,Doğan Y,Onalan E,Gozel N,Buran I,Donder E

    更新日期:2020-06-01 00:00:00

  • The hazards of conducting induction of labour in high-risk pregnancies at district hospitals in low- and middle-income countries: lessons to learn from a case report.

    abstract:Background:Induction of labour (IOL) is an obstetric procedure that should be conducted in a healthcare facility with the capacity to provide optimal care based on the patient risk status. Inadequate monitoring, untimely procedure and lack of readily available and experienced medical staff to participate in the care of...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i3.27

    authors: Ngene NC,Moodley J

    更新日期:2020-09-01 00:00:00

  • Compliance with epidemic-prone diseases surveillance and response guidelines among health officers at surveillance units in South-West Nigeria.

    abstract:Introduction:Although compliance with surveillance guidelines is crucial to epidemic diseases control, determinants of use of these guidelines in Nigeria are poorly documented. We assess health workers compliance and factors associated with the surveillance and response guidelines for epidemic-prone diseases in South-W...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v18i2.28

    authors: Dairo MD,Afolayan DO,Akinyemi JO

    更新日期:2018-06-01 00:00:00

  • Opiate withdrawal syndrome in buprenorphine abusers admitted to a rehabilitation center in Tunisia.

    abstract:BACKGROUND:Illicit use of high dosage buprenorphine has been well documented in several countries, including Tunisia. OBJECTIVES:The aim of this survey is to assess the buprenorphine withdrawal syndrome time course, and how it may be affected by the population characteristics among subjects admitted to a rehabilitatio...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i4.24

    authors: Derbel I,Ghorbel A,Akrout FM,Zahaf A

    更新日期:2016-12-01 00:00:00

  • Baboons as potential reservoirs of zoonotic gastrointestinal parasite infections at Yankari National Park, Nigeria.

    abstract:BACKGROUND:Zoonoses pose a risk to public health. OBJECTIVE:To carry out the investigation of the prevalence of gastrointestinal parasites of baboons, Papio anubis, frequenting the Wikki base Camp in Yankari National Park, Nigeria. METHOD:Formol-ether concentration technique was used to isolate parasite eggs and cyst...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v13i2.7

    authors: Mafuyai HB,Barshep Y,Audu BS,Kumbak D,Ojobe TO

    更新日期:2013-06-01 00:00:00

  • Attitude of antenatal attendees to people living with HIV/AIDS in Uyo, south-south Nigeria.

    abstract:BACKGROUND:Stigmatization and discrimination of people living with HIV/AIDS has a negative impact on the global efforts to control the HIV/AIDS pandemic. Due to fear of stigmatization and discrimination, many people are reluctant to undergo voluntary counseling and testing, infected individuals are often unwilling to d...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Bassey EA,Abasiubong F,Ekanem U,Abasiatai AM

    更新日期:2007-12-01 00:00:00

  • Ecalmpsia: maternal and fetal outcome.

    abstract:OBJECTIVE:To determine the incidence of eclampsia and examine the maternal and fetal outcome. METHODS:A hundred and twenty consecutive admissions with eclampsia managed in Aminu Kano Teaching Hospital, Kano, Nigeria, were prospectively collated and analysed. Maternal and fetal morbidity and mortality were recorded. R...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v12i2.11

    authors: Jido TA

    更新日期:2012-06-01 00:00:00