Recombinant human endostatin reduces hypertrophic scar formation in rabbit ear model through down-regulation of VEGF and TIMP-1.

abstract：BACKGROUND:It has been shown that colorectal carcinoma is increasing in incidence in African countries. This could be due to change in life style. Molecular pathogenesis of colorectal cancer commonly involves mutation in p53 gene which leads to expression of p53 protein in tumor cells. Expression of p53 protein has bee...

journal_title：African health sciences

authors： Rambau PF,Odida M,Wabinga H

更新日期：2008-12-01 00:00:00

abstract：Introduction:Glanzmann's Thrombasthenia (GT) is a rare autosomal recessive bleeding disorder due to defective platelet membrane glycoprotein GP IIb/IIIa (integrin αIIbβ3). The prevalence is estimated at 1:1,000,000 and it is commonly seen in areas where consanguinity is high. Case Presentation:The authors report a 12 ...

journal_title：African health sciences

authors： Ezenwosu OU,Chukwu BF,Uwaezuoke NA,Ezenwosu IL,Ikefuna AN,Emodi IJ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:HIV/AIDS is a major public health problem in Cameroon which had a prevalence of 5.1% in 2010 with 141 new infections per day. The fear of voluntary counseling and testing (VCT) is an obstacle to HIV prevention. OBJECTIVES:To determine the prevalence of HIV-1, HIV-2 and HIV-1/HIV-2 co-infection among people ...

journal_title：African health sciences

authors： Nsagha DS,Njunda AL,Kamga HL,Assob JC,Bongkem EA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Upper gastrointestinal bleeding (UGIB) is a common emergency medical condition that may require hospitalization and resuscitation, and results in high patient morbidity. Upper gastrointestinal endoscopy is the preferred investigative procedure for UGIB because of its accuracy, low rate of complication, and i...

journal_title：African health sciences

authors： Alema ON,Martin DO,Okello TR

更新日期：2012-12-01 00:00:00

abstract：Background:Current evidence shows that the surge of sexually transmitted infections (STIs) is of public health importance. In Nigeria, about 3 million cases of STIs are reported annually with the highest rates observed among young people. Objective:This study was designed to investigate the knowledge, sexual behaviour...

journal_title：African health sciences

authors： Oharume IM

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:In tackling the ongoing malnutrition problem in many parts of Kenya, the government has initialized preventive actions such as mother support groups in order to improve health and nutrition among children. Few studies have evaluated the effectiveness of such intervention. OBJECTIVE:This study aimed at deter...

journal_title：African health sciences

authors： Undlien M,Viervoll HA,Rostad B

更新日期：2016-12-01 00:00:00

abstract：:In this review of recent advances in nutrition, we shall follow the 'life cycle' with special attention to maternal and foetal nutrition, linear growth, and nutritional assessment. We also consider nutrition, infection and micronutrients, and recent concepts of the pathophysiology and management of protein energy maln...

journal_title：African health sciences

authors： Duggan MB

更新日期：2003-12-01 00:00:00

abstract：:We report an inbred Tunisian family, in which the proband manifested signs of hypohidrotic ectodermal dysplasia, subtotal amelia, scoliosis and left renal agenesis. Two other family members had the full clinical criteria of hypohidrotic ectodermal dysplasia, characterized by deficient sweat glands, hypodontia, hypopla...

journal_title：African health sciences

authors： Al Kaissi A,Ben Chehida F,Nassib N,Safi H,Djnziri M,Ben Ghachem M,Gharbi H

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:In Uganda, morbidity and mortality among adolescent mothers and their children are high. Social factors behind this problem need to be better understood. OBJECTIVE:To explore problems that pregnant adolescents face in order to design appropriate policies and interventions. METHODS:This was a descriptive st...

journal_title：African health sciences

authors： Atuyambe L,Mirembe F,Johansson A,Kirumira EK,Faxelid E

更新日期：2005-12-01 00:00:00

abstract：Backgrounds:People in Yemen and in East African countries chew khat more than five hours daily. Objectives:The aim of this study was to assess the relationship between khat and occlusal caries progression. Methods:A cohort study was carried out among 98 Yemeni khat chewers and 101 non-chewers aged 18-35 years old wit...

