Postirradiation glucan administration enhances the radioprotective effects of WR-2721.

abstract：:In this study, we investigated the accuracy of using off-line bioluminescence imaging (BLI) and tomography (BLT) to guide irradiation of small soft tissue targets on a small animal radiation research platform (SARRP) with on-board cone beam CT (CBCT) capability. A small glass bulb containing BL cells was implanted as ...

journal_title：Radiation research

authors： Tuli R,Armour M,Surmak A,Reyes J,Iordachita I,Patterson M,Wong J

更新日期：2013-02-22 00:00:00

abstract：:A significant fraction of DNA damage produced by ionizing radiation comes from free radicals generated during the radiolysis of water, that is, by indirect effects. The hydroxyl radical, the principal damaging species, produces single-strand breaks and a plethora of base and sugar lesions that can be cytotoxic or muta...

journal_title：Radiation research

authors： Wallace SS

更新日期：1998-11-01 00:00:00

abstract：:Chromatid breaks have previously been shown to be induced in G2-phase cells after exposure to ionizing radiation (X and gamma rays) as a linear function of dose, consistent with a single-event mechanism. DNA double-strand breaks (DSBs) are thought to be the initiating lesion, and experiments with a genetically enginee...

journal_title：Radiation research

authors： Bryant PE,Jones C,Armstrong G,Frankenberg-Schwager M,Frankenberg D

更新日期：2003-02-01 00:00:00

abstract：:Clinicians involved in conventional radiation therapy are very concerned about the dose-response relationships of normal tissues. Before proceeding to new clinical protocols, radiation biologists involved with conformal proton therapy believe it is necessary to quantify the dose response and tolerance of the organs an...

journal_title：Radiation research

authors： Kubínová L,Mao X,Janácek J,Archambeau JO

更新日期：2003-07-01 00:00:00

abstract：:Rat females were exposed to a single 4.0-Gy gamma-ray dose and treated postradiation with a mixture of ATP-AET-mexamine at daily doses of 24, 12, and 3 mg/kg body wt, respectively, in drinking water throughout the period of their survival. With the radiation dose used, life shortening appeared primarily attributable t...

journal_title：Radiation research

authors： Benova DK,Kiradzhiev GD,Troitskaya MN,Anisimov VN

更新日期：1985-01-01 00:00:00

abstract：:Flynn, A. A., Green, A. J., Pedley, R. B., Boxer, G. M., Boden, R. and Begent, R. H. J. A Mouse Model for Calculating the Absorbed Beta-Particle Dose from (131)I- and (90)Y-Labeled Immunoconjugates, Including a Method for Dealing with Heterogeneity in Kidney and Tumor. Radiat. Res. 156, 28-35 (2001). Conventional inte...

journal_title：Radiation research

authors： Flynn AA,Green AJ,Pedley RB,Boxer GM,Boden R,Begent RH

更新日期：2001-07-01 00:00:00

abstract：:Monte Carlo simulations are used in the development of a nanotechnology-based multi-pixel beam array small animal microirradiation system. The microirradiation system uses carbon nanotube field emission technology to generate arrays of individually controllable X-ray pixel beams that electronically form irregular irra...

journal_title：Radiation research

authors： Schreiber EC,Chang SX

更新日期：2009-03-01 00:00:00

abstract：:Cells from an infinite-life-span near-diploid human fibroblast cell strain, MSU-1.1, were transformed after a single exposure to 60Co gamma radiation. The frequency of transformation as measured by the number of induced foci per 10(6) cells was a linear function of dose. Cells from 13 independent foci from gamma-irrad...

journal_title：Radiation research

authors： O'Reilly S,Walicka M,Kohler SK,Dunstan R,Maher VM,McCormick JJ

更新日期：1998-11-01 00:00:00

abstract：:Several studies over recent years have highlighted the possibility that radiation can induce transmissible genomic instability. Most of these involve in vitro irradiation and usually in vitro culture. Here it is reported that the short-half-life bone-seeking alpha-particle emitter (224)Ra did not induce excess transmi...

journal_title：Radiation research

authors： Bouffler SD,Haines JW,Edwards AA,Harrison JD,Cox R

更新日期：2001-02-01 00:00:00

abstract：:We have investigated tumor response to low-dose-rate irradiation from an implanted 125I source alone or in conjunction with intratumoral drug administration. The drug (cis-DDP or 5-FU) was incorporated homogeneously into the co-polymer CPP-SA, 20:80, and the polymer/drug rods were implanted in the RIF-1 fibrosarcomas ...

