Co-occurrence of Helicobacter pylori with faecal bacteria in Nairobi river basin: public health implications.

Abstract:

INTRODUCTION:Overwhelming evidence implicates Helicobacter pylori (H. pylori) as an etiologic agent of gastrointestinal diseases including gastric cancer. The mode of transmission of this pathogen remains poorly understood. OBJECTIVE:This investigation is to establish the presence of H. pylori in the waters of the Nairobi river basin and the predictive value the presence of fecal indicator bacteria would have for H. pylori. METHODOLOGY:Physical, chemical and biological assessment of water quality of rivers in Nairobi were carried out using standard methods. H. pylori DNA in water was detected using highly specific primers of glmM gene (294pb). RESULTS:There was high presence of faecal bacteria in the waters sampled. H. pylori DNA was detected in two domestic wells and one river. The wells were located in two different regions of the water basin but influenced by similar human activities. CONCLUSION:The high presence of faecal bacteria in the waters sampled did not parallel the H. pylori detection in the same waters. H. pylori was detected in the Nairobi river basin, but there was no relationship between the numerical levels of fecal bacteria and H. pylori.

journal_name

Afr Health Sci

journal_title

African health sciences

authors

Dinda V,Kimang'a A

doi

10.4314/ahs.v16i1.24

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

177-82

issue

1

eissn

1680-6905

issn

1729-0503

pii

jAFHS.v16.i1.pg177

journal_volume

16

pub_type

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