journal_title：African health sciences

authors： Al-Alimi KR,Razak AAA,Saub R

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The progress in key maternal health indicators in the Eastern and Southern Africa Region (ESAR) over the past two decades has been slow. OBJECTIVE:This paper analyzed available information on nutrition programs and nutrition-specific interventions targeting maternal nutrition in the ESAR and proposes steps ...

journal_title：African health sciences

authors： Salam RA,Syed B,Syed S,Das JK,Zagre NM,Rayco-Solon P,Bhutta ZA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Noise induced hearing loss (NIHL) is within the top five occupational illnesses in Zimbabwe. Workers at a mining company complained about loss of hearing at the mine clinic. OBJECTIVE:To determine the prevalence of NIHL among employees at the Mine. METHODS:We conducted a descriptive cross sectional study a...

journal_title：African health sciences

authors： Chadambuka A,Mususa F,Muteti S

更新日期：2013-12-01 00:00:00

abstract：Background:Reconstruction of mandibular defects can be challenging because an acceptable aesthetic and functional outcome must be achieved simultaneously. Aim:To evaluate the pattern of mandibulectomy and reconstruction materials used in the reconstruction of mandibular defects. Materials and methods:This was a retro...

journal_title：African health sciences

authors： Braimah RO,Ibikunle AA,Abubakar U,Taiwo AO,Oboirien M,Adejobi FA,Ndubuisi TG,Abubakar S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Gunshot injuries were rare in Calabar before the Nigerian civil war. This has changed in subsequent years and has reached a near epidemic proportion in the last three years. These are caused by civil violence, police brutality and armed robberies. OBJECTIVE:To evaluate the incidence, pattern and causes of g...

journal_title：African health sciences

authors： Udosen AM,Etiuma AU,Ugare GA,Bassey OO

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To analyze gender differences in QOL of patients presenting at PHC centres and to identify the socio-demographic variables associated with poor QOL. METHODS:This was a cross-sectional study. Consecutive adult patients at outpatient departments of three PHC centres were eligible. Those selected were interview...

journal_title：African health sciences

authors： Muhwezi WW,Okello ES,Turiho AK

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The prognosis of patients with hepatocellular carcinoma(HCC) is generally very poor with a 5-year survival rate of less than 15% since most of them are diagnosed clinically at their late stage. However, the differential diagnosis between alpha fetoprotein(AFP) negative HCC and cirrhotic nodules is still diff...

journal_title：African health sciences

authors： Li B,Liu H,Shang HW,Li P,Li N,Ding HG

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Current strategies to overcome the global problem of antimicrobial resistance include research in finding new and innovative antimicrobials from plants. This study was carried out to determine the antibacterial activity of plant extracts of Olea africana stem-bark, Psidium guajava leaves, Vernonia amygdalina...

journal_title：African health sciences

authors： Cheruiyot KR,Olila D,Kateregga J

更新日期：2009-08-01 00:00:00

abstract：Background:The integrated approach to malaria prevention, which advocates for the use of several malaria prevention methods at households, is being explored to complement other existing strategies. We implemented a pilot project that promoted the integrated approach to malaria prevention in two rural communities in Wak...

journal_title：African health sciences

authors： Musoke D,Karani G,Morris K,Ndejjo R,Atusingwize E,Guwatudde D,Musoke MB

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The world has been experiencing an increase of stroke among young adults. Occurrence of stroke in young adults dramatically affects the quality of life of the individuals. OBJECTIVES:To investigate the quality of life amongst young adults who experienced a stroke living in Kenya. METHODS:A cross-sectional ...

journal_title：African health sciences

authors： Muli G,Rhoda A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Substance use among youth is a worldwide epidemic that impacts negatively on the health sector as well as the family and society. Early student life is a time of tremendously high motivation to conform to the behaviours, values, and attitudes that are valued by the youth culture. They observe their peers' be...