journal_title：Radiation research

authors： Berrada M,Yang Z,Lehnert SM

更新日期：2004-07-01 00:00:00

abstract：:Ionizing radiations induce mutations which can be detected both in coding sequences (Hprt locus) by measuring the frequency of 6-thioguanine-resistant cells and in minisatellite sequences by DNA fingerprint analysis. We analyzed the effects of irradiation with low-energy protons (31 keV/pm) and, for comparison, with u...

journal_title：Radiation research

authors： Ogheri S,Bruna V,Cera F,Favaretto S,Cherubini R,Celotti L

更新日期：1997-09-01 00:00:00

abstract：:A recent publication by Leith et al. (Cancer Res. 51, 4111-4113, 1991) showed that administration of epidermal growth factor (EGF) (0.25 mg/kg; q.i.d. x 7) to mice bearing xenografted A431 human epidermoid cancers produced increased tumor growth and a reduction of the percentage of hypoxic cells within neoplasms. In c...

journal_title：Radiation research

authors： Leith JT,Padfield G,Michelson S

更新日期：1992-11-01 00:00:00

abstract：:The toxicity of 137Cs in the beagle dog was investigated at the Inhalation Toxicology Research Institute (ITRI) and Argonne National Laboratory (ANL) as part of programs to evaluate the biological effects of both radionuclides in atomic bomb fallout and internally deposited fission-product radionuclides. In the ITRI s...

journal_title：Radiation research

authors： Nikula KJ,Muggenburg BA,Griffith WC,Carlton WW,Fritz TE,Boecker BB

更新日期：1996-11-01 00:00:00

abstract：:We previously reported that a priming dose of 0.3 Gy on gestation day 11 significantly increased the rate of living fetuses and reduced the incidence of congenital malformations caused by exposure to 5 Gy X rays on gestation day 12 in ICR mice. In the present study, postnatal development of the live offspring was inve...

journal_title：Radiation research

authors： Wang B,Ohyama H,Haginoya K,Odaka T,Itsukaichi H,Nose M,Nakajima T,Yukawa O,Yamada T,Hayata I

更新日期：1999-08-01 00:00:00

abstract：:The adaptive response to ionizing radiation may be mediated by the induction of antioxidant defense mechanisms, accelerated repair or altered cell cycle progression after the conditioning dose. To gain new insight into the mechanism of the adaptive response, nondividing lymphocytes and fibroblasts were used to elimina...

journal_title：Radiation research

authors： Cramers P,Atanasova P,Vrolijk H,Darroudi F,van Zeeland AA,Huiskamp R,Mullenders LH,Kleinjans JC

更新日期：2005-10-01 00:00:00

abstract：:In boron neutron capture therapy, the absorbed dose from the (10)B(n,alpha)(7)Li reaction depends on the (10)B concentration and (10)B distribution in the irradiated volume. Thus compounds used in BNCT should have tumor-specific uptake and low accumulation in normal tissues. This study compares in a mouse model the (1...

journal_title：Radiation research

authors： Wittig A,Huiskamp R,Moss RL,Bet P,Kriegeskotte C,Scherag A,Hilken G,Sauerwein WA

更新日期：2009-10-01 00:00:00

abstract：:Astronauts traveling outside Earth's magnetosphere risk exposure to charged particle radiation that may cause neurophysiological changes and behavioral deficits. Although proton particles comprise a large portion of the space radiation environment, little has been published on the effects of low-dose proton radiation ...

journal_title：Radiation research

authors： Bellone JA,Rudobeck E,Hartman RE,Szücs A,Vlkolinský R

更新日期：2015-08-01 00:00:00

abstract：:New data are given on the use of oxalic acid, in light and heavy water solutions, for in-pile chemical dosimetry. The method of calculating the absorbed doses in low-Z materials is described. Results of chemical measurements in the core of the heavy-water-moderated reactor at Vinca (Yugoslavia) are compared with the r...

journal_title：Radiation research

authors： Marković V,Draganić I

更新日期：1968-12-01 00:00:00

abstract：:Based on encouraging results from several early-phase clinical trials, there is renewed interest in the use of pharmacological ascorbate (i.e., intravenous administration resulting in >≈10 mM plasma ascorbate concentrations) in combination with standard-of-care cancer treatments including radiation and/or chemotherapy...

journal_title：Radiation research

authors： Petronek MS,Wagner BA,Hollenbeck NJ,Caster JM,Spitz DR,Cullen JJ,Buettner GR,Allen BG

更新日期：2019-06-01 00:00:00

abstract：:Acute thermotolerance was induced in Chinese hamster ovary cells by heating at 43 degrees C for 45 min followed by incubation at 37 degrees C for up to 85 h. The degree of thermotolerance induced was quantified by a second heat exposure at 43 degrees C. To study the interaction of thermotolerance and thermosensitizati...