journal_title：African health sciences

authors： Steyl T,Phillips J

更新日期：2011-09-01 00:00:00

abstract：Background:Normative information on the breastfeeding of term newborns may guide clinicians in early identification of breastfeeding difficulties and oro-pharyngeal dysphagia (OPD), and may support optimal breastfeeding practices. Objective:To describe breastfeeding skills of term newborn infants in a South African ho...

journal_title：African health sciences

authors： Krüger EE,Kritzinger AA,Pottas LL

更新日期：2019-09-01 00:00:00

abstract：Background:Mulago Hospital is a high volume referral hospital under the Makerere University School of Medicine and Health Sciences. Basic obstetric ultrasound is a useful skill that can aid patient care. Objectives:The purpose of the study was to assess the effectiveness of an intervention implemented to teach basic u...

journal_title：African health sciences

authors： Ahmadzia H,Cigna S,Namagembe I,Macri C,Galerneau F,Magriples U

更新日期：2018-03-01 00:00:00

abstract：Background:The use of illicit drugs has become a worldwide health problem. Substances with the potential to be abused may have direct or indirect effects on physiologic mechanisms that lead to organ system dysfunction and diseases. Objective:The present study aims to investigate the structural and reabsorption integri...

journal_title：African health sciences

authors： El-Safty I,Eltamany E,Shouman A,El-Gamel O,Nada A,Ali W

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:The impact and management of HIV/AIDS in Lesotho in the context of disaster management was investigated. OBJECTIVES:Lesotho health care workers' perception on HIV/AIDS progression, whether HIV/AIDS was managed as a disaster, and the impact on the demographic profile was investigated. METHODS:The empirical ...

journal_title：African health sciences

authors： Belle JA,Ferriera SB,Jordaan A

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Neurologic infections are an important cause of morbidity and mortality especially worldwide but much more in the African continent. The frequency of the different types of neurologic infections and their mortality in this part of Nigeria is not known. OBJECTIVES:To review cases admitted into the main terti...

journal_title：African health sciences

authors： Chapp-Jumbo EN

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The increasing protection gaps of insecticide-treated nets and indoor-residual spraying methods against malaria have led to an emergence of residual transmission in sub-Saharan Africa and thus, supplementary strategies to control mosquitoes are urgently required. OBJECTIVE:To assess household environmental ...

journal_title：African health sciences

authors： Semakula HM,Song G,Zhang S,Achuu SP

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Non-traumatic perforation of the small bowel is an uncommon serious complication associated with high morbidity and mortality. Diseases that cause small bowel perforation vary in different areas of the world. OBJECTIVE:To highlight difficulties in the diagnosis and management of non-traumatic perforation of...

journal_title：African health sciences

authors： Eid HO,Hefny AF,Joshi S,Abu-Zidan FM

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Recent publications show that smoking and alcohol use among adolescents with unplanned pregnancy is increasing and the causes need to be further studied. OBJECTIVE:To determine the association between living in a non-intact family household and the presence of smokers and consumers of alcoholic beverages in...

journal_title：African health sciences

authors： Francisco VN,Carlos VR,Eliza VR,Octelina CR,Maria II

更新日期：2016-03-01 00:00:00

abstract：INTRODUCTION:Overwhelming evidence implicates Helicobacter pylori (H. pylori) as an etiologic agent of gastrointestinal diseases including gastric cancer. The mode of transmission of this pathogen remains poorly understood. OBJECTIVE:This investigation is to establish the presence of H. pylori in the waters of the Nai...

journal_title：African health sciences

authors： Dinda V,Kimang'a A

更新日期：2016-03-01 00:00:00

abstract：Background:Impairment of peripheral skeletal muscle function is a common phenomenon in patients with cystic fibrosis (CF) in addition to great clinical connotations, such as lack of exercise tolerance and decrease of health-related quality of life. There is very limited data on the effects of maximal exercise on muscle...

journal_title：African health sciences

authors： Abdelbasset WK,Soliman GS,Elshehawy AA,Alrawaili SM

更新日期：2018-12-01 00:00:00