journal_title：Radiation research

authors： Jung H

更新日期：1994-09-01 00:00:00

abstract：:Chomentowski, M., Kellerer, A. M. and Pierce, D. A. Radiation Dose Dependences in the Atomic Bomb Survivor Cancer Mortality Data: A Model-Free Visualization. The standard approach to obtaining nominal risk coefficients for radiation-related cancer involves fitting linear or linear-quadratic dose-response functions. Th...

journal_title：Radiation research

authors： Chomentowski M,Kellerer AM,Pierce DA

更新日期：2000-03-01 00:00:00

abstract：:Tritium that is bound to organic molecules is of special risk for living systems, in particular when such molecules are components of the cell nucleus. Therefore, [3H]thymidine and [3H]arginine were studied for radiotoxicity in early mammalian embryo development. Starting with the two-cell stage, mouse embryos were in...

journal_title：Radiation research

authors： Müller WU,Streffer C,Molls M,Glück L

更新日期：1987-05-01 00:00:00

abstract：:Synthetic lysophospholipids represent a variety of analogs of the naturally occurring 2-lysophosphatidylcholine. Some of these compounds showed significant therapeutic effects on the survival of mice following radiation injury when administered after various doses of whole-body X irradiation. Such therapeutic effects ...

journal_title：Radiation research

authors： Berdel WE,Schick P,Sedlmeier H,Fink U,Rastetter J,Messerschmidt O

更新日期：1983-04-01 00:00:00

abstract：:Normal human fibroblasts in plateau phase ( congruent with 95% G(1) phase) were stained with the vital nuclear dye Hoechst 33342 (blue fluorescence) or the vital cytoplasmic dye Cell Tracker Orange (orange fluorescence) and plated at a ratio of 1:1. Only the blue-fluorescing nuclei were microbeam-irradiated with a def...

journal_title：Radiation research

authors： Ponnaiya B,Jenkins-Baker G,Brenner DJ,Hall EJ,Randers-Pehrson G,Geard CR

更新日期：2004-10-01 00:00:00

abstract：:The concept of curvature in dose-response relationships figures prominently in radiation biology, encompassing a wide range of interests including radiation protection, radiotherapy and fundamental models of radiation action. In this context, the ability to detect even small amounts of curvature becomes important. Sta...

journal_title：Radiation research

authors： Shuryak I,Loucas BD,Cornforth MN

更新日期：2017-01-01 00:00:00

abstract：:The acute effects of proton whole-body irradiation on the distribution and function of leukocyte populations in the spleen and blood were examined and compared to the effects of photons derived from a (60)Co gamma-ray source. Adult female C57BL/6 mice were exposed to a single dose (3 Gy at 0.4 Gy/min) of protons at sp...

journal_title：Radiation research

authors： Kajioka EH,Andres ML,Li J,Mao XW,Moyers MF,Nelson GA,Slater JM,Gridley DS

更新日期：2000-05-01 00:00:00

abstract：:The relationship between binucleate cell formation and the loss of colony-forming ability was examined in several cultured mammalian cell lines irradiated with X rays. The maximum fraction of binucleate cells after X irradiation increased dose-dependently within the range in which reproductive cell death might predomi...

journal_title：Radiation research

authors： Sasaki H,Yoshinaga H,Kura S

更新日期：1986-12-01 00:00:00

abstract：:The relationship of ionizing radiation to the age-related ophthalmological findings of the 1978-1980 ophthalmological examination of A-bomb survivors of Hiroshima and Nagasaki has been reanalyzed using DS86 eye organ dose estimates. The main purpose of this reevaluation was to determine whether age and radiation expos...

journal_title：Radiation research

authors： Otake M,Finch SC,Choshi K,Takaku I,Mishima H,Takase T

更新日期：1992-09-01 00:00:00

abstract：:Therapeutic irradiation of the brain can cause a progressive cognitive dysfunction that may involve defects in neurogenesis. In an effort to understand the mechanisms underlying radiation-induced stem cell dysfunction, neural precursor cells isolated from the adult rat hippocampus were analyzed for acute (0-24 h) and ...

journal_title：Radiation research

authors： Limoli CL,Giedzinski E,Rola R,Otsuka S,Palmer TD,Fike JR

更新日期：2004-01-01 00:00:00

abstract：:This commentary considers modulation as a factor of potential biological importance in assessment of risk of radiofrequency (RF) energy emitted by communications systems and other technologies. Modulation introduces a spread of frequencies into a carrier waveform, but in nearly all cases this spread is small compared ...

journal_title：Radiation research

authors： Foster KR,Repacholi MH

更新日期：2004-08-01 00:00:00